Matching Items (25)
Description
Though the likelihood is a useful tool for obtaining estimates of regression parameters, it is not readily available in the fit of hierarchical binary data models. The correlated observations negate the opportunity to have a joint likelihood when fitting hierarchical logistic regression models. Through conditional likelihood, inferences for the regression and covariance parameters as well as the intraclass correlation coefficients are usually obtained. In those cases, I have resorted to use of Laplace approximation and large sample theory approach for point and interval estimates such as Wald-type confidence intervals and profile likelihood confidence intervals. These methods rely on distributional assumptions and large sample theory. However, when dealing with small hierarchical datasets they often result in severe bias or non-convergence. I present a generalized quasi-likelihood approach and a generalized method of moments approach; both do not rely on any distributional assumptions but only moments of response. As an alternative to the typical large sample theory approach, I present bootstrapping hierarchical logistic regression models which provides more accurate interval estimates for small binary hierarchical data. These models substitute computations as an alternative to the traditional Wald-type and profile likelihood confidence intervals. I use a latent variable approach with a new split bootstrap method for estimating intraclass correlation coefficients when analyzing binary data obtained from a three-level hierarchical structure. It is especially useful with small sample size and easily expanded to multilevel. Comparisons are made to existing approaches through both theoretical justification and simulation studies. Further, I demonstrate my findings through an analysis of three numerical examples, one based on cancer in remission data, one related to the China’s antibiotic abuse study, and a third related to teacher effectiveness in schools from a state of southwest US.
ContributorsWang, Bei (Author) / Wilson, Jeffrey R (Thesis advisor) / Kamarianakis, Ioannis (Committee member) / Reiser, Mark R. (Committee member) / St Louis, Robert (Committee member) / Zheng, Yi (Committee member) / Arizona State University (Publisher)
Created2017
Description
Generalized Linear Models (GLMs) are widely used for modeling responses with non-normal error distributions. When the values of the covariates in such models are controllable, finding an optimal (or at least efficient) design could greatly facilitate the work of collecting and analyzing data. In fact, many theoretical results are obtained on a case-by-case basis, while in other situations, researchers also rely heavily on computational tools for design selection.
Three topics are investigated in this dissertation with each one focusing on one type of GLMs. Topic I considers GLMs with factorial effects and one continuous covariate. Factors can have interactions among each other and there is no restriction on the possible values of the continuous covariate. The locally D-optimal design structures for such models are identified and results for obtaining smaller optimal designs using orthogonal arrays (OAs) are presented. Topic II considers GLMs with multiple covariates under the assumptions that all but one covariate are bounded within specified intervals and interaction effects among those bounded covariates may also exist. An explicit formula for D-optimal designs is derived and OA-based smaller D-optimal designs for models with one or two two-factor interactions are also constructed. Topic III considers multiple-covariate logistic models. All covariates are nonnegative and there is no interaction among them. Two types of D-optimal design structures are identified and their global D-optimality is proved using the celebrated equivalence theorem.
Three topics are investigated in this dissertation with each one focusing on one type of GLMs. Topic I considers GLMs with factorial effects and one continuous covariate. Factors can have interactions among each other and there is no restriction on the possible values of the continuous covariate. The locally D-optimal design structures for such models are identified and results for obtaining smaller optimal designs using orthogonal arrays (OAs) are presented. Topic II considers GLMs with multiple covariates under the assumptions that all but one covariate are bounded within specified intervals and interaction effects among those bounded covariates may also exist. An explicit formula for D-optimal designs is derived and OA-based smaller D-optimal designs for models with one or two two-factor interactions are also constructed. Topic III considers multiple-covariate logistic models. All covariates are nonnegative and there is no interaction among them. Two types of D-optimal design structures are identified and their global D-optimality is proved using the celebrated equivalence theorem.
ContributorsWang, Zhongsheng (Author) / Stufken, John (Thesis advisor) / Kamarianakis, Ioannis (Committee member) / Kao, Ming-Hung (Committee member) / Reiser, Mark R. (Committee member) / Zheng, Yi (Committee member) / Arizona State University (Publisher)
Created2018
Description
The goal of diagnostic assessment is to discriminate between groups. In many cases, a binary decision is made conditional on a cut score from a continuous scale. Psychometric methods can improve assessment by modeling a latent variable using item response theory (IRT), and IRT scores can subsequently be used to determine a cut score using receiver operating characteristic (ROC) curves. Psychometric methods provide reliable and interpretable scores, but the prediction of the diagnosis is not the primary product of the measurement process. In contrast, machine learning methods, such as regularization or binary recursive partitioning, can build a model from the assessment items to predict the probability of diagnosis. Machine learning predicts the diagnosis directly, but does not provide an inferential framework to explain why item responses are related to the diagnosis. It remains unclear whether psychometric and machine learning methods have comparable accuracy or if one method is preferable in some situations. In this study, Monte Carlo simulation methods were used to compare psychometric and machine learning methods on diagnostic classification accuracy. Results suggest that classification accuracy of psychometric models depends on the diagnostic-test correlation and prevalence of diagnosis. Also, machine learning methods that reduce prediction error have inflated specificity and very low sensitivity compared to the data-generating model, especially when prevalence is low. Finally, machine learning methods that use ROC curves to determine probability thresholds have comparable classification accuracy to the psychometric models as sample size, number of items, and number of item categories increase. Therefore, results suggest that machine learning models could provide a viable alternative for classification in diagnostic assessments. Strengths and limitations for each of the methods are discussed, and future directions are considered.
ContributorsGonzález, Oscar (Author) / Mackinnon, David P (Thesis advisor) / Edwards, Michael C (Thesis advisor) / Grimm, Kevin J. (Committee member) / Zheng, Yi (Committee member) / Arizona State University (Publisher)
Created2018
Description
Guided by Tinto’s Theory of College Student Departure, I conducted a set of five studies to identify factors that influence students’ social integration in college science active learning classes. These studies were conducted in large-enrollment college science courses and some were specifically conducted in undergraduate active learning biology courses. Using qualitative and quantitative methodologies, I identified how students’ identities, such as their gender and LGBTQIA identity, and students’ perceptions of their own intelligence influence their experience in active learning science classes and consequently their social integration in college. I also determined factors of active learning classrooms and instructor behaviors that can affect whether students experience positive or negative social integration in the context of active learning. I found that students’ hidden identities, such as the LGBTQIA identity, are more relevant in active learning classes where students work together and that the increased relevance of one’s identity can have a positive and negative impact on their social integration. I also found that students’ identities can predict their academic self-concept, or their perception of their intelligence as it compares to others’ intelligence in biology, which in turn predicts their participation in small group-discussion. While many students express a fear of negative evaluation, or dread being evaluated negatively by others when speaking out in active learning classes, I identified that how instructors structure group work can cause students to feel more or less integrated into the college science classroom. Lastly, I identified tools that instructors can use, such as name tents and humor, which can positive affect students’ social integration into the college science classroom. In sum, I highlight inequities in students’ experiences in active learning science classrooms and the mechanisms that underlie some of these inequities. I hope this work can be used to create more inclusive undergraduate active learning science courses.
ContributorsCooper, Katelyn M (Author) / Brownell, Sara E (Thesis advisor) / Stout, Valerie (Committee member) / Collins, James (Committee member) / Orchinik, Miles (Committee member) / Zheng, Yi (Committee member) / Arizona State University (Publisher)
Created2018
Description
In the last decade, the population of honey bees across the globe has declined sharply leaving scientists and bee keepers to wonder why? Amongst all nations, the United States has seen some of the greatest declines in the last 10 plus years. Without a definite explanation, Colony Collapse Disorder (CCD) was coined to explain the sudden and sharp decline of the honey bee colonies that beekeepers were experiencing. Colony collapses have been rising higher compared to expected averages over the years, and during the winter season losses are even more severe than what is normally acceptable. There are some possible explanations pointing towards meteorological variables, diseases, and even pesticide usage. Despite the cause of CCD being unknown, thousands of beekeepers have reported their losses, and even numbers of infected colonies and colonies under certain stressors in the most recent years. Using the data that was reported to The United States Department of Agriculture (USDA), as well as weather data collected by The National Centers for Environmental Information (NOAA) and the National Centers for Environmental Information (NCEI), regression analysis was used to investigate honey bee colonies to find relationships between stressors in honey bee colonies and meteorological variables, and colony collapses during the winter months. The regression analysis focused on the winter season, or quarter 4 of the year, which includes the months of October, November, and December. In the model, the response variables was the percentage of colonies lost in quarter 4. Through the model, it was concluded that certain weather thresholds and the percentage increase of colonies under certain stressors were related to colony loss.
ContributorsVasquez, Henry Antony (Author) / Zheng, Yi (Thesis director) / Saffell, Erinanne (Committee member) / School of Mathematical and Statistical Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
Problems related to alcohol consumption cause not only extra economic expenses, but are an expense to the health of both drinkers and non-drinkers due to the harm directly and indirectly caused by alcohol consumption. Investigating predictors and reasons for alcohol-related problems is of importance, as alcohol-related problems could be prevented by quitting or limiting consumption of alcohol. We were interested in predicting alcohol-related problems using multiple linear regression and regression trees, and then comparing the regressions to the tree. Impaired control, anxiety sensitivity, mother permissiveness, father permissiveness, gender, and age were included as predictors. The data used was comprised of participants (n=835) sampled from students at Arizona State University. A multiple linear regression without interactions, multiple linear regression with two-way interactions and squares, and a regression tree were used and compared. The regression and the tree had similar results. Multiple interactions of variables predicted alcohol-related problems. Overall, the tree was easier to interpret than the regressions, however, the regressions provided specific predicted alcohol-related problems scores, whereas the tree formed large groups and had a predicted alcohol-related problems score for each group. Nevertheless, the tree still predicted alcohol-related problems nearly as well, if not better than the regressions.
ContributorsVoorhies, Kirsten Reed (Author) / McCulloch, Robert (Thesis director) / Zheng, Yi (Committee member) / Patock-Peckham, Julie (Committee member) / School of Mathematical and Statistical Sciences (Contributor) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12
Description
Statistical mediation analysis allows researchers to identify the most important the mediating constructs in the causal process studied. Information about the mediating processes can be used to make interventions more powerful by enhancing successful program components and by not implementing components that did not significantly change the outcome. Identifying mediators is especially relevant when the hypothesized mediating construct consists of multiple related facets. The general definition of the construct and its facets might relate differently to external criteria. However, current methods do not allow researchers to study the relationships between general and specific aspects of a construct to an external criterion simultaneously. This study proposes a bifactor measurement model for the mediating construct as a way to represent the general aspect and specific facets of a construct simultaneously. Monte Carlo simulation results are presented to help to determine under what conditions researchers can detect the mediated effect when one of the facets of the mediating construct is the true mediator, but the mediator is treated as unidimensional. Results indicate that parameter bias and detection of the mediated effect depends on the facet variance represented in the mediation model. This study contributes to the largely unexplored area of measurement issues in statistical mediation analysis.
ContributorsGonzález, Oscar (Author) / Mackinnon, David P (Thesis advisor) / Grimm, Kevin J. (Committee member) / Zheng, Yi (Committee member) / Arizona State University (Publisher)
Created2016
Description
The Pearson and likelihood ratio statistics are commonly used to test goodness-of-fit for models applied to data from a multinomial distribution. When data are from a table formed by cross-classification of a large number of variables, the common statistics may have low power and inaccurate Type I error level due to sparseness in the cells of the table. The GFfit statistic can be used to examine model fit in subtables. It is proposed to assess model fit by using a new version of GFfit statistic based on orthogonal components of Pearson chi-square as a diagnostic to examine the fit on two-way subtables. However, due to variables with a large number of categories and small sample size, even the GFfit statistic may have low power and inaccurate Type I error level due to sparseness in the two-way subtable. In this dissertation, the theoretical power and empirical power of the GFfit statistic are studied. A method based on subsets of orthogonal components for the GFfit statistic on the subtables is developed to improve the performance of the GFfit statistic. Simulation results for power and type I error rate for several different cases along with comparisons to other diagnostics are presented.
ContributorsZhu, Junfei (Author) / Reiser, Mark R. (Thesis advisor) / Stufken, John (Committee member) / Zheng, Yi (Committee member) / St Louis, Robert (Committee member) / Kao, Ming-Hung (Committee member) / Arizona State University (Publisher)
Created2017
Description
This article proposes a new information-based subdata selection (IBOSS) algorithm, Squared Scaled Distance Algorithm (SSDA). It is based on the invariance of the determinant of the information matrix under orthogonal transformations, especially rotations. Extensive simulation results show that the new IBOSS algorithm retains nice asymptotic properties of IBOSS and gives a larger determinant of the subdata information matrix. It has the same order of time complexity as the D-optimal IBOSS algorithm. However, it exploits the advantages of vectorized calculation avoiding for loops and is approximately 6 times as fast as the D-optimal IBOSS algorithm in R. The robustness of SSDA is studied from three aspects: nonorthogonality, including interaction terms and variable misspecification. A new accurate variable selection algorithm is proposed to help the implementation of IBOSS algorithms when a large number of variables are present with sparse important variables among them. Aggregating random subsample results, this variable selection algorithm is much more accurate than the LASSO method using full data. Since the time complexity is associated with the number of variables only, it is also very computationally efficient if the number of variables is fixed as n increases and not massively large. More importantly, using subsamples it solves the problem that full data cannot be stored in the memory when a data set is too large.
ContributorsZheng, Yi (Author) / Stufken, John (Thesis advisor) / Reiser, Mark R. (Committee member) / McCulloch, Robert (Committee member) / Arizona State University (Publisher)
Created2017
Description
Responsible test use requires validation \u2014 the process of collecting evidence to support the inferences drawn from test scores. In high-stakes testing contexts, the need for validation is especially great; the far-reaching nature of high-stakes testing affects the educational, professional, and financial futures of stakeholders. The Standards for Educational and Psychological Measurement (AERA et al., 2014) offers specific guidance in developing and implementing tests. Still, concerns exist over the extent to which test developers and users of high-stakes tests are making valid inferences from test scores. This paper explores the current state of high-stakes educational testing and the validity issues surrounding it. Drawing on measurement theory literature, educational literature, and professional standards of test development and use, I assess the significance of these concerns and their potential implications for the stakeholders of high-stakes testing programs.
ContributorsKasten, Justin Daniel (Author) / Zheng, Yi (Thesis director) / Pivovarova, Margarita (Committee member) / School of Mathematical and Statistical Sciences (Contributor) / Department of Economics (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05