Barrett, The Honors College Thesis/Creative Project Collection
Barrett, The Honors College at Arizona State University proudly showcases the work of undergraduate honors students by sharing this collection exclusively with the ASU community.
Barrett accepts high performing, academically engaged undergraduate students and works with them in collaboration with all of the other academic units at Arizona State University. All Barrett students complete a thesis or creative project which is an opportunity to explore an intellectual interest and produce an original piece of scholarly research. The thesis or creative project is supervised and defended in front of a faculty committee. Students are able to engage with professors who are nationally recognized in their fields and committed to working with honors students. Completing a Barrett thesis or creative project is an opportunity for undergraduate honors students to contribute to the ASU academic community in a meaningful way.
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Description
The passage of 2007's Legal Arizona Workers Act, which required all new hires to be tested for legal employment status through the federal E-Verify database, drastically changed the employment prospects for undocumented workers in the state. Using data from the 2007-2010 American Community Survey, this paper seeks to identify the impact of this law on the labor force in Arizona, specifically regarding undocumented workers and less educated native workers. Overall, the data shows that the wage bias against undocumented immigrants doubled in the four years studied, and the wages of native workers without a high school degree saw a temporary, positive increase compared to comparable workers in other states. The law did not have an effect on the wages of native workers with a high school degree.
ContributorsSantiago, Maria Christina (Author) / Pereira, Claudiney (Thesis director) / Mendez, Jose (Committee member) / School of International Letters and Cultures (Contributor) / Department of Economics (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
Transient Receptor Potential (TRP) ion channels are a diverse family of nonselective, polymodal sensors in uni- and multicellular eukaryotes that are implicated in an assortment of biological contexts and human disease. The cold-activated TRP Melastatin-8 (TRPM8) channel, also recognized as the human body's primary cold sensor, is among the few TRP channels responsible for thermosensing. Despite sustained interest in the channel, the mechanisms underlying TRPM8 activation, modulation, and gating have proved challenging to study and remain poorly understood. In this thesis, I offer data collected on various expression, extraction, and purification conditions tested in E. Coli expression systems with the aim to optimize the generation of a structurally stable and functional human TRPM8 pore domain (S5 and S6) construct for application in structural biology studies. These studies, including the biophysical technique nuclear magnetic spectroscopy (NMR), among others, will be essential for elucidating the role of the TRPM8 pore domain in in regulating ligand binding, channel gating, ion selectively, and thermal sensitivity. Moreover, in the second half of this thesis, I discuss the ligation-independent megaprimer PCR of whole-plasmids (MEGAWHOP PCR) cloning technique, and how it was used to generate chimeras between TRPM8 and its nearest analog TRPM2. I review steps taken to optimize the efficiency of MEGAWHOP PCR and the implications and unique applications of this novel methodology for advancing recombinant DNA technology. I lastly present preliminary electrophysiological data on the chimeras, employed to isolate and study the functional contributions of each individual transmembrane helix (S1-S6) to TRPM8 menthol activation. These studies show the utility of the TRPM8\u2014TRPM2 chimeras for dissecting function of TRP channels. The average current traces analyzed thus far indicate that the S2 and S3 helices appear to play an important role in TRPM8 menthol modulation because the TRPM8[M2S2] and TRPM8[M2S3] chimeras significantly reduce channel conductance in the presence of menthol. The TRPM8[M2S4] chimera, oppositely, increases channel conductance, implying that the S4 helix in native TRPM8 may suppress menthol modulation. Overall, these findings show that there is promise in the techniques chosen to identify specific regions of TRPM8 crucial to menthol activation, though the methods chosen to study the TRPM8 pore independent from the whole channel may need to be reevaluated. Further experiments will be necessary to refine TRPM8 pore solubilization and purification before structural studies can proceed, and the electrophysiology traces observed for the chimeras will need to be further verified and evaluated for consistency and physiological significance.
ContributorsWaris, Maryam Siddika (Author) / Van Horn, Wade (Thesis director) / Redding, Kevin (Committee member) / School of Molecular Sciences (Contributor) / Department of English (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
Description
Searching for home: An in depth look at undocumented youth in Arizona from their perspective, a research and creative project, looks at not only the history and data surrounding unauthorized immigration, but a personal account through the stories of undocumented immigrants. The research paper focuses on the policies, court cases and history of protests that surround the topics. The article under Appendix A focuses on the personal stories and accounts of two undocumented immigrants who discuss the importance of fighting to stay in the U.S. and preserving the dream and life they built. Two videos also explore the emotional stories of the undocumented immigrants and those who live on the border. The first video features two undocumented immigrants who discuss their beliefs in protesting and working to stay in the U.S. The second video features two women who have lived in both Mexico and the U.S. legally and discuss how immigration and border policies affect them.
ContributorsMacklin, Alexis Isabella (Author) / Angela, Kocherga (Thesis director) / David, Seibert (Committee member) / School of Human Evolution and Social Change (Contributor) / Walter Cronkite School of Journalism and Mass Communication (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
Description
A look at how the Vietnam War influenced immigrant and first-generation children's perception of culture. This thesis focuses on Vietnamese-American immigration as a whole, and on subjects on the American west coast. Interviews were conducted with eleven subjects to examine the most profound influences on culture and how native culture is passed on through the generations. Focuses include cultural identity, cultural inheritance, prominent native and adoptive cultural values, and culture as affected by adversity.
ContributorsTran, Yvana (Author) / Loebenberg, Abby (Thesis director) / Suk, Mina (Committee member) / Barrett, The Honors College (Contributor)
Created2017-05
Description
This project is to help Guatemalan youth immigrants by providing them with the information necessary to access support in the United States, and obtainin legal status in the United States. In order to produce a brochure with this information, it was necessary to research the political, economic, and social history of Guatemala in order to determine what struggles citizens are facing, and specifically what experiences youth in the country have prior to their journey to the United States. This research is culminated into a paper that discusses the history, the causes of emigration from Guatemala, and the status of youth immigrants before they leave Guatemala and once they arrive in the United States.
ContributorsMckay, Rachel Marie (Author) / Magaña, Lisa (Thesis director) / Elias, Olivia (Committee member) / School of Criminology and Criminal Justice (Contributor) / School of Politics and Global Studies (Contributor) / College of Letters and Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
Description
Unauthorized confronts the relationship between technology and personhood in the modern world. More specifically, it addresses the personal and social effects of border politics within the frame of cyber crime. The short film takes place in the near future where a hacker can create citizenship for anyone she wants, effectively turning anyone into a legal person in the United States. This parallels the real life struggles of unauthorized immigrants trying to gain a new life this side of the border despite the overwhelming backlash from the conservative and xenophobic population. The main character's ability to grant citizenship forces the viewer to confront what being a person really means. The film also alludes to the popularized antics of modern day hackers and whistleblowers who are often turned into heroes for fighting the establishment despite their character flaws. The protagonist of Unauthorized struggles through underhanded sexism and blatant racism as well as her own personal struggles with drug addiction and failed relationships. These are very real struggles women face in technology jobs and life in general. The main character's actions ultimately destroy every relationship that she's established, including the connection to her own family. This film, in short, is about the walls people build between each other, both physical and social.
ContributorsStabley, Justin E. (Author) / Bradley, Christopher (Thesis director) / Baker, Aaron (Committee member) / Department of English (Contributor) / Walter Cronkite School of Journalism and Mass Communication (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
Description
This thesis examines the problems that occur when the politics and practices of social services, specifically maternal and prenatal care, are guided by a distorted understanding of immigration. It compares the politics and practice of this care across two international borders: the U.S.-Mexico and that within Hispaniola. In an ideal world, care would be extended to all individuals regardless of citizenship. However, since every welfare state has its limits at the national border, citizenship matters to both federal governments and medical professionals. Government-provided resources play an integral role in the current immigration debate, as these programs are a collective investment in which all individuals contribute in order to sustain it. The United States developed the welfare state in order to provide necessary resources to those who could not afford it. Its creators did not view these services as a handout, rather as a support for the future workforce of the country. However, health care was and still is not provided on this model of economic and social citizenship. Current U.S. healthcare policy dictates that no one can be turned away in an emergency situation because someone cannot pay their medical bill, including undocumented immigrants. But for immigrant mothers carrying children across the border, maternal and prenatal care does not qualify as an emergency and the federal government aid typically does not extend to them them as citizens. When care is extended to undocumented immigrants in the United States at all, it typically is provided to the child through Medicaid, who is by dint of the Fourteenth Amendment considered a citizen after birth. The relation between the Dominican Republic and Haiti offers a more complex situation, as the idea of birthright citizenship has recently been revoked. Following the Haitian Earthquake in 2010, the only healthcare to which many Haitians had access was across the Hispaniola border. Haitian women who give birth to children in the Dominican Republic are often not evaluated by a doctor until they are entering the delivery process, and even then health-care is complicated by or denied because of racial prejudice and unclear legal situation. In September of 2013, the Constitutional Court of the Dominican Republic issues a new ruling which declared that any immigrant born between 1929 and 2010 without documentation of their own or of their ancestors does not have citizenship, rendering many Haitians born in the Dominican Republic essentially stateless. To be born to a non-citizen mother typically means the child will likely be born with little or no prenatal care, and the mother will receive poor or inadequate care. Prenatal care is one of the most inexpensive elements of a care-model that carries huge returns relative to its costs. All governments would benefit from improved access to maternal and prenatal care because its future citizens who receive such care would be born healthier and have fewer expensive chronic illnesses. Fewer chronic illness among a population would have huge returns on the welfare state because fewer people would be utilizing it for expensive medical treatments. Though most medical professionals condemn the extreme act of denying care to pregnant women or infants (documented or not), the Dominican Republic and the United States have a popular politics that embraces this cruelty, despite the fact that both pride themselves on a multi-ethnic population. It is easy for policymakers to incriminate undocumented immigrants and claim that they are responsible for an illegitimate share of the consumption of the country's resources. Therefore, it seems likely that the host country's perceptions of immigrant natality and maternity help construct a negative image of the immigration "problem" in such a way that laws and policies are designed without accurate rationale. This thesis examines how the United States and the Dominican Republic might improve the relationship between the culture of healthcare and the role of the legal system for immigrants and their children. It seeks to understand the reasons, motivations, and consequences for denying immigrants services on the account of their citizenship status. The social, economic, and health consequences of being an undocumented citizen will be examined. Current legal policy and what political roadblocks and cultural prejudices must be overcome in order to implement a successful policy will be reviewed. Finally, the best practices prenatal care as a national investment will be discussed, as will the problem of cross-cultural perception of natality, maternity, and immigration.
ContributorsPrassas, Alexandra Rose (Author) / Oberle, Eric (Thesis director) / Vega, Sujey (Committee member) / Oberstein, Bruce (Committee member) / College of Letters and Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
Description
In 2012, President Obama presented an executive order, Deferred Action for Childhood Arrivals (DACA), which primarily defers the deportation of unauthorized immigrants who are under the age of 31 and who arrived to the US before the age 16, among other things. This study examines the impact DACA has had on the identity formation, interfamilial relationships, and future plans of 15 Mexican-origin adults (18-27 years old, 47% female) who were approved for DACA in Arizona. Participants were recruited using flyers and the snowball sampling method. Interviews were conducted using a semi-structured interview guide by a bilingual, culturally competent interviewer. The interviews were recorded and then a transcript-based pragmatic, thematic analysis of the interviews was conducted. Findings show that participants who arrive to the U.S. at a younger age (under 5) identify as American, while those who arrive at an older age (over 8) do not feel like they can identify as an American because they spent more time in Mexico and are more attached to their home culture. Physical characteristics also played a factor in whether or not participants felt like they could identify as American. Participants describe their financial responsibility in their families increasing since receiving DACA. They also describe how they are now seen as role models to other undocumented youth in their families. Despite the uncertain future of DACA, these participants continued to have ambitious goals such as becoming lawyers and working at robotics companies. Future studies should include larger sample sizes and formally test theories of identity.
ContributorsLopez, Alejandra (Author) / Diaz McConnell, Eileen (Thesis director) / Martinez, Airin (Committee member) / School of Social Transformation (Contributor) / School of Transborder Studies (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
Description
A series of mitochondria targeting probes was synthesized for the purpose of exploring the feasibility of a mitochondria targeting fluorescent sensor. Of the probes, the probe with a two carbon spacer showed the best co-localization from staining with the established MitoTracker Red® FM, indicating a potential development of the probe into mitochondria targeting sensor. However, cytotoxicity was observed for the probe with a six carbon spacer. Three additional mitochondria targeting fluorescent probes of longer spacer groups were synthesized, but the cytotoxicity was not observed to be as high as that of the probe with a two carbon spacer. The cytotoxicity was characterized to be that of caspase dependent cell death. To screen for a possible effect on apoptosis due to the mitochondrial probe, three fluorescent fusion proteins binding the anti-apoptotic proteins were designed and expressed. Each purified fusion protein was then incubated with the cytotoxic mitochondrial probe, and the mixture was isolated by running an affinity column. The fluorescence analysis of eluted fractions showed preliminary data of possible interaction between the protein and the mitochondrial probe.
ContributorsLee, Fred (Author) / Meldrum, Deirdre R. (Thesis director) / Tian, Yanqing (Committee member) / Zhang, Liqiang (Committee member) / Barrett, The Honors College (Contributor) / Chemical Engineering Program (Contributor) / Department of Chemistry and Biochemistry (Contributor)
Created2014-12
Description
This research looks at a group of students from Tumaini Children's Home in Nyeri, Kenya. The purpose of this paper is to explore why this particular group of students is so academically successful. Quantitative research was taken from the average 2013 test scores of Tumaini students who took the Kenyan Certificate of Primary Education (KCPE) exam in comparison to the scores of students who are not residing in the orphanage. Qualitative research involves interviews from those students who live in Tumaini and interviews from adults who are closely connected to the orphanage. The purpose is to understand why the students are performing so well academically and what support they have created for themselves that allows them to do so.
ContributorsTooker, Amy Elizabeth (Author) / Puckett, Kathleen (Thesis director) / Cocchiarella, Martha (Committee member) / Barrett, The Honors College (Contributor) / Division of Teacher Preparation (Contributor)
Created2014-12