Barrett, The Honors College at Arizona State University proudly showcases the work of undergraduate honors students by sharing this collection exclusively with the ASU community.

Barrett accepts high performing, academically engaged undergraduate students and works with them in collaboration with all of the other academic units at Arizona State University. All Barrett students complete a thesis or creative project which is an opportunity to explore an intellectual interest and produce an original piece of scholarly research. The thesis or creative project is supervised and defended in front of a faculty committee. Students are able to engage with professors who are nationally recognized in their fields and committed to working with honors students. Completing a Barrett thesis or creative project is an opportunity for undergraduate honors students to contribute to the ASU academic community in a meaningful way.

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Traumatic brain injury (TBI) is a leading cause of injury related death in the United States. The complexity of the injury environment that follows TBI creates an incomplete understanding of all the mechanisms in place to regulate chemotactic responses to TBI. The goal of this project was to develop a

Traumatic brain injury (TBI) is a leading cause of injury related death in the United States. The complexity of the injury environment that follows TBI creates an incomplete understanding of all the mechanisms in place to regulate chemotactic responses to TBI. The goal of this project was to develop a predictive in silco model using diffusion and autocrine/paracrine signaling specific to stromal cell derived factor-1α (SDF-1α) gradient formation after TBI and compare this model with in vivo experimental data. A COMSOL model using Fickian diffusion and autocrine/paracrine reaction terms was generated to predict the gradient formation observed in vivo at three physiologically relevant time points (1, 3, and 7 days). In vivo data was gathered and analyzed via immunohistochemistry and MATLAB. The spatial distribution of SDF-1α concentration in vivo more consistently demonstrated patterns similar to the in silico model dependent on both diffusion and autocrine/paracrine reaction terms rather than diffusion alone. The temporal distribution of these same results demonstrated degradation of SDF-1α at too rapid a rate, compared to the in vivo results. To account for differences in behavior observed in vivo, reaction terms and constants of 1st-order reaction rates must be modulated to better reflect the results observed in vivo. These results from both the in silico model and in vivo data support the hypothesis that SDF-1α gradient formation after TBI depends on more than diffusion alone. Future work will focus on improving the model with constants that are specific to SDF-1α as well as testing methods to better control the degradation of SDF-1α.
ContributorsFreeman, Sabrina Louise (Author) / Stabenfeldt, Sarah (Thesis director) / Caplan, Michael (Committee member) / Harrington Bioengineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
Description

Crazed Oasis strives to create a community-based, sustainable clothing brand that looks and feels great, while creating a community that is safe and welcoming to individuals of all backgrounds. We strive to educate all about the world to provide an understanding and appreciation for all individuals and cultures. The current

Crazed Oasis strives to create a community-based, sustainable clothing brand that looks and feels great, while creating a community that is safe and welcoming to individuals of all backgrounds. We strive to educate all about the world to provide an understanding and appreciation for all individuals and cultures. The current climate of the world is a crazy one, and the clothing industry is highly unsustainable. Crazed Oasis is creating the solution by building a community to create new friendships and connections while focusing on the important topics of the world, such as sustainability, mental health, human rights, arts and passions, and more. Through our clothing products, we will educate and create a culture of understanding through art.

ContributorsEllis, Connor (Author) / Byrne, Jared (Thesis director) / Lawson, Brennan (Committee member) / Plunkett, Nina (Committee member) / Higashino, Kat (Committee member) / Bauer, Nolan (Committee member) / Stephan, Roman (Committee member) / Adarsh, Sid (Committee member) / Barrett, The Honors College (Contributor) / The Design School (Contributor) / Department of Marketing (Contributor)
Created2023-05
Description

There is a serious lack of local news in Arizona, the American Southwest, and the United States at-large. Arizonans are craving quality, factual, no-holds-barred journalism that is easy-to-read, and upfront. Quality, local news that covers the ins and outs of politics, culture, and community has an opportunity to not only

There is a serious lack of local news in Arizona, the American Southwest, and the United States at-large. Arizonans are craving quality, factual, no-holds-barred journalism that is easy-to-read, and upfront. Quality, local news that covers the ins and outs of politics, culture, and community has an opportunity to not only enhance civic life, promote community healing, and expand knowledge made available to the general public (thus serving the communities it calls home), but to also generate revenue. Further, independent and center-right leaning voters in the state of Arizona — be reminded that independents make up the second largest voting bloc among Arizonans — are often crowded out in a media environment that consists of far-left nonprofit-funded news sites like the Arizona Mirror, formerly reputable papers that have bled readership as they veer further left like the Arizona Republic, and far-right online blogs that reach a very limited audience. The Western Tribune is an Arizona-based journalistic publication. This institution is dedicated to providing high-quality, well-sourced news and commentary on statewide, regional, national, and international current affairs through the lens of good government and free enterprise — as well as Southwestern values. We are a free institution that believes in free institutions. We cover stories that go uncovered because of the corporate media’s blind spots (and they’ve got many — they’re a result of news deserts and out-of-touch coastal attitudes) with the stable support of a robust institution dedicated to Truth-seeking behind them. Our storytellers are not just good writers. We seek to recruit and form critical thinkers with skills that span trades, disciplines, and educational backgrounds. We are building an institution committed to excellence.

ContributorsRobinson, Clay (Author) / Byrne, Jared (Thesis director) / Swader, Melissa (Committee member) / Plunkett, Nina (Committee member) / Khalaf, George (Committee member) / Barrett, The Honors College (Contributor) / Thunderbird School of Global Management (Contributor) / School for the Future of Innovation in Society (Contributor) / School of Public Affairs (Contributor) / School of Politics and Global Studies (Contributor) / School of Civic & Economic Thought and Leadership (Contributor)
Created2023-05