Barrett, The Honors College Thesis/Creative Project Collection
Barrett, The Honors College at Arizona State University proudly showcases the work of undergraduate honors students by sharing this collection exclusively with the ASU community.
Barrett accepts high performing, academically engaged undergraduate students and works with them in collaboration with all of the other academic units at Arizona State University. All Barrett students complete a thesis or creative project which is an opportunity to explore an intellectual interest and produce an original piece of scholarly research. The thesis or creative project is supervised and defended in front of a faculty committee. Students are able to engage with professors who are nationally recognized in their fields and committed to working with honors students. Completing a Barrett thesis or creative project is an opportunity for undergraduate honors students to contribute to the ASU academic community in a meaningful way.
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- All Subjects: Neuroscience
Description
This research looks at the state of Anglo-American political relations since 1980. By examining the political partnerships between Ronald Reagan and Margaret Thatcher, Margaret Thatcher and George H.W. Bush, George W. Bush and Tony Blair, Barack Obama and Gordon Brown, and Barack Obama and David Cameron, it explores if the so called ‘special relationship’ remains so special today in a world of growing political animosity and challenges. The thesis argues that the success of the ‘special relationship’ between the United States and United Kingdom has not been just due to similar political ideologies or goals, but also personal friendships which often overcame national interests or immediate personal political gain. Furthermore, it is often the periods of disagreement between these sets of leaders that helped strengthen the relationship between America and Britain, evidenced by episodes like the Falklands War, policy towards the Soviet Union, the invasion of Grenada, and the wars in Iraq and Afghanistan. Ultimately, the thesis explores how current relations have deteriorated due to problems on both sides of the Atlantic under the Obama, Brown, and Cameron administrations, but the research concludes that the special relationship is, while damaged, alive and fixable.
ContributorsGavin, Stephen Christopher (Author) / Critchlow, Donald (Thesis director) / Stermetz, Catherine (Committee member) / School of Politics and Global Studies (Contributor) / School of Historical, Philosophical and Religious Studies (Contributor) / Barrett, The Honors College (Contributor)
Created2015-12
Description
Scientists, lawyers, and bioethicists have pondered the impact of scientifically deterministic evidence on a judge or jury when deciding the sentence of a criminal. Though the impact may be one that relieves the amount of personal guilt on the part of the criminal, this evidence may also be the very reason that a judge or jury punishes more strongly, suggesting that this type of evidence may be a double-edged sword. 118 participants were shown three films of fictional sentencing hearings. All three films introduced scientifically deterministic evidence, and participants were asked to recommend a prison sentence. Each hearing portrayed a different criminal with different neurological conditions, a different crime, and a different extent of argumentation during closing arguments about the scientifically deterministic evidence. Though the argumentation from the prosecution and the defense did not affect sentencing, the interaction of type of crime and neurological condition did.
ContributorsMeschkow, Alisha Sadie (Author) / Schweitzer, Nicholas (Thesis director) / Robert, Jason (Committee member) / Patten, K. Jakob (Committee member) / Barrett, The Honors College (Contributor) / Department of Psychology (Contributor)
Created2014-05
Description
Substance abuse disorders affect 15.3 million people worldwide. The field has primarily focused on dopaminergic drugs as treatments for substance use disorders. However, recent work has demonstrated the potential of serotonergic compounds to treat substance abuse. Specifically, the serotonin 1B receptor (5-HT1BR), a Gi-coupled receptor located throughout the mesocorticolimbic dopamine system, has been implicated in the incentive motivational and rewarding effects of cocaine. Our research suggests that the stimulation of 5-HT1BRs produces different effects at various time points in the addiction cycle. During maintenance of chronic cocaine administration, 5-HT1BR stimulation has a facilitative effect on the reinforcing properties of cocaine. However 5-HT1BR stimulation exhibits inhibitory effects on reinforcement during prolonged abstinence from cocaine. The aim of this study was to examine the possibility of a switch in the functional role of 5-HT1BRs in the locomotor effects of cocaine at different time points of chronic cocaine administration in mice. We found that the 5-HT1BR agonist CP 94,253 increased locomotor activity in mice tested one day after the last chronic cocaine administration session regardless of whether the chronic treatment was cocaine or saline and regardless of challenge injection (i.e., cocaine or saline). Yet after abstinence, CP 94,253 induced a decrease in locomotor activity in mice challenged with saline and attenuated cocaine-induced locomotion relative to cocaine challenge after vehicle pretreatment. These findings suggest that a switch in the functional role of 5-HT1BR is observed at different stages of the addiction cycle and further suggest that clinical applications of drugs acting on 5-HT1BR should consider these effects.
ContributorsBrunwasser, Samuel Joshua (Author) / Neisewander, Janet (Thesis director) / Pentkowski, Nathan (Committee member) / Der-Ghazarian, Taleen (Committee member) / Barrett, The Honors College (Contributor) / Department of Chemistry and Biochemistry (Contributor) / Department of Psychology (Contributor)
Created2014-05
Description
A study on the effectiveness of different graphic design elements, such as color and shape, in political communication over a digital medium. The study was conducted through an online survey of young adults (18-25 years old). Participants' preferences for the design elements are compared to their online and offline political participation and their primary sources for political information.
ContributorsRyan, Daiquiri Ice (Author) / Lennon, Tara (Thesis director) / Woodall, Gina (Committee member) / Blyler, Lisa (Committee member) / Barrett, The Honors College (Contributor) / Walter Cronkite School of Journalism and Mass Communication (Contributor) / School of Politics and Global Studies (Contributor)
Created2014-05
ContributorsSavarese, Erica (Author) / Robert, Jason (Thesis director) / Hurlbut, Ben (Committee member) / Verrelli, Brian (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor)
Created2013-05
Description
An analysis of recent historical trends demonstrates that, while a large part of the twentieth century was dominated by a secular movement away from faith-based governance and societal norms, there exists now in the twenty-first century a developing global movement on the part of a burgeoning, international religious community to again find and clarify a place for faith in the public square. While much of the current international conversation revolves around the more radical elements of this movement, there is a more dominant mainstream, rational desire that is currently being overlooked and ignored, as modern, secular nation-states now grapple to balance freedom of religion and expression with a perceived constitutional and legal mandate to remain secular and neutral. This thesis will provide a study of the Republic of Kosovo as an example of such a conflict between the secular state and religious communities, highlighting its shift towards secularism, observing the religious community in Kosovo advocating for religious freedoms and a presence in the public sphere, and analyzing case law and social theory surrounding recent confrontations between this community and Kosovo's government and legal structure at large. The conclusion of this investigation will establish Kosovo as a local case study with global application, arguing that a misunderstanding of secularism to mean the crowding out of religion from the public sphere is an unsustainable approach for modern governments to take, and prescribing a model for equal representation and civil society that provides religious communities with opportunities to translate their values into more normative societal language with broad application.
ContributorsYentzer, Zachary Thomas (Author) / Batalden, Stephen (Thesis director) / Kader, David (Committee member) / Berisha, Shahin (Committee member) / Barrett, The Honors College (Contributor) / School of Politics and Global Studies (Contributor)
Created2013-05
Description
The role of retention and forgetting of context dependent sensorimotor memory of dexterous manipulation was explored. Human subjects manipulated a U-shaped object by switching the handle to be grasped (context) three times, and then came back two weeks later to lift the same object in the opposite context relative to that experience on the last block. On each context switch, an interference of the previous block of trials was found resulting in manipulation errors (object tilt). However, no significant re-learning was found two weeks later for the first block of trials (p = 0.826), indicating that the previously observed interference among contexts lasted a very short time. Interestingly, upon switching to the other context, sensorimotor memories again interfered with visually-based planning. This means that the memory of lifting in the first context somehow blocked the memory of lifting in the second context. In addition, the performance in the first trial two weeks later and the previous trial of the same context were not significantly different (p = 0.159). This means that subjects are able to retain long-term sensorimotor memories. Lastly, the last four trials in which subjects switched contexts were not significantly different from each other (p = 0.334). This means that the interference from sensorimotor memories of lifting in opposite contexts was weaker, thus eventually leading to the attainment of steady performance.
ContributorsGaw, Nathan Benjamin (Author) / Santello, Marco (Thesis director) / Helms Tillery, Stephen (Committee member) / Buneo, Christopher (Committee member) / Barrett, The Honors College (Contributor) / School of Mathematical and Statistical Sciences (Contributor) / Harrington Bioengineering Program (Contributor)
Created2013-05
Description
Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a devastating illness that causes the degeneration of both upper and lower motor neurons, leading to eventual muscle atrophy. ALS rapidly progresses into paralysis, with patients typically dying due to respiratory complications within three to five years from the onset of their symptoms. Even after many years of research and drug trials, there is still no cure, and current therapies only succeed in increasing life-span by approximately three months. With such limited options available for patients, there is a pressing need to not only find a cure, but also make new treatments available in order to ameliorate disease symptoms. In a genome-wide association study previously conducted by the Translational Genomics Research Institute (TGen), several single-nucleotide polymorphisms (SNPs) upstream of a novel gene, FLJ10968, were found to significantly alter risk for ALS. This novel gene acquired the name FGGY after publication of the paper. FGGY exhibits altered levels of protein expression throughout ALS disease progression in human subjects, and detectable protein and mRNA expression changes in a mouse model of ALS. We performed co-immunoprecipitation experiments coupled with mass spectrometry in order to determine which proteins are associated with FGGY. Some of these potential binding partners have been linked to RNA regulation, including regulators of the splicesomal complex such as SMN, Gemin, and hnRNP C. To further validate these findings, we have verified co-localization of these proteins with one another. We hypothesize that FGGY plays an important role in ALS pathogenesis, and we will continue to examine its biological function.
ContributorsTerzic, Barbara (Author) / Jensen, Kendall (Thesis director) / Francisco, Wilson (Committee member) / Barrett, The Honors College (Contributor) / School of Mathematical and Statistical Sciences (Contributor) / Department of Chemistry and Biochemistry (Contributor) / School of Life Sciences (Contributor)
Created2014-05
Description
We were interested in whether or not certain demographics, such as gender, age, education level, and academic major, would affect an individual's political awareness. In particular, we hypothesized that Political Science majors would have a higher level of political awareness than Non-Political Science majors. In an in-person survey, we asked participants on the Arizona State University, Tempe campus a series of nine questions measuring government structure and procedure, current politics, and policy issues. Our findings concluded that, within our sample: 1) on average, Political Science majors outperformed Non-Political Science majors 2) education level appears to be positively associated with political awareness 3) like education, age appears to be positively associated with political awareness, however, there seemed to be a peak at 21 years of age 4) males outperformed females, as suggested by research studying the gender gap in political knowledge. Because our sample population was not randomly selected, and this report focuses on descriptive statistics, we cannot generalize or comment on our findings' statistical significance. However, many of our findings are supported by current research and, with further specification, may be of interest to university officials who seek to measure the political knowledge and awareness of various demographic groups on campus.
ContributorsTaylor, Kaela (Co-author) / Leung, Emily (Co-author) / Lennon, Tara (Thesis director) / Woodall, Gina (Committee member) / Barrett, The Honors College (Contributor) / W. P. Carey School of Business (Contributor) / School of International Letters and Cultures (Contributor) / School of Politics and Global Studies (Contributor) / Department of Information Systems (Contributor) / School of Accountancy (Contributor)
Created2014-05
Description
An introduction to neuroscientific thought aimed at an audience that is not educated in biology. Meant to be readable and easily understood by anyone with a high school education. The first section is completed in its entirety, with outlines for the proposed final sections to be completed over the next few years.
ContributorsNelson, Nicholas Alan (Author) / Olive, M. Foster (Thesis director) / Brewer, Gene (Committee member) / Barrett, The Honors College (Contributor) / Department of Psychology (Contributor) / School of Life Sciences (Contributor) / School of Historical, Philosophical and Religious Studies (Contributor)
Created2014-05