Description

The physiological phenomenon of sensing temperature is detected by transient

receptor (TRP) ion channels, which are pore forming proteins that reside in the

membrane bilayer. The cold and hot sensing TRP channels

The physiological phenomenon of sensing temperature is detected by transient

receptor (TRP) ion channels, which are pore forming proteins that reside in the

membrane bilayer. The cold and hot sensing TRP channels named TRPV1 and TRPM8

respectively, can be modulated by diverse stimuli and are finely tuned by proteins and

lipids. PIRT (phosphoinositide interacting regulator of TRP channels) is a small

membrane protein that modifies TRPV1 responses to heat and TRPM8 responses to cold.

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Date Created
  • 2018
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  • Text
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    • Doctoral Dissertation Biochemistry 2018

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