Matching Items (1,533)
Filtering by

Clear all filters

Description

This year marks the 50th anniversary of the passing of Title IX, a piece of legislation which aims for dismantling gender discrimination. Even with such actions females, especially Black females are not proportionally represented in the world of sports. Due to this phenomenon, a study was funded by the Global

This year marks the 50th anniversary of the passing of Title IX, a piece of legislation which aims for dismantling gender discrimination. Even with such actions females, especially Black females are not proportionally represented in the world of sports. Due to this phenomenon, a study was funded by the Global Sport Institute to look at barriers for Black Women and Girls sport participation. Focus groups and interviews were used to gather data. They utilized a semi-structured approach using open-ended questions, and were recorded and later transcribed. After a secondary data analysis was performed on the focus group and interview transcripts it was found that community views and resources play an important role in the sports participation for Black girls and women. The topics of legislation history, schools, resources, finances, access, and media views were further researched in order to understand their impact on Black girls and women. A public service announcement (PSA) video was created in order to communicate these findings in a more accessible and modern way. The goal of the PSA video is to not only educate the public about this problem concerning Black girls and women but to also empower and encourage communities to fix it.

ContributorsGrambs, Amalia (Author) / Lopez, Bertha (Co-author) / Gottner, Adam (Co-author) / Brooks, Scott (Thesis director) / Flores, Stacey (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor)
Created2022-05
166258-Thumbnail Image.png
ContributorsGrambs, Amalia (Author) / Lopez, Bertha (Co-author) / Gottner, Adam (Co-author) / Brooks, Scott (Thesis director) / Flores, Stacey (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor)
Created2022-05
166259-Thumbnail Image.jpg
ContributorsGrambs, Amalia (Author) / Lopez, Bertha (Co-author) / Gottner, Adam (Co-author) / Brooks, Scott (Thesis director) / Flores, Stacey (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor)
Created2022-05
164935-Thumbnail Image.png
Description
By analyzing The Witcher and Game of Thrones fandoms, this research examines whether cosplayers adhere to social media or canon expectations of gender, sexuality, and violence. The study focuses on six canon female characters and how cosplayers emulate them on TikTok and Instagram. Along with a quantitative analysis, ten cosplayers

By analyzing The Witcher and Game of Thrones fandoms, this research examines whether cosplayers adhere to social media or canon expectations of gender, sexuality, and violence. The study focuses on six canon female characters and how cosplayers emulate them on TikTok and Instagram. Along with a quantitative analysis, ten cosplayers were interviewed regarding their experiences with the fandom, source material, and cosplaying. The prediction was that cosplayers might conform to the standards of social media and the expectations of the social material; however, the findings implicate that fantrepreneurs mostly exclude sexualization and violence in their content, which suggests that cosplay continues to be used for transformative purposes.
ContributorsSears, Madison (Author) / Ingram-Waters, Mary (Thesis director) / McGibbney, Michelle (Committee member) / Barrett, The Honors College (Contributor) / Department of Psychology (Contributor) / School of Life Sciences (Contributor)
Created2022-05
164956-Thumbnail Image.png
Description

Currently, there are a number of studies confirming the link between exposure to certain chemicals, notably pesticides (Costello et. al. 2009, Wang et. al 2014), heavy metals such as arsenic (Chen et. al. 2017), ambient air pollution (Chen et. al. 2016), and chemicals specific to certain industrial fields (Nielsen et.

Currently, there are a number of studies confirming the link between exposure to certain chemicals, notably pesticides (Costello et. al. 2009, Wang et. al 2014), heavy metals such as arsenic (Chen et. al. 2017), ambient air pollution (Chen et. al. 2016), and chemicals specific to certain industrial fields (Nielsen et. al. 2021). However, few papers have attempted to perform a widespread analysis of the factors associated with Parkinson’s disease to identify whether the risk of developing the disease is dependent on different factors regionally. The goal of my thesis project is to complete a meta-analysis of toxins- where exposure may occur in both residential and occupational settings- that are associated with Parkinson’s to determine such regional differences and to identify any gaps in current literature, which may direct the course of future research in the field. As seen in this paper, it appears that occupational exposure to toxins appears to have the greatest impact on the risk of developing Parkinson’s disease, particularly pesticides and industrial toxins. However, there are numerous gaps with regards to data collection, regions studied, and quantification of toxin concentrations. However, this data may be useful in identifying at-risk populations if more extensive incremental and biopsy data regarding these toxins is provided.

ContributorsAravindan, Anumitha (Author) / Halden, Rolf (Thesis director) / Driver, Erin (Committee member) / Newell, Melanie (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor)
Created2022-05
165122-Thumbnail Image.png
Description
The purpose of this report is to review the current literature concerning management of the COVID-19 pandemic in homeless populations, and to use it to analyze the specific interventions established in Maricopa County—such as those aimed at education, vaccination and testing, and maintaining continuity of care. In doing so, I

The purpose of this report is to review the current literature concerning management of the COVID-19 pandemic in homeless populations, and to use it to analyze the specific interventions established in Maricopa County—such as those aimed at education, vaccination and testing, and maintaining continuity of care. In doing so, I hope to illustrate the unique challenges faced by people experiencing homelessness, provide context for disparities in health outcome, and inform action for both the ongoing pandemic and future outbreaks
ContributorsNewell, James (Author) / Gaughan, Monica (Thesis director) / Hruschka, Daniel (Committee member) / Barrett, The Honors College (Contributor) / School of Human Evolution & Social Change (Contributor) / School of Life Sciences (Contributor) / Watts College of Public Service & Community Solut (Contributor)
Created2022-05
165129-Thumbnail Image.png
Description

Age is the most significant risk factor for cancer development in humans. The somatic mutation theory postulates that the accumulation of genomic mutations over time results in cellular function degradation which plays an important role in understanding aging and cancer development. Specifically, degradation of the mechanisms that underlie somatic maintenance

Age is the most significant risk factor for cancer development in humans. The somatic mutation theory postulates that the accumulation of genomic mutations over time results in cellular function degradation which plays an important role in understanding aging and cancer development. Specifically, degradation of the mechanisms that underlie somatic maintenance can occur due to decreased immune cell function and genomic responses to DNA damage. Research has shown that this degradation can lead to the accumulation of mutations that can cause cancer in humans. Despite recent advances in our understanding of cancer in non-human species, how this risk factor translates across species is poorly characterized. Here, we analyze a veterinarian cancer dataset of 4,178 animals to investigate if age related cancer prevalence is similar in non-human animals. We intend for this work to be used as a primary step towards understanding the potential overlap and/or uniqueness between human and non-human cancer risk factors. This study can be used to better understand cancer development and how evolutionary processes have shaped somatic maintenance across species.

ContributorsAksoy, Selin (Author) / Maley, Carlo (Thesis director) / Boddy, Amy (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor) / Department of Psychology (Contributor)
Created2022-05
165130-Thumbnail Image.png
Description

There is increasing interest in understanding how active learning affects students’ mental health as science courses transition from traditional lecture to active learning. Prior research has found that active learning can both alleviate and exacerbate undergraduate mental health problems. Existing studies have only examined the relationship between active learning and

There is increasing interest in understanding how active learning affects students’ mental health as science courses transition from traditional lecture to active learning. Prior research has found that active learning can both alleviate and exacerbate undergraduate mental health problems. Existing studies have only examined the relationship between active learning and anxiety. No studies have examined the relationship between active learning and undergraduate depression. To address this gap in the literature, we conducted hour-long exploratory interviews with 29 students with depression who had taken active learning science courses across six U.S. institutions. We probed what aspects of active learning practices exacerbate or alleviate depressive symptoms and how students’ depression affects their experiences in active learning. We found that aspects of active learning practices exacerbate and alleviate students’ depressive symptoms, and depression negatively impacts students’ experiences in active learning. The underlying aspects of active learning practices that impact students’ depression fall into four overarching categories: inherently social, inherently engaging, opportunities to compare selves to others, and opportunities to validate or invalidate intelligence. We hope that by better understanding the experiences of undergraduates with depression in active learning courses we can create more inclusive learning environments for these students.

ContributorsAraghi, Tala (Author) / Cooper, Katelyn (Thesis director) / Brownell, Sara (Committee member) / Busch, Carly (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor)
Created2022-05
165136-Thumbnail Image.png
Description
Breast cancer can be imaged at greater depths using photoacoustic imaging to differentiate between cancerous and non-cancerous tissue. Current photoacoustic modalities struggle to display images in real-time because of the required image reconstruction. In this work, we aim to create a real-time photoacoustic imaging system where the photoacoustic effect is

Breast cancer can be imaged at greater depths using photoacoustic imaging to differentiate between cancerous and non-cancerous tissue. Current photoacoustic modalities struggle to display images in real-time because of the required image reconstruction. In this work, we aim to create a real-time photoacoustic imaging system where the photoacoustic effect is detected through changes in index of refraction. To reach this aim, two methods are applied to visualize the acoustic waves including Schlieren optics and differential interference contrast microscopy. This combined approach provides a new tool for the widespread application in clinical settings.
ContributorsSmetanick, Derek (Author) / Burgett, Joshua (Co-author) / Smith, Barbara (Thesis director) / Muthuswamy, Jitendran (Committee member) / Barrett, The Honors College (Contributor) / Harrington Bioengineering Program (Contributor) / School of Life Sciences (Contributor)
Created2022-05
165142-Thumbnail Image.png
Description

The Mohawk (mkx) gene functions as a transcriptional repressor for tendon morphogenesis during embryonic development. Previous research showed that mkx KO mice overexpressed the osteogenic gene Runx2. Runx2 plays a role in recognition and long-term immune memory. A study showed Runx2 KO mice had a significantly lower number of CD8

The Mohawk (mkx) gene functions as a transcriptional repressor for tendon morphogenesis during embryonic development. Previous research showed that mkx KO mice overexpressed the osteogenic gene Runx2. Runx2 plays a role in recognition and long-term immune memory. A study showed Runx2 KO mice had a significantly lower number of CD8 T cells specific to lymphocytic choriomeningitis virus (LCMV) and CD8 memory precursor T cells. To determine the direct effects of Mohawk expression on the immune system, development, acute response, and immune memory of innate, B and T cells were compared between WT and mkx KO mice after LCMV infection. Paired t-test analyses were performed between KO and WT data. We first found significantly higher numbers of granulocytes and dendritic cells in the periphery but lower numbers of B cells in the bone marrow and T cells in the thymus of KO mice. When analyzing immune response, we observed a significantly high number of activated CD8 T cells that proliferated in the KO mice in response to the infection. Next, we found no difference in cytokine production for TNF and IFNγ which shows Mohawk does not impair acute immune response. Finally, we found no significant difference between WT and KO mice in the CD8 T cells' ability to make an immune memory. In the present study, we found that, fewer immune cells continued their maturation. However, Mohawk expression did not impact their acute response or ability to become memory cells once the T cells matured and became activated. Rather, T cells specific for LCMV were present in higher numbers in mkx KO mice. Further research will study the impact Mohawk has on both B and T cell memory.

ContributorsMethuku, Varshini (Author) / Blattman, Joseph (Thesis director) / Rawls, Alan (Committee member) / Appel, Nicole (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor)
Created2022-05