Matching Items (33)
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Public engagement is increasingly viewed as an important pillar of scientific scholarship. For early career and established scholars, however, navigating the mosaic landscape of public education and science communication, noted for rapid “ecological” succession, can be daunting. Moreover, academics are characterized by diverse skills, motivations, values, positionalities, and temperaments that

Public engagement is increasingly viewed as an important pillar of scientific scholarship. For early career and established scholars, however, navigating the mosaic landscape of public education and science communication, noted for rapid “ecological” succession, can be daunting. Moreover, academics are characterized by diverse skills, motivations, values, positionalities, and temperaments that may differentially incline individuals to particular public translation activities.

ContributorsAmorim, Carlos Eduardo G (Author) / Dasari, Mauna (Author) / Durgavich, Lara (Author) / Hinde, Katie (Author) / Kissel, Marc (Author) / Lewton, Kristi L (Author) / Loewen, Tisa (Author)
Created2021
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Behavior of males and females may be mediated by their biological differences and, among cercopithecines, their divergent reproductive strategies. In order to have high reproductive success, individuals need to produce high quality offspring. Through pregnancy, lactation, and maternal care, females have a strong influence on the quality of their offspring.

Behavior of males and females may be mediated by their biological differences and, among cercopithecines, their divergent reproductive strategies. In order to have high reproductive success, individuals need to produce high quality offspring. Through pregnancy, lactation, and maternal care, females have a strong influence on the quality of their offspring. Within the cercopithecine mating system, males are limited in direct influence on offspring outcomes within the Cercopithecines, and are adapted to more typically maximize mating opportunities. In general, female reproductive strategies involve securing the most food while male reproductive strategies are geared towards helping them secure the most fertile females both somatically and behaviorally. In this paper, I investigated how the behaviors observed among female adolescent rhesus macaque monkeys would differ from the males as their divergent reproductive trajectories begin to manifest. I made predictions based off of four questions: who would be more affiliative with whom, who would be more aggressive and with whom, who would be more variable in their behaviors, and who would be lonelier. I predicted that females would be more affiliative with other females, due to the importance of social connectivity, and males would be more affiliative with males, due to the social bonds male adolescents form with each other. I predicted that males would be overall more aggressive than males because they were found to be by Bernstein et al. (1993). I predicted that males would show more variation in behavior since they may have to be more flexible to capitalize on all conditions to obtain mates. Finally, I predicted that males would be lonelier as an effect of social rank on males and female choice. In order to further understand these differences, 36 adolescent Macaca mulatta, N = 20 female and N=16 male, from the California Primate Center at University of California at Davis, CA were observed. The observer used a standardized method to score the subjects on a variety of behaviors like locomotion, aggression, grooming and more. Each individual underwent around 6 trials and the observations lasted 15 minutes. The data supported the first hypothesis that females are affiliative with each other and males are affiliative with each other. The date also showed that females are more aggressive than males and their aggression is generally targeted towards females. The third prediction was not supported by the data and females were actually more variable in their behaviors than males. Lastly, the data did not support the prediction that males are lonely moneys, however, it did support the alternative hypothesis that they are truly low sociable, low in sociability and low social connectivity.
ContributorsVasquez Urias, Rubi (Author) / Hinde, Katie (Thesis director) / Johnson, Caley (Committee member) / School of International Letters and Cultures (Contributor) / School of Human Evolution and Social Change (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
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Human milk contains essential micronutrients for growth and development during early life. Environmental pollutants, such as potentially toxic metals, can also be transferred to the infant through human milk. These elements have been well-studied, but changing diets and environments and advances in laboratory technology require re-examining these elements in a

Human milk contains essential micronutrients for growth and development during early life. Environmental pollutants, such as potentially toxic metals, can also be transferred to the infant through human milk. These elements have been well-studied, but changing diets and environments and advances in laboratory technology require re-examining these elements in a variety of settings. The aim of this study was to characterize the concentrations of essential and toxic metals in human milk from four diverse populations. Human milk samples (n = 70) were collected in Argentina (n = 21), Namibia (n = 6), Poland (n = 23), and the United States (n = 20) using a standardized mid-feed collection procedure. Milk concentrations of calcium, zinc, iron, copper, manganese, lead, arsenic, and cadmium were determined using inductively coupled plasma mass spectrometry (ICP-MS). We used standard multiple linear regression models to evaluate differences among populations, while including infant age, infant sex, and maternal parity status (multiparous or primiparous) as covariates. Concentrations of all elements, except zinc, varied across populations after controlling for infant age, infant sex, and maternal parity. Calcium and magnesium showed more differences across populations than iron or copper. There were no significant differences among population in zinc concentrations. Mean concentrations of lead, but not arsenic, were low compared to recently published values from other populations. The concentrations of trace elements in human milk are variable among populations. Limitations due to small sample sizes and environmental contamination of some samples prevent us from drawing robust conclusions about the causes of these differences.

ContributorsKlein, Laura D. (Author) / Breakey, Alicia A. (Author) / Scelza, Brooke (Author) / Valeggia, Claudia (Author) / Jasienska, Grazyna (Author) / Hinde, Katie (Author) / College of Liberal Arts and Sciences (Contributor)
Created2017-08-17
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Description

Social monogamy at its most basic is a group structure in which two adults form a unit and share a territory. However, many socially monogamous pairs display attachment relationships known as pair bonds, in which there is a mutual preference for the partner and distress upon separation. The neural and

Social monogamy at its most basic is a group structure in which two adults form a unit and share a territory. However, many socially monogamous pairs display attachment relationships known as pair bonds, in which there is a mutual preference for the partner and distress upon separation. The neural and hormonal basis of this response to separation from the adult pair mate is under-studied. In this project, we examined this response in male titi monkeys (Callicebus cupreus), a socially monogamous New World primate. Males underwent a baseline scan, a short separation (48 h), a long separation (approximately 2 weeks), a reunion with the female pair mate and an encounter with a female stranger (with nine males completing all five conditions). Regional cerebral glucose metabolism was measured via positron emission tomography (PET) imaging using [18F]-fluorodeoxyglucose (FDG) co-registered with structural magnetic resonance imaging (MRI), and region of interest (ROI) analysis was carried out. In addition, plasma was collected and assayed for cortisol, oxytocin (OT), vasopressin (AVP), glucose and insulin concentrations. Cerebrospinal fluid (CSF) was collected and assayed for OT and AVP.

We used generalized estimating equations (GEE) to examine significant changes from baseline. Short separations were characterized by decreases in FDG uptake, in comparison to baseline, in the lateral septum (LS), ventral pallidum (VP), paraventricular nucleus of the hypothalamus (PVN), periaqueductal gray (PAG), and cerebellum, as well as increases in CSF OT, and plasma cortisol and insulin. Long separations differed from baseline in reduced FDG uptake in the central amygdala (CeA), reduced whole brain FDG uptake, increased CSF OT and increased plasma insulin. The response on encounter with a stranger female depended on whether or not the male had previously reproduced with his pair mate, suggesting that transitions to fatherhood contribute to the neurobiology underlying response to a novel female. Reunion with the partner appeared to stimulate coordinated release of central and peripheral OT. The observed changes suggest the involvement of OT and AVP systems, as well as limbic and striatal areas, during separation and reunion from the pair mate.

ContributorsHinde, Katie (Author) / Muth, Chelsea (Author) / Maninger, Nicole (Author) / Ragen, Benjamin J. (Author) / Larke, Rebecca H. (Author) / Jarcho, Michael R. (Author) / Mendoza, Sally P. (Author) / Mason, William A. (Author) / Ferrer, Emilio (Author) / Cherry, Simon R. (Author) / Fisher-Phelps, Marina L. (Author) / Bales, Karen L. (Author) / College of Liberal Arts and Sciences (Contributor)
Created2016-11-14
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Nursing behavior is notoriously difficult to study in arboreal primates, particularly when offspring suckle inconspicuously in nests. Orangutans have the most prolonged nursing period of any mammal, with the cessation of suckling (weaning) estimated to occur at 6 to 8 years of age in the wild. Milk consumption is hypothesized

Nursing behavior is notoriously difficult to study in arboreal primates, particularly when offspring suckle inconspicuously in nests. Orangutans have the most prolonged nursing period of any mammal, with the cessation of suckling (weaning) estimated to occur at 6 to 8 years of age in the wild. Milk consumption is hypothesized to be relatively constant over this period, but direct evidence is limited. We previously demonstrated that trace element analysis of bioavailable elements from milk, such as barium, provides accurate estimates of early-life diet transitions and developmental stress when coupled with growth lines in the teeth of humans and nonhuman primates. We provide the first detailed nursing histories of wild, unprovisioned orangutans (Pongo abelii and Pongo pygmaeus) using chemical and histological analyses. Laser ablation inductively coupled plasma mass spectrometry was used to determine barium distributions across the teeth of four wild-shot individuals aged from postnatal biological rhythms. Barium levels rose during the first year of life in all individuals and began to decline shortly after, consistent with behavioral observations of intensive nursing followed by solid food supplementation. Subsequent barium levels show large sustained fluctuations on an approximately annual basis. These patterns appear to be due to cycles of varying milk consumption, continuing until death in an 8.8-year-old Sumatran individual. A female Bornean orangutan ceased suckling at 8.1 years of age. These individuals exceed the maximum weaning age reported for any nonhuman primate. Orangutan nursing may reflect cycles of infant demand that relate to fluctuating resource availability.

ContributorsSmith, Tanya M. (Author) / Austin, Christine (Author) / Hinde, Katie (Author) / Vogel, Erin R. (Author) / Arora, Manish (Author) / College of Liberal Arts and Sciences (Contributor)
Created2017-05-17
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Description

Background: Accumulating evidence indicates interactions between human milk composition, particularly sugars (human milk oligosaccharides or HMO), the gut microbiota of human infants, and behavioral effects. Some HMO secreted in human milk are unable to be endogenously digested by the human infant but are able to be metabolized by certain species of

Background: Accumulating evidence indicates interactions between human milk composition, particularly sugars (human milk oligosaccharides or HMO), the gut microbiota of human infants, and behavioral effects. Some HMO secreted in human milk are unable to be endogenously digested by the human infant but are able to be metabolized by certain species of gut microbiota, including Bifidobacterium longum subsp. infantis (B. infantis), a species sensitive to host stress (Bailey & Coe, 2004). Exposure to gut bacteria like B. infantisduring critical neurodevelopment windows in early life appears to have behavioral consequences; however, environmental, physical, and social stress during this period can also have behavioral and microbial consequences. While rodent models are a useful method for determining causal relationships between HMO, gut microbiota, and behavior, murine studies of gut microbiota usually employ oral gavage, a technique stressful to the mouse. Our aim was to develop a less-invasive technique for HMO administration to remove the potential confound of gavage stress. Under the hypothesis that stress affects gut microbiota, particularly B. infantis, we predicted the pups receiving a prebiotic solution in a less-invasive manner would have the highest amount of Bifidobacteria in their gut.

Methods: This study was designed to test two methods, active and passive, of solution administration to mice and the effects on their gut microbiome. Neonatal C57BL/6J mice housed in a specific-pathogen free facility received increasing doses of fructooligosaccharide (FOS) solution or deionized, distilled water. Gastrointestinal (GI) tracts were collected from five dams, six sires, and 41 pups over four time points. Seven fecal pellets from unhandled pups and two pellets from unhandled dams were also collected. Qualitative real-time polymerase chain reaction (qRT-PCR) was used to quantify and compare the amount of Bifidobacterium, Bacteroides, Bacteroidetes, and Firmicutes.

Results: Our results demonstrate a significant difference between the amount of Firmicutes in pups receiving water passively and those receiving FOS actively (p-value = 0.009). Additionally, we found significant differences between the fecal microbiota from handled and non-handled mouse pups.

Discussion: From our results, we conclude even handling pups for experimental purposes, without gavage, may induce enough stress to alter the murine gut microbiota profile. We suggest further studies to examine potential stress effects on gut microbiota caused by experimental techniques. Stress from experimental techniques may need to be accounted for in future gut microbiota studies.

ContributorsAllen-Blevins, Cary R. (Author) / You, Xiaomeng (Author) / Hinde, Katie (Author) / Sela, David A. (Author) / College of Liberal Arts and Sciences (Contributor)
Created2017-01-11
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Early life stress can disrupt development and negatively impact long-term health trajectories. Reconstructing histories of early life exposure to external stressors is hampered by the absence of retrospective time-specific biomarkers. Defects in tooth enamel have been used to reconstruct stress but the methods used are subjective and do not identify

Early life stress can disrupt development and negatively impact long-term health trajectories. Reconstructing histories of early life exposure to external stressors is hampered by the absence of retrospective time-specific biomarkers. Defects in tooth enamel have been used to reconstruct stress but the methods used are subjective and do not identify the specific biological systems impacted by external stressors. Here we show that external physical and social stressors impart biochemical signatures in primate teeth that can be retrieved to objectively reconstruct the timing of early life developmental disruptions. Using teeth from captive macaques, we uncovered elemental imprints specific to disruptions of skeletal growth, including major disruptions in body weight trajectory and moderate to severe illnesses. Discrete increases in heat shock protein-70 expression in dentine coincided with elemental signatures, confirming that elemental signals were associated with activation of stress-related pathways. To overcome limitations of conventional light-microscopic analysis, we used high resolution Raman microspectral imaging to identify structural and compositional alterations in enamel and dentine that coincided with elemental signatures and with detailed medical and behavioural data. Integrating these objective biochemical markers with temporal mapping of teeth enables the retrospective study of early life developmental disruptions and their ensuing health sequelae.

ContributorsAustin, Christine (Author) / Smith, Tanya M. (Author) / Farahani, Ramin M. Z. (Author) / Hinde, Katie (Author) / Carter, Elizabeth A. (Author) / Lee, Joonsup (Author) / Lay, Peter A. (Author) / Kennedy, Brendan J. (Author) / Sarrafpour, Babak (Author) / Wright, Rosalind J. (Author) / Wright, Robert O. (Author) / Arora, Manish (Author) / College of Liberal Arts and Sciences (Contributor)
Created2016-01-04
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ContributorsHinde, Katie (Author) / Kissel, Jenna (Author) / Hecht, Ian (Author) / Gabrys, Jennifer (Author) / Brunstrum, Jeff (Author) / Schuttler, Stephanie (Author) / Chestnut, Tara (Author) / Mahmoud, Marwa (Author)
Created2022-02
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This lesson plan was created by Prof. Katie Hinde, Arizona State University, using Next Generation Science Standards and explanations from the National Academies of Sciences, Engineering, and Medicine. 2012. A Framework for K-12 Science Education: Practices, Crosscutting Concepts, and Core Ideas. Washington, DC: The National Academies Press. https://doi.org/10.17226/13165.

ContributorsHinde, Katie (Creator)
Created2022
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Description

This lesson plan was created by Prof. Katie Hinde, Arizona State University, using Next Generation Science Standards and explanations from the National Academies of Sciences, Engineering, and Medicine. 2012. A Framework for K-12 Science Education: Practices, Crosscutting Concepts, and Core Ideas. Washington, DC: The National Academies Press. https://doi.org/10.17226/13165.

ContributorsHinde, Katie (Creator)
Created2022