Barrett, The Honors College Thesis/Creative Project Collection
Barrett, The Honors College at Arizona State University proudly showcases the work of undergraduate honors students by sharing this collection exclusively with the ASU community.
Barrett accepts high performing, academically engaged undergraduate students and works with them in collaboration with all of the other academic units at Arizona State University. All Barrett students complete a thesis or creative project which is an opportunity to explore an intellectual interest and produce an original piece of scholarly research. The thesis or creative project is supervised and defended in front of a faculty committee. Students are able to engage with professors who are nationally recognized in their fields and committed to working with honors students. Completing a Barrett thesis or creative project is an opportunity for undergraduate honors students to contribute to the ASU academic community in a meaningful way.
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Description
The purpose of this study is to examine the effect of an existing medication management program in Hispanic individuals with diabetes, focusing on overall management and perceived quality of life (QOL). Diseases such as diabetes affect an individual's physical health, mental health, and social life. The degree to which these diseases affect an individual's life depend on how well they control and self-manage care needs. It has been found that Hispanic patients report and demonstrate inadequacy with controlling their diabetes compared to other ethnicities, making this an important public health topic (Schneiderman eta al., 2014). One of the greatest issues the Hispanic population reports as causing most concern is medication management and compliance. Poor medication adherence can increase complications of diabetes and depression, thus increasing poor overall health status and perception. Medication therapy management (MTM) programs run by clinical pharmacists are available to help with medication adherence, aiding in developing a tailored plan to help individuals manage the disease. This study is a cross-sectional study which assess reported QOL and functionality of diabetics enrolled in an MTM program. Participants were recruited from a clinic in Phoenix, Az. Patients completed a questionnaire that included demographics, a QOL questionnaire and a health belief questionnaire. A total of sixteen participants completed the study. The association between time in the medication therapy management program and its effect on general health, social functioning, emotional well-being, and hemoglobin A1C were reviewed. Though no significance was found, means were similar in all groups indicating functionality and A1C control through the diabetes support program may exist.
ContributorsVarela, Zury Arely (Author) / Flom-Racoma, Kehart (Thesis director) / Ohri-Vachaspati, Punam (Committee member) / Arizona State University. College of Nursing & Healthcare Innovation (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
Description
According to the CDC, diabetes is the 7th leading cause of death in the U.S. and rates are continuing to rise nationally and internationally. Chronically elevated blood glucose levels can lead to type 2 diabetes and other complications. Medications can be used to treat diabetes, but often have side effects. Lifestyle and diet modifications can be just as effective as medications in helping to improve glycemic control, and prevent diabetes or improve the condition in those who have it. Studies have demonstrated that consuming vinegar with carbohydrates can positively impact postprandial glycemia in diabetic and healthy individuals. Continuous vinegar intake with meals may even reduce fasting blood glucose levels. Since vinegar is a primary ingredient in mustard, the purpose of this study was to determine if mustard consumption with a carbohydrate-rich meal (bagel and fruit juice) had an effect on the postprandial blood glucose levels of subjects. The results showed that mustard improved glycemia by 17% when subjects consumed the meal with mustard as opposed to the control. A wide variety of vinegars exists. The defining ingredient in all vinegars is acetic acid, behind the improvement in glycemic response observed with vinegar ingestion. Vinegar-containing foods range from mustard, to vinaigrette dressings, to pickled foods. The benefits of vinegar ingestion with carbohydrates are dose-dependent, meaning that adding even small amounts to meals can help. Making a conscious effort to incorporate these foods into meals, in addition to an overall healthy lifestyle, could provide an additional tool for diabetics and nondiabetics alike to consume carbohydrates in a healthier manner.
ContributorsJimenez, Gabriela (Author) / Johnston, Carol (Thesis director) / Lespron, Christy (Committee member) / School of Nutrition and Health Promotion (Contributor) / School of International Letters and Cultures (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
Description
This project details the synthesis and analysis of five analogs of model compound NEt-4IB (6-[ethyl(4-isobutoxy-3-isopropylphenyl)amino]nicotinic acid), that target the retinoid-X-receptor (RXR). These molecules were synthesized by substituting, adding, or removing substituents in the nitrogen-containing ring of NEt-4IB. The parent compound is a RXR partial agonist and has proven to be effective in the treatment of type II diabetes without the unwanted side effects seen with full agonists. Many of the current drugs used to treat type II diabetes are accompanied by adverse effects including increased triglyceride levels, weight gain, and hypoglycemia. Biological evaluation with KK-Ay (obese diabetic) model mice indicates that NEt-4IB may even be more effective than current drugs on the market, like pioglitazone. As a result, it is predicted that due to such structural similarity, the analogs synthesized for this work will perform equally, if not better than, NEt-4IB.
ContributorsMaiorella, Emma Lauren (Author) / Wagner, Carl (Thesis director) / Marshall, Pamela (Committee member) / School of Mathematical and Natural Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
ContributorsDolan, Kattie (Author) / Leong, Karen (Thesis director) / Wilson, Bradley (Committee member) / Barrett, The Honors College (Contributor)
Created2016-12
Description
The Community Action Research Experiences (CARE) program collaborated with Singleton Moms, a local non-profit organization that provides financial, psychological, and social support services to single parents with cancer. The purpose of this action research project was to assess the volunteer program at Singleton Moms. Both past and present Singleton Moms' volunteers (N = 123; 87.0% female) completed an online survey assessing their motivation for volunteering and their satisfaction with the organization. A mixed ANOVA was conducted to identify the most important motivation and satisfaction domains and to see if the findings depended on whether the volunteers were current or past volunteers. For the motivation assessment, results indicated that the volunteers rate the cancer specific and moral/human kindness domains as the strongest reasons for motivating them to volunteer at Singleton Moms. In addition, results revealed that the social connection motivation domain was the only domain with differences between the ratings of the past and present volunteers. For the satisfaction assessment, results indicated that the volunteers rate the organizational climate domain as the most fulfilled area of satisfaction within the Singleton Moms' volunteer program. It was also revealed that there were no significant differences between the ratings of the past and present volunteers among all satisfaction domains. Both the quantitative and qualitative findings suggest that Singleton Moms' implications for action may include: 1) a volunteer database audit, 2) streamlining communications, 3) variability in volunteer times, and 4) bolstering volunteer motivation. Implementing some of these actions may help Singleton Moms increase volunteer motivation and satisfaction and thus create a more effective volunteer program. Ultimately, this may encourage volunteers to continue their services at Singleton Moms and thus help Singleton Moms expand their support programs and assist additional families.
ContributorsDubois, Courtney Michelle (Author) / Miller, Cindy (Thesis director) / Dumka, Larry (Committee member) / Harrington Bioengineering Program (Contributor) / Barrett, The Honors College (Contributor) / T. Denny Sanford School of Social and Family Dynamics (Contributor)
Created2016-05
Description
Traumatic brain injury (TBI) is a leading cause of injury related death in the United States. The complexity of the injury environment that follows TBI creates an incomplete understanding of all the mechanisms in place to regulate chemotactic responses to TBI. The goal of this project was to develop a predictive in silco model using diffusion and autocrine/paracrine signaling specific to stromal cell derived factor-1α (SDF-1α) gradient formation after TBI and compare this model with in vivo experimental data. A COMSOL model using Fickian diffusion and autocrine/paracrine reaction terms was generated to predict the gradient formation observed in vivo at three physiologically relevant time points (1, 3, and 7 days). In vivo data was gathered and analyzed via immunohistochemistry and MATLAB. The spatial distribution of SDF-1α concentration in vivo more consistently demonstrated patterns similar to the in silico model dependent on both diffusion and autocrine/paracrine reaction terms rather than diffusion alone. The temporal distribution of these same results demonstrated degradation of SDF-1α at too rapid a rate, compared to the in vivo results. To account for differences in behavior observed in vivo, reaction terms and constants of 1st-order reaction rates must be modulated to better reflect the results observed in vivo. These results from both the in silico model and in vivo data support the hypothesis that SDF-1α gradient formation after TBI depends on more than diffusion alone. Future work will focus on improving the model with constants that are specific to SDF-1α as well as testing methods to better control the degradation of SDF-1α.
ContributorsFreeman, Sabrina Louise (Author) / Stabenfeldt, Sarah (Thesis director) / Caplan, Michael (Committee member) / Harrington Bioengineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
Description
Community Music Therapy for Cultural Cohesion is the name of the research initiative to create a community music therapy program that addresses community attitudes toward cultural diversity. The program created is titled "Many Peoples, One Voice." Theories and findings in the field of social psychology regarding the formation of intergroup bias and how to prevent it from taking hold inform the goals of the program. Current practices in and theories on community music therapy inform the content, qualities, and perspective of the program. Information from the field of ethnomusicology inform the specific world music traditions incorporated into the program. The culmination of this research and the program it birthed is described in detail to promote a better understanding of the goals, activities, cultural handouts, additional content considerations, and structure of the program as well as the populations it may serve and the adaptions it may include. Finally, the program is related to the current trends in the field of music therapy and its potential to expand into nontraditional need and population areas is considered.
ContributorsOstrowski, Jennifer Lauren (Author) / Rio, Robin (Thesis director) / Little, Bliss (Committee member) / School of Music (Contributor) / Barrett, The Honors College (Contributor)
Created2015-12
Description
There is a widespread inequality in health care access and insured rates suffered by the Latino, Spanish-speaking population in Arizona, resulting in poor health measures and economic burden. The passage of the Affordable Care Act in 2010 provided mechanisms to alleviate this disparity, however, many Latino communities lack accessible information and means to gain access to health insurance enrollment. Chicanos Por La Causa (CPLC) is a community based organizing that provides many services to low-income communities across Arizona, one of which is the CPLC Insurance Program. In collaboration with the Community Action Research Experiences (CARE) at Arizona State University, the program was studied to help address the need of a LOGIC model and evaluation plan to determine its effectiveness. Interviews with three executives within CPLC were conducted in conjunction with a literature review to determine the inputs, strategies, outputs, and outcomes of the LOGIC model that drive CPLC Insurance's mission. Evaluation measures were then created to provide the necessary quantitative data that can best show to what degree the program is achieving its goals. Specifically, the results indicated the key outcomes that drive the LOGIC model, and an evaluation plan designed to provide indicators of these outcomes was produced. The implications of this study are that the suggested data collection can verify how effectively the program's actions are creating positive change, as well as show where further improvements may be necessary to maximize effectiveness.
ContributorsCunningham, Matthew Lee (Author) / Fey, Richard (Thesis director) / Dumka, Larry (Committee member) / School of Molecular Sciences (Contributor) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor) / T. Denny Sanford School of Social and Family Dynamics (Contributor)
Created2016-05