Barrett, The Honors College Thesis/Creative Project Collection
Barrett, The Honors College at Arizona State University proudly showcases the work of undergraduate honors students by sharing this collection exclusively with the ASU community.
Barrett accepts high performing, academically engaged undergraduate students and works with them in collaboration with all of the other academic units at Arizona State University. All Barrett students complete a thesis or creative project which is an opportunity to explore an intellectual interest and produce an original piece of scholarly research. The thesis or creative project is supervised and defended in front of a faculty committee. Students are able to engage with professors who are nationally recognized in their fields and committed to working with honors students. Completing a Barrett thesis or creative project is an opportunity for undergraduate honors students to contribute to the ASU academic community in a meaningful way.
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Description
Engineering is a heavily male-dominated field and females are significantly less likely to choose an engineering-related major or career path. At the age of six years old, females start believing that their male peers are smarter than them, leading them to pursue less ambitious careers. The children's book Lyla B. An Engineering Legacy was created to encourage more young girls to discover their own potential and pursue engineering as a career. To explore the efficacy of the book on its target consumers, a pilot study was performed with first and second grade children. The participants' engineering knowledge; fixed and failure mindset beliefs; STEM (Science, Technology, Engineering, and Math) interest, competency, and career aspirations; and stereotype beliefs were evaluated before and after being read the book to determine if the story has a positive impact on children. Additionally, the satisfaction of the participants towards both the book and main character were analyzed quantitatively and qualitatively. Overall, the results of the study suggest that the book has a positive impact on the interest and competency of STEM fields and the stereotype beliefs that the children had towards engineers. The study also suggests that the book decreases fixed and failure mindsets and that the participants were satisfied with the overall concept of the book and main character, Lyla.
ContributorsPiatak, Catherine (Co-author) / Seelhammer, Marissa Leigh (Co-author) / Torrence, Kelly (Co-author) / Miller, Cindy (Thesis director) / Jordan, Shawn (Committee member) / Harrington Bioengineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
Gendered products are prevalent in the modern consumer products market. This paper provides historical context for the change in the consumer products market which started as a genderless product market and shifted to a female consumer-centric market reflecting the economic needs of the United States through World War I and II. This female consumer-centric market results from the rise of consumer research and many household products are created to satisfy female consumer preferences. But as the consumer demographics change with more women entering the labor force, the types of products being sold change to appeal to the increasing number of male consumers who begin shopping for themselves. This increase in male products is what leads to the booming men's personal care products market that we see today. With an increase in gendered products, there has also been an increase in the number of backlash companies face for creating specific gendered products. This paper outlines the history of gendered products and the potential future of products in the United States.
ContributorsLavergne, Lisa (Author) / Foster, William (Thesis director) / Goegan, Brian (Committee member) / Economics Program in CLAS (Contributor) / The Design School (Contributor) / Herberger Institute for Design and the Arts (Contributor) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
This thesis explores the framing of gender equity within International Development organizations and the design of projects to promote it. Using case studies of projects financed by United States Agency for International Development (a major donor agency), and Inter Pares (a Canadian NGO) as evidence, the thesis identifies what works and what does not work in different contexts within these projects.
ContributorsPetersen, Melia Bea (Author) / Aggarwal, Rimjhim (Thesis director) / Manuel-Navarette, David (Committee member) / School of Politics and Global Studies (Contributor) / School of International Letters and Cultures (Contributor) / School of Sustainability (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
Prior expectations can bias evaluative judgments of sensory information. We show that information about a performer's status can bias the evaluation of musical stimuli, reflected by differential activity of the ventromedial prefrontal cortex (vmPFC). Moreover, we demonstrate that decreased susceptibility to this confirmation bias is (a) accompanied by the recruitment of and (b) correlated with the white-matter structure of the executive control network, particularly related to the dorsolateral prefrontal cortex (dlPFC). By using long-duration musical stimuli, we were able to track the initial biasing, subsequent perception, and ultimate evaluation of the stimuli, examining the full evolution of these biases over time. Our findings confirm the persistence of confirmation bias effects even when ample opportunity exists to gather information about true stimulus quality, and underline the importance of executive control in reducing bias.
ContributorsAydogan, Goekhan (Co-author, Committee member) / Flaig, Nicole (Co-author) / Larg, Edward W. (Co-author) / Margulis, Elizabeth Hellmuth (Co-author) / McClure, Samuel (Co-author, Thesis director) / Nagishetty Ravi, Srekar Krishna (Co-author) / Harrington Bioengineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
Globally, suicide is the second leading cause of death, and accounts for about 800,000 deaths per year worldwide (WHO, 2013). The majority of these deaths occur in low and middle-income countries (LMIC), yet the research and documentation of suicide is heavily skewed to higher income countries where more systematic reporting of suicide occurs, along with a larger existing evidence base. Nepal is one LMIC where the speculated burden of suicide is high, with a predicted suicide rate of 7th highest in the world. Using both public-health and ethnographic approaches, the current study contributes to the discussion about suicide in Nepal. The primary goal of this research study is to understand the similarities and differences in perceived drivers for suicide for men and women in Nepal. Interviews conducted in Kathmandu and Jumla, Nepal were transcribed, and free lists which described drivers for suicide for men and women were extracted from the narratives. Thematic codes were then created to classify narrative responses into a cultural domain. The most salient codes listed by males and females for drivers for male/female suicide were analyzed and further contextualized using interview dialogue. Findings reveal social and relational drivers of suicide as the most salient for both genders, suggesting that suicide is not an individual act, but something that is caused by the broader, social environment. Additionally, perceptions of the reasons for suicide vary between gender. Perceived drivers for suicide for males are more often correlated with financial burden and the responsibilities tied to being the source of income and prosperity in a highly patriarchal society. Violence and inequality are perceived to be among the main drivers for female suicide. Findings contribute to the ethnographic research of suicide and the suicide literature in Nepal, and generate a better understanding of how reasons for suicide differ among males and females.
ContributorsFarrier, Brianna (Author) / Maupin, Jonathan (Thesis director) / Hagaman, Ashley (Committee member) / Barrett, The Honors College (Contributor)
Created2018-05
Description
The purpose of this paper is to investigate the role of socialization in observed gender differences in emotional regulation. Drawing on a wide range of research regarding emotion, emotional regulation, and socialization, it is evident that the way in which boys and girls are taught to handle their emotions is not the same. Parents typically utilize an emotion-coaching philosophy with their daughters, and an emotion-dismissing philosophy with their sons, which may have detrimental consequences for the emotional regulation of boys and men. It is likely that gender differences in the socialization of emotional regulation stem from deeply rooted gender-emotion stereotypes within Western cultures. These gender-emotion stereotypes yield negative consequences in both the lives of men and women and are still to this day being reinforced by emotion socialization. This paper has implications for parents, teachers, therapists, and other individuals or professionals dealing with students, children, men, or women struggling with or learning about emotion.
ContributorsGriffin, Montana (Author) / Swanson, Jodi (Thesis director) / Scott Lynch, Jacquelyn (Committee member) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
Egr3 is an immediate early gene transcription factor that shows genetic association with schizophrenia, and is found in decreased levels in the brains of schizophrenia patients. Schizophrenia patients also exhibit cognitive and memory deficits, both of which Egr3 has been shown to play a crucial role in. Additionally, high levels of DNA damage are found in the brains of schizophrenia patients. A recent study has shown that DNA damage occurs as a result of normal physiological activity in neurons and is required for induction of gene expression of a subset of early response genes. Also, failure to repair this damage can lead to gene expression in a constitutive switched on state. Egr3 knockout (Egr3-/-) mice show deficits in hippocampal synaptic plasticity and memory. We were interested in characterizing downstream targets of EGR3 in the hippocampus. To determine these targets, electroconvulsive seizure (ECS) was carried out in Egr3 -/- versus wild type (WT) mice, and a microarray study was first done in our lab. ECS maximally stimulates Egr3 expression and we hypothesized that there would be gene targets that are differentially expressed between Egr3 -/- and WT mice that had been subjected to ECS. Two separate analyses of the microarray yielded 65 common genes that were determined as being differentially expressed between WT and Egr3 -/- mice after ECS. Further Ingenuity Pathway Analysis of these 65 genes indicated the Gadd45 signaling pathway to be the top canonical pathway, with the top four pathways all being associated with DNA damage or DNA repair. A literature survey was conducted for these 65 genes and their associated pathways, and 12 of the 65 genes were found to be involved in DNA damage response and/or DNA repair. Validation of differential expression was then conducted for each of the 12 genes, in both the original male cohort used for microarray studies and an additional female cohort of mice. 7 of these genes validated through quantitative real time PCR (qRT-PCR) in the original male cohort used for the microarray study, and 4 validated in both the original male cohort and an independent female cohort. Bioinformatics analysis yielded predicted EGR3 binding sites in promoters of these 12 genes, validating their role as potential transcription targets of EGR3. These data reveal EGR3 to be a novel regulator of DNA repair. Further studies will be needed to characterize the role of Egr3 in repairing DNA damage.
ContributorsBarkatullah, Arhem Fatima (Author) / Newbern, Jason (Thesis director) / Gallitano, Amelia (Committee member) / Marballi, Ketan (Committee member) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
The goal of my study is to test the overarching hypothesis that art therapy is effective because it targets emotional dysregulation that often accompanies significant health stressors. By reducing the salience of illness-related stressors, art therapy may improve overall mood and recovery, particularly in patients with cancer. After consulting the primary literature and review papers to develop psychological and neural mechanisms at work in art therapy, I created a hypothetical experimental procedure to test these hypotheses to explain why art therapy is helpful to patients with chronic illness. Studies found that art therapy stimulates activity of multiple brain regions involved in memory retrieval and the arousal of emotions. I hypothesize that patients with chronic illness have a reduced capacity for emotion regulation, or difficulty recognizing, expressing or altering illness-related emotions (Gross & Barrett, 2011). Further I hypothesize that art therapy improves mood and therapeutic outcomes by acting on the emotion-processing regions of the limbic system, and thereby facilitating the healthy expression of emotion, emotional processing, and reappraisal. More mechanistically, I propose art therapy reduces the perception or salience of stressors by reducing amygdala activity leading to decreased activation of the hypothalamic-pituitary-adrenal (HPA) axis. The art therapy literature and my hypothesis about its mechanisms of action became the basis of my proposed study. To assess the effectiveness of art therapy in alleviating symptoms of chronic disease, I am specifically targeting patients with cancer who exhibit a lack of emotional regulation. Saliva is collected 3 times a week on the day of intervention: morning after waking, afternoon, and evening. Stress levels are tested using one-hour art therapy sessions over the course of 3 months. The Perceived Stress Scale (PSS) assesses an individual's perceived stress and feelings in past and present situations, for the control and intervention group. To measure improvement in overall mood, 10 one-hour art sessions are performed on patients over 10 weeks. A one-hour discussion analyzing the participants' artwork follows each art session. The Spielberger State-Trait Anxiety Inventory (STAI) assesses overall mood for the intervention and control groups. I created rationale and predictions based on the intended results of each experiment.
ContributorsAluri, Bineetha C. (Author) / Orchinik, Miles (Thesis director) / Davis, Mary (Committee member) / Essary, Alison (Committee member) / School of Life Sciences (Contributor) / School for the Science of Health Care Delivery (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a devastating illness that causes the degeneration of both upper and lower motor neurons, leading to eventual muscle atrophy. ALS rapidly progresses into paralysis, with patients typically dying due to respiratory complications within three to five years from the onset of their symptoms. Even after many years of research and drug trials, there is still no cure, and current therapies only succeed in increasing life-span by approximately three months. With such limited options available for patients, there is a pressing need to not only find a cure, but also make new treatments available in order to ameliorate disease symptoms. In a genome-wide association study previously conducted by the Translational Genomics Research Institute (TGen), several single-nucleotide polymorphisms (SNPs) upstream of a novel gene, FLJ10968, were found to significantly alter risk for ALS. This novel gene acquired the name FGGY after publication of the paper. FGGY exhibits altered levels of protein expression throughout ALS disease progression in human subjects, and detectable protein and mRNA expression changes in a mouse model of ALS. We performed co-immunoprecipitation experiments coupled with mass spectrometry in order to determine which proteins are associated with FGGY. Some of these potential binding partners have been linked to RNA regulation, including regulators of the splicesomal complex such as SMN, Gemin, and hnRNP C. To further validate these findings, we have verified co-localization of these proteins with one another. We hypothesize that FGGY plays an important role in ALS pathogenesis, and we will continue to examine its biological function.
ContributorsTerzic, Barbara (Author) / Jensen, Kendall (Thesis director) / Francisco, Wilson (Committee member) / Barrett, The Honors College (Contributor) / School of Mathematical and Statistical Sciences (Contributor) / Department of Chemistry and Biochemistry (Contributor) / School of Life Sciences (Contributor)
Created2014-05
Description
Abstract Chronic pain is a growing problem in the western world and is one of the largest costs to the healthcare system. In order to decrease both the prevalence and the cost, it is necessary to understand factors that influence the chronic pain experience and potential ways to treat it. This literature review examines three demographic factors - gender, ethnicity and age \u2014 and the effect each has on the chronic pain experience. Pain intensity, disability caused by pain, mood and coping were reviewed in relation to gender. No conclusions were able to be drawn based on the literature reviewed for any of the topics; findings were conflicting. Ethnic groups with chronic pain were evaluated for differences in the pain experience, psychological and emotional responses and coping. A lack of consistent findings among studies made it hard to come to conclusions. As children and adolescents get older, the frequency of their pain becomes higher. The literature review then continues by examining three treatment methods: cognitive behavioral therapy, hypnosis and exercise. Each treatment method discussed had beneficial outcomes in the treatment of chronic pain. Cognitive behavioral therapy seemed to be the most beneficial both short- and long-term. Hypnosis was most beneficial short-term for flair-ups and exercise had the best effects long term when the treatment is continued. In the future, I recommend designing a study that takes into consideration multiple variables that may have an effect on the pain experience including gender, ethnicity, age, socioeconomic status, education, income and duration of pain, and manipulating one at a time.
ContributorsHarris, Ellaura Yvonne-True (Author) / Miller, Paul (Thesis director) / Newman, Matt (Committee member) / Barrett, The Honors College (Contributor) / School of Social and Behavioral Sciences (Contributor)
Created2014-05