Many Fic domain proteins, through catalyzing post translational modifications (PTM) of protein substrates, functionally contribute to bacterial pathogenesis and the regulation of bacterial growth. Furthermore, one form of Fic-mediated regulation is the Fic toxin-antitoxin system, whereby an antitoxin interacts with and inhibits the Fic toxin. This study sought to determine the functional importance of Mycobacterium tuberculosis Fic and its putative antitoxin protein, Rv3642c. Using M.
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- Partial requirement for: M.S., Arizona State University, 2017Note typethesis
- Includes bibliographical references (pages 54-58)Note typebibliography
- Field of study: Molecular and cellular biology