This project begins with an overview of the female reproductive tract microenvironment. It outlines the microenvironment of the vaginal, cervical, and endometrial epithelium and the interactions with immune cells and hormone cycles. The review also outlines the models currently used to study the female reproductive tract. The second chapter of the thesis is a study of the effects of pathogenic and commensal bacteria P. micra, F. magna, and F. nucleatum on cervical epithelial cells. This study analyzes cytotoxic effects after 24 hour infection of these bacteria.
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