Membrane proteins located within or as attachments to the cell membrane play critical roles in many essential cellular functions and host-pathogen interactions. Knowledge of the structure and function of membrane proteins in pathogenic species can allow for the development of specific vaccines and therapeutic agents against the pathogen. Francisella tularensis is an intracellular pathogen that is the causative agent of the severe, life-threatening infection, tularemia, in humans and other small mammals. F.
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