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Cybersecurity and research do not have to be opposed to each other. With increasing cyberattacks, it is more important than ever for cybersecurity and research to corporate. The authors describe how Research Liaisons and Information Assurance: Michigan Medicine (IA:MM) collaborate at Michigan Medicine, an academic medical center subject to strict

Cybersecurity and research do not have to be opposed to each other. With increasing cyberattacks, it is more important than ever for cybersecurity and research to corporate. The authors describe how Research Liaisons and Information Assurance: Michigan Medicine (IA:MM) collaborate at Michigan Medicine, an academic medical center subject to strict HIPAA controls and frequent risk assess- ments. IA:MM provides its own Liaison to work with the Research Liaisons to better understand security process and guide researchers through the process. IA:MM has developed formal risk decision processes and informal engagements with the CISO to provide risk- based cybersecurity instead of controls-based. This collaboration has helped develop mitigating procedures for researchers when standard controls are not feasible.
ContributorsMcCaffrey, Deb (Author) / Kelley, Jessica (Author)
Created2022-07-14
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Description

Tikhonov regularization for projected solutions of large-scale ill-posed problems is considered. The Golub{Kahan iterative bidiagonalization is used to project the problem onto a subspace and regularization then applied to nd a subspace approximation to the full problem. Determination of the regularization, parameter for the projected problem by unbiased predictive risk

Tikhonov regularization for projected solutions of large-scale ill-posed problems is considered. The Golub{Kahan iterative bidiagonalization is used to project the problem onto a subspace and regularization then applied to nd a subspace approximation to the full problem. Determination of the regularization, parameter for the projected problem by unbiased predictive risk estimation, generalized cross validation, and discrepancy principle techniques is investigated. It is shown that the regularized parameter obtained by the unbiased predictive risk estimator can provide a good estimate which can be used for a full problem that is moderately to severely ill-posed. A similar analysis provides the weight parameter for the weighted generalized cross validation such that the approach is also useful in these cases, and also explains why the generalized cross validation without weighting is not always useful. All results are independent of whether systems are over- or underdetermined. Numerical simulations for standard one-dimensional test problems and two- dimensional data, for both image restoration and tomographic image reconstruction, support the analysis and validate the techniques. The size of the projected problem is found using an extension of a noise revealing function for the projected problem [I. Hn etynkov a, M. Ple singer, and Z. Strako s, BIT Numer. Math., 49 (2009), pp. 669{696]. Furthermore, an iteratively reweighted regularization approach for edge preserving regularization is extended for projected systems, providing stabilization of the solutions of the projected systems and reducing dependence on the determination of the size of the projected subspace.

ContributorsRenaut, Rosemary (Author)
Created2017-03-08