Barrett, The Honors College Thesis/Creative Project Collection
Barrett, The Honors College at Arizona State University proudly showcases the work of undergraduate honors students by sharing this collection exclusively with the ASU community.
Barrett accepts high performing, academically engaged undergraduate students and works with them in collaboration with all of the other academic units at Arizona State University. All Barrett students complete a thesis or creative project which is an opportunity to explore an intellectual interest and produce an original piece of scholarly research. The thesis or creative project is supervised and defended in front of a faculty committee. Students are able to engage with professors who are nationally recognized in their fields and committed to working with honors students. Completing a Barrett thesis or creative project is an opportunity for undergraduate honors students to contribute to the ASU academic community in a meaningful way.
Displaying 1 - 3 of 3
Description
For the past couple decades, there has been a continuous rise in obesity and Type II Diabetes which has been attributed to the rise in calorically dense diets, especially those heavy in fats. Because of its rising prevalence, accompanied health concerns, and high healthcare costs, detection and therapies for these metabolic diseases are in high demand. Insulin resistance is a typical hallmark of Type II Diabetes and the metabolic deficiencies in obesity and is the main focus of this project. The primary purpose of this study is (1) detect the presence of two types of insulin resistance (peripheral and hepatic) as a function of age, (2) distinguish if diet impacted the presence of insulin resistance, and (3) determine both the short-term and long-term effects of caloric restriction on metabolic health. The following study longitudinally observed the changes in insulin resistance in high-fat fed and low-fat fed rodents under ad libitum and caloric restriction conditions over the course of 23 weeks. Fasting blood glucose, fasting insulin, body weight, and sensitivity of insulin on tissue were monitored in order to determine peripheral and hepatic insulin resistance. A high fat diet resulted in higher body weights and higher hepatic insulin resistance with no notable effect on peripheral insulin resistance. Caloric restriction was found to alleviate insulin resistance both during caloric restriction and four weeks after caloric restriction ended. Due to sample size, the generalizability of the findings in this study are limited. However, the current study did provide considerable results and can be viewed as a pilot study for a larger-scale study.
ContributorsZuo, Dana (Author) / Trumble, Benjamin (Thesis director) / Herman, Richard (Committee member) / Department of Psychology (Contributor) / School of Molecular Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
The field of study that this topic is derived from constitutes both federal aviation regulation as well as medical and biological sciences. The compelling idea of this thesis is an in depth investigation of the Federal Aviation Administration's (FAA) regulation and data collection throughout time regarding pilots with Insulin Treated Diabetes Mellitus (ITDM). When in comparison to the continuous evolution of diabetic research and endocrinology in all parts of the world, the regulations regarding this group of pilots seems displaced. This paper explores a chronological order of FAA research and regulations that were conducted on diabetic pilots stemming from 1959 - present. The findings seem to convey that the field of aviation is laden with inconsistencies and misplaced conclusions regarding regulation of insulin-treated diabetic pilots. This paper reflects on the impact of these regulations on this group of pilots from both a biological and medical standpoint as well as from an aviation point of view. In light of advanced medical knowledge, the paper explores what regulations regarding ITDM are in other countries and how FAA regulation should be refined and altered to realign with present day medical knowledge in the United States. This research was conducted to compare the sequential endocrinologic knowledge conducted and the subsequent regulatory actions.
ContributorsCorbitt, Tatiana Maria (Co-author) / Bartlowe, Halie (Co-author) / Caron, Martha (Thesis director) / O'Brien, Marc (Committee member) / College of Integrative Sciences and Arts (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
The field of study that this topic is derived from constitutes both federal aviation regulation as well as medical and biological sciences. The compelling idea of this thesis is an in depth investigation of the Federal Aviation Administration's (FAA) regulation and data collection throughout time regarding pilots with Insulin Treated Diabetes Mellitus (ITDM). When in comparison to the continuous evolution of diabetic research and endocrinology in all parts of the world, the regulations regarding this group of pilots seems displaced. This paper explores a chronological order of FAA research and regulations that were conducted on diabetic pilots stemming from 1959 - present. The findings seem to convey that the field of aviation is laden with inconsistencies and misplaced conclusions regarding regulation of insulin-treated diabetic pilots. This paper reflects on the impact of these regulations on this group of pilots from both a biological and medical standpoint as well as from an aviation point of view. In light of advanced medical knowledge, the paper explores what regulations regarding ITDM are in other countries and how FAA regulation should be refined and altered to realign with present day medical knowledge in the United States. This research was conducted to compare the sequential endocrinologic knowledge conducted and the subsequent regulatory actions.
ContributorsBartlowe, Halie Marie (Co-author) / Corbitt, Tatiana (Co-author) / O'Brien, Marc (Thesis director) / Caron, Martha (Committee member) / Aviation Programs (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05