Matching Items (159)
Description
Computational tools in the digital humanities often either work on the macro-scale, enabling researchers to analyze huge amounts of data, or on the micro-scale, supporting scholars in the interpretation and analysis of individual documents. The proposed research system that was developed in the context of this dissertation ("Quadriga System") works to bridge these two extremes by offering tools to support close reading and interpretation of texts, while at the same time providing a means for collaboration and data collection that could lead to analyses based on big datasets. In the field of history of science, researchers usually use unstructured data such as texts or images. To computationally analyze such data, it first has to be transformed into a machine-understandable format. The Quadriga System is based on the idea to represent texts as graphs of contextualized triples (or quadruples). Those graphs (or networks) can then be mathematically analyzed and visualized. This dissertation describes two projects that use the Quadriga System for the analysis and exploration of texts and the creation of social networks. Furthermore, a model for digital humanities education is proposed that brings together students from the humanities and computer science in order to develop user-oriented, innovative tools, methods, and infrastructures.
ContributorsDamerow, Julia (Author) / Laubichler, Manfred (Thesis advisor) / Maienschein, Jane (Thesis advisor) / Creath, Richard (Committee member) / Ellison, Karin (Committee member) / Hooper, Wallace (Committee member) / Renn, Jürgen (Committee member) / Arizona State University (Publisher)
Created2014
Description
Abortion is a controversial topic internationally. Most current debates about abortion concern when, if at all, it should be legal. However, researchers have shown many times that after an abortion ban, maternal and infant mortalities rise significantly, as women who seek out abortions do so regardless of abortion legality. So, is it possible to reduce abortions in a population without delegalizing abortion and, if so, how? Why do some countries have higher abortion rates than others in the presence of the same law?This dissertation answers both questions. First, I present historical evidence in the first comprehensive comparative analysis of all 15 post-Soviet countries, which have very similar abortion laws originating from the Union of Soviet Socialist Republics (USSR). Second, I use those findings to build the first agent-based model (ABM) of unintended pregnancies in a hypothetical artificial population.
USSR was the only country in the world to complete its demographic transition through abortion instead of modern contraception, and the Soviet government passed the first law in the world to allow abortion upon request in 1920. After the USSR dissolution in 1991, post-Soviet countries maintained very similar abortion laws, but had very different abortion rates for most years. Analysis of fertility data from post-Soviet countries shows that the prevalence of some specific contraceptive methods, namely the rhythm method (r = 0.82), oral pill (r = 0.56), and male condom (r = 0.51) are most strongly correlated with high abortion rates, and that sex education is a factor that reduces the rates in otherwise similar countries (p = 0.02).
The ABM shows that even basic sex education results in fewer abortions than no sex education or abstinence-based sex education (p < 0.01). In scenarios without sex education, basic quality of post-abortion contraceptive counseling (PACC) is better than no PACC or low-quality PACC at reducing abortions (p < 0.01). Still, the higher the quality of sex education or PACC, the fewer abortions in the artificial population. The ABM is adaptive and policy makers can use it as a decision-support tool to make evidence-based policy decisions regarding abortion, and, potentially, other sociobiological phenomena with some adjustments to the code.
ContributorsZiganshina Lienhard, Dina A. (Author) / Maienschein, Jane (Thesis advisor) / Gaughan, Monica (Thesis advisor) / Laubichler, Manfred (Committee member) / Ellison, Karin (Committee member) / Arizona State University (Publisher)
Created2023
Description
This dissertation investigates the convergence of the nation-state, biomedicine and (bio)capital around the construction of sickle cell disease as a subaltern disorder in the caste-based society of India. It inquires how sickle cell disease that developed evolutionarily due to environmental factors—and that is also globally racialized as a “Black disease”—has come to be associated with subaltern communities, particularly the indigenous, traditionally non-Hindu Adivasi communities of India. Such a subaltern association characterizes Adivasi biologies as inherently genetically “risky” thereby providing a biopolitical mandate to the Hindu-majoritarian Indian State to carry out biomedical interventions through promissory biocapital in the name of democratic inclusion. I center on the illness narratives of subaltern sickle cell sufferers to highlight how the caste-ization of sickle cell bodies in biomedical and policy discourses, and the attendant biocapital prospecting of subaltern biologies, are nonetheless challenged by communities through their lived experiences. Viewing this association from the Adivasi standpoint—marked by continuous dispossession and displacement—illuminates not only the biopolitical governance of subaltern reproduction by the Indian State. A primary objective of my dissertation project is also to use precarity as an epistemic site for interrogating the scopes and limits of a novel biopower formed by the nexus between the State, national biomedicine and transnational biocapital. This dissertation is therefore an attempt at unearthing the subjugated knowledges of Adivasi communities regarding alternative modes of existing in the world that continuously resist the assimilatory power of race, caste and capital. In ethnographically centering narratives of suffering among doubly (socially/economically) marginalized communities, the project illuminates the contradictions between public health measures that emphasize on sickle cell management through biomedical technologies of reproductive screening and the material conditions of sickle cell sufferers struggling to access basic medical care. This dissertation therefore juxtaposes policy interventions against community articulations of reproductive freedom that posits community health work as the fulcrum for developing reproductively just ecologies. At the same time, in utilizing multi-modal and multi-sited ethnographic methods, the project also contributes towards developing decolonial and digital ethnographic methods that are attentive to the aggravated precarity of marginalized communities in a pandemic prone world.
ContributorsDas, Sanghamitra (Author) / Smith, Lindsay A. (Thesis advisor) / Quan, H.L.T. (Committee member) / Maienschein, Jane (Committee member) / Prasad, Indulata (Committee member) / Robert, Jason (Committee member) / Arizona State University (Publisher)
Created2023
Description
Disabled people have historically lacked legal protection and often faced discrimination in healthcare, reproductive rights, education, and more despite being the largest minority group in the United States. One of the most common ways that American disability activists have advocated for their rights is by challenging discriminatory behavior or regulations in court and advocating for policy change in local, state, and federal governments. As a result, understanding the relationships between legislation and the judicial processes by which American judges approach disability discrimination is crucial to protecting and expanding the rights of disabled Americans. This study analyzes five American disability rights cases from the last fifty years as well as two foundational pieces of federal legislation, the Americans with Disabilities Act (ADA) and the Individuals with Disabilities Education Act (IDEA). I conducted this research as a member of the Embryo Project, where I wrote and peer-reviewed articles for the Embryo Project Encyclopedia, which is an online open-access resource for topics relating to reproduction, embryology, and development. In my articles, I summarize the litigation and holdings of each case with additional contextualization in science and society. The passage of the ADA represents a watershed moment after which the American judiciary observed the rights of the disabled as legislatively codified rather than only subject to interpretations of the Constitution. Since laws can be repealed far more easily than constitutional amendments, precedent from legislative interpretation is only as secure as the law on which it is based. Lawmakers must understand the need to craft legislation with reduced textual ambiguity to prevent undermining the original intent of the law. With the recent overturning of long-standing precedent and the composition of the Supreme Court as of 2023, disability rights are on fragile footing. Judicial behavior in response to disability legislation has historically narrowed the protections offered by federal statute and failed to bolster disability rights by refusing to base decisions on Constitutional protections.
ContributorsRoss, Nathaniel (Author) / Maienschein, Jane (Thesis advisor) / Yudell, Michael (Committee member) / Compton, Carolyn (Committee member) / Arizona State University (Publisher)
Created2023
Description
For my graduate thesis, I present an annotated bibliography that evaluates and summarizes a list of resources available for use in future research. The resources focus on
how pectus excavatum, a congenital birth anomaly affecting the thoracic wall, may
impact identity formation and subsequent behavior during a period characterized by
significant physical and psychological development, from the ages 12 to 18, known as
adolescence. I examine resources that specifically look at congenital birth anomalies,
pectus excavatum, developmental psychology, psychoanalysis, and identity crises. The
following provides background and an annotated bibliography to establish whether there
is a causal relationship between individuals born with congenital birth anomalies,
specifically pectus excavatum (PE), and the impact it has to identity development during
adolescence. This work is important to me because I was born with pectus excavatum,
and I believe a causal relationship does exist. While I claim the causal relationship does
exist, I should note this is conjecture and anecdotally based on 7 years of interacting with
patients in both a clinical and personal setting. The conversations are reflective of
discussions that have taken place about having been born with pectus excavatum and how
the condition has impacted our lives.
ContributorsMihuc, Michael (Author) / Maienschein, Jane (Thesis advisor) / Ellison, Karin (Committee member) / Gur-Arie, Rachel (Committee member) / Arizona State University (Publisher)
Created2023
Description
Writing speculative fiction is a valuable method for exploring the potential societal transformations elicited by advances in science and technology. The aim of this project is to use speculative fiction to explore the potential consequences of precision medicine for individuals’ daily lives. Precision medicine is a vision of the future in which medicine is about predicting, and ultimately preventing disease before symptoms arise. The idea is that identification of all the factors that influence health and contribute to disease development will translate to better and less expensive healthcare and empower individuals to take responsibility for maintaining their own health and wellness. That future, as envisioned by the leaders of the Human Genome Project, the Institute for Systems Biology, and the Obama administration’s Precision Medicine Initiative, is assumed to be a shared future, one that everyone desires and that is self-evidently “better” than the present. The aim of writing speculative fiction about a “precision medicine” future is to challenge that assumption, to make clear the values underpinning that vision of precision medicine, and to leave open the question of what other possible futures could be imagined instead.
ContributorsVenkatraman, Richa (Author) / Brian, Jennifer (Thesis advisor) / Maienschein, Jane (Thesis advisor) / Hurlbut, James (Committee member) / Arizona State University (Publisher)
Created2022
Description
Born in Ypsilanti, Michigan, on 2 February 1869, Charles Manning Child was the only surviving child of Mary Elizabeth and Charles Chauncey Child, a prosperous, old New England family. Growing up in Higganum, Connecticut, Child was interested in biology from an early age. He made extensive collections of plants and minerals on his family farm and went on to study biology at Wesleyan University, commuting from his family home. Child received his PhB in 1890 and MS in biology in 1892, and then went on to study in Leipzig after his parents death. He worked for a short time in the psychology laboratory of Wilhelm Wundt, and then pursued studies in zoology under the supervision of Rudolf Leuckhart. His doctoral dissertation investigated morphological aspects of insect sense organs. Leuckhart emphasized the functional purpose of morphological structures and led many of his students to develop and defend the notion of teleology, including Child, who completed his PhD in 1894.
ContributorsSunderland, Mary E. (Author) / Maienschein, Jane (Editor) / Arizona State University. School of Life Sciences. Center for Biology and Society. Embryo Project Encyclopedia. (Publisher) / Arizona Board of Regents (Publisher)
Created2007-10-23
Description
Conrad Hal Waddington's Organisers and Genes, published in 1940, is a summary of available research and theoretical framework for many concepts related to tissue differentiation in the developing embryo. The book is composed of two main conceptual sections. The first section explores the action and nature of the organizer, while the second section delves into genes and their influence on development.
ContributorsNavis, Adam R. (Author) / Maienschein, Jane (Editor) / Arizona State University. School of Life Sciences. Center for Biology and Society. Embryo Project Encyclopedia. (Publisher) / Arizona Board of Regents (Publisher)
Created2007-10-30
Description
Francesco Redi, son of Florentine physician Cecilia de' Ghinci and Gregorio Redi, was born in Arezzo, Italy, on 18 February 1626. He studied philosophy and medicine at the University of Pisa, graduating on 1 May 1647. A year later, Redi moved to Florence and registered at the Collegio Medico. There he served at the Medici Court as both the head physician and superintendent of the ducal pharmacy and foundry. Redi was also a member of the Accademia del Cimento, which flourished from 1657-1667. It was during this decade that Redi produced his most important works.
ContributorsBuettner, Kimberly A. (Author) / Maienschein, Jane (Editor) / Arizona State University. School of Life Sciences. Center for Biology and Society. Embryo Project Encyclopedia. (Publisher) / Arizona Board of Regents (Publisher)
Created2007-11-01
Description
Antoni van Leeuwenhoek was born in Delft, the Netherlands, on 24 October 1632 to Margriet Jacobsdochter van den Berch and Philips Thooniszoon, both of whom were middle-class artisans. He attended grammar school in Warmond, and then temporarily moved to Benthuizen to live with relatives. Eventually Leeuwenhoek left for Amsterdam to work as a cloth merchant's apprentice. Returning to Delft, he married Barbara de Mey on 29 July 1654, and worked as a shopkeeper. The marriage resulted in five children, only one of whom, Maria, outlived Leeuwenhoek.
ContributorsBolfert, Kristin (Author) / Maienschein, Jane (Editor) / Arizona State University. School of Life Sciences. Center for Biology and Society. Embryo Project Encyclopedia. (Publisher) / Arizona Board of Regents (Publisher)
Created2007-11-01