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Optimal experimental design for generalized linear models is often done using a pseudo-Bayesian approach that integrates the design criterion across a prior distribution on the parameter values. This approach ignores the lack of utility of certain models contained in the prior, and a case is demonstrated where the heavy

Optimal experimental design for generalized linear models is often done using a pseudo-Bayesian approach that integrates the design criterion across a prior distribution on the parameter values. This approach ignores the lack of utility of certain models contained in the prior, and a case is demonstrated where the heavy focus on such hopeless models results in a design with poor performance and with wild swings in coverage probabilities for Wald-type confidence intervals. Design construction using a utility-based approach is shown to result in much more stable coverage probabilities in the area of greatest concern.

The pseudo-Bayesian approach can be applied to the problem of optimal design construction under dependent observations. Often, correlation between observations exists due to restrictions on randomization. Several techniques for optimal design construction are proposed in the case of the conditional response distribution being a natural exponential family member but with a normally distributed block effect . The reviewed pseudo-Bayesian approach is compared to an approach based on substituting the marginal likelihood with the joint likelihood and an approach based on projections of the score function (often called quasi-likelihood). These approaches are compared for several models with normal, Poisson, and binomial conditional response distributions via the true determinant of the expected Fisher information matrix where the dispersion of the random blocks is considered a nuisance parameter. A case study using the developed methods is performed.

The joint and quasi-likelihood methods are then extended to address the case when the magnitude of random block dispersion is of concern. Again, a simulation study over several models is performed, followed by a case study when the conditional response distribution is a Poisson distribution.
ContributorsHassler, Edgar (Author) / Montgomery, Douglas C. (Thesis advisor) / Silvestrini, Rachel T. (Thesis advisor) / Borror, Connie M. (Committee member) / Pan, Rong (Committee member) / Arizona State University (Publisher)
Created2015
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Description
Bayesian networks are powerful tools in system reliability assessment due to their flexibility in modeling the reliability structure of complex systems. This dissertation develops Bayesian network models for system reliability analysis through the use of Bayesian inference techniques.

Bayesian networks generalize fault trees by allowing components and subsystems to be related

Bayesian networks are powerful tools in system reliability assessment due to their flexibility in modeling the reliability structure of complex systems. This dissertation develops Bayesian network models for system reliability analysis through the use of Bayesian inference techniques.

Bayesian networks generalize fault trees by allowing components and subsystems to be related by conditional probabilities instead of deterministic relationships; thus, they provide analytical advantages to the situation when the failure structure is not well understood, especially during the product design stage. In order to tackle this problem, one needs to utilize auxiliary information such as the reliability information from similar products and domain expertise. For this purpose, a Bayesian network approach is proposed to incorporate data from functional analysis and parent products. The functions with low reliability and their impact on other functions in the network are identified, so that design changes can be suggested for system reliability improvement.

A complex system does not necessarily have all components being monitored at the same time, causing another challenge in the reliability assessment problem. Sometimes there are a limited number of sensors deployed in the system to monitor the states of some components or subsystems, but not all of them. Data simultaneously collected from multiple sensors on the same system are analyzed using a Bayesian network approach, and the conditional probabilities of the network are estimated by combining failure information and expert opinions at both system and component levels. Several data scenarios with discrete, continuous and hybrid data (both discrete and continuous data) are analyzed. Posterior distributions of the reliability parameters of the system and components are assessed using simultaneous data.

Finally, a Bayesian framework is proposed to incorporate different sources of prior information and reconcile these different sources, including expert opinions and component information, in order to form a prior distribution for the system. Incorporating expert opinion in the form of pseudo-observations substantially simplifies statistical modeling, as opposed to the pooling techniques and supra Bayesian methods used for combining prior distributions in the literature.

The methods proposed are demonstrated with several case studies.
ContributorsYontay, Petek (Author) / Pan, Rong (Thesis advisor) / Montgomery, Douglas C. (Committee member) / Shunk, Dan L. (Committee member) / Du, Xiaoping (Committee member) / Arizona State University (Publisher)
Created2016
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Description

In this paper, a literature review is presented on the application of Bayesian networks applied in system reliability analysis. It is shown that Bayesian networks have become a popular modeling framework for system reliability analysis due to the benefits that Bayesian networks have the capability and flexibility to model complex

In this paper, a literature review is presented on the application of Bayesian networks applied in system reliability analysis. It is shown that Bayesian networks have become a popular modeling framework for system reliability analysis due to the benefits that Bayesian networks have the capability and flexibility to model complex systems, update the probability according to evidences and give a straightforward and compact graphical representation. Research on approaches for Bayesian network learning and inference are summarized. Two groups of models with multistate nodes were developed for scenarios from constant to continuous time to apply and contrast Bayesian networks with classical fault tree method. The expanded model discretized the continuous variables and provided failure related probability distribution over time.

ContributorsZhou, Duan (Author) / Pan, Rong (Thesis advisor) / McCarville, Daniel R. (Committee member) / Zhang, Muhong (Committee member) / Arizona State University (Publisher)
Created2014
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Description
Research methods based on the frequentist philosophy use prior information in a priori power calculations and when determining the necessary sample size for the detection of an effect, but not in statistical analyses. Bayesian methods incorporate prior knowledge into the statistical analysis in the form of a prior distribution. When

Research methods based on the frequentist philosophy use prior information in a priori power calculations and when determining the necessary sample size for the detection of an effect, but not in statistical analyses. Bayesian methods incorporate prior knowledge into the statistical analysis in the form of a prior distribution. When prior information about a relationship is available, the estimates obtained could differ drastically depending on the choice of Bayesian or frequentist method. Study 1 in this project compared the performance of five methods for obtaining interval estimates of the mediated effect in terms of coverage, Type I error rate, empirical power, interval imbalance, and interval width at N = 20, 40, 60, 100 and 500. In Study 1, Bayesian methods with informative prior distributions performed almost identically to Bayesian methods with diffuse prior distributions, and had more power than normal theory confidence limits, lower Type I error rates than the percentile bootstrap, and coverage, interval width, and imbalance comparable to normal theory, percentile bootstrap, and the bias-corrected bootstrap confidence limits. Study 2 evaluated if a Bayesian method with true parameter values as prior information outperforms the other methods. The findings indicate that with true values of parameters as the prior information, Bayesian credibility intervals with informative prior distributions have more power, less imbalance, and narrower intervals than Bayesian credibility intervals with diffuse prior distributions, normal theory, percentile bootstrap, and bias-corrected bootstrap confidence limits. Study 3 examined how much power increases when increasing the precision of the prior distribution by a factor of ten for either the action or the conceptual path in mediation analysis. Power generally increases with increases in precision but there are many sample size and parameter value combinations where precision increases by a factor of 10 do not lead to substantial increases in power.
ContributorsMiocevic, Milica (Author) / Mackinnon, David P. (Thesis advisor) / Levy, Roy (Committee member) / West, Stephen G. (Committee member) / Enders, Craig (Committee member) / Arizona State University (Publisher)
Created2014
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Description
Statistical mediation analysis has been widely used in the social sciences in order to examine the indirect effects of an independent variable on a dependent variable. The statistical properties of the single mediator model with manifest and latent variables have been studied using simulation studies. However, the single mediator model

Statistical mediation analysis has been widely used in the social sciences in order to examine the indirect effects of an independent variable on a dependent variable. The statistical properties of the single mediator model with manifest and latent variables have been studied using simulation studies. However, the single mediator model with latent variables in the Bayesian framework with various accurate and inaccurate priors for structural and measurement model parameters has yet to be evaluated in a statistical simulation. This dissertation outlines the steps in the estimation of a single mediator model with latent variables as a Bayesian structural equation model (SEM). A Monte Carlo study is carried out in order to examine the statistical properties of point and interval summaries for the mediated effect in the Bayesian latent variable single mediator model with prior distributions with varying degrees of accuracy and informativeness. Bayesian methods with diffuse priors have equally good statistical properties as Maximum Likelihood (ML) and the distribution of the product. With accurate informative priors Bayesian methods can increase power up to 25% and decrease interval width up to 24%. With inaccurate informative priors the point summaries of the mediated effect are more biased than ML estimates, and the bias is higher if the inaccuracy occurs in priors for structural parameters than in priors for measurement model parameters. Findings from the Monte Carlo study are generalizable to Bayesian analyses with priors of the same distributional forms that have comparable amounts of (in)accuracy and informativeness to priors evaluated in the Monte Carlo study.
ContributorsMiočević, Milica (Author) / Mackinnon, David P. (Thesis advisor) / Levy, Roy (Thesis advisor) / Grimm, Kevin (Committee member) / West, Stephen G. (Committee member) / Arizona State University (Publisher)
Created2017