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Description
NIPAAm co-DEAEMA hydrogels are a potential solution for sustained, local delivery of ketorolac tromethamine. Current methods of postoperative pain management, such as local anesthetics, NSAIDs, and opioids, can be improved by minimizing side effects while still effectively treating severe and extreme pain. Though high doses of ketorolac can be toxic, sustained, local delivery via hydrogels offers a promising solution. Four ketorolac release studies were conducted using PNDJ hydrogels formulated by Sonoran Biosciences. The first two studies tested a range of JAAm concentration between 1.4 and 2.2 mole percent. Both had high initial release rates lasting less than 7 days and appeared to be unaffected by JAAm content. Tobramycin slowed down the release of ketorolac but was unable to sustain release for more than 6 days. Incorporating DEAEMA prolonged the release of ketorolac for up to 14 days with significant reductions in initial burst release rate. Low LCST of NIPAAM co-DEAEMA polymer is problematic for even drug distribution and future in vivo applications.
ContributorsHui, Nathan (Author) / Vernon, Brent (Thesis director) / Heffernan, John (Committee member) / School of International Letters and Cultures (Contributor) / Harrington Bioengineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
Within recent years, the drive for increased sustainability within large corporations has drastically increased. One critical measure within sustainability is the diversion rate, or the amount of waste diverted from landfills to recycling, repurposing, or reselling. There are a variety of different ways in which a company can improve their diversion rate, such as repurposing paper. A conventional method would be to simply have a recycling bin for collecting all paper, but the concern for large companies then becomes a security issue as confidential papers may not be safe in a traditional recycling bin. Salt River Project (SRP) has tackled this issue by hiring a third-party vendor (TPV) and having all paper placed into designated, secure shredding bins whose content is shredded upon collection and ultimately recycled into new material. However, while this effort is improving their diversion, the question has arisen of how to make the program viable in the long term based on the costs required to sustain it. To tackle this issue, this thesis will focus on creating a methodology and sampling plan to determine the appropriate level of a third-party recycling service required and to guide efficient bin-sizing solutions. This will in turn allow for SRP to understand how much paper waste is being produced and how accurately they are being charged for TPV services.
ContributorsHolladay, Amy E. (Author) / Escobedo, Adolfo (Thesis director) / Kucukozyigit, Ali (Committee member) / Industrial, Systems & Operations Engineering Prgm (Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
The goal of this thesis project was to build an understanding of supersonic projectile dynamics through the creation of a trajectory model that incorporates several different aerodynamic concepts and builds a criteria for the stability of a projectile. This was done iteratively where the model was built from a foundation of kinematics with various aerodynamic principles being added incrementally. The primary aerodynamic principle that influenced the trajectory of the projectile was in the coefficient of drag. The drag coefficient was split into three primary components: the form drag, skin friction drag, and base pressure drag. These together made up the core of the model, additional complexity served to increase the accuracy of the model and generalize to different projectile profiles.
ContributorsBlair, Martin (Co-author) / Armenta, Francisco (Co-author) / Takahashi, Timothy (Thesis director) / Herrmann, Marcus (Committee member) / Mechanical and Aerospace Engineering Program (Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
This project draws sustainability material out of the textbook and into the body using a
role play simulation modeled around Michigan wolf management. In this case, role play simulation is a game fabricated to reflect the complexity of real-world conflict. The goal of the exercise is to engage players in mock negotiation and expand their knowledge of wicked environmental problems. By encouraging participants to question their own thought process, the activity aims to foster a transformational experience.
role play simulation modeled around Michigan wolf management. In this case, role play simulation is a game fabricated to reflect the complexity of real-world conflict. The goal of the exercise is to engage players in mock negotiation and expand their knowledge of wicked environmental problems. By encouraging participants to question their own thought process, the activity aims to foster a transformational experience.
ContributorsVermeer, Danielle Nicole (Author) / Cloutier, Scott (Thesis director) / Movahed, Neda (Committee member) / School of Geographical Sciences and Urban Planning (Contributor) / School of Sustainability (Contributor) / School of International Letters and Cultures (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
Effective communication and engineering are not a natural pairing. The incongruence is because engineering students are focused on making, designing and analyzing. Since these are the core functions of the field there is not a direct focus on developing communication skills. This honors thesis explores the role and expectations for student engineers within the undergraduate engineering education experience to present and communicate ideas. The researchers interviewed faculty about their perspective on students' abilities with respect to their presentation skills to inform the design of a workshop series of interventions intended to make engineering students better communicators.
ContributorsAlbin, Joshua Alexander (Co-author) / Brancati, Sara (Co-author) / Lande, Micah (Thesis director) / Martin, Thomas (Committee member) / Industrial, Systems and Operations Engineering Program (Contributor) / Software Engineering (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
Solar panels need to be both cost effective and environmentally friendly to compete with traditional energy forms. Photovoltaic recycling has the potential to mitigate the harm of waste, which is often landfilled, while putting material back into the manufacturing process. Out of many, three methods show much promise: Full Recovery End-of-Life Photovoltaic (FRELP), mechanical, and sintering-based recycling. FRELP recycling has quickly gained prominence in Europe and promises to fully recover the components in a solar cell. The mechanical method has produced high yields of valuable materials using basic and inexpensive processes. The sintering method has the potential to tap into a large market for feldspar. Using a levelized cost of electricity (LCOE) analysis, the three methods could be compared on an economic basis. This showed that the mechanical method is least expensive, and the sintering method is the most expensive. Using this model, all recycling methods are less cost effective than the control analysis without recycling. Sensitivity analyses were then done on the effect of the discount rate, capacity factor, and lifespan on the LCOE. These results showed that the change in capacity factor had the most significant effect on the levelized cost of electricity. A final sensitivity analysis was done based on the decreased installation and balance of systems costs in 2025. With a 55% decrease in these costs, the LCOE decreased by close to $0.03/kWh for each method. Based on these results, the cost of each recycling method would be a more considerable proportion of the overall LCOE of the solar farm.
ContributorsMeister, William Frederick (Author) / Goodnick, Stephen (Thesis director) / Phelan, Patrick (Committee member) / Mechanical and Aerospace Engineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
Interview with J.D. Hill, co-founder of Recycled City
J.D. Hill is the co-founder of Recycled City LLC a business devoted to building a revolving relationship within the local food economy by limiting food waste. His business provides materials to create compost out of waste materials for residential customers and business. J.D.’s goals with his business are to inspire the community to participate in their local food economy, promote activism, focus on building farm land, and encourage a green economy in the Valley area. He is an ASU grad with degrees from the School of Sustainability and the W.P. Carey School of Business. This knowledge has shaped his view toward the ability of green businesses to flourish in the Phoenix area.
ContributorsHill, J.D. (Interviewee)
Created2015-08-07
Description
Interview with Mr. Arnott Duncan, owner of Duncan Family Farms, Inc.
Arnott Duncan is the owner of Duncan Family Farms. Farming runs in Arnott’s veins. He is a third generation farmer who has developed a deep connect to his local economy. However, interacting with Arizona food systems is not his only goal. Arnott also is actively engaged with educating the community about local produce. His farm provided U-Pick opportunities to the local community to provide people with in engaging experience toward food. The many years Arnott spent in the food industry has taught him that food, family, and community change the way we think but what we choose to do with that makes the difference in how we shape the world.
ContributorsDuncan, Arnott (Interviewee)
Created2015-08-07
Description
Freshwater is an essential component of life for most organisms on earth. "Civilization itself is built on a foundation of water (Fagan, 2011)," as people often congregate near water sources, and find innovative solutions to exploit these resources for food production and domestic needs. Rising demand for water due to altered lifestyles and population increase pose further stress on water availability. Alterations and pollution of freshwater ecosystems can dramatically compromise ecological services that many species, among them humans, depend on. Arid places are specifically vulnerable in regards to water, characterized by very low levels of precipitation, as well as many dry months, which are often followed by a short time of severe storms. Considering the interconnectedness of social and ecological systems in regards to freshwater services is crucial in order to sustainably manage freshwater resources and avoid ecological crises that in turn are likely to lead to social crises around the globe (Berkes et. al., 2003).
ContributorsHenenson, Einav (Author) / Anderies, M. John (Thesis director) / Aggarwal, Rimjhim (Committee member) / Golub, Aaron (Committee member) / Barrett, The Honors College (Contributor) / School of Sustainability (Contributor)
Created2012-12
Description
This project, Building the Backdrop, Expanding Perspectives on Sustainability, is a sculpture of a desert sunset that seeks to explore important sustainability issues and highlight the beauty in sustainable practices. Constructed for an honors thesis project at Arizona State University, the primary medium used was cardboard repurposed from package deliveries to bring attention to modern overconsumption of packaging materials and showcase our ability to give new life to traditionally single use materials. I invite you to interact with the piece by sharing photos of yourself in front of it to help spread its message and exploring the resources shared along with the sculpture.
ContributorsSandoval, Nicole (Author) / Hines, Taylor (Thesis director) / Meissinger, Ellen (Committee member) / Barrett, The Honors College (Contributor) / Department of Supply Chain Management (Contributor) / Dean, W.P. Carey School of Business (Contributor) / College of Integrative Sciences and Arts (Contributor)
Created2024-05