finding causes and treatments to revert misfolded proteins and ceasing progression due to
Diabetes Mellitus (DM). The goal of this review is to highlight the contribution of misfolded Tau
protein to AD through neurofibrillary tangles solely, and in conjunction with known causative
agents such as 𝛽-amyloid protein. Finally, it interprets the association of Tau with DM and its
effects on the progression of AD.
Yoga has become one of the most popular contemporary health approaches practiced by young adults in the United States. It is an ancient mind and body practice with origins in Indian philosophy dating to over 5,000 years ago. Yoga combines physical postures, rhythmic breathing, and meditative exercises to offer the participants a unique, holistic mind-body experience. In this report, the Sutras first introduced by Patanjali, an ancient Indian sage, are broken down into modern definitions. Each sutra has its own unique mental and physical benefits that can be attained by college students. Yama encourages maintaining a personal moral code. Niyama allows for personal connection and self-awareness. Asana refers to the poses that are still commonly practiced today. Pranayama helps to practice deep breathing. Pratyahara offers a disconnect from the world around us. Dharana allows us to focus and hone in on one thought. Dyana promotes a continuous flow of focus in meditation. Samadhi is reaching a state of pure relaxation. All of these take time and practice, but when implemented in different aspects of daily life, college students can reduce their overall stress and anxiety to improve focus and success.
Eosinophil peroxidase (EPX) is a marker of eosinophilic inflammation in allergic diseases. Currently, measuring EPX in nasal swabs as a surrogate for airway eosinophil levels is completed using a gold standard enzyme-linked immunosorbent assay (ELISA) lab test. The purpose of this project was to develop and validate a novel lateral flow assay (LFA) that measures EPX with the same sensitivity and range of detection as the gold standard EPX ELISA, but that can be efficiently used in clinical settings. The results of this project show that the EPX LFA is a promising method for measuring EPX in nasal swab samples. While future studies are needed for further validation, the EPX LFA could provide rapid point-of-care EPX measurements for clinicians and patients suffering with eosinophil-associated diseases.