Matching Items (4)
ContributorsMarohnic, Chuck (Performer) / Champion, Chris (Performer) / Jones, Warren (Performer) / Moio, Dom (Performer) / Miller, Mark (Performer) / Endsley, Shane (Performer) / Jazz Repertory Band (Performer) / ASU Library. Music Library (Publisher)
Created2001-03-05
ContributorsPilafian, Sam (Director) / Lande, Art (Performer) / Endsley, Shane (Performer) / Williamson, Bruce (Performer) / Miller, Mark (Performer) / Young, Khabu Doug (Performer) / Killian, Dwight (Performer) / Concert Jazz Band (Performer) / Russian Dragon Band (Contributor) / ASU Library. Music Library (Publisher)
Created2001-03-06
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Description

Background: The historical Japanese influenza vaccination program targeted at schoolchildren provides a unique opportunity to evaluate the indirect benefits of vaccinating high-transmitter groups to mitigate disease burden among seniors. Here we characterize the indirect mortality benefits of vaccinating schoolchildren based on data from Japan and the US.

Methods: We compared age-specific influenza-related excess

Background: The historical Japanese influenza vaccination program targeted at schoolchildren provides a unique opportunity to evaluate the indirect benefits of vaccinating high-transmitter groups to mitigate disease burden among seniors. Here we characterize the indirect mortality benefits of vaccinating schoolchildren based on data from Japan and the US.

Methods: We compared age-specific influenza-related excess mortality rates in Japanese seniors aged ≥65 years during the schoolchildren vaccination program (1978–1994) and after the program was discontinued (1995–2006). Indirect vaccine benefits were adjusted for demographic changes, socioeconomics and dominant influenza subtype; US mortality data were used as a control.

Results: We estimate that the schoolchildren vaccination program conferred a 36% adjusted mortality reduction among Japanese seniors (95%CI: 17–51%), corresponding to ∼1,000 senior deaths averted by vaccination annually (95%CI: 400–1,800). In contrast, influenza-related mortality did not change among US seniors, despite increasing vaccine coverage in this population.

Conclusions: The Japanese schoolchildren vaccination program was associated with substantial indirect mortality benefits in seniors.

ContributorsCharu, Vivek (Author) / Viboud, Cecile (Author) / Simonsen, Lone (Author) / Sturm-Ramirez, Katharine (Author) / Shinjoh, Masayoshi (Author) / Chowell-Puente, Gerardo (Author) / Miller, Mark (Author) / Sugaya, Norio (Author) / College of Liberal Arts and Sciences (Contributor)
Created2011-11-07
ContributorsLande, Art (Performer) / Endsley, Shane (Performer) / Williamson, Bruce (Performer) / Miller, Mark (Performer) / Young, Khabu Doug (Performer) / Killian, Dwight (Performer) / Russian Dragon Band (Performer) / ASU Library. Music Library (Publisher)
Created2001-03-08