Barrett, The Honors College Thesis/Creative Project Collection
Barrett, The Honors College at Arizona State University proudly showcases the work of undergraduate honors students by sharing this collection exclusively with the ASU community.
Barrett accepts high performing, academically engaged undergraduate students and works with them in collaboration with all of the other academic units at Arizona State University. All Barrett students complete a thesis or creative project which is an opportunity to explore an intellectual interest and produce an original piece of scholarly research. The thesis or creative project is supervised and defended in front of a faculty committee. Students are able to engage with professors who are nationally recognized in their fields and committed to working with honors students. Completing a Barrett thesis or creative project is an opportunity for undergraduate honors students to contribute to the ASU academic community in a meaningful way.
Displaying 1 - 4 of 4
Description
Malignant Pleural Mesothelioma is a type of lung cancer usually discovered at an advanced stage at which point there is no cure. Six primary MPM cell lines were used to conduct in vitro research to make conclusions about specific gene mutations associated with Mesothelioma. DNA exome sequencing, a time efficient and inexpensive technique, was used for identifying specific DNA mutations. Computational analysis of exome sequencing data was used to make conclusions about copy number variation among common MPM genes. Results show a CDKN2A gene heterozygous deletion in Meso24 cell line. This data is validated by a previous CRISPR-Cas9 outgrowth screen for Meso24 where the knocked-out gene caused increased Meso24 growth.
ContributorsKrdi, Ghena (Author) / Plaisier, Christopher (Thesis director) / Wilson, Melissa (Committee member) / School of Life Sciences (Contributor) / Hugh Downs School of Human Communication (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
Physical therapy patients still receive their plan of care onto a piece of paper when there are hundreds of engaging physical therapy exercise videos on the internet. These exercise videos are way more appealing to watch and physical therapists should consider delivering Home Exercise Programs (HEP) digitally. There are apps and online services such as Physioadvisor, Physprac app, Anterior Cruciate Ligament repair app, and work-out apps for people to create their own plan of care and are easily accessible with any electronic device. Most people are receiving information and learning through a lit screen anyways so it may only be a matter of time before people start using these resources instead of a physical therapist. Physical Therapists need to provide better resources for their patients and an app may be all they need. Figures of the results of the Qualtrics survey both Physical Therapists and Patient responses and were provided. A data analysis of each question and responses were interpreted to determine whether patients and physical therapists would like to use a physical therapy app as part of their rehab program. A Physiotherapy research journal with Switzerland researchers conducted a case study in a hospital and determined whether a HEP app testing was effective for patients to utilize.
ContributorsChang, Cheng H. (Author) / Holzapfel, Simon (Thesis director) / Peterson, Daniel (Committee member) / College of Health Solutions (Contributor, Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
The purpose of this paper is to explore and minimum wage and whether it serves its purpose of fighting poverty. After extensive research on the origin and purpose of minimum wage laws in the US via reading different studies and weighing its positive and negative effects, I have found that minimum wage is not the most effective tool to fight poverty. There exist programs that would be more beneficial in fighting poverty such as earned-income tax credit (EITC) or training programs.
ContributorsHarvey, Vanessa Nicole (Author) / Douglas, Kacey (Thesis director, Committee member) / School of International Letters and Cultures (Contributor) / Department of Information Systems (Contributor) / Department of Economics (Contributor) / Dean, W.P. Carey School of Business (Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
Pathway analysis helps researchers gain insight into the biology behind gene expression-based data. By applying this data to known biological pathways, we can learn about mutations or other changes in cellular function, such as those seen in cancer. There are many tools that can be used to analyze pathways; however, it can be difficult to find and learn about the which tool is optimal for use in a certain experiment. This thesis aims to comprehensively review four tools, Cytoscape, PaxtoolsR, PathOlogist, and Reactome, and their role in pathway analysis. This is done by applying a known microarray data set to each tool and testing their different functions. The functions of these programs will then be analyzed to determine their roles in learning about biology and assisting new researchers with their experiments. It was found that each tools holds a very unique and important role in pathway analysis. Visualization pathways have the role of exploring individual pathways and interpreting genomic results. Quantification pathways use statistical tests to determine pathway significance. Together one can find pathways of interest and then explore areas of interest.
ContributorsRehling, Thomas Evan (Author) / Buetow, Kenneth (Thesis director) / Wilson, Melissa (Committee member) / School of Life Sciences (Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2020-05