Barrett, The Honors College Thesis/Creative Project Collection
Barrett, The Honors College at Arizona State University proudly showcases the work of undergraduate honors students by sharing this collection exclusively with the ASU community.
Barrett accepts high performing, academically engaged undergraduate students and works with them in collaboration with all of the other academic units at Arizona State University. All Barrett students complete a thesis or creative project which is an opportunity to explore an intellectual interest and produce an original piece of scholarly research. The thesis or creative project is supervised and defended in front of a faculty committee. Students are able to engage with professors who are nationally recognized in their fields and committed to working with honors students. Completing a Barrett thesis or creative project is an opportunity for undergraduate honors students to contribute to the ASU academic community in a meaningful way.
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Description
Traumatic brain injury (TBI) is a leading cause of injury related death in the United States. The complexity of the injury environment that follows TBI creates an incomplete understanding of all the mechanisms in place to regulate chemotactic responses to TBI. The goal of this project was to develop a predictive in silco model using diffusion and autocrine/paracrine signaling specific to stromal cell derived factor-1α (SDF-1α) gradient formation after TBI and compare this model with in vivo experimental data. A COMSOL model using Fickian diffusion and autocrine/paracrine reaction terms was generated to predict the gradient formation observed in vivo at three physiologically relevant time points (1, 3, and 7 days). In vivo data was gathered and analyzed via immunohistochemistry and MATLAB. The spatial distribution of SDF-1α concentration in vivo more consistently demonstrated patterns similar to the in silico model dependent on both diffusion and autocrine/paracrine reaction terms rather than diffusion alone. The temporal distribution of these same results demonstrated degradation of SDF-1α at too rapid a rate, compared to the in vivo results. To account for differences in behavior observed in vivo, reaction terms and constants of 1st-order reaction rates must be modulated to better reflect the results observed in vivo. These results from both the in silico model and in vivo data support the hypothesis that SDF-1α gradient formation after TBI depends on more than diffusion alone. Future work will focus on improving the model with constants that are specific to SDF-1α as well as testing methods to better control the degradation of SDF-1α.
ContributorsFreeman, Sabrina Louise (Author) / Stabenfeldt, Sarah (Thesis director) / Caplan, Michael (Committee member) / Harrington Bioengineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
Description
The Southern Baptist Convention’s missional branch, North American Mission Board, and their church planting subsidiary, Send Network, failed to provide online communication guidance to help establish (or plant) new faith communities. Only 13% of Evangelical Protestants are under the age of thirty (Pew Research Center, 2015). If the Southern Baptist Convention wants their church plants to grow in a media-focused society, they must learn how to communicate with the generations who were born with technology in their hands. The purpose of this study is to identify which content and frequency Southern Baptist Churches in Metropolitan Phoenix should use to reach their target community.
The project began by conducting research on twelve Send Network church plants within fifteen miles of the center of downtown Phoenix. The results led to drafting a communications and branding guideline for one of the Send Network’s church plants, Mercy Hill Church, creating a ten-week posting schedule to collect insights on content and frequency of posts, analyzing and identifying best practices for its social media strategy and tactics.
The ideal posting schedule and ratio of still image and video content for Mercy Hill Church on Instagram and Facebook was revealed. Additionally, it was identified the best day of the week to publish each type of post out of these seven: community, Scripture, worship, testimony, ministry highlight, sermon recap and church invite.
Overall, the project determined that a consistent and cohesive Instagram and Facebook posting schedule increased traditional college-aged student engagement with Mercy Hill Church. It also resulted in an ideal posting schedule for Southern Baptist church plants if their target audience includes traditional college-aged students.
ContributorsDellaripa, Amelia (Author) / Matera, Frances (Thesis director) / Hass, Mark (Committee member) / Barrett, The Honors College (Contributor) / Walter Cronkite School of Journalism and Mass Comm (Contributor)
Created2023-12