Barrett, The Honors College at Arizona State University proudly showcases the work of undergraduate honors students by sharing this collection exclusively with the ASU community.

Barrett accepts high performing, academically engaged undergraduate students and works with them in collaboration with all of the other academic units at Arizona State University. All Barrett students complete a thesis or creative project which is an opportunity to explore an intellectual interest and produce an original piece of scholarly research. The thesis or creative project is supervised and defended in front of a faculty committee. Students are able to engage with professors who are nationally recognized in their fields and committed to working with honors students. Completing a Barrett thesis or creative project is an opportunity for undergraduate honors students to contribute to the ASU academic community in a meaningful way.

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ContributorsPascetti, Sarah (Author) / Hedges, Craig (Thesis director) / Fischer, Heidi (Committee member) / Trujillo, Rhett (Committee member) / Barrett, The Honors College (Contributor) / Dean, W.P. Carey School of Business (Contributor) / College of Health Solutions (Contributor) / Industrial, Systems & Operations Engineering Prgm (Contributor)
Created2023-05
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ContributorsPascetti, Sarah (Author) / Hedges, Craig (Thesis director) / Fischer, Heidi (Committee member) / Trujillo, Rhett (Committee member) / Barrett, The Honors College (Contributor) / Dean, W.P. Carey School of Business (Contributor) / College of Health Solutions (Contributor) / Industrial, Systems & Operations Engineering Prgm (Contributor)
Created2023-05
Description
For my thesis, I researched the impact of the gut microbiome on people's lives. My thesis paper explains what the microbiome is, the microbiome-gut-brain axis, the effect of the standard American diet on the human microbiome, and why children might be the solution to fostering a more healthy and happy

For my thesis, I researched the impact of the gut microbiome on people's lives. My thesis paper explains what the microbiome is, the microbiome-gut-brain axis, the effect of the standard American diet on the human microbiome, and why children might be the solution to fostering a more healthy and happy America. There is a direct connection between one's gut health and one's overall health and happiness. Since the microbiome influences many aspects of people's lives, it is important to take care of it and always protect it. Everything that people consume and expose themselves to will either enhance or destroy the gut microbiome. By bringing awareness of the importance of the gut microbiome to the general population and by providing better resources for Americans to cultivate a healthy microbiome, then more Americans will experience an overall greater quality of life.
ContributorsPascetti, Sarah (Author) / Hedges, Craig (Thesis director) / Fischer, Heidi (Committee member) / Trujillo, Rhett (Committee member) / Barrett, The Honors College (Contributor) / Dean, W.P. Carey School of Business (Contributor) / College of Health Solutions (Contributor) / Industrial, Systems & Operations Engineering Prgm (Contributor)
Created2023-05
Description
Autism Spectrum Disorder (ASD) is an intricate neurodevelopmental disorder characterized by impaired social functioning and communication, repetitive behavioral patterns, and specialized interests (Olesova et al., 2020; Osredkar et al., 2023). Despite the efforts of modern science, the biological origin of ASD is unknown, and no known biomarker for ASD currently

Autism Spectrum Disorder (ASD) is an intricate neurodevelopmental disorder characterized by impaired social functioning and communication, repetitive behavioral patterns, and specialized interests (Olesova et al., 2020; Osredkar et al., 2023). Despite the efforts of modern science, the biological origin of ASD is unknown, and no known biomarker for ASD currently exists (Olesova et al., 2020; Osredkar et al., 2023). Indoxyl sulfate has been identified as a toxin associated with ASD and its related symptomology in addition to a number of other conditions, including chronic kidney disease, acute kidney injury, heart failure, Parkinson’s disease, and various mood disorders (Cao et al., 2015; Cassani et al., 2015; Karbowska et al., 2020; Zhao et al., 2013). This article will review what is currently known about indoxyl sulfate in relation to ASD and its comorbidities in an attempt to determine the validity of indoxyl sulfate as a potential biomarker for ASD. Articles for the purposes of this review were collected via Google Scholar, PubMed, and the ASU Library using key words such as “indoxyl sulfate,” “Autism,” and “indican,” and chosen based on relevancy. Through this review, indoxyl sulfate was identified as a potential physiological biomarker for a subset of ASD, with additional research required to verify the findings presented. The identification of a biomarker for ASD could change the current methods of testing for ASD, greatly improving our understanding and treatment of the disorder.
ContributorsHill, Zoë (Author) / Adams, James (Thesis director) / Flynn, Christina (Committee member) / Barrett, The Honors College (Contributor) / College of Health Solutions (Contributor) / Edson College of Nursing and Health Innovation (Contributor)
Created2024-05