Matching Items (12)
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Description
The purpose of this study was to investigate what correlations exist between the immunization and personal belief exemption (PBE) rates and selected characteristics of Arizona schools. The demographic information of a school's student body, the percentage of student who are on free or reduced lunch, the presence of a Title

The purpose of this study was to investigate what correlations exist between the immunization and personal belief exemption (PBE) rates and selected characteristics of Arizona schools. The demographic information of a school's student body, the percentage of student who are on free or reduced lunch, the presence of a Title I program at the school, the median household income of the zip code the school resides in, and the presence of a school nurse were all compared with immunization and PBE rates. Using data provided by the Arizona Department of Health Services (AZDHS), the National Center for Education Statistics (NCES), and the United States Census Bureau, these factors were investigated for kindergarten and 6th grade students. It was found that a higher percentage of white students in a student body was correlated with an higher rate of PBE and a lower immunization rate for measles, mumps, and rubella (MMR), polio, and hepatitis B. A higher percentage of Hispanic students in a student body was correlated with a lower rate of PBE and a higher immunization rate for measles, mumps, rubella (MMR), polio, and hepatitis B. There was little to no correlation between the percentage of students on free or reduced lunch and immunization or PBE rates. A higher median household income was correlated with a higher rate of PBE in public and private schools. Additionally, the immunization rates at schools with a nurse were significantly higher and the rate of PBE was significantly lower than at schools without a nurse. Finally, schools with a Title I program had mean immunization rates that were significantly higher and a mean PBE rate that was significantly lower than schools that did not have a Title I program.
ContributorsSellers, Abigail Leigh (Author) / Hendrickson, Kirstin (Thesis director) / Lefler, Scott (Committee member) / School of International Letters and Cultures (Contributor) / School of Molecular Sciences (Contributor) / Sandra Day O'Connor College of Law (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
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Description
With the new independence of adulthood, college students are a group susceptible to adopting unsupported, if not harmful, health practices. A survey of Arizona State University undergraduate students (N=200) was conducted to evaluate supplement use, trust in information sources, and beliefs about supplement regulation. Of those who reported using supplements,

With the new independence of adulthood, college students are a group susceptible to adopting unsupported, if not harmful, health practices. A survey of Arizona State University undergraduate students (N=200) was conducted to evaluate supplement use, trust in information sources, and beliefs about supplement regulation. Of those who reported using supplements, college students most frequently received information from friends and family. STEM majors in fields unrelated to health who were taking a supplement were found to be less likely to receive information about the supplement from a medical practitioner than those in health fields or those in non-STEM majors (-26.9%, p=0.018). STEM majors in health-related fields were 15.0% more likely to treat colds and/or cold symptoms with research-supported methods identified from reliable sources, while non-health STEM and non-STEM majors were more likely to take unsupported cold treatments (p=0.010). Surveyed students, regardless of major, also stated they would trust a medical practitioner for supplement advice above other sources (88.0%), and the majority expressed a belief that dietary supplements are approved/regulated by the government (59.8%).
ContributorsPerez, Jacob Tanner (Author) / Hendrickson, Kirstin (Thesis director) / Lefler, Scott (Committee member) / College of Liberal Arts and Sciences (Contributor) / School of Molecular Sciences (Contributor) / Department of Physics (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
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Description
Continuing work has been done on a novel class of anti-cancer drugs employing a vinylogous extended amidine system functionalized into benzimidazole ring. Three new derivatives, utilizing a true sugar mimic at the N1-position, have been synthesized. Compounds 6-amino-1-[2-(2-hydroxyethoxy)ethyl-4-imino-2,5-dimethyl-1H-benzimidazole- 7-one (5), 6-amino-1-[2-(2-hydroxysulfonoethoxy)ethyl-4-imino-2,5-dimethyl-1H-benzimidazole-7-one (6), and 6-amino-1-[2-(2-hydroxysulfonoethoxy)ethyl-4-methylimino-2,5-dimethyl-1H-benzimidazole-7-one (7) have been synthesized utilizing similar

Continuing work has been done on a novel class of anti-cancer drugs employing a vinylogous extended amidine system functionalized into benzimidazole ring. Three new derivatives, utilizing a true sugar mimic at the N1-position, have been synthesized. Compounds 6-amino-1-[2-(2-hydroxyethoxy)ethyl-4-imino-2,5-dimethyl-1H-benzimidazole- 7-one (5), 6-amino-1-[2-(2-hydroxysulfonoethoxy)ethyl-4-imino-2,5-dimethyl-1H-benzimidazole-7-one (6), and 6-amino-1-[2-(2-hydroxysulfonoethoxy)ethyl-4-methylimino-2,5-dimethyl-1H-benzimidazole-7-one (7) have been synthesized utilizing similar protocols used in the synthesis of previously screened anti-tumor drugs produced by this laboratory. Compounds (5) and (6) have undergone screening similar to the National Cancer Institute’s (NCIs) Developmental Therapeutic Program (DTP), performed by Dr. Dan LaBarbera at the University of Boston. Both compounds show high cytotoxicity, with complete cell death at 5 µM and bioactive concentrations in the low nanomolar concentrations; more complete data is forthcoming. The proposed mechanism of action is through inhibition of p90RSK 1-2 which is responsible for the phosphorylation of Bcl-2 associated death promoter (BAD), a key metabolite in directing the onset of apoptosis. Future directions of next generation derivatives include modifying the 2-position of the benzimidazole ring into a halogenating or alkylating agent and possibly replacing the methanesulfonate with a phosphate group. This research is being published in the Journal of Medicinal Chemistry.
ContributorsMorrison, Zachary Tyler (Author) / Skibo, Edward (Thesis director) / Lefler, Scott (Committee member) / Barrett, The Honors College (Contributor) / Department of Chemistry and Biochemistry (Contributor)
Created2014-05
Description
Spending time outdoors can have a positive impact on the physical and mental health of individuals. These physiological and psychological benefits were comprehensively reviewed, accompanied by a brief history of these views in American society and how modern programs are promoting outdoor activity. Some of the populations targeted in this

Spending time outdoors can have a positive impact on the physical and mental health of individuals. These physiological and psychological benefits were comprehensively reviewed, accompanied by a brief history of these views in American society and how modern programs are promoting outdoor activity. Some of the populations targeted in this research include children, veterans, the elderly, and the clinically ill. A guidebook for Arizona outdoor adventures \u2014 containing original landscape photography \u2014 was created to encourage ASU students to explore local hikes, campsites, and other outdoor opportunities near the city of Phoenix. Each entry contained a brief description of the area or trail, along with the distance from the ASU Tempe campus and information on the length and difficulty of the hike, if applicable. A section at the end of the book was aimed at education readers on basic outdoor survival protocol, as many people venture into the wild with very little understanding of the dangers associated with their activities. A website was made that mirrors the guidebook, but was intended to be a more accessible method of sharing our information. The final component of the project involved maintaining a social media account over the course of the year, allowing us to expand our reach to people beyond ASU and this community. Over the course of the project, the account gained a large following, and several posted photos went on to be featured on prominent regional accounts. By combining the four components described previously, several resources were created for people, particularly students attending ASU, to gain a better understanding of the outdoor adventures available to them, and the benefits that spending time surrounded by nature can have.
ContributorsSwitzer, Hannah (Co-author) / Weinstein, Casey (Co-author) / Smith, Andrew (Thesis director) / Lefler, Scott (Committee member) / Kozakiewicz, Scott (Committee member) / Harrington Bioengineering Program (Contributor) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2017-05
Description
Each family approaches a cancer diagnosis differently. While some families pursue traditional treatments to the fullest extent, others attempt to refuse chemotherapy, often in favor of alternative medicines. When the patient is a minor, his or her parents have the authority to make medical decisions on their behalf, and this

Each family approaches a cancer diagnosis differently. While some families pursue traditional treatments to the fullest extent, others attempt to refuse chemotherapy, often in favor of alternative medicines. When the patient is a minor, his or her parents have the authority to make medical decisions on their behalf, and this authority is constitutionally protected and socially upheld. However, when the decision to forgo chemotherapy does not comply with minimum standard of care and puts the minor's life in danger, legal action can and has been taken to force the minor to undergo chemotherapy. Legal precedent and biomedical ethics principles guide the decision-making process of the physicians and judges involved, although there is no official framework by which to prioritize these principles. Neglect and abuse procedures, as well as capacity determinations, mature minor doctrines, and religious convictions, add complexity to each forced chemotherapy case. These complexities were explored through the context of four case studies: Cassandra Callendar, who was not granted mature minor status and was forced into treatment by the Connecticut Supreme court; Starchild Abraham Cherrix, who was allowed to pursue the alternative Hoxsey therapy with the consent of his parents and the local court; Dennis Lindberg, a 14-year-old Jehovah's Witness who was permitted to refuse blood transfusions under the Mature Minor Doctrine; and Daniel Hauser, a developmentally delayed teen who was forced to undergo therapy against his parents' religious convictions. In the analysis and comprehensive comparison of these cases, it was concluded that an attempt to establish a protocol by which to determine the ethics of forcing chemotherapy, while well-intended, would ultimately be ineffective and extremely complex. Thus, each forced chemotherapy case must be evaluated on an individual basis.
ContributorsNelson, Sarah Gabrielle (Author) / Hendrickson, Kirstin (Thesis director) / Lynch, John (Committee member) / Jaramillo, Andres (Committee member) / School of Molecular Sciences (Contributor) / Sanford School of Social and Family Dynamics (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
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Description

There is a higher incidence of asthma, worse outcomes, and a higher burden of disease in Black Americans compared to white Americans. This thesis aims to understand asthma disparities in the Black population by analyzing a variety of social determinants of health and genetic factors that may contribute to these

There is a higher incidence of asthma, worse outcomes, and a higher burden of disease in Black Americans compared to white Americans. This thesis aims to understand asthma disparities in the Black population by analyzing a variety of social determinants of health and genetic factors that may contribute to these racial health disparities. Based on the evidence collected, a variety of interventions are discussed that explore potential solutions to address the critical issue.

ContributorsHaldorsen, Kamilla (Author) / Lynch, John (Thesis director) / Hendrickson, Kirstin (Committee member) / Department of Psychology (Contributor) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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Description

Skin cancer diagnoses and deaths continue to increase every year. With basal cell carcinoma (BCC) being the most common type of skin cancer diagnoses, establishing protective measurements against it are important. Surprisingly, sunscreen may not be as effective at protecting against basal cell carcinoma as it is for another non-melanoma

Skin cancer diagnoses and deaths continue to increase every year. With basal cell carcinoma (BCC) being the most common type of skin cancer diagnoses, establishing protective measurements against it are important. Surprisingly, sunscreen may not be as effective at protecting against basal cell carcinoma as it is for another non-melanoma type of skin cancer: squamous cell carcinoma. This paper aims to identify some differences between the two non-melanoma type cancers to find probable reasons sunscreen may be more effective at protecting against one over the other, as well as to find new solutions to protect against basal cell carcinoma. The results conclude that basal cell carcinoma does have UV-induced pathogenesis, in which case sunscreen is protective; however, it also revealed the need for ingredient studies and more sunscreen efficacy studies to determine other BCC pathogenesis pathways. Lastly, aided by dermatologist interviews, current interventions were established in order to provide greater protection against skin cancer. These include reforming the way commercials portray sunscreen to better educate the public about proper application and re-application, genetic testing for high-risk BCC markers, and an emphasis on sun education to the mothers of children.

ContributorsBozzano, Bianca (Author) / Washo-Krupps, Delon (Thesis director) / Hendrickson, Kirstin (Committee member) / Hicks, Andrew (Committee member) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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Description

Peer-reviewed literature on the effects of sound and music on babies ranging from the prenatal period to the postnatal period, called the perinatal period moving forward, is vast. Substantial research has been directed towards the neural connections they make with sound, musical therapy, audio learning, and much more. The primary

Peer-reviewed literature on the effects of sound and music on babies ranging from the prenatal period to the postnatal period, called the perinatal period moving forward, is vast. Substantial research has been directed towards the neural connections they make with sound, musical therapy, audio learning, and much more. The primary focus of this thesis was to review the current literature on how the father's voice affects the fetus during the perinatal period. During the preliminary research of the topic, the process faced an immediate problem as this concept had very little substantial sources. The number of relevant articles or documents with the term “father” in the title can be counted on one hand. In some cases, research that explored the father’s voice did so only as a supporting statistic or comparison to the main goal of exploring the mother’s voice. The mother’s voice has been prioritized as a research topic because of the immediate physical connection between the mother and the child throughout the entire pregnancy. The third semester of pregnancy is often a period of study since what the mother senses, says or does will somehow translate into an experience for the child’s developing brain. On the other hand, the father’s voice has been considered an environmental sound, a position justified by some researchers due to phenomena such as differing levels of fetal attention and observed “preference” of a newborn. The scarcity of research regarding the father’s voice, or the voice of a non-parental male, can be explained in several ways. These include the father’s potential absence due to work, inherited ideologies and biases against active parenting for the father, parental roles, and their unwillingness to utilize infant-directed speech and singing for psychological reasons, during the perinatal period, compared to that of the mother. Researching ways to deepen the relationship between the father and baby during the perinatal period, along with developing new biotechnologies for different kinds of evaluative tests, will help advance the subject matter of how the father’s voice impacts a baby to a larger scale.

ContributorsNguyen, Justin Dinh Huy (Author) / Norton, Kay (Thesis director) / Lefler, Scott (Committee member) / School of Music, Dance and Theatre (Contributor) / School of Molecular Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
Description

Every year, Inflammatory Bowel Disease (IBD) is diagnosed in a growing number of the Americans. Consequently, an extensive amount of research has been dedicated to understanding this disease, and identifying which factors contribute to its symptoms. A large portion of this research has been focused on diet. This paper outlines

Every year, Inflammatory Bowel Disease (IBD) is diagnosed in a growing number of the Americans. Consequently, an extensive amount of research has been dedicated to understanding this disease, and identifying which factors contribute to its symptoms. A large portion of this research has been focused on diet. This paper outlines some of the common diets that are recommended to help those with IBD. The diets discussed are the specific carbohydrate diet, IBD-AID, enteral/parenteral nutrition, low – FODMAP diet, and exclusion diet. It was found that there is a lot of overlap between these diets. Several foods such as corn, dairy, and processed meats were on the avoidance list for more than one diet. Additionally, several diets recommend including probiotic and prebiotic foods each day. From the research gathered in this paper, it is recommended to create an individualized diet with a team of healthcare professionals, using the diets discussed as a guide. While diet is only one of many lifestyle choices that can affect the symptoms of IBD, it is an important one to consider, and can greatly impact the quality of life for patients.

ContributorsAllred, Brandon (Author) / Don, Rachael (Thesis director) / Lefler, Scott (Committee member) / Barrett, The Honors College (Contributor) / Dean, W.P. Carey School of Business (Contributor) / Department of Information Systems (Contributor) / School of Molecular Sciences (Contributor)
Created2023-05
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Description
Inaccuracies and omissions in online science news is a major source of misinformation, with a potentially significant negative impact on the general public. With a vast majority of Americans consuming news through online sources, more research is required on the impact these errors have on the legitimacy of science journalism.

Inaccuracies and omissions in online science news is a major source of misinformation, with a potentially significant negative impact on the general public. With a vast majority of Americans consuming news through online sources, more research is required on the impact these errors have on the legitimacy of science journalism. This study aims to establish baseline methods and measurements for quantification of the accuracy and completeness of online science news articles with respect to both one another and the primary studies upon which they are based. Eleven total outlets and 84 news articles reporting on 14 primary studies were analyzed using both objective and subjective scoring, then normalized and converted to percentages. Results showed a per-outlet normalized objective score range of 58-85.1%, and a per-outlet normalized subjective score range of 32.5-100%. The two highest overall (combined) scoring outlets were Science Daily and Live Science, and the two lowest overall scoring outlets were the New York Post and The Hill. A frequency distribution of per-article normalized objective scores showed the most common objective score was between 70 and 95%.
ContributorsPuskar, Ryan (Author) / Hendrickson, Kirstin (Thesis director) / Lynch, John (Committee member) / School of Molecular Sciences (Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2020-05