Matching Items (15)
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- Creators: FitzPatrick, Carole
Description
Libby Larsen is one of the most performed and acclaimed composers today. She is a spirited, compelling, and sensitive composer whose music enhances the poetry of America's most prominent authors. Notable among her works are song cycles for soprano based on the poetry of female writers, among them novelist and poet Willa Cather (1873-1947). Larsen has produced two song cycles on works from Cather's substantial output of fiction: one based on Cather's short story, "Eric Hermannson's Soul," titled Margaret Songs: Three Songs from Willa Cather (1996); and later, My Antonia (2000), based on Cather's novel of the same title. In Margaret Songs, Cather's poetry and short stories--specifically the character of Margaret Elliot--combine with Larsen's unique compositional style to create a surprising collaboration. This study explores how Larsen in these songs delves into the emotional and psychological depths of Margaret's character, not fully formed by Cather. It is only through Larsen's music and Cather's poetry that Margaret's journey through self-discovery and love become fully realized. This song cycle is a glimpse through the eyes of two prominent female artists on the societal pressures placed upon Margaret's character, many of which still resonate with women in today's culture. This study examines the work Margaret Songs by discussing Willa Cather, her musical influences, and the conditions surrounding the writing of "Eric Hermannson's Soul." It looks also into Cather's influence on Libby Larsen and the commission leading to Margaret Songs. Finally, a description of the musical, dramatic, and textual content of the songs completes this interpretation of the interactions of Willa Cather, Libby Larsen, and the character of Margaret Elliot.
ContributorsMcLain, Christi Marie (Author) / FitzPatrick, Carole (Thesis advisor) / Dreyfoos, Dale (Committee member) / Holbrook, Amy (Committee member) / Ryan, Russell (Committee member) / Arizona State University (Publisher)
Created2013
ContributorsFitzPatrick, Carole (Performer) / Ryan, Russell (Performer) / ASU Library. Music Library (Publisher)
Created2018-10-14
Description
Each year, 30,000 patients obtain transplants. To prevent graft rejection, immunosuppressants such as tacrolimus are prescribed. Due to tacrolimus's narrow therapeutic range, a dose that is too low places patients at risk for transplant rejection, but too high of a dose leads to kidney failure. The de facto method for monitoring of transplant patient health is bimonthly blood draws, which are cumbersome, painful, and difficult to translate into urgently needed dosage changes in a timely manner. To improve long-term transplant survival rates, we propose a finger-prick sensor that will provide patients and healthcare providers with a measurement of tacrolimus, immune health (through IL-12), and kidney damage (through cystatin C) levels 100 times more frequently than the status quo. Additionally, patient quality of life will be improved due to reduction in time and pain associated with blood draws. Optimal binding frequencies for each marker were found. However, due to limitations with EIS, the integration of the detection of the three markers into one multimarker sensing platform has not yet been realized. To this end, impedance-time tests were run on each marker along with different antibodies, and optimal times of each marker were determined to be 17s, 6s, and 2s, for tacrolimus, cystatin c, and IL-12, respectively (n=6). The integration of impedance-time analysis with traditional EIS methodologies has the potential to enable multi-marker analysis by analyzing binding kinetics on a single electrode with respect to time. Thus, our results provide unique insight into possibilities to improve and facilitate detection of multiple markers not only for the sensor for solid organ transplant patients, but for the monitoring of patients with disease that also entail the observation of multiple markers. Furthermore, the use of impedance-time testing also provides the ability for another way to optimize accuracy/precision of marker detection because it specifies a particular time, in addition to a particular optimal binding frequency, at which to measure concentration.
ContributorsDoshi, Meera Kshitij (Author) / LaBelle, Jeffrey (Thesis director) / Steidley, Eric (Committee member) / Harrington Bioengineering Program (Contributor) / Sanford School of Social and Family Dynamics (Contributor) / Barrett, The Honors College (Contributor)
Created2017-05
ContributorsFitzPatrick, Carole (Performer) / Ryan, Russell (Performer) / ASU Library. Music Library (Publisher)
Created2017-10-15
ContributorsDeMaris, Brian (Performer) / DeMaris, Amanda (Performer) / Weiss, Stephanie (Performer) / Dreyfoos, Dale (Performer) / FitzPatrick, Carole (Performer) / Pitman, Andrea (Performer) / Yatso, Toby (Performer) / Hawkins, Gordon (Performer) / Sabrowsky, Kaitlyn (Performer) / Bruley, Billie (Performer) / Sadownik, Stephanie (Performer) / Myers, Nathan De' Shon (Performer) / ASU Library. Music Library (Publisher)
Created2022-09-11
ContributorsFitzPatrick, Carole (Performer) / Barefield, Robert (Performer) / Ryan, Russell (Performer) / ASU Library. Music Library (Publisher)
Created2014-03-23
ContributorsHamilton, Robert, 1937- (Performer) / Pagano, Caio, 1940- (Performer) / FitzPatrick, Carole (Performer) / Ryan, Russell (Performer) / ASU Library. Music Library (Publisher)
Created2011-10-21
ContributorsFitzPatrick, Carole (Performer) / Ryan, Russell (Performer) / ASU Library. Music Library (Publisher)
Created2012-09-23
ContributorsFitzPatrick, Carole (Performer) / Ryan, Russell (Performer) / McLin, Katherine (Performer) / ASU Library. Music Library (Publisher)
Created2016-10-16
ContributorsFitzPatrick, Carole (Performer) / Sellheim, Eckart (Performer) / Montilla, Jorge (Performer) / ASU Library. Music Library (Publisher)
Created2006-02-07