Matching Items (159)
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Influenza has shown its potential to affect and even kill millions of people within an extremely short time frame, yet studies and surveys show that the general public is not well educated about the facts about influenza, including prevention and treatment. For this reason, public perception of influenza is extremely

Influenza has shown its potential to affect and even kill millions of people within an extremely short time frame, yet studies and surveys show that the general public is not well educated about the facts about influenza, including prevention and treatment. For this reason, public perception of influenza is extremely skewed, with people generally not taking the disease as seriously as they should given its severity. To investigate the inconsistencies between action and awareness of best available knowledge regarding influenza, this study conducted literature review and a survey of university students about their knowledge, perceptions, and action taken in relationship to influenza. Due to their dense living quarters, constant daily interactions, and mindset that they are "immune" to fairly common diseases like influenza, university students are a representative sample of urban populations. According to the World Health Organization (WHO), 54% of the world's population lived in cities as of 2014 (Urban population growth). Between 2015 and 2020, the global urban population is expected to grow 1.84% per year, 1.63% between 2020 and 2025, and 1.44% between 2025 and 2030 (Urban population growth). Similar projections estimate that by 2017, an overwhelming majority of the world's population, even in less developed countries, will be living in cities (Urban population growth). Results of this study suggest possible reasons for the large gap between best available knowledge and the perceptions and actions of individuals on the other hand. This may lead to better-oriented influenza education initiatives, more effective prevention and treatment plans, and generally raise excitement and awareness surrounding public health and scientific communication.
ContributorsGur-Arie, Rachel Ellen Haviva (Author) / Maienschein, Jane (Thesis director) / Laubichler, Manfred (Committee member) / Creath, Richard (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor)
Created2014-12
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Influenza is a viral infection with the potential to infect millions worldwide. In the case of such a pandemic outbreak, direct patient interaction is handled by the medical community, composed of hospitals, medical professionals, and the policies that regulate them. The medical community is responsible not only for treating infected

Influenza is a viral infection with the potential to infect millions worldwide. In the case of such a pandemic outbreak, direct patient interaction is handled by the medical community, composed of hospitals, medical professionals, and the policies that regulate them. The medical community is responsible not only for treating infected individuals, but preventing the spread of influenza to healthy individuals. Given this responsibility, the medical community has drafted preparedness plans laying down guidelines for action in the case of an influenza pandemic. This project reviewed these preparedness plans for hospitals in Arizona as well as reviewing the literature produced by the Department of Health and Human Services to guide these plans. The review revealed that the medical community is woefully unprepared to handle the number of infected individuals, projected to be close to 90 million. Plans are disorganized, outdated, and nonexistent. The conclusions of this thesis offer suggestions for pandemic policy improvement.
ContributorsAbboud, Alexis J (Author) / Maienschein, Jane (Thesis director) / Creath, Richard (Committee member) / O'Neil, Erica (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor)
Created2014-05
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Emergency departments (EDs) across the country have been forced to accommodate an ever-expanding population of mental health patients. This study surveyed physicians and social workers in order to determine the most commonly treated mental illnesses in the ED, common frustrations in the care of mental health patients, limitations in the

Emergency departments (EDs) across the country have been forced to accommodate an ever-expanding population of mental health patients. This study surveyed physicians and social workers in order to determine the most commonly treated mental illnesses in the ED, common frustrations in the care of mental health patients, limitations in the provision of treatment, and possible changes and improvements to the treatment system for the future. Attitudes toward the deinstitutionalization movement of the 1960s also were assessed, as this movement is hypothesized to have contributed to the current strain on EDs with respect to treating mental health issues. In this thesis, the deinstirutionalization movement and possible implications for mental health treatment in EDs are reviewed' In addition, questionnaires were administered to a sample of 6 ED doctors and 2 ED social workers-. Survey responses suggest that more resources, including availability of ED staff psychiatrists and dedicated facilities for mental health patients' would offer improvements to the current system. With careful evaluation of the ability of the ED to meet the needs of mental health patients, alternative resources for more effective and successful treatment strategies may be developed that offer a compromise between institutionalization and the revolving door of the ED.
ContributorsWinikates, Kristina (Author) / Roberts, Nicole (Thesis director) / Maienschein, Jane (Committee member) / Tinsley, Barbara (Committee member) / Barrett, The Honors College (Contributor)
Created2012-05
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Waste generation in the U.S. has reached new heights, but the exploitation of Native American lands for waste disposal is nothing new. Many of the negative effects of massive waste production and toxic pollution, such as poor health outcomes and decreased property values, disproportionately burden impoverished, minority communities inside and

Waste generation in the U.S. has reached new heights, but the exploitation of Native American lands for waste disposal is nothing new. Many of the negative effects of massive waste production and toxic pollution, such as poor health outcomes and decreased property values, disproportionately burden impoverished, minority communities inside and outside the United States (Brulle and Pellow, 2006). Native American communities have long been exploited for their natural resources and land-use, but in recent decades Indian country has also become a common place to store nuclear, hazardous and municipal wastes. This project is a case study of a local Indian reservation, the Salt River Pima-Maricopa Indian Community, and examined the socio-historical context of the landfill operations in terms of five principles of environmental justice. Each principle was defined and key moments from the SRPMIC's landfill history were discussed to demonstrate ways that the situation has improved, stayed the same or worsened with regard to the rights outlined in each principle. It was concluded that there needs to be an acknowledgement by involved municipalities and industries of the historical context that make the SRPMIC and other nearby Native American communities "ideal" contractors for waste management. Additionally, while the SRPMIC could currently benefit from looking into the principles of environmental justice as a guide to manage past and operating landfills, the Community will have a specific opportunity to revisit these issues under closer scrutiny during the closure of the Salt River Landfill in 2032 in order to ensure more environmentally just outcomes. Finally, it was concluded that scholarship at the intersection of environmental justice and Native American communities should continue because looking closer at the ways that local Native American communities are facing and resisting environmental injustice can serve to develop future models for other communities facing similar challenges to achieving environmental justice.
ContributorsScott, Nicole Danielle (Author) / Kinzig, Ann (Thesis director) / Harlan, Sharon (Committee member) / Maienschein, Jane (Committee member) / Barrett, The Honors College (Contributor) / School of Community Resources and Development (Contributor) / School of Social Transformation (Contributor) / School of Human Evolution and Social Change (Contributor)
Created2015-05
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Studies in neocortical neurogenesis have experienced an explosive growth since the early 2000s, measured by the increasing number of publications each year. I examine here the influence of Arnold Kriegstein in the field using Topic Modeling, a set of algorithms that can be applied to a collection of texts to

Studies in neocortical neurogenesis have experienced an explosive growth since the early 2000s, measured by the increasing number of publications each year. I examine here the influence of Arnold Kriegstein in the field using Topic Modeling, a set of algorithms that can be applied to a collection of texts to elucidate the central themes of said collection. Using a Java-based software called MALLET, I obtained data for his corpus, and compared it to the texts of other researchers in the field. This latter collection, which I dub "General Corpus", was separated by year from 2000 to 2014. I found that Kriegstein's most frequently discussed topic concerned highly unique terms such as GABA, glutamate, and receptor, which did not appear in any of the primary topics of the General Corpus. This was in contrast to my initial hypothesis that Kriegstein's importance stemmed from his examination of different phenomena that constitute the broader aspect of neocortical neurogenesis. I predicted that the terms in Kriegstein's primary topic would appear many times throughout the topics of the General Corpus, but it was not so, aside from the common ones such as neurons, cortical, and development. Taken in tandem with NIH Reporter data, these results suggest that Kriegstein obtains a large amount of research funding because his studies concern unique topics when compared to others in the field. The implications of these findings are especially relevant in a world where funding is becoming increasingly difficult to come by.
ContributorsChhetri, Chandra Divyash (Author) / Laubichler, Manfred (Thesis director) / Maienschein, Jane (Committee member) / Aiello, Kenneth (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor)
Created2015-05
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Abortion is a highly controversial procedure, and it has divided the country into two factions: pro-life and pro-choice. This intense debate is marred by anger through protests and violent actions against supporters of abortion. With all of the tension surrounding the moral significance of the abortion issue, the question arises:

Abortion is a highly controversial procedure, and it has divided the country into two factions: pro-life and pro-choice. This intense debate is marred by anger through protests and violent actions against supporters of abortion. With all of the tension surrounding the moral significance of the abortion issue, the question arises: How did specific figureheads, events, and contributing factors lead to the generation of the stigma and polarization surrounding the dichotomy of pro-life versus pro-choice abortion stances in the United States of America?
ContributorsAbdi-Moradi, Sepehr (Author) / Maienschein, Jane (Thesis director) / O'Neil, Erica (Committee member) / Abboud, Alexis (Committee member) / Barrett, The Honors College (Contributor) / Department of Psychology (Contributor)
Created2015-05
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Prior to the legalization and regulation of abortion and contraception in the late twentieth century, women could not readily access safe birth control, abortion, and other reproductive health options at clinics and doctor's offices. Thus, women sought out alternative means to control their reproduction that were often illegal, unreliable, and

Prior to the legalization and regulation of abortion and contraception in the late twentieth century, women could not readily access safe birth control, abortion, and other reproductive health options at clinics and doctor's offices. Thus, women sought out alternative means to control their reproduction that were often illegal, unreliable, and unsafe, often because they were provided by untrained reproductive health care providers. The untrained providers who performed unregulated reproductive health services during the 1800s through the mid 1900s were often referred to as "female physicians," despite not having any formal medical background. Those providers filled a demand to serve women who were not able to tend to unwanted pregnancies and other reproductive issues on their own, but their role in the history of women's health has not been well understood. I have investigated the following questions: (1) How have women sought alternative non-medical approaches to managing reproduction, and (2) what historical patterns and situations can we see showing that non-medically trained people were active in the reproductive lives of women throughout the 19th and 20th centuries in the US? To study this, I have engaged in historical review methods to trace the evolution of reproductive health care providers and educators. Specifically, I have examined historically active people, organizations, and events that involved women seeking alternative care and how the state of women's health care effected women's medical outcome. Through my investigation, I found a large number and variety of non-medical providers and approaches to women's reproductive health solutions due to an unmet need for reproductive healthcare and restrictive laws. Women obtained concocted birth control pills, illegal abortions, home-brewed menopause relief treatments, and learned how to give self cervical examinations from non-medical providers. In response to the rigidity of the male dominated medical field, non-medical forces intervened and women's healthcare evolved beyond the traditional male physician's office into supportive healthcare groups like Planned Parenthood. My findings are relevant in the ongoing political debates surrounding issues like contraception and abortion access. By demonstrating the struggle for sound standard of care for non-medical reproductive health care providers during the nineteenth and early twentieth century, this project emphasizes what the standards of reproductive health care for abortion and contraception might be like if the organizations that made them so readily available, like Planned Parenthood, were defunded or criminalized in our modern setting.
ContributorsHorwitz, Rainey Frances (Author) / Maienschein, Jane (Thesis director) / Abboud, Alexis (Committee member) / Abboud, Carolina (Committee member) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
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Mr. Green has stage 4 prostate cancer which has spread to the bones and liver and has become resistant to radiation and standard chemotherapy treatment. After 3 rounds of chemotherapy, his primary oncologist recommends that he participate in a clinical trial. He went to Dr. Red at the Saguaro Clinic

Mr. Green has stage 4 prostate cancer which has spread to the bones and liver and has become resistant to radiation and standard chemotherapy treatment. After 3 rounds of chemotherapy, his primary oncologist recommends that he participate in a clinical trial. He went to Dr. Red at the Saguaro Clinic after reading on the internet about a new Phase 1 clinical trial that the clinic is hosting, which is designed to target a specific receptor called AB-111 that may be present in malignant prostate, cervical, ovarian, and breast cells. After signing consent and completing the blood screens in the morning at the clinic, Mr. Green is told his liver enzymes are too high and the ranges specified in the protocol prohibit him from enrolling. Mr. Green is noticeably affected and distressed at this news, and Dr. Red recommends end-of-life care. Behind the scenes, this event is noted on official medical documents and trial study rosters as a "screen fail." This narrative, while fictional, is realistic because similar events occur in cancer clinical trial sites on a regular basis. I look at the inner "world" and mental journey of possible clinical trial candidates as they seek out information about clinical trials and gain understanding of their function \u2014 specifically in the context of Phase 1 cancer clinical trials. To whom is the language of the term "screen failure" useful? How does excluding individuals from clinical trials protect their health and does the integrity of the trial data supersede the person's curative goals? What is the message that cancer patients (potential research subjects) receive regarding clinical trials from sources outside their oncologists?
ContributorsMcKane, Alexandra (Author) / Maienschein, Jane (Thesis director) / Ellison, Karin (Committee member) / Foy, Joseph (Committee member) / Barrett, The Honors College (Contributor)
Created2013-12
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The knowledge of medical genetics is currently used with prenatal testing, and the advancements in the field of behavioral genetics may someday allow for its use with prenatal testing as well. The use of prenatal procedures for medical phenotypes has its own implications and should these techniques be used for

The knowledge of medical genetics is currently used with prenatal testing, and the advancements in the field of behavioral genetics may someday allow for its use with prenatal testing as well. The use of prenatal procedures for medical phenotypes has its own implications and should these techniques be used for behavioral phenotypes, such implications can also apply. The complexity of behavior in terms of the factors that may affect it, along with the way it is conceptualized and perceived, adds further implications for prenatal testing of it. In this thesis, I discuss the qualitative, quantitative, and historical facets of prenatal testing for medical and behavioral phenotypes and the undercurrent of eugenics. I do so by presenting an example of the medical phenotype (cystic fibrosis) as a case for envisioning the implications of medical phenotypes before delving into examples of behavioral phenotypes (aggression, impulsivity, extraversion, and neuroticism) in order to explore the implications shared with those for medical phenotypes as well as those unique to it. These implications then set the foundation for a discussion of eugenics, and the considerations for how behavioral genetics with prenatal testing may give way to a modern form of it.
ContributorsMinai, Mandana (Author) / Maienschein, Jane (Thesis director) / Robert, Jason (Committee member) / Magnus, David (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor) / Department of Psychology (Contributor)
Created2014-05
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Civil litigation and medical malpractice both seem to be plagued by similar misperceptions. The general public, lawyers, physicians and our elected officials are all in considerable error regarding the reality behind civil litigation. The perception is that there are an increasing number of claims filed, and that in those cases

Civil litigation and medical malpractice both seem to be plagued by similar misperceptions. The general public, lawyers, physicians and our elected officials are all in considerable error regarding the reality behind civil litigation. The perception is that there are an increasing number of claims filed, and that in those cases that are filed the plaintiff is likely to win and be awarded a large sum of money. Regarding medical malpractice, in particular, is the belief that such litigation increases the over-all costs of healthcare by a significant dollar amount through the costs of litigation as well as the increasing instances of defensive medicine. Physicians further state that it is the absurd awards all too common in medical malpractice cases that are to blame for the out of control increases seen in medical malpractice premiums. These increases in premiums are said to have forced a large number of physicians out of practice that will hurt the general public's access to health care. These perceptions are at least reinforced by the media coverage that reports on the rare multimillion-dollar cases and from reports by insurance companies and physicians, in their attempt to lower their business costs by decreasing medical malpractice insurance premiums. By understanding the prevalence of such misperceptions, the truth behind the claims, and how such misinformation reaches the public and has spread to all levels of society, empirical data must be presented to the public in order to overcome the misperceptions.
ContributorsKohl, Mitchell Anthony (Author) / Robert, Jason (Thesis director) / Maienschein, Jane (Committee member) / Mossman, Kenneth (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor)
Created2013-05