Plan B is a progestin-only emergency contraceptive pill (ECP) that can be taken within seventy-two hours of unprotected sex in order to prevent an unwanted pregnancy. Plan B was created in response to the United States Food and Drug Administration's (US FDA) 1997 request for new drug applications (NDAs) for a dedicated ECP product, and was approved for sales in the US in 1999. Duramed, a subsidiary of Barr Pharmaceuticals, manufactures Plan B for The Women's Capital Corporation (WCC), which owns the patent for Plan B. This technology is important in part because it expands women's reproductive rights by giving them greater control over their fertility. The mechanism of action of Plan B also raises questions about the moral status of the zygote.

Enovid was the first hormonal birth control pill. G. D. Searle and Company began marketing Enovid as a contraceptive in 1960. The technology was created by the joint efforts of many individuals and organizations, including Margaret Sanger, Katharine McCormick, Gregory Pincus, John Rock, Syntex, S.A. Laboratories, and G.D. Searle and Company Laboratories. Although there were many pieces and contributors to the final product, it was first conceived of and created by Gregory Pincus and Margaret Sanger through the Worcester Foundation in Worcester, Massachusetts, and was distributed by Searle, located in Chicago. This technology is important to the history of embryology because it changed the way people viewed birth control and revolutionized women's birth control methods. There is an extensive literature on the cultural and societal effects of the pill; for example, the effect it had on women's health care and how it changed perceptions of female sexuality.

The birth control pill, more commonly known as "the pill" is a form of contraception taken daily in pill form and consisting of synthetic hormones formulated to prevent ovulation, fertilization, and implantation of a fertilized egg. The US Food and Drug Administration (FDA) approved the first birth control pill, Enovid, in June 1960. It was the first contraceptive pill marketed worldwide. Since then a number of different pills have been developed, which differ in hormone type and dosage, and whether they contain one hormone (the minipill) or two (the combination pill). The development of an effective oral contraceptive was an enormous step in the reproductive rights movement, as contraceptives provided women and couples a means of planning families and limiting the number of children they had.

On 16 October 1916, Margaret Sanger opened one of the first birth control clinics in the United States in Brooklyn, New York, which some have called the Brownsville Clinic. Located at 46 Amboy Street, the clinic was a place where Sanger and her staff verbally communicated with women seeking information about birth control. During the early 1900s, both birth control and abortion were illegal in the US, and publication or circulation of information on both topics was deemed obscene and illegal by the federal Comstock Act. However, women still sought means to control unwanted pregnancies and visited the clinic to learn about birth control. The clinic was open for only ten days. It shut down after being found guilty of violation of the Comstock Act. The Brownsville Clinic represented a step toward the eventual founding of Planned Parenthood Federation of America, which Sanger led. Despite being short-lived, America’s first birth control clinic provided educational resources to women in New York and raised awareness of the birth control movement in the US through media exposure.