Underreporting of energy intake (EI) has been found to be an important consideration that interferes with accurate weight control assessment and the effective use of energy balance (EB) models in an intervention setting. To better understand underreporting, a variety of estimation approaches are developed; these include back-calculating energy intake from a closed-form of the EB model, a Kalman-filter based algorithm for recursive estimation from randomly intermittent measurements in real time, and two semi-physical identification approaches that can parameterize the extent of systematic underreporting with global/local modeling techniques. Each approach is analyzed with intervention participant data and demonstrates potential of promoting the success of weight control.
In addition, substantial efforts have been devoted to develop participant-validated models and incorporate into the Hybrid Model Predictive Control (HMPC) framework for closed-loop interventions. System identification analyses from Phase I led to modifications of the measurement protocols for Phase II, from which longer and more informative data sets were collected. Participant-validated models obtained from Phase II data significantly increase predictive ability for individual behaviors and provide reliable open-loop dynamic information for HMPC implementation. The HMPC algorithm that assigns optimized dosages in response to participant real time intervention outcomes relies on a Mixed Logical Dynamical framework which can address the categorical nature of dosage components, and translates sequential decision rules and other clinical considerations into mixed-integer linear constraints. The performance of the HMPC decision algorithm was tested with participant-validated models, with the results indicating that HMPC is superior to "IF-THEN" decision rules.
The U.S. Navy and other amphibious military organizations utilize a derivation of the traditional side stroke called the Combat Side Stroke, or CSS, and tout it as the most efficient technique available. Citing its low aerobic requirements and slow yet powerful movements as superior to the traditionally-best front crawl (freestyle), the CSS is the go-to stroke for any operation in the water. The purpose of this thesis is to apply principles of Industrial Engineering to a real-world situation not typically approached from a perspective of optimization. I will analyze pre-existing data about various swim strokes in order to compare them in terms of efficiency for different variables. These variables include calories burned, speed, and strokes per unit distance, as well as their interactions. Calories will be measured by heart rate monitors, converting BPM to calories burned. Speed will be measured by stopwatch and observer. Strokes per unit distance will be measured by observer. The strokes to be analyzed include the breast stroke, crawl stroke, butterfly, and combat side stroke. The goal is to informally test the U.S. Navy's claim that the combat side stroke is the optimum stroke to conserve energy while covering distance. Because of limitations in the scope of the project, analysis will be done using data collected from literary sources rather than through experimentation. This thesis will include a design of experiment to test the findings here in practical study. The main method of analysis will be linear programming, followed by hypothesis testing, culminating in a design of experiment for future progress on this topic.