Barrett, The Honors College Thesis/Creative Project Collection
Barrett, The Honors College at Arizona State University proudly showcases the work of undergraduate honors students by sharing this collection exclusively with the ASU community.
Barrett accepts high performing, academically engaged undergraduate students and works with them in collaboration with all of the other academic units at Arizona State University. All Barrett students complete a thesis or creative project which is an opportunity to explore an intellectual interest and produce an original piece of scholarly research. The thesis or creative project is supervised and defended in front of a faculty committee. Students are able to engage with professors who are nationally recognized in their fields and committed to working with honors students. Completing a Barrett thesis or creative project is an opportunity for undergraduate honors students to contribute to the ASU academic community in a meaningful way.
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- All Subjects: Memory
- Creators: Corbin, William
Description
Familiar Places: Ghosts of a Memory is a thesis exhibition, presented in Gallery 100 in Tempe, AZ, accompanied by a written investigation into the function of photography in the home and art. This project is a diaristic photographic record including images of myself, my family, my environment, and mementos or objects that embody family history. I am interested in what we hold onto to keep memories and create our "home". I moved frequently growing up so my sense of home became firmly grounded in family, tradition, and the things we kept close, making home a practiced space not a place. This thesis project explores how material culture, including photographs, is used in creating the space of the home. Questions regarding the nature of the photograph as a memory keeping device or memory trigger is investigated to understand their usefulness and accuracy to the memory. A deeper examination of the difference between an artist's photograph of family and home versus the family photograph is discussed and presented by utilizing installations in the exhibition. The photographs can be seen at www.gwendolynanne.com
ContributorsDavies, Gwendolyn Anne (Author) / Smith, Stephen Mark (Thesis director) / Danh, Binh (Committee member) / Loebenberg, Abby (Committee member) / School of Art (Contributor) / Barrett, The Honors College (Contributor)
Created2015-12
Description
It is well documented that menopause and the related decline in circulatory steroid hormones estrogen and progesterone are associated with memory alterations. Rodent models of surgical menopause can be used to study these effects, including ovariectomy (Ovx), or the surgical removal of the ovaries. This thesis aimed to characterize the effects of surgical menopause on spatial working and reference memory in rats and examine profiles of uterine gene expression alterations that may serve as indications of mechanisms underlying this association. Eighteen female rats were randomly assigned to one of two surgical treatment groups, either Ovx (the surgical menopause group) or sham (the control group). All subjects underwent testing on the water version of the radial arm maze (WRAM) which allows for the assessment of reference memory errors and two types of working memory errors. After behavioral testing, rat uterine tissues were dissected and RNA sequenced. The results showed that Ovx impaired spatial reference memory performance during a maze learning phase, with Ovx rats making reference memory failures earlier in the day, even before working memory load increased, as compared to control rats. There were no surgical menopause effects on spatial working memory, which may be due to the low working memory load and the young age of the rats. Post-hoc analyses showed that reference memory performance was correlated with nerve growth factor (NGF) and acetylcholinesterase (AChE) gene expression in uterine tissues. These findings add to the literature on the impact of estrogen and female cyclicity on memory and cognition. The results suggest that Ovx impairment of the ability to learn long-term spatial memory information relates to uterine gene expression underlying cellular functioning and that NGF and AChE genes are involved in pathways that give way to underlying cellular functioning that impacts cognition. Future studies should continue to evaluate the effects of menopause on memory function and the effectiveness of hormone therapy.
ContributorsOyen, Emma (Author) / Bimonte-Nelson, Heather (Thesis director) / Corbin, William (Committee member) / Wilson, Melissa (Committee member) / Lizik, Camryn (Committee member) / Barrett, The Honors College (Contributor) / Department of Psychology (Contributor)
Created2024-05