Matching Items (84)
ContributorsFisher, Caleb (Author) / Lee, Hyunglae (Thesis director) / Olivas, Alyssa (Committee member) / Barrett, The Honors College (Contributor) / Harrington Bioengineering Program (Contributor)
Created2023-05
ContributorsFisher, Caleb (Author) / Lee, Hyunglae (Thesis director) / Olivas, Alyssa (Committee member) / Barrett, The Honors College (Contributor) / Harrington Bioengineering Program (Contributor)
Created2023-05
ContributorsFisher, Caleb (Author) / Lee, Hyunglae (Thesis director) / Olivas, Alyssa (Committee member) / Barrett, The Honors College (Contributor) / Harrington Bioengineering Program (Contributor)
Created2023-05
ContributorsFisher, Caleb (Author) / Lee, Hyunglae (Thesis director) / Olivas, Alyssa (Committee member) / Barrett, The Honors College (Contributor) / Harrington Bioengineering Program (Contributor)
Created2023-05
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Description
Low back pain (LBP) is the most common symptom leading to hospitalization and medical assistance. In the US, LBP is the fifth most prevalent case for visiting hospitals. Approximately 2.06 million LBP incidents were reported during the timeline between 2004 and 2008. Globally, LBP occurrence increased by almost 200 million

Low back pain (LBP) is the most common symptom leading to hospitalization and medical assistance. In the US, LBP is the fifth most prevalent case for visiting hospitals. Approximately 2.06 million LBP incidents were reported during the timeline between 2004 and 2008. Globally, LBP occurrence increased by almost 200 million from 1990 to 2017. This problem is further implicated by physical and financial constraints that impact the individual’s quality of life. The medical cost exceeded $87.6 billion, and the lifetime prevalence was 84%. This indicates that the majority of people in the US will experience this symptom. Also, LBP limits Activities of Daily Living (ADL) and possibly affects the gait and postural stability. Prior studies indicated that LBP patients have slower gait speed and postural instability. To alleviate this symptom, the epidural injection is prescribed to treat pain and improve mobility function. To evaluate the effectiveness of LBP epidural injection intervention, gait and posture stability was investigated before and after the injection. While these factors are the fundamental indicator of LBP improvement, ADL is an element that needs to be significantly considered. The physical activity level depicts a person’s dynamic movement during the day, it is essential to gather activity level that supports monitoring chronic conditions, such as LBP, osteoporosis, and falls. The objective of this study was to assess the effects of Epidural Steroid Injection (ESI) on LBP and related gait and postural stability in the pre and post-intervention status. As such, the second objective was to assess the influence of ESI on LBP, and how it influences the participant’s ADL physical activity level. The results indicated that post-ESI intervention has significantly improved LBP patient’s gait and posture stability, however, there was insufficient evidence to determine the significant disparity in the physical activity levels. In conclusion, ESI depicts significant positive effects on LBP patients’ gait and postural parameters, however, more verification is required to indicate a significant effect on ADL physical activity levels.
ContributorsMoon, Seong Hyun (Author) / Lockhart, Thurmon (Thesis advisor) / Honeycutt, Claire (Committee member) / Peterson, Daniel (Committee member) / Lee, Hyunglae (Committee member) / Soangra, Rahul (Committee member) / Arizona State University (Publisher)
Created2023
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Description
This dissertation introduces and examines Soft Curved Reconfigurable Anisotropic Mechanisms (SCRAMs) as a solution to address actuation, manufacturing, and modeling challenges in the field of soft robotics, with the aim of facilitating the broader implementation of soft robots in various industries. SCRAM systems utilize the curved geometry of thin elastic

This dissertation introduces and examines Soft Curved Reconfigurable Anisotropic Mechanisms (SCRAMs) as a solution to address actuation, manufacturing, and modeling challenges in the field of soft robotics, with the aim of facilitating the broader implementation of soft robots in various industries. SCRAM systems utilize the curved geometry of thin elastic structures to tackle these challenges in soft robots. SCRAM devices can modify their dynamic behavior by incorporating reconfigurable anisotropic stiffness, thereby enabling tailored locomotion patterns for specific tasks. This approach simplifies the actuation of robots, resulting in lighter, more flexible, cost-effective, and safer soft robotic systems. This dissertation demonstrates the potential of SCRAM devices through several case studies. These studies investigate virtual joints and shape change propagation in tubes, as well as anisotropic dynamic behavior in vibrational soft twisted beams, effectively demonstrating interesting locomotion patterns that are achievable using simple actuation mechanisms. The dissertation also addresses modeling and simulation challenges by introducing a reduced-order modeling approach. This approach enables fast and accurate simulations of soft robots and is compatible with existing rigid body simulators. Additionally, this dissertation investigates the prototyping processes of SCRAM devices and offers a comprehensive framework for the development of these devices. Overall, this dissertation demonstrates the potential of SCRAM devices to overcome actuation, modeling, and manufacturing challenges in soft robotics. The innovative concepts and approaches presented have implications for various industries that require cost-effective, adaptable, and safe robotic systems. SCRAM devices pave the way for the widespread application of soft robots in diverse domains.
ContributorsJiang, Yuhao (Author) / Aukes, Daniel (Thesis advisor) / Berman, Spring (Committee member) / Lee, Hyunglae (Committee member) / Marvi, Hamidreza (Committee member) / Srivastava, Siddharth (Committee member) / Arizona State University (Publisher)
Created2023
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Description
Ferrofluidic microrobots have emerged as promising tools for minimally invasive medical procedures, leveraging their unique properties to navigate through complex fluids and reach otherwise inaccessible regions of the human body, thereby enabling new applications in areas such as targeted drug delivery, tissue engineering, and diagnostics. This dissertation develops a

Ferrofluidic microrobots have emerged as promising tools for minimally invasive medical procedures, leveraging their unique properties to navigate through complex fluids and reach otherwise inaccessible regions of the human body, thereby enabling new applications in areas such as targeted drug delivery, tissue engineering, and diagnostics. This dissertation develops a model-predictive controller for the external magnetic manipulation of ferrofluid microrobots. Several experiments are performed to illustrate the adaptability and generalizability of the control algorithm to changes in system parameters, including the three-dimensional reference trajectory, the velocity of the workspace fluid, and the size, orientation, deformation, and velocity of the microrobotic droplet. A linear time-invariant control system governing the dynamics of locomotion is derived and used as the constraints of a least squares optimal control algorithm to minimize the projected error between the actual trajectory and the desired trajectory of the microrobot. The optimal control problem is implemented after time discretization using quadratic programming. In addition to demonstrating generalizability and adaptability, the accuracy of the control algorithm is analyzed for several different types of experiments. The experiments are performed in a workspace with a static surrounding fluid and extended to a workspace with fluid flowing through it. The results suggest that the proposed control algorithm could enable new capabilities for ferrofluidic microrobots, opening up new opportunities for applications in minimally invasive medical procedures, lab-on-a-chip, and microfluidics.
ContributorsSkowronek, Elizabeth Olga (Author) / Marvi, Hamidreza (Thesis advisor) / Berman, Spring (Committee member) / Platte, Rodrigo (Committee member) / Xu, Zhe (Committee member) / Lee, Hyunglae (Committee member) / Arizona State University (Publisher)
Created2023
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Description
This thesis presents a study on the user adaptive variable impedance control of a wearable ankle robot for robot-aided rehabilitation with a primary focus on enhancing accuracy and speed. The controller adjusts the impedance parameters based on the user's kinematic data to provide personalized assistance. Bayesian optimization is employed to

This thesis presents a study on the user adaptive variable impedance control of a wearable ankle robot for robot-aided rehabilitation with a primary focus on enhancing accuracy and speed. The controller adjusts the impedance parameters based on the user's kinematic data to provide personalized assistance. Bayesian optimization is employed to minimize an objective function formulated from the user's kinematic data to adapt the impedance parameters per user, thereby enhancing speed and accuracy. Gaussian process is used as a surrogate model for optimization to account for uncertainties and outliers inherent to human experiments. Student-t process based outlier detection is utilized to enhance optimization robustness and accuracy. The efficacy of the optimization is evaluated based on measures of speed, accuracy, and effort, and compared with an untuned variable impedance controller during 2D curved trajectory following tasks. User effort was measured based on muscle activation data from the tibialis anterior, peroneus longus, soleus, and gastrocnemius muscles. The optimized controller was evaluated on 15 healthy subjects and demonstrated an average increase in speed of 9.85% and a decrease in deviation from the ideal trajectory of 7.57%, compared to an unoptimized variable impedance controller. The strategy also reduced the time to complete tasks by 6.57%, while maintaining a similar level of user effort.
ContributorsManoharan, Gautham (Author) / Lee, Hyunglae (Thesis advisor) / Berman, Spring (Committee member) / Xu, Zhe (Committee member) / Arizona State University (Publisher)
Created2023
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Description
The Soft Robotic Hip Exosuit (SR-HExo) was designed, fabricated, and tested in treadmill walking experiments with healthy participants to gauge effectivity of the suit in assisting locomotion and in expanding the basin of entrainment as a method of rehabilitation. The SR-HExo consists of modular, compliant materials to move freely with

The Soft Robotic Hip Exosuit (SR-HExo) was designed, fabricated, and tested in treadmill walking experiments with healthy participants to gauge effectivity of the suit in assisting locomotion and in expanding the basin of entrainment as a method of rehabilitation. The SR-HExo consists of modular, compliant materials to move freely with a user’s range of motion and is actuated with X-oriented flat fabric pneumatic artificial muscles (X-ff-PAM) that contract when pressurized and can generate 190N of force at 200kPa in a 0.3 sec window. For use in gait assistance experiments, X-ff-PAM actuators were placed anterior and posterior to the right hip joint. Extension assistance and flexion assistance was provided in 10-45% and 50-90% of the gait cycle, respectively. Device effectivity was determined through range of motion (ROM) preservation and hip flexor and extensor muscular activity reduction. While the active suit reduced average hip ROM by 4o from the target 30o, all monitored muscles experienced significant reductions in electrical activity. The gluteus maximus and biceps femoris experienced electrical activity reduction of 13.1% and 6.6% respectively and the iliacus and rectus femoris experienced 10.7% and 27.7% respectively. To test suit rehabilitative potential, the actuators were programmed to apply periodic torque perturbations to induce locomotor entrainment. An X-ff-PAM was contracted at the subject’s preferred gait frequency and, in randomly ordered increments of 3%, increased up to 15% beyond. Perturbations located anterior and posterior to the hip were tested separately to assess impact of location on entrainment characteristics. All 11 healthy participants achieved entrainment in all 12 experimental conditions in both suit orientations. Phase-locking consistently occurred around toe-off phase of the gait cycle (GC). Extension perturbations synchronized earlier in the gait cycle (before 60% GC where peak hip extension occurs) than flexion perturbations (just after 60% GC at the transition from full hip extension to hip flexion), across group averaged results. The study demonstrated the suit can significantly extend the basin of entrainment and improve transient response compared to previously reported results and confirms that a single stable attractor exists during gait entrainment to unidirectional hip perturbations.
ContributorsBaye-Wallace, Lily (Author) / Lee, Hyunglae (Thesis advisor) / Marvi, Hamidreza (Committee member) / Berman, Spring (Committee member) / Arizona State University (Publisher)
Created2021
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Description
The introduction of assistive/autonomous features in cyber-physical systems, e.g., self-driving vehicles, have paved the way to a relatively new field of system analysis for safety-critical applications, along with the topic of controlling systems with performance and safety guarantees. The different works in this thesis explore and design methodologies that focus

The introduction of assistive/autonomous features in cyber-physical systems, e.g., self-driving vehicles, have paved the way to a relatively new field of system analysis for safety-critical applications, along with the topic of controlling systems with performance and safety guarantees. The different works in this thesis explore and design methodologies that focus on the analysis of nonlinear dynamical systems via set-membership approximations, as well as the development of controllers and estimators that can give worst-case performance guarantees, especially when the sensor data containing information on system outputs is prone to data drops and delays. For analyzing the distinguishability of nonlinear systems, building upon the idea of set membership over-approximation of the nonlinear systems, a novel optimization-based method for multi-model affine abstraction (i.e., simultaneous set-membership over-approximation of multiple models) is designed. This work solves for the existence of set-membership over-approximations of a pair of different nonlinear models such that the different systems can be distinguished/discriminated within a guaranteed detection time under worst-case uncertainties and approximation errors. Specifically, by combining mesh-based affine abstraction methods with T-distinguishability analysis in the literature yields a bilevel bilinear optimization problem, whereby leveraging robust optimization techniques and a suitable change of variables result in a sufficient linear program that can obtain a tractable solution with T-distinguishability guarantees. Moreover, the thesis studied the designs of controllers and estimators with performance guarantees, and specifically, path-dependent feedback controllers and bounded-error estimators for time-varying affine systems are proposed that are subject to delayed observations or missing data. To model the delayed/missing data, two approaches are explored; a fixed-length language and an automaton-based model. Furthermore, controllers/estimators that satisfy the equalized recovery property (a weaker form of invariance with time-varying finite bounds) are synthesized whose feedback gains can be adapted based on the observed path, i.e., the history of observed data patterns up to the latest available time step. Finally, a robust kinodynamic motion planning algorithm is also developed with collision avoidance and probabilistic completeness guarantees. In particular, methods based on fixed and flexible invariant tubes are designed such that the planned motion/trajectories can reject bounded disturbances using noisy observations.
ContributorsHassaan, Syed Muhammad (Author) / Yong, Sze Zheng (Thesis advisor) / Rivera, Daniel (Committee member) / Marvi, Hamidreza (Committee member) / Lee, Hyunglae (Committee member) / Berman, Spring (Committee member) / Arizona State University (Publisher)
Created2023