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Corporations in biomedicine hold significant power and influence, in both political and personal spheres. The decisions these companies make about ethics are critically important, as they help determine what products are developed, how they are developed, how they are promoted, and potentially even how they are regulated. In the last

Corporations in biomedicine hold significant power and influence, in both political and personal spheres. The decisions these companies make about ethics are critically important, as they help determine what products are developed, how they are developed, how they are promoted, and potentially even how they are regulated. In the last fifteen years, for-profit private companies have been assembling bioethics committees to help resolve dilemmas that require informed deliberation about ethical, legal, scientific, and economic considerations. Private sector bioethics committees represent an important innovation in the governance of emerging technologies, with corporations taking a lead role in deciding what is ethically appropriate or problematic. And yet, we know very little about these committees, including their structures, memberships, mandates, authority, and impact. Drawing on an extensive literature review and qualitative analysis of semi-structured interviews with executives, scientists and board members, this dissertation provides an in-depth analysis of the Ethics and Public Policy Board at SmithKline Beecham, the Ethics Advisory Board at Advanced Cell Technology, and the Bioethics Committee at Eli Lilly and offers insights about how ideas of bioethics and governance are currently imagined and enacted within corporations. The SmithKline Beecham board was the first private sector bioethics committee; its mandate was to explore, in a comprehensive and balanced analysis, the ethics of macro trends in science and technology. The Advanced Cell Technology board was created to be like a watchdog for the company, to prevent them from making major errors. The Eli Lilly board is different than the others in that it is made up mostly of internal employees and does research ethics consultations within the company. These private sector bioethics committees evaluate and construct new boundaries between their private interests and the public values they claim to promote. Findings from this dissertation show that criticisms of private sector bioethics that focus narrowly on financial conflicts of interest and a lack of transparency obscure analysis of the ideas about governance (about expertise, credibility and authority) that emerge from these structures and hamper serious debate about the possible impacts of moving ethical deliberation from the public to the private sector.
ContributorsBrian, Jennifer (Author) / Robert, Jason S (Thesis advisor) / Maienschein, Jane (Committee member) / Hurlbut, James B (Committee member) / Sarewitz, Daniel (Committee member) / Brown, Mark B. (Committee member) / Moreno, Jonathan D. (Committee member) / Arizona State University (Publisher)
Created2012
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Improvised explosive devices (IEDs) have become a major threat to military personnel in recent years. In the United States Army, Mission Payload Operators (MPOs) operate cameras from unmanned aerial vehicles (UAVs) to detect the threat of IEDs using real-time images received. Previous researchers obtained the expert knowledge of twelve MPOs

Improvised explosive devices (IEDs) have become a major threat to military personnel in recent years. In the United States Army, Mission Payload Operators (MPOs) operate cameras from unmanned aerial vehicles (UAVs) to detect the threat of IEDs using real-time images received. Previous researchers obtained the expert knowledge of twelve MPOs at Fort Huachuca and learned that they rely on "behavioral signatures," the behavioral and environmental cues associated with IED threat rather than the IED itself (Cooke, Hosch, Banas, Hunn, Staszewski & Fensterer, 2010). To the best of our knowledge, no formal MPO training exists and all training is acquired on-the-job. The end goal is to create training systems for future MPOs using cognitive engineering based on expert skill (CEBES) that focus on detection of behavioral cues associated with IED threats. The complexity and dynamicity of cues associated with IED emplacement is to be noted, as such cues are influenced by sociocultural knowledge and often develop over significant periods of time. A dynamic full motion video simulation environment has been created, and embedded with cues elicited from expert MPOs. A three-part simulation has been created. The next step is verifying critical cues MPOs identify and focus on using eye tracking equipment.
ContributorsKnobloch, Ashley Kay (Author) / Cooke, Nancy (Thesis director) / Branaghan, Russ (Committee member) / Barrett, The Honors College (Contributor) / School of Nutrition and Health Promotion (Contributor) / Human Systems Engineering (Contributor)
Created2014-12