The purpose of this study was to find an appropriate solution in reducing inflammation around the ankle joint for Rheumatoid Arthritis (RA) patients, so they are able to increase their endurance and improve their overall quality of life. RA patients have to deal with a significant amount of complications that include chronic inflammation, continuous pain in their joints, and overwhelming stress. In addition, it is very common for RA patients to develop severe mental issues that only makes matters worse. As a result, it is imperative that treatments are provided to RA patients to improve their current situation. Three devices from the current market, made for reducing inflammation of the ankle, were chosen for evaluating the effectiveness of each device. It was determined that with 95% confidence that the Gonicc Professional Foot Sleeve was the most effective in reducing inflammation. A prototype was developed based on the feedback of the participants. Further improvements, the prototype will be compared against the Gonicc Professional Foot Sleeve to determine which is the best solution to improve millions of RA patients' lives.

Intrauterine devices, or IUDs, are long-lasting forms of birth control that have effectiveness comparable to sterilization, while they can be removed at any time. However, the insertion process can be very painful, especially for individuals who have never given vaginal birth. The most common form of pain management for this procedure is having the patient take an ibuprofen an hour or so before the procedure, but this only helps with cramping afterwards, not the acute pain caused by insertion. Pain, and anxiety and fear regarding potential pain, serve as a barrier between users and this highly effective form of birth control. This report uses COMSOL to model lidocaine diffusion from 4% topical hydrogel into the cervix (the main site of acute pain during IUD insertion) over 180 minutes. The cervix was modeled axisymmetrically, using average experimental values for cervix size. Concentration at four specific probe points were measured over time and compared at different concentrations. A sensitivity analysis was performed by adjusting the diffusion coefficient of the epithelial layer. This model was developed to serve as a predictor for future drug applications across the cervix, to determine in advance whether a novel formulation of drug would be effective to significantly reduce pain. This model may be refined further with experimental values for the constants, and with further testing of different lidocaine concentrations.

Pelvic organ prolapse (POP) is a condition involving the weakening of the pelvic floor, with a prevalence of up to 50% of women experiencing the condition to some degree. Individuals with the condition are susceptible to multiple symptoms include vaginal protrusion, dyspareunia, and difficulties with waste excretion. Risk factors are common and numerous for POP, and the economic burden of the condition poses a significant cost to nations worldwide. For many years, the primary solution to POP was the usage of transvaginal meshes, often composed of polypropylene, but rising reports of harmful side effects have led to their recall. Due to this, the space is open for novel solutions, and treatments based in regenerative medicine are on the rise. One such potential treatment is the usage of functionalized polyvinyl alcohol scaffolds to support the regeneration and strengthening of the pelvic floor. To validate the usage of this scaffold, this study focuses on the biocompatibility of the scaffolds, with specific focus on the maintenance of cell viability and proliferation on the scaffold. Through usage of metabolic assays and fluorescence microscopy, scaffolds composed of functional polyvinyl alcohol with cellulose have shown promise in supporting the cell types necessary for reconstructing the pelvic floor.

Phoenix Police officers are required to wear Body-Worn Cameras while out on patrol and must have the cameras turned on when interacting with the public. The Body-Worn Camera (BWC) Policy was initially established as a means of accruing evidence and increasing police accountability when in the presence of the public. However, BWC technology has the ability to perform many other useful functions. The information provided by the cameras could be used to reduce the paperwork done by police officers while on duty, thus allowing them to spend more time taking calls from dispatch. The versatility of the body-worn camera and its components also make it an ideal pairing for an electrocardiograph (ECG) device to aid in the health of officers and law enforcement retention.

Health service quality is understood to be a crucial determinant in successful patient-physician encounters and patient health. One common feeling that patients have reported experiencing during appointments is shame. We hypothesized that patients who experience appearance-based shame during an appointment are not likely to return to the same physician and that patients who do not experience appearance-based shame are likely to return to the same physician. This was assessed by conducting an anonymous online survey of 13 questions that served to establish a general foundation for understanding the participants' physical characteristics such as race, age, weight, and gender identity as well as their overall patient-physician relationship and experiences of shame, if applicable. 119 participants were recruited from Arizona State University and a case study was performed individually for five participants of interest. The data analyzed from this study suggests that while appearance-based shame does exist in healthcare spaces, it is not a significant determining factor in patients returning to their physicians. In addition, there was no significant evidence to suggest that patients who do not experience appearance-based shame are either likely or more likely to return to their physician. We hypothesize this could be due to confounding variables such as convenience, accessibility, or insurance limitations which patients may prioritize over feeling ashamed during an appointment. However, more research needs to be conducted to confirm these hypotheses.

Sensorimotor adaptation is a type of learning that allows sustaining accurate movements by adjusting motor output. This allows the brain to adapt to temporary changes when engaged in a certain task. Within sensorimotor adaptation, visuomotor adaptation (VMA) is one’s ability to correct a visual perturbation. In this study, we present preliminary results on the effects of VMA with the control group, compared to groups undergoing trigeminal nerve stimulation (TNS) or SHAM (placebo) effects. Twenty-two healthy subjects with no past medical history participated in this study. Subjects performed a visuomotor rotation task, which required gradually adapting to a perturbation between hand motion and corresponding visual feedback. Five total blocks were completed: two familiarization blocks, one baseline block, one rotation block with a 30◦ counterclockwise rotation, and one washout block with no rotation. The control group performed better than the 120 Hz (TNS) and SHAM groups due to less directional error (DE) on the respective learning curves. Additionally, the control group adapted faster (less DE) than the SHAM groups that either felt stimulation, or did not feel the stimulation. The results yield new information regarding VMA which can be used in the future when comparing sensorimotor adaptation and its many applications.