This paper explores the well-known Atkins Diet, as it also places a strong regulation on macromolecule consumption, specifically carbohydrates, in order to assist with the weight loss process. A review of available literature will be used to investigate: the history of the diet, necessity of macromolecule consumption, the impact this has on the individual biochemical pathways (glycolysis/gluconeogenesis) and the microbiome as a whole, as well as overall success rates and long-term health complications/benefits. Additionally personal statements from various individuals who have experience with the diet, myself included, will be incorporated into a holistic analysis of the effectiveness and longevity of the Atkins weight-loss strategy.