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Diabetes mellitus (DM) is a disease characterized by chronically elevated levels of glucose in the bloodstream. Glucose is a form of sugar that is used as fuel by the body’s cells. Blood glucose levels are usually tightly controlled and regulated through a negative feedback system. When this system fails, however,

Diabetes mellitus (DM) is a disease characterized by chronically elevated levels of glucose in the bloodstream. Glucose is a form of sugar that is used as fuel by the body’s cells. Blood glucose levels are usually tightly controlled and regulated through a negative feedback system. When this system fails, however, glucose can accumulate in the bloodstream. This system failure typically results from insufficient insulin release due to malfunctioning pancreatic beta cells or the body has developed a resistance to insulin. Excessive glucose accumulation contributes to chronic inflammation and the hardening of blood vessels in the body. This inflammation contributes to a multitude of debilitating health issues such as neuropathy, nephropathy, retinopathy, renal failure, and/or gangrene of the limbs. Additionally, DM is the 7th leading cause of death in the United States and its treatment comes with a significant economic deficit. While there is currently no cure, pharmaceuticals, dietary modification, physical activity, and weight control are the four main approaches for DM intervention and control. These four approaches each operate to regulate glucose using different biological pathways in order to reduce and regulate blood glucose levels. These pathways include improving insulin sensitivity and correcting pancreatic beta cell function. The purpose of this paper will be to provide an overview of type II diabetes mellitus (T2DM) as well as to review the physiological mechanisms involved with glucose control and finally to discuss the use and effectiveness of the main interventional approaches used with the treatment of T2DM: pharmaceuticals, dietary control, physical activity and weight control.
ContributorsWoods, Jessica M (Author) / Swan, Pamela (Thesis director) / Larson, Rachel (Committee member) / College of Health Solutions (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
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The objective of this thesis is to address, study and evaluate the current Veteran suicide epidemic and discuss current initiatives and recommended reforms to decrease Veteran suicide rates across the nation. This thesis holistically demonstrates the significance of this issue with presenting and analyzing extensive recent data and information gathered

The objective of this thesis is to address, study and evaluate the current Veteran suicide epidemic and discuss current initiatives and recommended reforms to decrease Veteran suicide rates across the nation. This thesis holistically demonstrates the significance of this issue with presenting and analyzing extensive recent data and information gathered from military reports. Next, this thesis assesses federal policies and programs along with statewide suicide prevention efforts created to mitigate this issue, including unique anecdotal evidence and observed data. In order to illustrate the nature and efficacy of current suicide prevention measures, this thesis carefully relies on information from diverse primary sources, examining stories, claims, and perspectives from state Veterans-affiliated leadership, some of whom are former service-members themselves. To comprehensively unite these various state profiles and perspectives, this thesis conducts careful theme-based analysis, studying and dissecting each state using a uniform set of themes. Finally, this thesis proposes thoughtful and evidence-based recommendations for future efforts to further decrease Veteran suicides, offering insights for key changes to important processes and federal reporting as well as suggestions for the implementation of specialized prevention efforts on a nationwide scale with the goal of promoting the welfare of our nation’s former service members.

ContributorsKapur, Ameya (Author) / Mokwa, Michael (Thesis director) / Eaton, John (Committee member) / Larson, Rachel (Committee member) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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Created1935