Matching Items (5)
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Description
Eosinophilic Esophagitis (EoE) is a chronic autoimmune disease that causes inflammation of the esophagus due to food allergy. In pediatric EoE, remission can be reduced by 95% through the use of hypoallergenic amino acid formulas (AAF), however its bitter taste gives it poor palatability, making nutrition difficult. This thesis highlights

Eosinophilic Esophagitis (EoE) is a chronic autoimmune disease that causes inflammation of the esophagus due to food allergy. In pediatric EoE, remission can be reduced by 95% through the use of hypoallergenic amino acid formulas (AAF), however its bitter taste gives it poor palatability, making nutrition difficult. This thesis highlights the problem of poor palatability of AAF's and explores the idea of prototyping a new flavor enhanced recipe to minimize bitterness for EoE patients and how to evaluate it through sensory evaluation practices. Along the way, I also discovered that quail egg homogenate has novel therapeutic potential to reduce EoE symptoms.
ContributorsBorah, Priya Anjali (Co-author) / Holmes, Katherine (Co-author) / Serrano, Osvin (Co-author) / Spackman, Christy (Thesis director) / Schroeder, Shauna (Committee member) / Harrington Bioengineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2020-12
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Description
With an ever-increasing diagnosis rate and no universal cure, eosinophilic esophagitis (EoE) lacks conclusive data regarding the onset of its autoimmune response and its preferred relation to assigned sex males. This thesis seeks to analyze the effects that assigned sex and determinants of health have on EoE diagnosis through previous

With an ever-increasing diagnosis rate and no universal cure, eosinophilic esophagitis (EoE) lacks conclusive data regarding the onset of its autoimmune response and its preferred relation to assigned sex males. This thesis seeks to analyze the effects that assigned sex and determinants of health have on EoE diagnosis through previous research and survey development. Upon constructing a Qualtrics survey to collect data patterns and trends of subjects diagnosed with this autoimmune disorder, COVID-19 created a halt in its distribution and data collection. This unexpected event led to the collection and compilation of pre-existing research to be implemented into this thesis as a substitute. The key results of this thesis revealed that in twenty research studies regarding sex differences in EoE, at least 70% of patients diagnosed with EoE were male (Liacouras, 2005). With inconclusive results as to why males are diagnosed at a higher rate, results have not confirmed if this percentage ratio is due to social or genetic factors. To conclude, males are predominately diagnosed with EoE in comparison to the female and intersex population, however, with no data currently available on the effects that EoE has on intersex humans, it cannot be determined what factors create this recurring pattern.
ContributorsHolmes, Katherine Elizabeth (Co-author) / Serrano, Osvin (Co-author) / Borah, Priyah (Co-author) / Spackman, Christy (Thesis director) / Schroeder, Shauna (Committee member) / School of Human Evolution & Social Change (Contributor) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2020-12
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Description

Eosinophilic Esophagitis, EoE, is a newer autoimmune chronic esophageal inflammatory illness that results from food allergen triggers (Lucendo, 2017). EoE has created a wide range of diagnostic challenges for physicians because of the similarities that it has compared to gastroesophageal reflux disease, GERD. Current research indicates that EoE predominately impacts

Eosinophilic Esophagitis, EoE, is a newer autoimmune chronic esophageal inflammatory illness that results from food allergen triggers (Lucendo, 2017). EoE has created a wide range of diagnostic challenges for physicians because of the similarities that it has compared to gastroesophageal reflux disease, GERD. Current research indicates that EoE predominately impacts males at higher rates compared to females, while White males are most affected by and at risk for developing EoE compared to people of other racial and ethnic backgrounds (Sperry, 2012). Despite these findings, there continues to be an absence of research on social factors and identities like gender, race, ethnicity, income, sexuality and more, that are neglected in understanding how these features interact with EoE. Thus, the purpose of this thesis was to provide more evidence on identity and social aspects in relation to EoE that remain ignored and explain why there might be difficulties in investigating these topics. Moreover, a survey was also developed in order to better understand the current EoE population between the ages of 18 to 26, in which the transition from pediatric to adult care occurs. Language has been shown to affect patient’s care and treatment regarding their health because of discriminations that patients have been subjected to in the past. Therefore, it is important to discuss the role played by language and political correctness, especially within surveys. This thesis will explore the depth of study that has been completed within neglected areas of research surrounding marginalized communities, while providing new insights and questions for future possible research regarding EoE. This will be accomplished by discussing the existing problems within each topic and draw conclusions as to why EoE research may have been hindered within these neglected subjects. This project will provide a literature review, survey development, and language strategies for conducting inclusive and diverse populations and research topics centered around EoE.

ContributorsSerrano, Osvin (Author) / Spackman, Christy (Thesis director) / Schroeder, Shauna (Committee member) / School of Art (Contributor) / School of Politics and Global Studies (Contributor) / School of Life Sciences (Contributor) / School of Human Evolution & Social Change (Contributor) / Barrett, The Honors College (Contributor)
Created2020-12
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Description

This Project Report documents the accomplishments of an extraordinary group of students, faculty, and staff at the Arizona state University, who participated in a year-long, multidisciplinary, first-of-its-kind academic endeavor entitled “The Making of a COVID Lab.” The lab that is the focus of this project is the ASU Biodesign Clinical

This Project Report documents the accomplishments of an extraordinary group of students, faculty, and staff at the Arizona state University, who participated in a year-long, multidisciplinary, first-of-its-kind academic endeavor entitled “The Making of a COVID Lab.” The lab that is the focus of this project is the ASU Biodesign Clinical Testing Laboratory, known simply as the ABCTL.

ContributorsCompton, Carolyn C. (Project director) / Christianson, Serena L. (Project director) / Floyd, Christopher (Project director) / Schneller, Eugene S (Research team head) / Rigoni, Adam (Research team head) / Stanford, Michael (Research team head) / Cheong, Pauline (Research team head) / McCarville, Daniel R. (Research team head) / Dudley, Sean (Research team head) / Blum, Nita (Research team head) / Magee, Mitch (Research team head) / Agee, Claire (Research team member) / Cosgrove, Samuel (Research team member) / English, Corinne (Research team member) / Mattson, Kyle (Research team member) / Qian, Michael (Research team member) / Espinoza, Hale Anna (Research team member) / Filipek, Marina (Research team member) / Jenkins, Landon James (Research team member) / Ross, Nathaniel (Research team member) / Salvatierra, Madeline (Research team member) / Serrano, Osvin (Research team member) / Wakefield, Alex (Research team member) / Calo, Van Dexter (Research team member) / Nofi, Matthew (Research team member) / Raymond, Courtney (Research team member) / Barwey, Ishna (Research team member) / Bruner, Ashley (Research team member) / Hymer, William (Research team member) / Krell, Abby Elizabeth (Research team member) / Lewis, Gabriel (Research team member) / Myers, Jack (Research team member) / Ramesh, Frankincense (Research team member) / Reagan, Sage (Research team member) / Kandan, Mani (Research team member) / Knox, Garrett (Research team member) / Leung, Michael (Research team member) / Schmit, Jacob (Research team member) / Woo, Sabrina (Research team member) / Anderson, Laura (Research team member) / Breshears, Scott (Research team member) / Majhail, Kajol (Research team member) / Ruan, Ellen (Research team member) / Smetanick, Jennifer (Research team member) / Bardfeld, Sierra (Research team member) / Cura, Joriel (Research team member) / Dholaria, Nikhil (Research team member) / Foote, Hannah (Research team member) / Liu, Tara (Research team member) / Raymond, Julia (Research team member) / Varghese, Mahima (Research team member)
Created2021
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Description
Providing adequate resources for undergraduate students’ career development has been of utmost importance to meet demands from national agencies and industry leaders. At Arizona State University, the size of the undergraduate populations in the School of Life Sciences (SOLS) grew from 1,591 to 3,661, an increase of over 130%

Providing adequate resources for undergraduate students’ career development has been of utmost importance to meet demands from national agencies and industry leaders. At Arizona State University, the size of the undergraduate populations in the School of Life Sciences (SOLS) grew from 1,591 to 3,661, an increase of over 130% from 2003-2017. As of December 19, 2019, SOLS hosted a record 5,318 undergraduate majors on campus and 1,646 students in its online biological sciences program. This steady increase in life science undergraduate student enrollment at ASU attested to the need for appropriate career development education to be woven into the curriculum. Under the framework of higher education’s purpose to provide adequate resources for career success, a career development intervention was designed and implemented as a career planning course for life science students. The purpose of this project was to provide a continuum of job and career information to SOLS’ students to ensure they had appropriate, comprehensive information as they learned about and considered various career opportunities in the life sciences. Three theoretical perspectives guided the research project: Holland’s (1985, 1997) theory of vocational personalities and their connections to work environments, Sampson, Peterson, Reardon and Lenz’s (2003) cognitive information processing career decision theory (CIP), and Bandura’s (1986) self-efficacy theory. Survey results showed increases in all seven constructs—knowledge of career exploration and development tasks, perception of possible professional and career goals and opportunities, goal selection, occupational information, problem solving, planning, self-appraisal—over time among the students. Interview data indicated students noted (a) enrollment in the course for reasons such as determining a career choice that met their needs and preferences while managing expectations and pressures from external sources; (b) broadening perceptions of career options, and (c) developing career exploration and planning skills. The success from this discipline-specific career development course was timely because university leaders were seeking solutions to increase students’ career readiness. The discussion focused on complementarity of the data, connections to the extant research, implications for practice and research, personal lessons learned, and a conclusion.
ContributorsChristianson, Serena L. (Author) / Buss, Ray R. (Thesis advisor) / Fong, Raquel (Committee member) / Reardon, Robert (Committee member) / Arizona State University (Publisher)
Created2021