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Description
Traditional public health strategies for assessing human behavior, exposure, and activity are considered resource-exhaustive, time-consuming, and expensive, warranting a need for alternative methods to enhance data acquisition and subsequent interventions. This dissertation critically evaluated the use of wastewater-based epidemiology (WBE) as an inclusive and non-invasive tool for conducting near real-time

Traditional public health strategies for assessing human behavior, exposure, and activity are considered resource-exhaustive, time-consuming, and expensive, warranting a need for alternative methods to enhance data acquisition and subsequent interventions. This dissertation critically evaluated the use of wastewater-based epidemiology (WBE) as an inclusive and non-invasive tool for conducting near real-time population health assessments. A rigorous literature review was performed to gauge the current landscape of WBE to monitor for biomarkers indicative of diet, as well as exposure to estrogen-mimicking endocrine disrupting (EED) chemicals via route of ingestion. Wastewater-derived measurements of phytoestrogens from August 2017 through July 2019 (n = 156 samples) in a small sewer catchment revealed seasonal patterns, with highest average per capita consumption rates in January through March of each year (2018: 7.0 ± 2.0 mg d-1; 2019: 8.2 ± 2.3 mg d-1) and statistically significant differences (p = 0.01) between fall and winter (3.4 ± 1.2 vs. 6.1 ± 2.9 mg d-1; p ≤ 0.01) and spring and summer (5.6 ± 2.1 vs. 3.4 ± 1.5 mg d-1; p ≤ 0.01). Additional investigations, including a human gut microbial composition analysis of community wastewater, were performed to support a methodological framework for future implementation of WBE to assess population-level dietary behavior. In response to the COVID-19 global pandemic, a high-frequency, high-resolution sample collection approach with public data sharing was implemented throughout the City of Tempe, Arizona, and analyzed for SARS-CoV-2 (E gene) from April 2020 through March 2021 (n = 1,556 samples). Results indicate early warning capability during the first wave (June 2020) compared to newly reported clinical cases (8.5 ± 2.1 days), later transitioning to a slight lagging indicator in December/January 2020-21 (-2.0 ± 1.4 days). A viral hotspot from within a larger catchment area was detected, prompting targeted interventions to successfully mitigate community spread; reinforcing the importance of sample collection within the sewer infrastructure. I conclude that by working in tandem with traditional approaches, WBE can enlighten a comprehensive understanding of population health, with methods and strategies implemented in this work recommended for future expansion to produce timely, actionable data in support of public health.
ContributorsBowes, Devin Ashley (Author) / Halden, Rolf U (Thesis advisor) / Krajmalnik-Brown, Rosa (Thesis advisor) / Conroy-Ben, Otakuye (Committee member) / Varsani, Arvind (Committee member) / Whisner, Corrie (Committee member) / Arizona State University (Publisher)
Created2022
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Description
Existing water quality sensors in surface, environmental, and drinking water systems are not well suited for long-term, scalable use as they require calibration, replacement of reagents, and are subject to biofouling which degrades measurement accuracy. Microbial Potentiometric Sensors (MPSs) offer an alternative approach to water quality monitoring by monitoring a

Existing water quality sensors in surface, environmental, and drinking water systems are not well suited for long-term, scalable use as they require calibration, replacement of reagents, and are subject to biofouling which degrades measurement accuracy. Microbial Potentiometric Sensors (MPSs) offer an alternative approach to water quality monitoring by monitoring a biofilm-mediated potentiometric response to diverse water quality parameters. MPS biofilms grow naturally on graphite electrodes in diverse aqueous systems, are regenerative, and their potentiometric response correlates with numerous water quality parameters. As such, the overarching hypothesis of this dissertation is that MPS signal can be used to assess water quality trends and that its signal is driven by biofilm vitality. To test this hypothesis, machine learning, statistical regression, and the use of more complex, impedimetric measurement techniques were explored to characterize water quality trends in diverse water systems. This was accomplished by completing three dissertation objectives: 1.) Assess whether Machine Learning/Artificial Intelligence (ML/AI) tools can be used to disaggregate various surface water quality parameter values from Open Circuit Potential (OCP) signals produced by MPSs; 2.) Determine whether residual free chlorine concentration in drinking water could be determined by monitoring MPSs; and 3.) Determine whether OCP and/or Electrochemical Impedance Spectroscopy (EIS)-derived impedance data from an MPS can be used to determine water quality trends while confirming its biological origins. The findings confirm the hypothesis by demonstrating that ML/AI can be used to disaggregate MPS signal and determine numerous water quality parameters, offering unique opportunities for real-time monitoring of aqueous environments. Additionally, MPSs are particularly useful in measuring free chlorine concentrations in drinking water distribution systems which offers opportunities for scalable, in-situ, continuous monitoring of chlorine throughout a distribution network. Finally, the findings demonstrate that coupling MPSs’ OCP signal with more advanced measurement techniques such as EIS can improve understanding of drinking water quality trends, however current open source, affordable technologies capable of conducting EIS are prone to high measurement noise and are not currently accurate enough to be used in drinking water systems.
ContributorsSaboe, Daniel (Author) / Hristovski, Kiril (Thesis advisor) / Olson, Larry (Committee member) / Perreault, Francois (Committee member) / Arizona State University (Publisher)
Created2022
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Description
The CNC mill is a highly valuable tool for engineering design, allowing for the creation of precise and complex metal parts. However, due to their high cost, many engineers do not have access to these machines until they enter industry, limiting the knowledge and experience of engineering students. This also

The CNC mill is a highly valuable tool for engineering design, allowing for the creation of precise and complex metal parts. However, due to their high cost, many engineers do not have access to these machines until they enter industry, limiting the knowledge and experience of engineering students. This also restricts the level of engineering design they can participate in as they are limited to lower strength materials and processes. To expand the possibilities for engineering students, hobbyists, and small businesses, we created a reliable and affordable desktop CNC mill. Our machine is capable of cutting non-ferrous metals such as aluminum with 70μm repeatable part precision and be compatible with coolant and vacuum systems.
ContributorsHodson, Kenneth (Author) / Altobelli, Seth (Co-author) / Jordan, Shawn (Thesis director) / Sweeney, Rhett (Committee member) / Barrett, The Honors College (Contributor) / Engineering Programs (Contributor)
Created2023-05
Description

Cornhole, traditionally seen as tailgate entertainment, has rapidly risen in popularity since the launching of the American Cornhole League in 2016. However, it lacks robust quality control over large tournaments, since many of the matches are scored and refereed by the players themselves. In the past, there have been issues

Cornhole, traditionally seen as tailgate entertainment, has rapidly risen in popularity since the launching of the American Cornhole League in 2016. However, it lacks robust quality control over large tournaments, since many of the matches are scored and refereed by the players themselves. In the past, there have been issues where entire competition brackets have had to be scrapped and replayed because scores were not handled correctly. The sport is in need of a supplementary scoring solution that can provide quality control and accuracy over large matches where there aren’t enough referees present to score games. Drawing from the ACL regulations as well as personal experience and testimony from ACL Pro players, a list of requirements was generated for a potential automatic scoring system. Then, a market analysis of existing scoring solutions was done, and it found that there are no solutions on the market that can automatically score a cornhole game. Using the problem requirements and previous attempts to solve the scoring problem, a list of concepts was generated and evaluated against each other to determine which scoring system design should be developed. After determining that the chosen concept was the best way to approach the problem, the problem requirements and cornhole rules were further refined into a set of physical assumptions and constraints about the game itself. This informed the choice, structure, and implementation of the algorithms that score the bags. The prototype concept was tested on their own, and areas of improvement were found. Lastly, based on the results of the tests and what was learned from the engineering process, a roadmap was set out for the future development of the automatic scoring system into a full, market-ready product.

ContributorsGillespie, Reagan (Author) / Sugar, Thomas (Thesis director) / Li, Baoxin (Committee member) / Barrett, The Honors College (Contributor) / Engineering Programs (Contributor) / Dean, W.P. Carey School of Business (Contributor)
Created2023-05
Description

Our project is to create a simplified, portable, modular electrocardiogram known as ECG/EKG. Most medical facilities, including hospitals, clinics, and skilled nursing facilities, still rely on traditional 12-lead EKG equipment consisting of a large cart with long 10 wires. These wires can be a pain to constantly detangle and rearrange

Our project is to create a simplified, portable, modular electrocardiogram known as ECG/EKG. Most medical facilities, including hospitals, clinics, and skilled nursing facilities, still rely on traditional 12-lead EKG equipment consisting of a large cart with long 10 wires. These wires can be a pain to constantly detangle and rearrange to determine a person’s heart conditions. This creates issues in fast paced scenarios such as when a patient is experiencing a heart attack and needs an EKG stat. Additionally, the current technology can be somewhat unreliable at determining heart conditions, causing providers to request multiple EKG’s for patients. With our improved versatile EKG, we can help solve these issues and implement additional outpatient use with its portable features. This can be done by remotely monitoring heart conditions during activities such as exercise, sleep, or stressful events, without worrying about wire disturbance.

ContributorsLam, Jadon (Author) / Mullins, Hunter (Co-author) / Huang, Hai (Co-author) / Taut, Sarah (Co-author) / Lee, Youngju (Co-author) / Goode, Zachary (Co-author) / Byrne, Jared (Thesis director) / Swader, Melissa (Committee member) / McElfish, Alex (Committee member) / Barrett, The Honors College (Contributor) / Department of Information Systems (Contributor) / Human Systems Engineering (Contributor)
Created2023-05
Description

Our project is to create a simplified, portable, modular electrocardiogram known as ECG/EKG. Most medical facilities, including hospitals, clinics, and skilled nursing facilities, still rely on traditional 12-lead EKG equipment consisting of a large cart with long 10 wires. These wires can be a pain to constantly detangle and rearrange

Our project is to create a simplified, portable, modular electrocardiogram known as ECG/EKG. Most medical facilities, including hospitals, clinics, and skilled nursing facilities, still rely on traditional 12-lead EKG equipment consisting of a large cart with long 10 wires. These wires can be a pain to constantly detangle and rearrange to determine a person’s heart conditions. This creates issues in fast paced scenarios such as when a patient is experiencing a heart attack and needs an EKG stat. Additionally, the current technology can be somewhat unreliable at determining heart conditions, causing providers to request multiple EKG’s for patients. With our improved versatile EKG, we can help solve these issues and implement additional outpatient use with its portable features. This can be done by remotely monitoring heart conditions during activities such as exercise, sleep, or stressful events, without worrying about wire disturbance.

ContributorsMullins, Hunter (Author) / Lam, Jadon (Co-author) / Goode, Zachary (Co-author) / Taut, Sarah (Co-author) / Lee, Youngju (Co-author) / Huang, Hai (Co-author) / Byrne, Jared (Thesis director) / Swader, Melissa (Committee member) / McElfish, Alex (Committee member) / Barrett, The Honors College (Contributor) / Engineering Programs (Contributor)
Created2023-05
Description

Our project is to create a simplified, portable, modular electrocardiogram known as ECG/EKG. Most medical facilities, including hospitals, clinics, and skilled nursing facilities, still rely on traditional 12-lead EKG equipment consisting of a large cart with long 10 wires. These wires can be a pain to constantly detangle and rearrange

Our project is to create a simplified, portable, modular electrocardiogram known as ECG/EKG. Most medical facilities, including hospitals, clinics, and skilled nursing facilities, still rely on traditional 12-lead EKG equipment consisting of a large cart with long 10 wires. These wires can be a pain to constantly detangle and rearrange to determine a person’s heart conditions. This creates issues in fast paced scenarios such as when a patient is experiencing a heart attack and needs an EKG stat. Additionally, the current technology can be somewhat unreliable at determining heart conditions, causing providers to request multiple EKG’s for patients. With our improved versatile EKG, we can help solve these issues and implement additional outpatient use with its portable features. This can be done by remotely monitoring heart conditions during activities such as exercise, sleep, or stressful events, without worrying about wire disturbance.

ContributorsLee, Youngju (Author) / Taut, Sarah (Co-author) / Goode, Zachary (Co-author) / Lam, Jadon (Co-author) / Huang, Hai (Co-author) / Mullins, Hunter (Co-author) / Byrne, Jared (Thesis director) / Swader, Melissa (Committee member) / McElfish, Alex (Committee member) / Barrett, The Honors College (Contributor) / Department of Management and Entrepreneurship (Contributor) / Dean, W.P. Carey School of Business (Contributor)
Created2023-05
Description

Our project is to create a simplified, portable, modular electrocardiogram known as ECG/EKG. Most medical facilities, including hospitals, clinics, and skilled nursing facilities, still rely on traditional 12-lead EKG equipment consisting of a large cart with long 10 wires. These wires can be a pain to constantly detangle and rearrange

Our project is to create a simplified, portable, modular electrocardiogram known as ECG/EKG. Most medical facilities, including hospitals, clinics, and skilled nursing facilities, still rely on traditional 12-lead EKG equipment consisting of a large cart with long 10 wires. These wires can be a pain to constantly detangle and rearrange to determine a person’s heart conditions. This creates issues in fast paced scenarios such as when a patient is experiencing a heart attack and needs an EKG stat. Additionally, the current technology can be somewhat unreliable at determining heart conditions, causing providers to request multiple EKG’s for patients. With our improved versatile EKG, we can help solve these issues and implement additional outpatient use with its portable features. This can be done by remotely monitoring heart conditions during activities such as exercise, sleep, or stressful events, without worrying about wire disturbance.

ContributorsGoode, Zachary (Author) / Huang, Hai (Co-author) / Lam, Jadon (Co-author) / Lee, Youngju (Co-author) / Taut, Sarah (Co-author) / Mullins, Hunter (Co-author) / Byrne, Jared (Thesis director) / Swader, Melissa (Committee member) / Barrett, The Honors College (Contributor) / Engineering Programs (Contributor) / School of Manufacturing Systems and Networks (Contributor)
Created2023-05
Description

Our project is to create a simplified, portable, modular electrocardiogram known as ECG/EKG. Most medical facilities, including hospitals, clinics, and skilled nursing facilities, still rely on traditional 12-lead EKG equipment consisting of a large cart with long 10 wires. These wires can be a pain to constantly detangle and rearrange

Our project is to create a simplified, portable, modular electrocardiogram known as ECG/EKG. Most medical facilities, including hospitals, clinics, and skilled nursing facilities, still rely on traditional 12-lead EKG equipment consisting of a large cart with long 10 wires. These wires can be a pain to constantly detangle and rearrange to determine a person’s heart conditions. This creates issues in fast paced scenarios such as when a patient is experiencing a heart attack and needs an EKG stat. Additionally, the current technology can be somewhat unreliable at determining heart conditions, causing providers to request multiple EKG’s for patients. With our improved versatile EKG, we can help solve these issues and implement additional outpatient use with its portable features. This can be done by remotely monitoring heart conditions during activities such as exercise, sleep, or stressful events, without worrying about wire disturbance.

ContributorsHuang, Hai (Author) / Mullins, Hunter (Co-author) / Lam, Jadon (Co-author) / Taut, Sarah (Co-author) / Goode, Zachary (Co-author) / Lee, Youngju (Co-author) / Byrne, Jared (Thesis director) / Swader, Melissa (Committee member) / McElfish, Alex (Committee member) / Barrett, The Honors College (Contributor) / Department of Information Systems (Contributor) / Department of Supply Chain Management (Contributor)
Created2023-05
Description

Innovative teaching methods must be studied and implemented to optimize student learning and prepare future generations for complex challenges. Dr. Keith Hjelmstad, a professor at Arizona State University, developed such an approach, “The Mechanics Project,” and has implemented it in foundational engineering mechanics courses. Although course instructors have used traditional

Innovative teaching methods must be studied and implemented to optimize student learning and prepare future generations for complex challenges. Dr. Keith Hjelmstad, a professor at Arizona State University, developed such an approach, “The Mechanics Project,” and has implemented it in foundational engineering mechanics courses. Although course instructors have used traditional “lecture and read” approaches for generations, the world is changing, requiring a modified policy. In this thesis, I research, discuss, and analyze the positive effects of The Mechanics Project for civil engineering students based on its fundamental principles.

ContributorsWoodward, Caleb (Author) / Hjelmstad, Keith (Thesis director) / Chatziefstratiou, Efthalia (Committee member) / Barrett, The Honors College (Contributor) / Civil, Environmental and Sustainable Eng Program (Contributor)
Created2023-05