Induced pluripotent stem cells (iPSCs) are an intriguing approach for neurological disease modeling, because neural lineage-specific cell types that retain the donors' complex genetics can be established in vitro. The statistical power of these iPSC-based models, however, is dependent on accurate diagnoses of the somatic cell donors; unfortunately, many neurodegenerative diseases are commonly misdiagnosed in live human subjects.
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- Partial requirement for: Ph.D., Arizona State University, 2013Note typethesis
- Includes bibliographical referencesNote typebibliography
- Field of study: Molecular and cellular biology