Barrett, The Honors College at Arizona State University proudly showcases the work of undergraduate honors students by sharing this collection exclusively with the ASU community.

Barrett accepts high performing, academically engaged undergraduate students and works with them in collaboration with all of the other academic units at Arizona State University. All Barrett students complete a thesis or creative project which is an opportunity to explore an intellectual interest and produce an original piece of scholarly research. The thesis or creative project is supervised and defended in front of a faculty committee. Students are able to engage with professors who are nationally recognized in their fields and committed to working with honors students. Completing a Barrett thesis or creative project is an opportunity for undergraduate honors students to contribute to the ASU academic community in a meaningful way.

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Description
Lower termites are classified as termites that require a symbiotic relationship with their hindgut community of single-celled protozoa in order to gather nutrients to survive. The class Spirotrichonymphea is one of the six classes of protists that make up the Phylum Parabasalia. Within the class Spirotrichonymphea, there are 3 families

Lower termites are classified as termites that require a symbiotic relationship with their hindgut community of single-celled protozoa in order to gather nutrients to survive. The class Spirotrichonymphea is one of the six classes of protists that make up the Phylum Parabasalia. Within the class Spirotrichonymphea, there are 3 families and 11 genera. In this study, the Spirotrichonympha, Spironympha, and Microjoenia genera (family Spirotrichonymphidae), Holomastigotes genus (family Holomastigotidae), along with a new genus Brugerollea were targeted for molecular analysis. Protist cells were collected from Reticulitermes tibialis (Rhinotermitidae), Hodotermopsis sjostedti (Archotermopsidae), and Paraneotermes simplicornis (Kalotermidiae). Most molecular phylogenetic studies of termite-associated protists have used the 18S rRNA gene, however, there have been some ambiguities in the phylogeny of this gene. EF1-α, also known as EF1A, is a protein whose sequence can additionally be used to study the evolution of protists. EF1-α gene sequences were obtained from isolated protist cells by reverse transcription PCR (RT-PCR). Additionally, the 18S rRNA gene was amplified to confirm the isolated cells’ identity and compare the two phylogenetic methods, to see which would better resolve phylogenetic ambiguities. Sequences were compiled into an alignment for each target gene, and then a maximum likelihood tree was created for each using RAxML. Results from both trees supports the monophyly of Spirotrichonymphea and the polyphyly of genus Spirotrichonympha. However, neither gene fully resolves the phylogeny of Spirotrichonymphea.
ContributorsNguyen, Keana (Author) / Gile, Gillian (Thesis director) / De Martini, Francesca (Committee member) / Taerum, Stephen Joshua (Committee member) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
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Description
Bats (order Chiroptera) are the longest lived mammals for their size, with particularly extreme longevity evolving in the family Vespertilionidae, or vesper bats. Because of this, researchers have proposed using bats to study ageing and cancer suppression. Here, we study gene duplications across mammalian genomes and show that, similar to

Bats (order Chiroptera) are the longest lived mammals for their size, with particularly extreme longevity evolving in the family Vespertilionidae, or vesper bats. Because of this, researchers have proposed using bats to study ageing and cancer suppression. Here, we study gene duplications across mammalian genomes and show that, similar to previous findings in elephants, bats have experienced duplications of the tumor suppressor gene TP53, including five genomic copies in the genome of the little brown bat (Myotis lucifugus) and two copies in Brandt's bat (Myotis brandtii). These species can live 37 and 41 years, respectively, despite having an adult body mass of only ~7 grams. We use evolutionary genetics and next generation sequencing approaches to show that positive selection has acted on the TP53 locus across bats, and two recently duplicated TP53 gene copies in the little brown bat are both highly conserved and expressed, suggesting they are functional. We also report an extraordinary genomic copy number expansion of the tumor suppressor gene FBXO31 in the common ancestor of vesper bats which accelerated in the Myotis lineage, leading to 34\u201457 copies and the expression of 20 functional FBXO31 homologs in Brandt's bat. As FBXO31 directs the degradation of MDM2, which is a negative regulator of TP53, we suggest that increased expression of both FBXO31 and TP53 may be related to an enhanced DNA-damage response to genotoxic stress brought on by long lifespans and rapid metabolic rates in bats.
ContributorsSchneider-Utaka, Aika Kunigunda (Author) / Maley, Carlo (Thesis director) / Wilson Sayres, Melissa (Committee member) / Tollis, Marc (Committee member) / School of Life Sciences (Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2018-12
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Description
The 2017-2018 Influenza season was marked by the death of 80,000 Americans: the highest flu-related death toll in a decade. Further, the yearly economic toll to the US healthcare system and society is on the order of tens of billions of dollars. It is vital that we gain a better

The 2017-2018 Influenza season was marked by the death of 80,000 Americans: the highest flu-related death toll in a decade. Further, the yearly economic toll to the US healthcare system and society is on the order of tens of billions of dollars. It is vital that we gain a better understanding of the dynamics of influenza transmission in order to prevent its spread. Viral DNA sequences examined using bioinformatics methods offer a rich framework with which to monitor the evolution and spread of influenza for public health surveillance. To better understand the influenza epidemic during the severe 2017-2018 season, we established a passive surveillance system at Arizona State University’s Tempe Campus Health Services beginning in January 2018. From this system, nasopharyngeal samples screening positive for influenza were collected. Using these samples, molecular DNA sequences will be generated using a combined multiplex RT-PCR and NGS approach. Phylogenetic analysis will be used to infer the severity and temporal course of the 2017-2018 influenza outbreak on campus as well as the 2018-2019 flu season. Through this surveillance system, we will gain knowledge of the dynamics of influenza spread in a university setting and will use this information to inform public health strategies.
ContributorsMendoza, Lydia Marie (Author) / Scotch, Matthew (Thesis director) / Hogue, Brenda (Committee member) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description

Chameleons are notoriously a difficult species to provide proper husbandry for in captivity. They are an extremely intriguing species that has been gaining popularity among HERP enthusiasts, but the difficulty of care is deterring owners from these wonderful creatures. Building a proper enclosure takes a lot of time to plan

Chameleons are notoriously a difficult species to provide proper husbandry for in captivity. They are an extremely intriguing species that has been gaining popularity among HERP enthusiasts, but the difficulty of care is deterring owners from these wonderful creatures. Building a proper enclosure takes a lot of time to plan and research. Then to gather all the different supplies and to build the enclosure takes even longer. New or inexperienced chameleon owners tend to build improper enclosures, and this can be detrimental to a chameleon's health. My small business provides an online service that allows a building experience custom to my clients’ new friend’s needs.

ContributorsLagasse, Samantha (Author) / Byrne, Jared (Thesis director) / Baleen, Rachel (Committee member) / Yang, Andrea (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor)
Created2023-05
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Description

Our Founders Lab group created a pop-up thrift store on campus using donated clothing. We generated over $1000 in profits from our clothing sales to donate to a local charity, making our team the top-earning Founders Lab team. Our shop, Devils Rack, tabled twice on the Tempe ASU campus in

Our Founders Lab group created a pop-up thrift store on campus using donated clothing. We generated over $1000 in profits from our clothing sales to donate to a local charity, making our team the top-earning Founders Lab team. Our shop, Devils Rack, tabled twice on the Tempe ASU campus in order to generate our revenue.

ContributorsSoble, Lena (Author) / Haffner, Amanda (Co-author) / Walsh, Elizabeth (Co-author) / Burton, Tanner (Co-author) / Steffes, Keelyn (Co-author) / Byrne, Jared (Thesis director) / Lee, Christopher (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor)
Created2023-05
Description

Volunteers at Hand is an inclusive platform that focuses on creating an interconnected community of volunteers while providing an efficient and effective system that categorizes volunteer/service opportunities based on individual interests. The primary focus of our platform is to foster a compassionate community of individuals who will inspire each other

Volunteers at Hand is an inclusive platform that focuses on creating an interconnected community of volunteers while providing an efficient and effective system that categorizes volunteer/service opportunities based on individual interests. The primary focus of our platform is to foster a compassionate community of individuals who will inspire each other as well as others, and provide hope through their contributions towards helping and healing people. The foundation of Volunteers at Hand will be established through development of an elaborate platform/website that would be equally and openly accessible to all individuals and organizations interested in contributing efforts towards volunteer/service experiences. The platform will implement a filtering system that would categorize service opportunities and events based on personal preferences and interests, thus enabling a more efficient and effective method of discovering various opportunities that an individual would be passionate in contributing their efforts towards. Our platform would also implement a community based aspect that fosters further communication and interactions amongst volunteers as well as organizations involved in volunteer/service experiences.

ContributorsMurshed, Faiyaj (Author) / Salahuddin, Ibtesam (Co-author) / Byrne, Jared (Thesis director) / Surmacz, Amaris (Committee member) / Young, Andrea (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor) / Department of Psychology (Contributor)
Created2023-05
Description

Volunteers at Hand is an inclusive platform that focuses on creating an interconnected community of volunteers while providing an efficient and effective system that categorizes volunteer/service opportunities based on individual interests. The primary focus of our platform is to foster a compassionate community of individuals who will inspire each other

Volunteers at Hand is an inclusive platform that focuses on creating an interconnected community of volunteers while providing an efficient and effective system that categorizes volunteer/service opportunities based on individual interests. The primary focus of our platform is to foster a compassionate community of individuals who will inspire each other as well as others, and provide hope through their contributions towards helping and healing people. The foundation of Volunteers at Hand will be established through development of an elaborate platform/website that would be equally and openly accessible to all individuals and organizations interested in contributing efforts towards volunteer/service experiences. The platform will implement a filtering system that would categorize service opportunities and events based on personal preferences and interests, thus enabling a more efficient and effective method of discovering various opportunities that an individual would be passionate in contributing their efforts towards. Our platform would also implement a community based aspect that fosters further communication and interactions amongst volunteers as well as organizations involved in volunteer/service experiences.

ContributorsSalahuddin, Ibtesam (Author) / Murshed, Faiyaj (Co-author) / Byrne, Jared (Thesis director) / Surmacz, Amaris (Committee member) / Young, Andrea (Committee member) / Barrett, The Honors College (Contributor) / Department of Psychology (Contributor) / School of Life Sciences (Contributor)
Created2023-05
Description

Baked by Barrett facilitates the collection, review, and sale of home-baked goods through various means weekly. This will include, while not limited to, hosting tabling and social events throughout the academic year. This user-led platform will share the proceeds with bakers, and local charities of choice while maintaining a percentage

Baked by Barrett facilitates the collection, review, and sale of home-baked goods through various means weekly. This will include, while not limited to, hosting tabling and social events throughout the academic year. This user-led platform will share the proceeds with bakers, and local charities of choice while maintaining a percentage internally to ensure efficient operations. Because businesses for profit are a conflict of interest for ASU, the organization will work to promote students and charity along with the learning for business and entrepreneurial ventures. Instead of generating profits, Baked by Barrett will focus on sustaining itself while the rest of the revenue will go to charity. This will help the organization avoid conflicts of interest with ASU allowing it to use campus space to sell. Marketing will, initially, be based on word-of-mouth, with supporting tools including a dynamic website, flyers, and partnerships around local newsletters. Rotations of charities and menu items will be used to incentivize students and passersby to buy from Baked by Barrett. In order to promote the organization, there will be a website, flyers, and even contact information through the Barrett digest to market the platform in the weekly newsletter.

ContributorsShrader, Mikayla (Author) / Simon, Macy (Co-author) / Hamel, Pierre (Co-author) / Lopez, Ludwig (Co-author) / Byrne, Jared (Thesis director) / Balven, Rachel (Committee member) / Thirunagari, Samay (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor)
Created2023-05
Description

For the honors thesis project, a group of five individuals collaborated to design and implement a sustainable business in the ASU community. Kandi Society is a rising jewelry brand whose top priorities include giving recycled plastic a new purpose, philanthropy, and making a welcoming, creative environment for our customers. We

For the honors thesis project, a group of five individuals collaborated to design and implement a sustainable business in the ASU community. Kandi Society is a rising jewelry brand whose top priorities include giving recycled plastic a new purpose, philanthropy, and making a welcoming, creative environment for our customers. We designed the Eco-Bead with 3D CAD modeling and produced it through a process called plastic injection molding which is explained in detail in the final paper. Kandi Society instilled a positive impact on ASU students by igniting a sustainability spark and increasing interest in repurposing materials in the future.

ContributorsMaxwell, Olivia (Author) / Connoly, Payton (Co-author) / Guebara, Chloe (Co-author) / Grundhoffer, Andie (Co-author) / Bia, Aleya (Co-author) / Bryne, Jared (Thesis director) / Swader, Melissa (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor) / Dean, W.P. Carey School of Business (Contributor)
Created2023-05
Description

Our bodies are constantly fighting off viral pathogens both with our external barriers such as skin as well as internally through the immune system. Mucin genes specifically Muc5AC and Muc5B help assist in this process by activating both bacterial and mucus pathogenesis. Their gene expression is correlated with temperature meaning

Our bodies are constantly fighting off viral pathogens both with our external barriers such as skin as well as internally through the immune system. Mucin genes specifically Muc5AC and Muc5B help assist in this process by activating both bacterial and mucus pathogenesis. Their gene expression is correlated with temperature meaning that in warmer temperatures they have decreased expression. Developing a better understanding of their functionality as well as their expression can help species that are in danger of becoming extinct.

ContributorsWang, Dylan (Author) / Kusumi, Kenro (Thesis director) / Benson, Derek (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor) / Dean, W.P. Carey School of Business (Contributor) / Department of Finance (Contributor)
Created2023-05