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Description
Homeless populations are often disproportionately impacted by several diseases due to factors such as overcrowding, unsanitary conditions, lack of access to healthcare and most importantly lack of education. The purpose of this project was to decrease a part of this health gap by spreading awareness of certain illnesses impacting Arizona’s homeless population and to increase the use plausible prevention methods. This was done through the creation of three simplified brochures that contained information regarding influenza, hepatitis, and schizophrenia. Two surveys were distributed to a local homeless population; the first survey was given prior to handing out the brochures and the second survey was given a week later after the participants had some time to read the information from the brochures. The data from the surveys supported the goal of the project by showing an increase in overall awareness of the diseases as well as an increase in behavioral changes that would lead to the increase of plausible prevention methods.
ContributorsBanuelos, Jason (Author) / Quaranta, Kimberly (Thesis director) / Szeli, Eva (Committee member) / School of Life Sciences (Contributor) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
In recent years, it has become evident that American civic literacy is in a sharp decline. Many scholars agree that young adults are becoming increasingly less engaged in activities involving the application of civics and that this may hinder the democratic process. This thesis will focus on how historical perspectives can improve contemporary application of civics in order to solve the civic literacy crisis. The report will evaluate different approaches to improving civic engagement in order to gauge their effectiveness and the potential for their use in the United States. In analyzing the decline, we will look at work from the American Council of Trustees and Alumni (ACTA) like A Crisis in Civic Education and A Crucible Moment. Subsequently, we will provide a review of Megan McClure’s Tackling the American Civics Education Crisis and Robert D. Putnam’s Bowling Alone: America’s Declining Social Capital. We will present historical perspectives from the 19th and 20th century such as Thomas Jefferson, Alexis De Tocqueville and John Dewey in order to apply them to contemporary solutions for the decline. The contemporary perspectives of Harvard scholar Danielle Allen and various professors in the School of Civic and Economic Thought and Leadership (SCETL) at Arizona State University will be analyzed and critiqued. The results of our research prove that historical perspectives, when applied to contemporary solutions, are an effective way to bout the civic engagement crisis in the United States. This information can be used to alter the curriculum in the classroom to encourage and prepare students to become civically literate and engaged in order to protect the democratic process.
Keywords: civic decline, civic literacy, civic engagement, contemporary, historical
Keywords: civic decline, civic literacy, civic engagement, contemporary, historical
ContributorsBoering, Avery Loren (Co-author) / Giambanco, Niccolo (Co-author) / Seagrave, Adam (Thesis director) / Voboril, Jakub (Committee member) / School of Politics and Global Studies (Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
The combined use of methamphetamine and opioids has been reported to be on the rise throughout the United States (U.S.). However, our knowledge of this phenomenon is largely based upon reported overdoses and overdose-related deaths, law enforcement seizures, and drug treatment records; data that are often slow, restricted, and only track a portion of the population participating in drug consumption activities. As an alternative, wastewater-based epidemiology (WBE) has the capability to track licit and illicit drug trends within an entire community, at a low cost and in near real-time, while providing anonymity to those contributing to the sewer shed. In this study, wastewater was collected from two Midwestern U.S. cities (2017-2019) and analyzed for the prevalence of methamphetamine and the opioids oxycodone, codeine, fentanyl, tramadol, hydrocodone, and hydromorphone. Monthly 24-hour time-weighted composite samples (n = 48) from each city were analyzed using isotope dilution liquid chromatography tandem mass spectrometry. Results showed that methamphetamine and total opioid consumption (milligram morphine equivalents) in City 1 were strongly correlated only in 2017 (Spearman rank order correlation coefficient, ρ = 0.78), the relationship driven by fentanyl, hydrocodone, and hydromorphone. For City 2, methamphetamine and total opioid consumption were strongly positively correlated during the entire study (ρ = 0.54), with the correlations driven by hydrocodone and hydromorphone. In both cities, hydrocodone and hydromorphone mass loads were highly correlated, suggesting a parent and metabolite relationship. WBE provides important insights into licit and illicit drug consumption patterns in near real-time as they evolve; important information for community stakeholders in municipalities across the U.S.
ContributorsClick, Kathleen Grace (Author) / Halden, Rolf (Thesis director) / Gushgari, Adam (Committee member) / Driver, Erin (Committee member) / School of Life Sciences (Contributor) / School of Human Evolution & Social Change (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
In this paper, I aim to assess the ethical and policy issues at the forefront of developmental biology, mainly, the 14-day guideline dictating human embryo research. Ever since the invention of in vitro fertilization in the 1970s, the research landscape of human embryo research has been well explored. Now, there are new embryonic technologies and human embryonic stem cell based models that many believe do not fit into current guidelines. This paper analyzes four of these new technologies-- stem cell derived gametes, embryoids, 3D printed embryos and synthetic embryos-- in order to explore the impetus for reopening the debate on the 14-day guideline. The paper then explores current research and research projects while comparing and contrasting science as well as the potential for moral status and how that impacts regulation. Current United States policies and regulations as well as current professional society guidelines are broken down to fully grasp the political landscape surrounding human embryo research. Notably, current policies include the complete lack of a federal definition of an embryo as well as the Dickey-Wicker Amendment which restrict funding for human embryo research. It is thus advised that these, along with the 14 day guideline, are updated in order to encapsulate the early human developmental research landscape and promote research. This paper ends with an in depth policy recommendation including (but not limited to) bill language, suggested definitions and potential strategies.
ContributorsNadone, Haley (Author) / Robert, Jason (Thesis director) / Frow, Emma (Committee member) / School of Life Sciences (Contributor) / School of Politics and Global Studies (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
Hyperspectral imaging is a novel technology which allows for the collection of reflectance spectra of a sample in-situ and at a distance. A rapidly developing technology, hyperspectral imaging has been of particular interest in the field of art characterization, authentication, and conservation as it avoids the pitfalls of traditional characterization techniques and allows for the rapid and wide collection of data never before possible. It is hypothesized that by combining the power of hyperspectral imaging with machine learning, a new framework for the in-situ and automated characterization and authentication of artworks can be developed. This project, using the CMYK set of inks, began the preliminary development of such a framework. It was found that hyperspectral imaging and machine learning as a combination show significant potential as an avenue for art authentication, though further progress and research is needed to match the reliability of status quo techniques.
ContributorsChowdhury, Tanzil Aziz (Author) / Newman, Nathan (Thesis director) / Tongay, Sefaattin (Committee member) / School of Politics and Global Studies (Contributor) / Materials Science and Engineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
Persons with cystic fibrosis (CF) are highly susceptible to lung infections caused by the opportunistic pathogens Pseudomonas aeruginosa (PA) and Staphylococcus aureus (SA). By age 20, ~16% of CF patients have co-infections with these two bacteria, and this number grows as the patients age1. PA-SA co-infections are associated with worsened clinical outcomes in CF patients, but the reasons are not well understood. One hypothesis is that SA influences the production of PA virulence factors and other chronic infection phenotypes. Previous work in our lab investigated the effects of SA on PA quorum-regulated phenotypes when they are grown as planktonic co-cultures. We are expanding on this result by testing whether SA can influence PA phenotypes without being in direct contact, and without being able to exchange soluble secreted factors. In this study, we hypothesized that SA produces volatile organic compounds (VOCs) that cause changes in PA phenotypes leading to a down-regulation of motility and protease production, and increased antibiotic resistance. To test this hypothesis, we exposed two laboratory strains of PA to the VOCs produced by pre-grown lawns of two strains of SA, and measured PA motility by conducting swarming, swimming, and twitching assays, measuring protease production, as well as antibiotic sensitivity. After exposing PA to a pre-grown lawn of SA, there was a significant difference in some phenotypes compared to controls. There were significant decreases in swarming motility, twitching motility, and protease production, and an increase in a bright green pigment (possibly siderophores) when PA was exposed to SA. The degree of phenotypic alterations was dependent on both the PA strain and the SA strain being tested. Exposure to SA VOCs also altered PA sensitivity to ciprofloxacin, though one strain caused an increase in susceptibility while the other SA strain caused an increase in resistance. These data demonstrate that SA VOCs can influence PA phenotypes in vitro, which may have relevance for CF patients who are co-infected with these two bacteria.
ContributorsLopez, Brianna Marie (Author) / Bean, Heather (Thesis director) / Misra, Rajeev (Committee member) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
This thesis explored the psychometric properties of an ASU midterm. These analyses were done to explore the efficacy of the questions on the exam using the methods of item analysis difficulty and discrimination. The discrimination and difficulty scores as well as the correlations of questions led to suggests of questions that may need revision.
ContributorsLowell, Emily M (Author) / Levy, Roy (Thesis director) / O'Rourke, Holly (Committee member) / School of Life Sciences (Contributor) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
The brain is considered the crux of identity, yet human behavior may be influenced by bacteria in gut microbiomes. Honeybees can exchange bacteria through their many social behaviors, making their microbiomes, and the effect they have on honeybee behavior, of interest. There is recent evidence suggesting the presence of bacteria existing in human brains, which can be investigated in honeybee brains due to their well-documented structure. The purpose of this study is to establish if lipopolysaccharide—a molecule on bacteria membranes—is present in the honeybee brain and if it colocalizes with vitellogenin—an immune mediator. Additionally, this study also seeks to establish the efficacy of embedding tissue samples in resin and performing immunohistochemistry for vitellogenin and lipopolysaccharide on sections.
ContributorsStrange, Amalie Sofie (Co-author) / Strange, Amalie (Co-author) / Amdam, Gro (Thesis director) / Baluch, Page (Committee member) / School of International Letters and Cultures (Contributor) / School of Life Sciences (Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
Bone is an active tissue that is vital for many important bodily functions including providing support and structure, facilitating movement, producing blood cells, and storing and releasing minerals and fat. Bone is actively remodeling by resorbing old bone and forming new bone. These processes are carried about by osteoblasts and osteoclasts. When there is a balance between the processes of bone remodeling, resorption and formation, in adults, bone density is maintained and healthy. However, when bone resorption occurs at a greater rate than bone formation, bone density is reduced. This can be caused as a side effect of disease, such as the case in diabetes, or as a result of disease, such as osteoporosis. Bone health can be assessed several different ways including through dual-energy X-ray absorptiometry (DXA) scans to determine and monitor bone mineral density (BMD) or through protein assays of bone turnover marker (BTMs) to look directly at the different biochemical markers of bone remodeling. Measurement of BMD and BTM both have their benefits and downsides and a combination of both is most ideal for obtaining a holistic view of an individual’s bone health and remodeling.
ContributorsFuentes, Braegen (Author) / Swan, Dr. Pamela (Thesis director) / Johnston, Dr. Carol (Committee member) / School of Life Sciences (Contributor) / School of Art (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
This paper aims to effectively portray the stories of migrant laborers who have fallen victim to a system of powerful and exploitative institutions and governments that provide labor for the FIFA 2022 World Cup in Qatar. The purpose of this case study, therefore, is to both uncover the causes and magnitude of the crisis and to understand the relationship between the victimized laborers and the perpetrators. Through this study, I present the complex dynamics of a mass geopolitical operation that leads to the victimization of Nepali workers. I specifically outline why this issue is complicated and what the proper interventions may be to resolve it.
ContributorsNyaupane, Pratik (Co-author) / Kassing, Jeffrey W. (Thesis director) / Dutta, Uttaran (Committee member) / School of Politics and Global Studies (Contributor) / Computer Science and Engineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05