Barrett

Barrett, The Honors College at Arizona State University proudly showcases the work of undergraduate honors students by sharing this collection exclusively with the ASU community.

Barrett accepts high performing, academically engaged undergraduate students and works with them in collaboration with all of the other academic units at Arizona State University. All Barrett students complete a thesis or creative project which is an opportunity to explore an intellectual interest and produce an original piece of scholarly research. The thesis or creative project is supervised and defended in front of a faculty committee. Students are able to engage with professors who are nationally recognized in their fields and committed to working with honors students. Completing a Barrett thesis or creative project is an opportunity for undergraduate honors students to contribute to the ASU academic community in a meaningful way.

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ASU Farmers Market

Description
The implementation of a farmers market on the Arizona State University Tempe campus would benefit student helath, the local community, and the environment. A 2009 survey of university students states that "over 60 percent [of students] eat two or fewer servings of fruits and vegetables a day," which falls below…

The implementation of a farmers market on the Arizona State University Tempe campus would benefit student helath, the local community, and the environment. A 2009 survey of university students states that "over 60 percent [of students] eat two or fewer servings of fruits and vegetables a day," which falls below the health standard. A campus farmers market would give students easier access to fresh produce. Through purchasing products from local vendors, students will establish better connections with the community while supporting the local economy. In addition, farmers markets encourage sustainable practices. According to a survey conducted by Farmers Markets Today, "85% of farmers market vendors traveled fewer than 50 miles to sell at a famers market [while]... nationwide, food travels an average of 1,500 miles before reaching its consumer." Thus, greenhouse gas emissions can be significantly reduced through purchasing local products. The purposes of a campus farmers market act in conjunction with ASU's intentions to become a New American University, which values students' well-being, the local community, and sustainability.
ContributorsSienicki, Joey (Author) / Van Fleet, David (Thesis director) / Bronowitz, Jason (Committee member) / Smith, Emily (Committee member) / Barrett, The Honors College (Contributor)
Created2010-05
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Modeling SDF-1α Chemotactic Gradient Formation After Traumatic Brain Injury

Description
Traumatic brain injury (TBI) is a leading cause of injury related death in the United States. The complexity of the injury environment that follows TBI creates an incomplete understanding of all the mechanisms in place to regulate chemotactic responses to TBI. The goal of this project was to develop a…

Traumatic brain injury (TBI) is a leading cause of injury related death in the United States. The complexity of the injury environment that follows TBI creates an incomplete understanding of all the mechanisms in place to regulate chemotactic responses to TBI. The goal of this project was to develop a predictive in silco model using diffusion and autocrine/paracrine signaling specific to stromal cell derived factor-1α (SDF-1α) gradient formation after TBI and compare this model with in vivo experimental data. A COMSOL model using Fickian diffusion and autocrine/paracrine reaction terms was generated to predict the gradient formation observed in vivo at three physiologically relevant time points (1, 3, and 7 days). In vivo data was gathered and analyzed via immunohistochemistry and MATLAB. The spatial distribution of SDF-1α concentration in vivo more consistently demonstrated patterns similar to the in silico model dependent on both diffusion and autocrine/paracrine reaction terms rather than diffusion alone. The temporal distribution of these same results demonstrated degradation of SDF-1α at too rapid a rate, compared to the in vivo results. To account for differences in behavior observed in vivo, reaction terms and constants of 1st-order reaction rates must be modulated to better reflect the results observed in vivo. These results from both the in silico model and in vivo data support the hypothesis that SDF-1α gradient formation after TBI depends on more than diffusion alone. Future work will focus on improving the model with constants that are specific to SDF-1α as well as testing methods to better control the degradation of SDF-1α.
ContributorsFreeman, Sabrina Louise (Author) / Stabenfeldt, Sarah (Thesis director) / Caplan, Michael (Committee member) / Harrington Bioengineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05