This research addresses the problem of analyzing working conditions of large water systems by means of a detailed hydraulic simulation model (e.g., EPANet) to gain insights into feasibility with respect to pressure, tank level, etc. This work presents a new framework called Feasible Set Approximation – Probabilistic Branch and Bound (FSA-PBnB) for the definition and determination of feasible solutions in terms of pumps regulation. We propose the concept of feasibility distance, which is measured as the distance of the current solution from the feasibility frontier to estimate the distribution of the feasibility values across the solution space. Based on this estimate, pruning the infeasible regions and maintaining the feasible regions are proposed to identify the desired feasible solutions. We test the proposed algorithm with both theoretical and real water networks. The results demonstrate that FSA-PBnB has the capability to identify the feasibility profile in an efficient way. Additionally, with the feasibility distance, we can understand the quality of sub-region in terms of feasibility.
The present work provides a basic feasibility determination framework on the low dimension problems. When FSA-PBnB extends to large scale constraint optimization problems, a more intelligent sampling method may be developed to further reduce the computational effort.
Specifically, this thesis focuses on the formulation of a Markov Chain model that is complex and robust. This Markov Chain model emulates the evolution of MCI patients based upon doctor visits and the sequential administration of biomarker tests. Data provided to create this Markov Chain model were collected by the Alzheimer’s Disease Neuroimaging Initiative (ADNI) database. The data lacked detailed information of the sequential administration of the biomarker tests and therefore, different analytical approaches were tried and conducted in order to calibrate the model. The resulting Markov Chain model provided the capability to conduct experiments regarding different parameters of the Markov Chain and yielded different results of patients that contracted AD and those that did not, leading to important insights into effect of thresholds and sequence on patient prediction capability as well as health costs reduction.
The data in this thesis was provided from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) database (adni.loni.usc.edu). ADNI investigators did not contribute to any analysis or writing of this thesis. A list of the ADNI investigators can be found at: http://adni.loni.usc.edu/about/governance/principal-investigators/ .
In order to design these systems, the Reliability-Based Design Optimization framework using Sequential Optimization and Reliability Assessment (SORA) method is developed. The dynamic nature of component failure probability is considered in the system reliability model. The Stress-Strength Interference (SSI) theory is used to build the limit state functions of components and the First Order Reliability Method (FORM) lies at the heart of reliability assessment. Also, in situations where the user needs to determine the optimum number of components and reduce component redundancy, this method can be used to optimally allocate the required number of components to carry the system load. The main advantage of this method is that the computational efficiency is high and also any optimization and reliability assessment technique can be incorporated. Different cases of numerical examples are provided to validate the methodology.
Time studies are an effective tool to analyze current production systems and propose improvements. The problem that motivated the project was that conducting time studies and observing the progression of components across the factory floor is a manual process. Four Industrial Engineering students worked with a manufacturing company to develop Computer Vision technology that would automate the data collection process for time studies. The team worked in an Agile environment to complete over 120 classification sets, create 8 strategy documents, and utilize Root Cause Analysis techniques to audit and validate the performance of the trained Computer Vision data models. In the future, there is an opportunity to continue developing this product and expand the team’s work scope to apply more engineering skills on the data collected to drive factory improvements.
Time studies are an effective tool to analyze current production systems and propose improvements. The problem that motivated the project was that conducting time studies and observing the progression of components across the factory floor is a manual process. Four Industrial Engineering students worked with a manufacturing company to develop Computer Vision technology that would automate the data collection process for time studies. The team worked in an Agile environment to complete over 120 classification sets, create 8 strategy documents, and utilize Root Cause Analysis techniques to audit and validate the performance of the trained Computer Vision data models. In the future, there is an opportunity to continue developing this product and expand the team’s work scope to apply more engineering skills on the data collected to drive factory improvements.
Time studies are an effective tool to analyze current production systems and propose improvements. The problem that motivated the project was that conducting time studies and observing the progression of components across the factory floor is a manual process. Four Industrial Engineering students worked with a manufacturing company to develop Computer Vision technology that would automate the data collection process for time studies. The team worked in an Agile environment to complete over 120 classification sets, create 8 strategy documents, and utilize Root Cause Analysis techniques to audit and validate the performance of the trained Computer Vision data models. In the future, there is an opportunity to continue developing this product and expand the team’s work scope to apply more engineering skills on the data collected to drive factory improvements.
Time studies are an effective tool to analyze current production systems and propose improvements. The problem that motivated the project was that conducting time studies and observing the progression of components across the factory floor is a manual process. Four Industrial Engineering students worked with a manufacturing company to develop Computer Vision technology that would automate the data collection process for time studies. The team worked in an Agile environment to complete over 120 classification sets, create 8 strategy documents, and utilize Root Cause Analysis techniques to audit and validate the performance of the trained Computer Vision data models. In the future, there is an opportunity to continue developing this product and expand the team’s work scope to apply more engineering skills on the data collected to drive factory improvements.
Covid-19 is unlike any coronavirus we have seen before, characterized mostly by the ease with which it spreads. This analysis utilizes an SEIR model built to accommodate various populations to understand how different testing and infection rates may affect hospitalization and death. This analysis finds that infection rates have a significant impact on Covid-19 impact regardless of the population whereas the impact that testing rates have in this simulation is not as pronounced. Thus, policy-makers should focus on decreasing infection rates through targeted lockdowns and vaccine rollout to contain the virus, and decrease its spread.