Matching Items (70)
Description
The present study utilized longitudinal data from a high-risk community sample (n=254, 52.8% female, 47.2% children of alcoholics, 74% non-Hispanic Caucasian) to test questions concerning the effects of genetic risk, parental knowledge, and peer substance use on emerging adult substance use disorders (SUDs). Specifically, this study examined whether parental knowledge and peer substance use mediated the effects of parent alcohol use disorder (AUD) and genetic risk for behavioral undercontrol on SUD. The current study also examined whether genetic risk moderated effects of parental knowledge and peer substance use on risk for SUD. Finally, this study examined these questions over and above a genetic "control" which explained a large proportion of variance in the outcome, thereby providing a stricter test of environmental influences.
Analyses were performed in a path analysis framework. To test these research questions, the current study employed two polygenic risk scores. The first, a theory-based score, was formed using single-nucleotide polymorphisms (SNPs) from receptor systems implicated in the amplification of positive effects in the presence of new/exciting stimuli and/or pleasure derived from using substances. The second, an empirically-based score, was formed using a data-driven approach that explained a large amount of variance in SUDs. Together, these scores allowed the present study to test explanations for the relations among parent AUD, parental knowledge, peer substance use, and SUDs.
Results of the current study found that having parents with less knowledge or an AUD conferred greater risk for SUDs, but only for those at higher genetic risk for behavioral undercontrol. The current study replicated research findings suggesting that peer substance use mediated the effect of parental AUD on SUD. However, it adds to this literature by suggesting that some mechanism other than increased behavioral undercontrol explains relations among parental AUD, peer substance use, and emerging adult SUD. Taken together, these findings indicate that children of parents with AUDs comprise a particularly risky group, although likelihood of SUD within this group is not uniform. These findings also suggest that some of the most important environmental risk factors for SUDs exert effects that vary across level of genetic propensity.
Analyses were performed in a path analysis framework. To test these research questions, the current study employed two polygenic risk scores. The first, a theory-based score, was formed using single-nucleotide polymorphisms (SNPs) from receptor systems implicated in the amplification of positive effects in the presence of new/exciting stimuli and/or pleasure derived from using substances. The second, an empirically-based score, was formed using a data-driven approach that explained a large amount of variance in SUDs. Together, these scores allowed the present study to test explanations for the relations among parent AUD, parental knowledge, peer substance use, and SUDs.
Results of the current study found that having parents with less knowledge or an AUD conferred greater risk for SUDs, but only for those at higher genetic risk for behavioral undercontrol. The current study replicated research findings suggesting that peer substance use mediated the effect of parental AUD on SUD. However, it adds to this literature by suggesting that some mechanism other than increased behavioral undercontrol explains relations among parental AUD, peer substance use, and emerging adult SUD. Taken together, these findings indicate that children of parents with AUDs comprise a particularly risky group, although likelihood of SUD within this group is not uniform. These findings also suggest that some of the most important environmental risk factors for SUDs exert effects that vary across level of genetic propensity.
ContributorsBountress, Kaitlin (Author) / Chassin, Laurie (Thesis advisor) / Crnic, Keith (Committee member) / Lemery-Chalfant, Kathryn (Committee member) / MacKinnon, David (Committee member) / Arizona State University (Publisher)
Created2015
Description
The purpose of this study was to examine whether maternal personality (i.e., Agreeableness and Conscientiousness) predicted maternal positive parenting (i.e., warmth/sensitivity and structure), and whether maternal parenting predicted children's regulation and sympathy and/or prosocial behavior. Additionally, the mediated effect of maternal warmth/sensitivity on the relation between maternal Agreeableness and children's regulation and the mediated effect of maternal structure on the relation between maternal Agreeableness and children's observed sympathy/prosocial behavior were investigated. Maternal personality was measured when children (N = 256 at Time 1) were 18 months old; maternal parenting was assessed when children were 18, 30, and 42 months old; children's regulation and sympathy/prosocial behavior (observed and reported) were assessed when children were 30, 42, and 54 months old. Mothers reported on their personality; maternal warmth/sensitivity was observed; maternal structure was observed and mothers also reported on their use of reasoning; mothers and caregivers rated children's regulation (i.e., effortful control [EC]) and regulation was also observed; mothers and fathers rated children's prosocial behavior; sympathy and prosocial behavior were also observed. In a path analysis, Conscientiousness did not significantly predict maternal warmth/sensitivity or structure at 30 months, whereas Agreeableness marginally predicted maternal warmth/sensitivity at 30 months and significantly predicted maternal structure at 30 months. Maternal warmth/sensitivity at 18 months significantly predicted 30-month EC, and 30-month maternal warmth/sensitivity significantly predicted 42-month EC. Maternal structure at 30 months significantly predicted 42-month observed sympathy/prosocial behavior. Maternal warmth/sensitivity at 42 months significantly predicted 54-month observed sympathy/prosocial behavior and marginally predicted 54-month reported prosocial behavior. Maternal structure and EC did not significantly predict reported prosocial behavior across any time point. EC did not significantly predict observed sympathy/prosocial behavior across any time point and maternal warmth/sensitivity at 18 and 30 months did not predict observed or reported sympathy/prosocial behavior at 30 or 42 months, respectively. Maternal Agreeableness directly predicted 30-month reported prosocial behavior and additional paths suggested possible bidirectional relations between maternal warmth/sensitivity and structure. Mediation analyses were pursued for two indirect relations; however, neither mediated effect was significant. Additional results are presented, and findings (as well as lack thereof) are discussed in terms of extant literature.
ContributorsEdwards, Alison (Author) / Eisenberg, Nancy (Thesis advisor) / Spinrad, Tracy L. (Thesis advisor) / Lemery-Chalfant, Kathryn (Committee member) / Bradley, Robert A. (Committee member) / Arizona State University (Publisher)
Created2015
Description
Research on attachment in adults began by assuming parallels from attachment as a behavioral system for using relationships to balance the tradeoff between safety and exploration in infants, to the same tradeoff function in adults. Perhaps more pressing, for adults, are the novel social tradeoffs adults face when deciding how to invest resources between themselves and their close relationship partners. The current study investigated the role of the attachment system in navigating two such tradeoffs, in a sample of ASU undergraduates. In one tradeoff condition, participants had the option of working on puzzles to earn either themselves or their closest friend a monetary reward. In the second tradeoff condition, participants worked to earn monetary rewards for a close or new friend. Analyses showed no evidence of attachment avoidance predicting prioritizing redistributing money to a close friend in either condition. While there was no effect of anxiety on prioritizing one’s close friend over one’s self, there was a marginal effect in both prioritizing one’s close friend over a new friend when redistributing money and starting on the close friend’s word search first. Although attachment style largely did not predict earning or redistributing monetary rewards in these two relationship tradeoffs, implications for how these results fit within the broader theoretical perspective are discussed.
ContributorsYee, Claire (Author) / Shiota, Michelle N. (Thesis advisor) / Kenrick, Douglas T. (Committee member) / Lemery-Chalfant, Kathryn (Committee member) / Luecken, Linda J. (Committee member) / Arizona State University (Publisher)
Created2018
Description
This study examined whether early adversity at 30-months moderated the heritability of common and individual components of EF at 8 years. It was hypothesized that early adversity would not moderate the common EF factor, but instead moderate individual EF components. The sample included 208 twin pairs from the Arizona Twin Project. Early Adversity, assessed at 30 months of age, included Parenting Daily Hassles, low perceived MOS social support, punitive punishment (Parental Responses to Child Misbehavior), home chaos (Confusion, Hubbub, and Order Scale), CES-D maternal depression, and low maternal emotional availability. EF at 8 years included the Eriksen Flanker Task, Continuous Performance Task, Digit Span Forward and Backward, and parent-reported Attentional Focusing and Inhibitory Control (Temperament in Middle Childhood Questionnaire). For both early adversity and EF, the first principal components were extracted as composites. A confirmatory factor analysis was also conducted to index common EF. Genetic analyses were tested on the common EF composites as well as each individual task using umx. Univariate models revealed genetic influences on all individual measures and common EF, with broad sense heritability from .22 (Digit Span Backwards) to .61 (parent-reported inhibitory control). Shared environmental influences were found for the Flanker Task (.13) and parent-reported inhibitory control (.24), and E was moderate to high (.40-.73) for all measures except parent-report inhibitory control (.15) and attentional focusing (.31). Moderation of heritability was not observed in for Digit Span Forward, Digit Span Backward, and Attentional Focusing. However, the nonshared environment was moderated for Common EF, and the Flanker Task, and additive genes and the nonshared environment were moderated for the Continuous Performance Task and Inhibitory Control. Generally, total variance decreased as early adversity increased, suggesting that homes with low levels of adversity may allow children to interact with more proximal processes that can promote EF development.
ContributorsRea-Sandin, Gianna (Author) / Lemery-Chalfant, Kathryn (Thesis advisor) / Elam, Kit (Committee member) / Bradley, Robert (Committee member) / Arizona State University (Publisher)
Created2018
Description
The tendency for psychopathology to aggregate within families is well-documented, though little is known regarding the level of specificity at which familial transmission of symptomology occurs. The current study first tested competing higher-order structures of psychopathology in adolescence, indexing general and more specific latent factors. Second, parent-offspring transmission was tested for broadband domain specificity versus transmission of a general liability for psychopathology. Lastly, genetic and environmental mechanisms underlying the familial aggregation of psychopathology were examined using nuclear twin-family models. The sample was comprised of five hundred adolescent twin pairs (mean age 13.24 years) and their parents drawn from the Wisconsin Twin Project. Twins and parents completed independent diagnostic interviews. For aim 1, correlated factors, bifactor, and general-factor models were tested using adolescent symptom count data. For aim 2, structural equation modeling was used to determine whether broadband domain-specific transmission effects were necessary to capture parent-offspring resemblance in psychopathology above and beyond a general transmission effect indexed by the latent correlation between a parental internalizing factor and offspring P-factor. For aim 3, general factor models were fitted in both generations, and factor scores were subsequently extracted and used in nuclear twin-family model testing. Results indicated that the bifactor model exhibited the best fit to the adolescent data. Familial aggregation of psychopathology was sufficiently accounted for by the transmission of a general liability. Lastly, the best fitting reduced nuclear twin-family model indicated that additive genetic, sibling-specific shared environmental, and nonshared environmental influences contributed to general psychopathology. Parent-offspring transmission was accounted for by shared genetics only, whereas co-twin aggregation was additionally explained by sibling-specific shared environmental factors. Results provide novel insight into the specificity and etiology of the familial aggregation of psychopathology.
ContributorsOro, Veronica (Author) / Lemery-Chalfant, Kathryn (Thesis advisor) / Chassin, Laurie (Committee member) / Doane, Leah D (Committee member) / Arizona State University (Publisher)
Created2019
Description
The ability to self-regulate is arguably the single most important skill a child develops early in life. Self-regulation skills are consistently linked to indices of health, success, and wellbeing. The predominating perspective in self-regulation developmental research has emphasized the role of the early caregiving environment, specifically maternal characteristics and behavior, in shaping infants’ emerging regulatory skills. Using two complementary studies, this dissertation draws from a longitudinal sample of 322 low-income, Mexican American mother-infant dyads to better understand mothers’ and infants’ unique roles in contributing to emerging infant regulatory processes. The first study explores the unique contributions of intrinsic (i.e., infant gaze) and extrinsic (i.e., maternal gaze) factors in understanding infant dysregulated emotion and behavior during mother-infant interactions. Using actor partner interdependent models (APIMs), the role of infant and maternal gaze in understanding infant dysregulation were examined longitudinally across three mother-infant interaction tasks (i.e., soothing, teaching, and peekaboo), as well as within task. The expected relations among gaze and dysregulation did not emerge in the longitudinal model; however, differential patterns of associations emerged by task. Findings are discussed within the intersection of risk, culture, and the dyadic interaction context.
The second study connects patterns of specific maternal behaviors (i.e., acknowledging, gaze, vocal appropriateness, appropriate range of affect, consistency of style, resourcefulness, and touch) associated with maternal sensitivity to infant cortisol reactivity and recovery. Latent profile analysis (LPA) revealed four distinct combinations of maternal sensitivity behaviors. One pattern emerged as a risk profile—differentiated by higher maternal stress—and was associated with significantly more infant cortisol recovery compared to other profiles. Both studies offer a more nuanced understanding of the respective roles of infant and maternal factors in the development of self-regulation. Further explication of developmental processes involved in early regulatory functioning has implications for advancing both scientific knowledge and improved targeting of prevention and early intervention efforts to promote optimal child outcomes, particularly in populations that at increased risk for developmental psychopathology.
The second study connects patterns of specific maternal behaviors (i.e., acknowledging, gaze, vocal appropriateness, appropriate range of affect, consistency of style, resourcefulness, and touch) associated with maternal sensitivity to infant cortisol reactivity and recovery. Latent profile analysis (LPA) revealed four distinct combinations of maternal sensitivity behaviors. One pattern emerged as a risk profile—differentiated by higher maternal stress—and was associated with significantly more infant cortisol recovery compared to other profiles. Both studies offer a more nuanced understanding of the respective roles of infant and maternal factors in the development of self-regulation. Further explication of developmental processes involved in early regulatory functioning has implications for advancing both scientific knowledge and improved targeting of prevention and early intervention efforts to promote optimal child outcomes, particularly in populations that at increased risk for developmental psychopathology.
Contributorsvan Huisstede, Lauren (Author) / Crnic, Keith A (Thesis advisor) / Spinrad, Tracy (Committee member) / Bradley, Robert (Committee member) / Lemery-Chalfant, Kathryn (Committee member) / Arizona State University (Publisher)
Created2019
Description
Prior research has established associations between sleep duration and body mass index (BMI) scores and risk for obesity in middle childhood, but it is less clear whether other objectively- and subjectively-measured sleep indicators may be associated with BMI scores, weight status (e.g., obesity), and other estimates of weight and body fat such as waist circumference (WC) and percent body fat. Empirical studies have also demonstrated independent associations between broad self-regulation and sleep indicators and BMI scores, but no study to date has tested these factors in a model together and the extent to which associations between normative sleep problems, weight indicators, and effortful control (EC) may be explained by shared genetic or environmental influences. Data from a large longitudinal study of twins was used to test phenotypic associations between sleep problems at eight years and weight indicators at nine years, including whether EC at eight years moderates these associations. Additionally, multiple quantitative behavior genetic models were used to estimate unique and shared genetic and environmental covariances among normative sleep problems, weight indicators, and EC at eight years of age and whether additive genetic influence on weight in middle childhood differs by child weight status group. Phenotypic findings showed that greater sleep duration at eight years predicted greater decreases BMI at nine years of age for children with low levels of EC at eight years. Greater sleep midpoint variability at eight years predicted greater increases in percent body fat from eight to nine years of age for children with low EC at eight years. Behavior genetic findings showed greater environmental influences on parent-reported sleep duration and quality, as well as objective sleep midpoint variability. Similarly, associations between parent-reported sleep duration and sleep midpoint variability and other sleep indicators and EC were primarily accounted for by shared environmental factors. In contrast, there was high additive genetic influence on objective sleep quantity and quality, all weight indicators, and EC. Many of the associations between sleep indicators, sleep and weight indicators, and among weight indicators were entirely accounted for by shared additive genetic factors, suggesting that common, underlying sets of genes explain these relations.
ContributorsBreitenstein, Reagan Styles (Author) / Doane, Leah D. (Thesis advisor) / Lemery-Chalfant, Kathryn (Committee member) / Perez La Mar, Marisol (Committee member) / Grimm, Kevin (Committee member) / Arizona State University (Publisher)
Created2019
Description
Data from 749 Mexican-origin families across a seven-year span was used to test a model of the processes that moderate and mediate the transmission of religious values from parent to child. There were four separate reports of parenting practices (mother-report, father-report, adolescent’s report on mother, and adolescents report on father) and models were tested separately based on each report. Results suggest the mother’s role was more influential than fathers in transmitting religious values to their child, across parent and adolescent-report. In addition, results revealed different, and opposing effects for mother’s self-report of parenting practices and adolescents report on mother’s parenting behavior. Adolescents’ perceptions of maternal acceptance and consistency increased the likelihood of adolescents maintaining their religious values across adolescence, whereas mothers’ self-reported parenting practices negatively predicted late adolescents’ religious values. Lastly, results of this study lend support for the differential role of mothers in fathers in the development of adolescents’ social competence, specifically in the context of their religious values and use of positive parenting practices. The findings highlight the unique contributions of each reports’ perceptions in studying the transmission of religious values in families, as well, as the distinct role of mothers and fathers in the development of adolescents’ social competence.
ContributorsPerez, Vanesa Marie (Author) / Gonzales, Nancy A. (Thesis advisor) / Lemery-Chalfant, Kathryn (Committee member) / Grimm, Kevin J. (Committee member) / Arizona State University (Publisher)
Created2018
Description
The relationship between parent and child is one that has been studied intensively for years. Much of the previous research in this field has quantified the parent-child relationship through self-report measures, with a subsample coding behavior from videotape and averaging individual scores across the entire parent-child interaction. Using a dynamic systems approach, we attempted to gain a deeper understanding of the parent-child relationship by quantifying the relationship in terms of dyadic patterns using the software Gridware. We then used these dyadic patterns to predict internalizing and externalizing behaviors in eight-year-old twin children. Dyadic relationship patterns predicted externalizing behaviors such as aggression and conduct disorder (i.e., frequency and stability within negative attractor states, and infrequency and low stability in positive attractor states), but not internalizing behaviors. Findings provide a method for capturing variance in parent-child interactions that is important for children's externalizing behaviors. Future studies should utilize these patterns in understanding risk and resilience family processes for children's mental health and well being.
ContributorsEccles, Jenna Christine (Author) / Lemery-Chalfant, Kathryn (Thesis director) / Knight, George (Committee member) / Spinrad, Tracy (Committee member) / Barrett, The Honors College (Contributor) / T. Denny Sanford School of Social and Family Dynamics (Contributor) / Department of Psychology (Contributor)
Created2015-05
Description
We examined the relations between maternal depression, discipline practices, and toddler mental health outcomes, specifically competence and total problem behavior. Ethnicity was considered as a moderator in all analyses. For the first time, ethnicity was considered as a moderator of the heritability of toddler competence and total problem behavior. The data came from the Arizona Twin Project. A subsample containing only Caucasian (66%) and Hispanic (34%; 87% of Mexican descent) participants was used. Primary caregivers (>95% mothers) reported on levels of maternal depression, discipline practices, and their twins' competency and problem behaviors. It was hypothesized that maternal depression would be associated with less competency and more problem behaviors in toddlers; inductive discipline practices would be associated with higher competency and fewer problem behaviors; and punitive discipline practices would be associated with lower competency and more problem behaviors. Ethnicity was predicted to moderate only the relation between discipline practices and toddler mental health. Consistent with predictions, maternal depression predicted less competency and more problem behaviors, and inductive discipline predicted higher competency and fewer problem behaviors, while punitive discipline predicted lower competency and more problem behaviors. Ethnicity moderated the relation between maternal depression at 12 months and total problem behaviors. The heritability of competence and total problem behavior varied across the Caucasian and Hispanic samples.
ContributorsChon, Sarah Maria (Author) / Lemery-Chalfant, Kathryn (Thesis director) / Knight, George (Committee member) / Bradley, Robert (Committee member) / Barrett, The Honors College (Contributor) / Department of Psychology (Contributor) / School of International Letters and Cultures (Contributor)
Created2015-05