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This is a study of scientific realism, and of the extent to which it is undermined by objections that have been raised by advocates of various forms of antirealism. I seek to develop and present a version of scientific realism that improves on past formulations, and then to show that

This is a study of scientific realism, and of the extent to which it is undermined by objections that have been raised by advocates of various forms of antirealism. I seek to develop and present a version of scientific realism that improves on past formulations, and then to show that standard antirealist arguments against it do not succeed. In this paper, I will first present my formulation of scientific realism, which conceives of theories as model-based and as fundamentally non-linguistic. I advocate an epistemic position that accords with indirect realism, and I review and assess the threat posed by theses of underdetermination. Next, I review and discuss three important views: the antirealist constructivist view of Thomas Kuhn, the realist view of Norwood Hanson, and the antirealist constructive empiricist view of Bas van Fraassen. I find merits and flaws in all three views. In the course of those discussions, I develop the theme that antirealists' arguments generally depend on assumptions that are open to question, especially from the perspective of the version of realism I advocate. I further argue that these antirealist views are undermined by their own tacit appeals to realism.
ContributorsNovack, Alexander Dion (Author) / Armendt, Brad (Thesis advisor) / Creath, Richard (Committee member) / French, Peter (Committee member) / Arizona State University (Publisher)
Created2013
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Description
The academic literature on science communication widely acknowledges a problem: science communication between experts and lay audiences is important, but it is not done well. General audience popular science books, however, carry a reputation for clear science communication and are understudied in the academic literature. For this doctoral dissertation, I

The academic literature on science communication widely acknowledges a problem: science communication between experts and lay audiences is important, but it is not done well. General audience popular science books, however, carry a reputation for clear science communication and are understudied in the academic literature. For this doctoral dissertation, I utilize Sam Harris's The Moral Landscape, a general audience science book on the particularly thorny topic of neuroscientific approaches to morality, as a case-study to explore the possibility of using general audience science books as models for science communication more broadly. I conduct a literary analysis of the text that delimits the scope of its project, its intended audience, and the domains of science to be communicated. I also identify seven literary aspects of the text: three positive aspects that facilitate clarity and four negative aspects that interfere with lay public engagement. I conclude that The Moral Landscape relies on an assumed knowledge base and intuitions of its audience that cannot reasonably be expected of lay audiences; therefore, it cannot properly be construed as popular science communication. It nevertheless contains normative lessons for the broader science project, both in literary aspects to be salvaged and literary aspects and concepts to consciously be avoided and combated. I note that The Moral Landscape's failings can also be taken as an indication that typical descriptions of science communication offer under-detailed taxonomies of both audiences for science communication and the varieties of science communication aimed at those audiences. Future directions of study include rethinking appropriate target audiences for science literacy projects and developing a more discriminating taxonomy of both science communication and lay publics.
ContributorsJohnson, Nathan W (Author) / Robert, Jason S (Thesis advisor) / Creath, Richard (Committee member) / Martinez, Jacqueline (Committee member) / Sylvester, Edward (Committee member) / Lynch, John (Committee member) / Arizona State University (Publisher)
Created2013
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Once perceived as an unimportant occurrence in living organisms, cell degeneration was reconfigured as an important biological phenomenon in development, aging, health, and diseases in the twentieth century. This dissertation tells a twentieth-century history of scientific investigations on cell degeneration, including cell death and aging. By describing four central developments

Once perceived as an unimportant occurrence in living organisms, cell degeneration was reconfigured as an important biological phenomenon in development, aging, health, and diseases in the twentieth century. This dissertation tells a twentieth-century history of scientific investigations on cell degeneration, including cell death and aging. By describing four central developments in cell degeneration research with the four major chapters, I trace the emergence of the degenerating cell as a scientific object, describe the generations of a variety of concepts, interpretations and usages associated with cell death and aging, and analyze the transforming influences of the rising cell degeneration research. Particularly, the four chapters show how the changing scientific practices about cellular life in embryology, cell culture, aging research, and molecular biology of Caenorhabditis elegans shaped the interpretations about cell degeneration in the twentieth-century as life-shaping, limit-setting, complex, yet regulated. These events created and consolidated important concepts in life sciences such as programmed cell death, the Hayflick limit, apoptosis, and death genes. These cases also transformed the material and epistemic practices about the end of cellular life subsequently and led to the formations of new research communities. The four cases together show the ways cell degeneration became a shared subject between molecular cell biology, developmental biology, gerontology, oncology, and pathology of degenerative diseases. These practices and perspectives created a special kind of interconnectivity between different fields and led to a level of interdisciplinarity within cell degeneration research by the early 1990s.
ContributorsJiang, Lijing (Author) / Maienschein, Jane (Thesis advisor) / Laubichler, Manfred (Thesis advisor) / Hurlbut, James (Committee member) / Creath, Richard (Committee member) / White, Michael (Committee member) / Arizona State University (Publisher)
Created2013
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Description
The present essay addresses the epistemic difficulties involved in achieving consensus with respect to the Hayek-Keynes debate. In particular, it is argued that the debate cannot be settled on the basis of the observable evidence; or, more precisely, that the empirical implications of the theories of Hayek and Keynes are

The present essay addresses the epistemic difficulties involved in achieving consensus with respect to the Hayek-Keynes debate. In particular, it is argued that the debate cannot be settled on the basis of the observable evidence; or, more precisely, that the empirical implications of the theories of Hayek and Keynes are such that, regardless of what is observed, both of the theories can be interpreted as true, or at least, not falsified. Regardless of the evidence, both Hayek and Keynes can be interpreted as right. The underdetermination of theories by evidence is an old and ubiquitous problem in science. The present essay makes explicit the respects in which the empirical evidence underdetermines the choice between the theories of Hayek and Keynes. In particular, it is argued both that there are convenient responses one can offer that protect each theory from what appears to be threatening evidence (i.e., that the choice between the two theories is underdetermined in the holist sense) and that, for particular kinds of evidence, the two theories are empirically equivalent (i.e., with respect to certain kinds of evidence, the choice between the two theories is underdetermined in the contrastive sense).
ContributorsScheall, Scott (Author) / Creath, Richard (Thesis advisor) / Armendt, Brad (Committee member) / French, Peter (Committee member) / Arizona State University (Publisher)
Created2012
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Description
Gays identity is usually cast in generics--statements about an indeterminate number of members in a given category. Sometimes these generic statements often get built up into folk definitions, vague and imprecise ways to talk about objects. Other times generics get co-opted into authentic definitions, definitions that pick out a few

Gays identity is usually cast in generics--statements about an indeterminate number of members in a given category. Sometimes these generic statements often get built up into folk definitions, vague and imprecise ways to talk about objects. Other times generics get co-opted into authentic definitions, definitions that pick out a few traits and assert that real members of the class have these traits and members that do not are simply members by a technicality. I assess how we adopt these generic traits into our language and what are the ramifications of using generic traits as a social identity. I analyze the use of authentic definitions in Queer Theory, particularly Michael Warner's use of authentic traits to define a normative Queer identity. I do not just simply focus on what are the effects, but how these folk or authentic definitions gain currency and, furthermore, how can they be changed. I conclude with an analytic account of what it means to be gay and argue that such an account will undercut many of the problems associated with folk or authentic definitions about being gay.
ContributorsBlankschaen, Kurt (Author) / Calhoun, Cheshire (Thesis advisor) / Pinillos, Angel (Committee member) / Creath, Richard (Committee member) / Arizona State University (Publisher)
Created2012
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Description
In complex consumer-resource type systems, where diverse individuals are interconnected and interdependent, one can often anticipate what has become known as the tragedy of the commons, i.e., a situation, when overly efficient consumers exhaust the common resource, causing collapse of the entire population. In this dissertation I use mathematical modeling

In complex consumer-resource type systems, where diverse individuals are interconnected and interdependent, one can often anticipate what has become known as the tragedy of the commons, i.e., a situation, when overly efficient consumers exhaust the common resource, causing collapse of the entire population. In this dissertation I use mathematical modeling to explore different variations on the consumer-resource type systems, identifying some possible transitional regimes that can precede the tragedy of the commons. I then reformulate it as a game of a multi-player prisoner's dilemma and study two possible approaches for preventing it, namely direct modification of players' payoffs through punishment/reward and modification of the environment in which the interactions occur. I also investigate the questions of whether the strategy of resource allocation for reproduction or competition would yield higher fitness in an evolving consumer-resource type system and demonstrate that the direction in which the system will evolve will depend not only on the state of the environment but largely on the initial composition of the population. I then apply the developed framework to modeling cancer as an evolving ecological system and draw conclusions about some alternative approaches to cancer treatment.
ContributorsKareva, Irina (Author) / Castillo-Chavez, Carlos (Thesis advisor) / Collins, James (Committee member) / Nagy, John (Committee member) / Smith, Hal (Committee member) / Arizona State University (Publisher)
Created2012
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Description
Despite years of effort, the field of conservation biology still struggles to incorporate theories of animal behavior. I introduce in Chapter I the issues surrounding the disconnect between behavioral ecology and conservation biology, and propose the use of behavioral knowledge in population viability analysis. In Chapter II, I develop a

Despite years of effort, the field of conservation biology still struggles to incorporate theories of animal behavior. I introduce in Chapter I the issues surrounding the disconnect between behavioral ecology and conservation biology, and propose the use of behavioral knowledge in population viability analysis. In Chapter II, I develop a framework that uses three strategies for incorporating behavior into demographic models, outline the costs of each strategy through decision analysis, and build on previous work in behavioral ecology and demography. First, relevant behavioral mechanisms should be included in demographic models used for conservation decision-making. Second, I propose rapid behavioral assessment as a useful tool to approximate demographic rates through regression of demographic phenomena on observations of related behaviors. This technique provides behaviorally estimated parameters that may be applied to population viability analysis for use in management. Finally, behavioral indices can be used as warning signs of population decline. The proposed framework combines each strategy through decision analysis to provide quantitative rules that determine when incorporating aspects of conservation behavior may be beneficial to management. Chapter III applies this technique to estimate birthrate in a colony of California sea lions in the Gulf of California, Mexico. This study includes a cost analysis of the behavioral and traditional parameter estimation techniques. I then provide in Chapter IV practical recommendations for applying this framework to management programs along with general guidelines for the development of rapid behavioral assessment.
ContributorsWildermuth, Robert (Author) / Gerber, Leah R. (Thesis advisor) / Collins, James (Committee member) / Smith, Andrew (Committee member) / Arizona State University (Publisher)
Created2012
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Description
Influenza has shown its potential to affect and even kill millions of people within an extremely short time frame, yet studies and surveys show that the general public is not well educated about the facts about influenza, including prevention and treatment. For this reason, public perception of influenza is extremely

Influenza has shown its potential to affect and even kill millions of people within an extremely short time frame, yet studies and surveys show that the general public is not well educated about the facts about influenza, including prevention and treatment. For this reason, public perception of influenza is extremely skewed, with people generally not taking the disease as seriously as they should given its severity. To investigate the inconsistencies between action and awareness of best available knowledge regarding influenza, this study conducted literature review and a survey of university students about their knowledge, perceptions, and action taken in relationship to influenza. Due to their dense living quarters, constant daily interactions, and mindset that they are "immune" to fairly common diseases like influenza, university students are a representative sample of urban populations. According to the World Health Organization (WHO), 54% of the world's population lived in cities as of 2014 (Urban population growth). Between 2015 and 2020, the global urban population is expected to grow 1.84% per year, 1.63% between 2020 and 2025, and 1.44% between 2025 and 2030 (Urban population growth). Similar projections estimate that by 2017, an overwhelming majority of the world's population, even in less developed countries, will be living in cities (Urban population growth). Results of this study suggest possible reasons for the large gap between best available knowledge and the perceptions and actions of individuals on the other hand. This may lead to better-oriented influenza education initiatives, more effective prevention and treatment plans, and generally raise excitement and awareness surrounding public health and scientific communication.
ContributorsGur-Arie, Rachel Ellen Haviva (Author) / Maienschein, Jane (Thesis director) / Laubichler, Manfred (Committee member) / Creath, Richard (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor)
Created2014-12
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Description
Influenza is a viral infection with the potential to infect millions worldwide. In the case of such a pandemic outbreak, direct patient interaction is handled by the medical community, composed of hospitals, medical professionals, and the policies that regulate them. The medical community is responsible not only for treating infected

Influenza is a viral infection with the potential to infect millions worldwide. In the case of such a pandemic outbreak, direct patient interaction is handled by the medical community, composed of hospitals, medical professionals, and the policies that regulate them. The medical community is responsible not only for treating infected individuals, but preventing the spread of influenza to healthy individuals. Given this responsibility, the medical community has drafted preparedness plans laying down guidelines for action in the case of an influenza pandemic. This project reviewed these preparedness plans for hospitals in Arizona as well as reviewing the literature produced by the Department of Health and Human Services to guide these plans. The review revealed that the medical community is woefully unprepared to handle the number of infected individuals, projected to be close to 90 million. Plans are disorganized, outdated, and nonexistent. The conclusions of this thesis offer suggestions for pandemic policy improvement.
ContributorsAbboud, Alexis J (Author) / Maienschein, Jane (Thesis director) / Creath, Richard (Committee member) / O'Neil, Erica (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor)
Created2014-05
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Description
Conservation is a complicated entity consisting of a multitude of professional fields including social issues, cultural issues, and physical science. This thesis evaluates the positive and negative aspects of two broad types of conservation: top down fortress conservation and bottom up community-based conservation. Fortress conservation has many negative aspects, such

Conservation is a complicated entity consisting of a multitude of professional fields including social issues, cultural issues, and physical science. This thesis evaluates the positive and negative aspects of two broad types of conservation: top down fortress conservation and bottom up community-based conservation. Fortress conservation has many negative aspects, such as displacing human communities and preventing utilization of resources. However, it also has positive aspects, such as preventing the destruction of delicate ecosystems and slowing down extinctions. Community-based conservation is more inclusive and focuses on including the indigenous populations located within the proposed conservation site in the decision-making process. Its negatives include having an anthropocentric goal instead of valuing nature's intrinsic values. Understanding the differences inherent in these two methods is necessary in order to implement a conservation network with the highest chance for success.
ContributorsFink, Laurel Berylline (Author) / Smith, Andrew (Thesis director) / Collins, James (Committee member) / Minteer, Ben (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor)
Created2014-05