Novel siloxane nanoprobes for molecular and cellular imagin Oxygen delivery is crucial for the development of healthy, functional tissue. Low tissue oxygenation, or hypoxia, is a characteristic that is common in many tumors. Hypoxia contributes to tumor malignancy and can reduce the success of chemotherapy and radiation treatment. There is a current need to noninvasively measure tumor oxygenation or pO2 in patients to determine a personalized treatment method. This project focuses on creating and characterizing nanoemulsions using a pO2 reporter molecule hexamethyldisiloxane (HMDSO) and its longer chain variants as well as assessing their cytotoxicity. We also explored creating multi-modal (MRI/Fluorescence) nanoemulsions.autGrucky, Marian LouisethsKodibagkar, VikramdgcRege, KaushaldgcStabenfeldt, SarahctbBarrett, The Honors CollegectbHarrington Bioengineering Programenghttps://hdl.handle.net/2286/R.I.1720935 pages115093930571628716197137469mgruckyIn Copyright2013-05TextBiomedical EngineeringHypoxiaImaging