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Continuous advancements in biomedical research have resulted in the production of vast amounts of scientific data and literature discussing them. The ultimate goal of computational biology is to translate these large amounts of data into actual knowledge of the complex biological processes and accurate life science models. The ability to

Continuous advancements in biomedical research have resulted in the production of vast amounts of scientific data and literature discussing them. The ultimate goal of computational biology is to translate these large amounts of data into actual knowledge of the complex biological processes and accurate life science models. The ability to rapidly and effectively survey the literature is necessary for the creation of large scale models of the relationships among biomedical entities as well as hypothesis generation to guide biomedical research. To reduce the effort and time spent in performing these activities, an intelligent search system is required. Even though many systems aid in navigating through this wide collection of documents, the vastness and depth of this information overload can be overwhelming. An automated extraction system coupled with a cognitive search and navigation service over these document collections would not only save time and effort, but also facilitate discovery of the unknown information implicitly conveyed in the texts. This thesis presents the different approaches used for large scale biomedical named entity recognition, and the challenges faced in each. It also proposes BioEve: an integrative framework to fuse a faceted search with information extraction to provide a search service that addresses the user's desire for "completeness" of the query results, not just the top-ranked ones. This information extraction system enables discovery of important semantic relationships between entities such as genes, diseases, drugs, and cell lines and events from biomedical text on MEDLINE, which is the largest publicly available database of the world's biomedical journal literature. It is an innovative search and discovery service that makes it easier to search
avigate and discover knowledge hidden in life sciences literature. To demonstrate the utility of this system, this thesis also details a prototype enterprise quality search and discovery service that helps researchers with a guided step-by-step query refinement, by suggesting concepts enriched in intermediate results, and thereby facilitating the "discover more as you search" paradigm.
ContributorsKanwar, Pradeep (Author) / Davulcu, Hasan (Thesis advisor) / Dinu, Valentin (Committee member) / Li, Baoxin (Committee member) / Arizona State University (Publisher)
Created2010
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Description
As a promising solution to the problem of acquiring and storing large amounts of image and video data, spatial-multiplexing camera architectures have received lot of attention in the recent past. Such architectures have the attractive feature of combining a two-step process of acquisition and compression of pixel measurements in a

As a promising solution to the problem of acquiring and storing large amounts of image and video data, spatial-multiplexing camera architectures have received lot of attention in the recent past. Such architectures have the attractive feature of combining a two-step process of acquisition and compression of pixel measurements in a conventional camera, into a single step. A popular variant is the single-pixel camera that obtains measurements of the scene using a pseudo-random measurement matrix. Advances in compressive sensing (CS) theory in the past decade have supplied the tools that, in theory, allow near-perfect reconstruction of an image from these measurements even for sub-Nyquist sampling rates. However, current state-of-the-art reconstruction algorithms suffer from two drawbacks -- They are (1) computationally very expensive and (2) incapable of yielding high fidelity reconstructions for high compression ratios. In computer vision, the final goal is usually to perform an inference task using the images acquired and not signal recovery. With this motivation, this thesis considers the possibility of inference directly from compressed measurements, thereby obviating the need to use expensive reconstruction algorithms. It is often the case that non-linear features are used for inference tasks in computer vision. However, currently, it is unclear how to extract such features from compressed measurements. Instead, using the theoretical basis provided by the Johnson-Lindenstrauss lemma, discriminative features using smashed correlation filters are derived and it is shown that it is indeed possible to perform reconstruction-free inference at high compression ratios with only a marginal loss in accuracy. As a specific inference problem in computer vision, face recognition is considered, mainly beyond the visible spectrum such as in the short wave infra-red region (SWIR), where sensors are expensive.
ContributorsLohit, Suhas Anand (Author) / Turaga, Pavan (Thesis advisor) / Spanias, Andreas (Committee member) / Li, Baoxin (Committee member) / Arizona State University (Publisher)
Created2015
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Description
In UAVs and parking lots, it is typical to first collect an enormous number of pixels using conventional imagers. This is followed by employment of expensive methods to compress by throwing away redundant data. Subsequently, the compressed data is transmitted to a ground station. The past decade has seen the

In UAVs and parking lots, it is typical to first collect an enormous number of pixels using conventional imagers. This is followed by employment of expensive methods to compress by throwing away redundant data. Subsequently, the compressed data is transmitted to a ground station. The past decade has seen the emergence of novel imagers called spatial-multiplexing cameras, which offer compression at the sensing level itself by providing an arbitrary linear measurements of the scene instead of pixel-based sampling. In this dissertation, I discuss various approaches for effective information extraction from spatial-multiplexing measurements and present the trade-offs between reliability of the performance and computational/storage load of the system. In the first part, I present a reconstruction-free approach to high-level inference in computer vision, wherein I consider the specific case of activity analysis, and show that using correlation filters, one can perform effective action recognition and localization directly from a class of spatial-multiplexing cameras, called compressive cameras, even at very low measurement rates of 1\%. In the second part, I outline a deep learning based non-iterative and real-time algorithm to reconstruct images from compressively sensed (CS) measurements, which can outperform the traditional iterative CS reconstruction algorithms in terms of reconstruction quality and time complexity, especially at low measurement rates. To overcome the limitations of compressive cameras, which are operated with random measurements and not particularly tuned to any task, in the third part of the dissertation, I propose a method to design spatial-multiplexing measurements, which are tuned to facilitate the easy extraction of features that are useful in computer vision tasks like object tracking. The work presented in the dissertation provides sufficient evidence to high-level inference in computer vision at extremely low measurement rates, and hence allows us to think about the possibility of revamping the current day computer systems.
ContributorsKulkarni, Kuldeep Sharad (Author) / Turaga, Pavan (Thesis advisor) / Li, Baoxin (Committee member) / Chakrabarti, Chaitali (Committee member) / Sankaranarayanan, Aswin (Committee member) / LiKamWa, Robert (Committee member) / Arizona State University (Publisher)
Created2017
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Description
Compressive sensing theory allows to sense and reconstruct signals/images with lower sampling rate than Nyquist rate. Applications in resource constrained environment stand to benefit from this theory, opening up many possibilities for new applications at the same time. The traditional inference pipeline for computer vision sequence reconstructing the image from

Compressive sensing theory allows to sense and reconstruct signals/images with lower sampling rate than Nyquist rate. Applications in resource constrained environment stand to benefit from this theory, opening up many possibilities for new applications at the same time. The traditional inference pipeline for computer vision sequence reconstructing the image from compressive measurements. However,the reconstruction process is a computationally expensive step that also provides poor results at high compression rate. There have been several successful attempts to perform inference tasks directly on compressive measurements such as activity recognition. In this thesis, I am interested to tackle a more challenging vision problem - Visual question answering (VQA) without reconstructing the compressive images. I investigate the feasibility of this problem with a series of experiments, and I evaluate proposed methods on a VQA dataset and discuss promising results and direction for future work.
ContributorsHuang, Li-Chin (Author) / Turaga, Pavan (Thesis advisor) / Yang, Yezhou (Committee member) / Li, Baoxin (Committee member) / Arizona State University (Publisher)
Created2017
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Description
Over the last decade, deep neural networks also known as deep learning, combined with large databases and specialized hardware for computation, have made major strides in important areas such as computer vision, computational imaging and natural language processing. However, such frameworks currently suffer from some drawbacks. For example, it is

Over the last decade, deep neural networks also known as deep learning, combined with large databases and specialized hardware for computation, have made major strides in important areas such as computer vision, computational imaging and natural language processing. However, such frameworks currently suffer from some drawbacks. For example, it is generally not clear how the architectures are to be designed for different applications, or how the neural networks behave under different input perturbations and it is not easy to make the internal representations and parameters more interpretable. In this dissertation, I propose building constraints into feature maps, parameters and and design of algorithms involving neural networks for applications in low-level vision problems such as compressive imaging and multi-spectral image fusion, and high-level inference problems including activity and face recognition. Depending on the application, such constraints can be used to design architectures which are invariant/robust to certain nuisance factors, more efficient and, in some cases, more interpretable. Through extensive experiments on real-world datasets, I demonstrate these advantages of the proposed methods over conventional frameworks.
ContributorsLohit, Suhas Anand (Author) / Turaga, Pavan (Thesis advisor) / Spanias, Andreas (Committee member) / Li, Baoxin (Committee member) / Jayasuriya, Suren (Committee member) / Arizona State University (Publisher)
Created2019
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Description
A massive volume of data is generated at an unprecedented rate in the information age. The growth of data significantly exceeds the computing and storage capacities of the existing digital infrastructure. In the past decade, many methods are invented for data compression, compressive sensing and reconstruction, and compressed learning (learning

A massive volume of data is generated at an unprecedented rate in the information age. The growth of data significantly exceeds the computing and storage capacities of the existing digital infrastructure. In the past decade, many methods are invented for data compression, compressive sensing and reconstruction, and compressed learning (learning directly upon compressed data) to overcome the data-explosion challenge. While prior works are predominantly model-based, focus on small models, and not suitable for task-oriented sensing or hardware acceleration, the number of available models for compression-related tasks has escalated by orders of magnitude in the past decade. Motivated by this significant growth and the success of big data, this dissertation proposes to revolutionize both the compressive sensing reconstruction (CSR) and compressed learning (CL) methods from the data-driven perspective. In this dissertation, a series of topics on data-driven CSR are discussed. Individual data-driven models are proposed for the CSR of bio-signals, images, and videos with improved compression ratio and recovery fidelity trade-off. Specifically, a scalable Laplacian pyramid reconstructive adversarial network (LAPRAN) is proposed for single-image CSR. LAPRAN progressively reconstructs images following the concept of the Laplacian pyramid through the concatenation of multiple reconstructive adversarial networks (RANs). For the CSR of videos, CSVideoNet is proposed to improve the spatial-temporal resolution of reconstructed videos. Apart from CSR, data-driven CL is discussed in the dissertation. A CL framework is proposed to extract features directly from compressed data for image classification, objection detection, and semantic/instance segmentation. Besides, the spectral bias of neural networks is analyzed from the frequency perspective, leading to a learning-based frequency selection method for identifying the trivial frequency components which can be removed without accuracy loss. Compared with the conventional spatial downsampling approaches, the proposed frequency-domain learning method can achieve higher accuracy with reduced input data size. The methodologies proposed in this dissertation are not restricted to the above-mentioned applications. The dissertation also discusses other potential applications and directions for future research.
ContributorsXu, Kai (Author) / Ren, Fengbo (Thesis advisor) / Li, Baoxin (Committee member) / Turaga, Pavan (Committee member) / Yang, Yezhou (Committee member) / Arizona State University (Publisher)
Created2021