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The impact of musical theatre in the United States calls attention to its role in our cultural heritage. Art in all its forms has always been considered to be something of an ongoing history of a society's culture. Musical theatre has been very successful in synthesizing several different aspects of

The impact of musical theatre in the United States calls attention to its role in our cultural heritage. Art in all its forms has always been considered to be something of an ongoing history of a society's culture. Musical theatre has been very successful in synthesizing several different aspects of American culture and establishing historical markers in areas of music, drama, social issues, and even technology. The plethora of issues challenged by pieces of music theatre has created a large canon of works that contribute greatly to our culture, both artistically and socially. These works are the result of many centuries of artistic performance and the evolution that these works have gone through over time. Tracing back through vaudeville, Follies, and into the works of European opera: musical theatre has a rich and extensive background in production styles that still inform its presentation today. These styles allow for a dynamic presentation of the ideas and issues that music theatre wishes to address and challenge. When the production style and content of musical works are drawn from these past sources, the oral traditions and storytelling aspects of these works gain renewed prominence. Music theatre as a new frontier of literary study warrants further investigation into its literary merit.
ContributorsMcNay, Michael (Author) / Dreyfoos, Dale (Thesis director) / Harper, Robert (Committee member) / Yatso, Toby (Committee member) / Barrett, The Honors College (Contributor) / College of Liberal Arts and Sciences (Contributor)
Created2012-12
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Description
The deficiency of American primary and secondary schools as compared to schools worldwide has long been documented. The Teaching Gap highlights exactly where our problems might lie, and lays out a plan for how to deal with it. Progress would be slow, but tangible. Our country, however, seems to prefer

The deficiency of American primary and secondary schools as compared to schools worldwide has long been documented. The Teaching Gap highlights exactly where our problems might lie, and lays out a plan for how to deal with it. Progress would be slow, but tangible. Our country, however, seems to prefer vast and immediate overhauls that have historically failed (see: New math, etc.). If we had implemented the changes in The Teaching Gap in the decade in which it was written, we would be seeing results by now. Instead, every change we make gets reverted. The Common Core State Standards will prove over the next few years to be either another one of these attempts or a large step in the right direction. It might finally be the latter, as its creation was informed by practices that work best in every state in the US, as well as high- performing countries around the world.
ContributorsMcKee, Emily (Author) / Sande, V. Carla (Thesis director) / Ashbrook, Mark (Committee member) / Schroeder, Darcy (Committee member) / Barrett, The Honors College (Contributor) / College of Liberal Arts and Sciences (Contributor)
Created2012-12
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Description
Civil society, when taken as a whole, is a complex phenomenon that incorporates several movements and can be accompanied with international support. For instance in 1987, 40 NGOs (non-governmental organizations) were registered by the government, and within 25 years, the number has increased to 300,000 in the present day Russian

Civil society, when taken as a whole, is a complex phenomenon that incorporates several movements and can be accompanied with international support. For instance in 1987, 40 NGOs (non-governmental organizations) were registered by the government, and within 25 years, the number has increased to 300,000 in the present day Russian Federation. These numbers only include registered organizations, and do not count unregistered organizations, as approved under article 3 "Public organizations...can function without state registration and acquiring of the rights of registered legal body," or organizations that have been refused registration, such as the "Marriage Equality Russia" NGO that was denied registration in 2010. Thus the total amount of NGOs is significantly higher than 300,000. Every one of these NGOs "contribute to Russia‘s economic, political and social life in numerous ways and provide opportunities for citizens to help create better communities and elevate their voices" ("USAID in Russia"). With hundreds of thousands of organizations attempting to make a better society, they are creating a Russian civil society, one that could use the experience of countries with already well-established civil societies (Walzer). Walzer, however, notes the importance for civil society of political engagement with the state (317). In this thesis, I argue that the LGBT movement in Russia today has set an important example for other groups in civil society through its willingness to take on the Russian state through demonstrations and to use the state through the EU Court of Human Rights in Strasbourg.
ContributorsMark, Daniel (Author) / Hoogenboom, Hilde (Thesis director) / Hagen, V. Mark (Committee member) / Siroky, David (Committee member) / Barrett, The Honors College (Contributor) / College of Liberal Arts and Sciences (Contributor)
Created2012-12
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Description
Glioblastoma multiforme (GBMs) is the most prevalent brain tumor type and causes approximately 40% of all non-metastic primary tumors in adult patients [1]. GBMs are malignant, grade-4 brain tumors, the most aggressive classication as established by the World Health Organization and are marked by their low survival rate; the median

Glioblastoma multiforme (GBMs) is the most prevalent brain tumor type and causes approximately 40% of all non-metastic primary tumors in adult patients [1]. GBMs are malignant, grade-4 brain tumors, the most aggressive classication as established by the World Health Organization and are marked by their low survival rate; the median survival time is only twelve months from initial diagnosis: Patients who live more than three years are considered long-term survivors [2]. GBMs are highly invasive and their diffusive growth pattern makes it impossible to remove the tumors by surgery alone [3]. The purpose of this paper is to use individual patient data to parameterize a model of GBMs that allows for data on tumor growth and development to be captured on a clinically relevant time scale. Such an endeavor is the rst step to a clinically applicable predictions of GBMs. Previous research has yielded models that adequately represent the development of GBMs, but they have not attempted to follow specic patient cases through the entire tumor process. Using the model utilized by Kostelich et al. [4], I will attempt to redress this deciency. In doing so, I will improve upon a family of models that can be used to approximate the time of development and/or structure evolution in GBMs. The eventual goal is to incorporate Magnetic Resonance Imaging (MRI) data into a parameterized model of GBMs in such a way that it can be used clinically to predict tumor growth and behavior. Furthermore, I hope to come to a denitive conclusion as to the accuracy of the Koteslich et al. model throughout the development of GBMs tumors.
ContributorsManning, Miles (Author) / Kostelich, Eric (Thesis director) / Kuang, Yang (Committee member) / Preul, Mark (Committee member) / Barrett, The Honors College (Contributor) / College of Liberal Arts and Sciences (Contributor)
Created2012-12
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Description
Identifying associations between genotypes and gene expression levels using next-generation technology has enabled systematic interrogation of regulatory variation underlying complex phenotypes. Understanding the source of expression variation has important implications for disease susceptibility, phenotypic diversity, and adaptation (Main, 2009). Interest in the existence of allele-specific expression in autosomal genes evolved

Identifying associations between genotypes and gene expression levels using next-generation technology has enabled systematic interrogation of regulatory variation underlying complex phenotypes. Understanding the source of expression variation has important implications for disease susceptibility, phenotypic diversity, and adaptation (Main, 2009). Interest in the existence of allele-specific expression in autosomal genes evolved with the increased awareness of the important role that variation in non-coding DNA sequences can play in determining phenotypic diversity, and the essential role parent-of-origin expression has in early development (Knight, 2004). As new implications of high-throughput sequencing are conceived, it is becoming increasingly important to develop statistical methods tailored to large and formidably complex data sets in order to maximize the biological insights derived from next-generation sequencing experiments. Here, a Bayesian hierarchical probability model based on the beta-binomial distribution is proposed as a possible approach for quantifying allele-specific expression from whole genome (WGS) and whole transcriptome (RNA-seq) data. Pipeline for the analysis of WGS and RNA-seq data sets from ten samples was developed and implemented, while allele-specific expression (ASE) was quantified from both haplotypes using individuals heterozygous at the tested variants utilizing the described methodology. Both computational and statistical framework applied accurately quantified ASE, achieving high reproducibility of already described allele-specific genes in the literature. In conclusion, described methodology provides a solid starting point for quantifying allele specific expression across whole genomes.
ContributorsMalenica, Ivana (Author) / Craig, David (Thesis director) / Rosenberg, Michael (Committee member) / Szelinger, Szabolcs (Committee member) / Barrett, The Honors College (Contributor) / College of Liberal Arts and Sciences (Contributor)
Created2012-12
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Description
It has been 30 years since research has tried to determine how adults decide if an infant is male or female (Seavey et al., 1975; Sidorowicz & Lunney, 1980), with research at that time indicating that participants tended to label infants as male. The purpose of this study is to

It has been 30 years since research has tried to determine how adults decide if an infant is male or female (Seavey et al., 1975; Sidorowicz & Lunney, 1980), with research at that time indicating that participants tended to label infants as male. The purpose of this study is to investigate whether adults today can identify infant gender above chance, and what tools adults use to assign gender labels to babies. I hypothesize that females, social science majors, students who frequently interact with children, and students who are very confident will all assign gender labels more accurately than their counterparts. I showed a video to University students featuring five sets of parents playing with their infants. The video featuring three male and two female babies was edited to remove any gender identifying information. Students were asked to guess whether each of the infants was male or female, and to explain how they came to that conclusion. One sample t-tests revealed that students overall were able to correctly identify infant gender significantly more than what would be expected due to chance for 4 out of 5 infants. The results did not support my hypothesis that social science majors or people who frequently interact with children are better at assigning gender labels. This study did find a significant correlation between confidence and accuracy. When asked to explain how participants assigned infant gender labels, I found a significant correlation between infant physical movement and correct students labeling the infant as male. There was also a significant relationship between parental voice being and participants labeling infants as female whether the infant was actually female or not. Unlike research from the late 1970's and early 1980's, college students today can accurately assign gender labels to infants. This suggests that either the conceptualization of gender in the U.S. culture has changed enough since previous research over 3 decades ago, that there is something about parent-baby play that helps people correctly identify infant gender, or both.
ContributorsLove, Echo (Author) / Shapiro, Alyson (Thesis director) / Mikulski, Ariana (Committee member) / Martin, Carol (Committee member) / Barrett, The Honors College (Contributor) / College of Liberal Arts and Sciences (Contributor)
Created2012-12
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Description
Capstone project, I began developing an animated series called Legends of Gaia. The show follows a small group of people of mixed ages and backgrounds, as they travel across the world trying to stop the Galliean Empire, a technologically booming western power that has begun fighting a war for world

Capstone project, I began developing an animated series called Legends of Gaia. The show follows a small group of people of mixed ages and backgrounds, as they travel across the world trying to stop the Galliean Empire, a technologically booming western power that has begun fighting a war for world domination. The purpose of this paper is to better explain the origins and inspirations of the mythology of my series, as well as the major two supernatural characters of my series, and the general geography (both physical and metaphysical) of the series. When first developing this series, I looked into the works of Joseph Campbell, as he wrote the book(s) on mythology in many ways. His most famous writings are probably the Hero's Journey and the Monomyth, the basic outline of the journey that most heroes go through, from the call ordinary world, to the call of the adventure, all the way to the hero returning (Campbell 211). Many classic examples of story telling follow the pattern Campbell outlined, and my work is no exception. However, I did not want my series to be a beat for beat retread of the Hero's Journey, and so some parts, such as the Refusal of the Call, when the hero rejects the adventure and befalls a tragedy, were skipped, while others, such as the resurrection, were realized in different ways. Using the Resurrection as an example, in my series the main female character, Diana is reborn twice throughout the series. Once in the final battle with the main villain into her true, goddess form, and the other when her battles are over, and she is reborn in her mortal form permanently.
ContributorsLopez, Richard (Author) / Collis, Adam (Thesis director) / Valenti, F. Miguel (Committee member) / Barzso, Tain (Committee member) / Barrett, The Honors College (Contributor) / Herberger Institute for Design and the Arts (Contributor) / College of Liberal Arts and Sciences (Contributor)
Created2012-12
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Description
The front cover of Uncle What-Is-It is Coming to Visit, a 1993 children’s book by Michael-Willhoite, features two white children frightened by the hairy arm and upturned wrist of an unseen adult. The arm is clad in a frilly pink and orange sleeve, and gaudy bracelets hang from the wrist.

The front cover of Uncle What-Is-It is Coming to Visit, a 1993 children’s book by Michael-Willhoite, features two white children frightened by the hairy arm and upturned wrist of an unseen adult. The arm is clad in a frilly pink and orange sleeve, and gaudy bracelets hang from the wrist. The plot hinges on the children’s uncertainty about an uncle they have yet to meet; they know he is gay but are unsure of what it means. Before their mother can explain, she is distracted by a kitchen mishap and the siblings turn to other neighborhood children for answers. They encounter a host of descriptions that terrify them: one neighbor describes gay people as “fags [and] queers [who] really want to be women.” He shows the children a newspaper clipping photo of “a large man dressed in a frilly dress [with] a turban piled high with fruit on his head,” an implicitly racialized caricature reminiscent of Latina style icon Carmen Miranda. Another neighbor describes gay people as “dressed up in black leather. Zippers and chains all over...Dark glasses [and] chaps” (Willhoite, 1993). After having nightmares of men with sinister expressions in tropical-themed drag and leather, the children are overjoyed to discover that their uncle seems “normal.” Relative to depictions of other gay people in the book, Uncle Brett is normal because he is nonthreatening—he is white with short, straight, brown hair; he wears a plain, blue, collared shirt and brown dress pants; he carries a brown briefcase; and he enjoys and excels at activities appropriate for his gender, like catch. Although the book seems to have an affirming message about accepting queer people, it sends a clear message about which queer people are to be feared by children and which are nonthreatening. Nonthreatening queers are those who seem most like people mainstream western society considers normal: people who conform to expected gender roles, who have a vested interest parenting, and who are white and middle-upper class. These nonthreatening queers are by far the most represented in queer-themed literature for children. Based on a survey of 68 children’s books with queer characters, this paper argues that the representation of queer identities in children’s literature upholds more than challenges heteronormativity. I will first address ways many of the books perpetuate gender normativity by problematizing young male characters’ gender-transgressing behavior, portraying queer adults with less threatening gender presentations, and upholding gender binarism; next, I will address how the majority of the books promote repro-narrativity by focusing on monogamous couples’ strong desires and concerted efforts to have/raise children; I will then address race and class and the way white and upper-middle class queer characters are overrepresented while non-white and lower-class queer characters are underrepresented or not represented at all.
ContributorsLester, Jasmine (Author) / Danielson, Marivel (Thesis director) / Blasingame, James (Committee member) / Kuo, Karen (Committee member) / Barrett, The Honors College (Contributor) / College of Liberal Arts and Sciences (Contributor)
Created2012-12
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Description
Visual aides, such as PowerPoint slides, hand-outs, and lecture notes on whiteboards, are often used in classrooms to convey important content to learners, especially in high school and college. When using these visual learning aides, it is important to consider which qualities of these presentations can affect learning— positively or

Visual aides, such as PowerPoint slides, hand-outs, and lecture notes on whiteboards, are often used in classrooms to convey important content to learners, especially in high school and college. When using these visual learning aides, it is important to consider which qualities of these presentations can affect learning— positively or negatively—and how those qualities interact with individual student characteristics. In the present study, we examine the overlap between audio and text and how the effects of overlap potentially interact with reading comprehension abilities. The examination of these potential influences on learning in this study is inspired by Cognitive Load Theory, the Dual-Channel Assumption, and prior research.
ContributorsHarry, Danielle (Author) / McNamara, Danielle (Thesis director) / Presson, Clark (Committee member) / Jackson, Tanner (Committee member) / Roscoe, Rod (Committee member) / Barrett, The Honors College (Contributor) / College of Liberal Arts and Sciences (Contributor)
Created2012-12
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Description
Glioblastoma multiforme is associated with a very low survival rate and is recognized as the most vicious form of intracranial cancer. The Akt gene pathway has three different isoforms, each of which has a different role in the tumors of GBM. Preliminary data suggests that Akt3 may work to decrease

Glioblastoma multiforme is associated with a very low survival rate and is recognized as the most vicious form of intracranial cancer. The Akt gene pathway has three different isoforms, each of which has a different role in the tumors of GBM. Preliminary data suggests that Akt3 may work to decrease tumorigenicity. A produced image that visualizes the subcellular localization of Akt3 led the author to believe that Akt3 may reduce tumorigenicity by decreasing genomic instability caused by the cancer. To explore this, flow cytometry was performed on GBM cell lines with Akt3v1 over-expression, Akt3v2 over-expression, and a control glioma cell line.
ContributorsGhorayeb, Antoine (Author) / Neisewander, Janet (Thesis director) / Diehnelt, Chris (Committee member) / Moussallem, Suzan (Committee member) / Barrett, The Honors College (Contributor) / College of Liberal Arts and Sciences (Contributor)
Created2012-12