Barrett, The Honors College at Arizona State University proudly showcases the work of undergraduate honors students by sharing this collection exclusively with the ASU community.

Barrett accepts high performing, academically engaged undergraduate students and works with them in collaboration with all of the other academic units at Arizona State University. All Barrett students complete a thesis or creative project which is an opportunity to explore an intellectual interest and produce an original piece of scholarly research. The thesis or creative project is supervised and defended in front of a faculty committee. Students are able to engage with professors who are nationally recognized in their fields and committed to working with honors students. Completing a Barrett thesis or creative project is an opportunity for undergraduate honors students to contribute to the ASU academic community in a meaningful way.

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With millions of people living with a disease as restraining as migraines, there are no ways to diagnose them before they occur. In this study, a migraine model using nitroglycerin is used in rats to study the awake brain activity during the migraine state. In an attempt to search for

With millions of people living with a disease as restraining as migraines, there are no ways to diagnose them before they occur. In this study, a migraine model using nitroglycerin is used in rats to study the awake brain activity during the migraine state. In an attempt to search for a biomarker for the migraine state, we found multiple deviations in EEG brain activity across different bands. Firstly, there was a clear decrease in power in the delta, beta, alpha, and theta bands. A slight increase in power in the gamma and high frequency bands was also found, which is consistent with other pain-related studies12. Additionally, we searched for a decreased pain threshold in this deviation, in which we concluded that more data analysis is needed to eliminate the multiple potential noise influxes throughout each dataset. However, with this study we did find a clear change in brain activity, but a more detailed analysis will narrow down what this change could mean and how it impacts the migraine state.

ContributorsStrambi, McKenna (Author) / Muthuswamy, Jitendran (Thesis director) / Greger, Bradley (Committee member) / Barrett, The Honors College (Contributor) / Harrington Bioengineering Program (Contributor)
Created2023-05