Matching Items (36)
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Extant evaluation studies of the Bayh-Dole Act of 1980 have focused primarily on its effects on the pace of innovation and on the norms and practices of academic research but neglected other public values. Seeking to redress this shortcoming, I begin by examining Bayh-Dole with respect to other relevant public

Extant evaluation studies of the Bayh-Dole Act of 1980 have focused primarily on its effects on the pace of innovation and on the norms and practices of academic research but neglected other public values. Seeking to redress this shortcoming, I begin by examining Bayh-Dole with respect to other relevant public values following the Public Value Failure approach. From that analysis, equity emerges as a pressing issue. I define equity issues, in a loosely Rawlsian sense, as situations of unfair distribution of political power and economic resources. My analysis identifies a business model of offices of technology transfer--that I call "nurturing start-ups"--that is likely to become a standard of practice. This model can foster either firm competition or concentration in emerging industries and will therefore have an impact on the distribution of economic benefits from innovation. In addition, political influence to reform Bayh-Dole is allocated disproportionately in favor of those who stand to gain from this policy. For instance, elite universities hold a larger share of the resources and voice of the university system. Consequently, adjusting the nurturing start-ups model to foster competition and increasing cooperation among universities should lead to a more equitable distribution of economic benefits and political voice in technology transfer. Conventional policy evaluation is also responsible for the neglect of equity considerations in Bayh-Dole studies. Currently, "what is the policy impact?" can be answered far more systematically than "why the impact matters?" or "is this policy designed and implemented legitimately?" The problem lies with the consequentialist theory of value that undergirds evaluation. Hence, I propose a deontological theory of evaluation to reaffirm the discipline's commitment to democratic policy making.
ContributorsValdivia, Walter (Author) / Guston, David H. (Thesis advisor) / Sarewitz, Daniel (Committee member) / Bozeman, Barry (Committee member) / Arizona State University (Publisher)
Created2011
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The three essays in this dissertation each examine how aspects of contemporary administrative structure within American research universities affect faculty outcomes. Specific aspects of administrative structure tested in this dissertation include the introduction of new administrative roles, administrative intensity (i.e. relative size of university administration), and competing roles between faculty,

The three essays in this dissertation each examine how aspects of contemporary administrative structure within American research universities affect faculty outcomes. Specific aspects of administrative structure tested in this dissertation include the introduction of new administrative roles, administrative intensity (i.e. relative size of university administration), and competing roles between faculty, administrators, and staff. Using quantitative statistical methods these aspects of administrative structure are tested for their effects on academic grant productivity, faculty job stress, and faculty job satisfaction. Administrative datasets and large scale national surveys make up the data for these studies and quantitative statistical methods confirm most of the hypothesized relationships.

In the first essay, findings from statistical modeling using instrumental variables suggest that academic researchers who receive administrative support for grant writing and management obtain fewer grants and have a lower success rate. However, the findings also suggest that the grants these researchers do receive are much larger in terms of dollars. The results indicate that administrative support is particularly beneficial in academic grant situations of high-risk, high-reward. In the second essay, ordered logit models reveal a statistically significant and stronger relationship between staff intensity (i.e., the ratio of faculty to staff workers) and faculty stress than the relationship between executive intensity (i.e., the ratio faculty to executive and managerial workers) and faculty job stress. These findings confirm theory that the work of faculty is more loosely coupled with the work of executives than it is with staff workers. A possible explanation is the increase in administrative work faculty must take on as there are fewer staff workers to take on administrative tasks. And finally, in the third essay results from multi-level modeling confirm that both role clarity and institutional support positively affect both a global measure of faculty job satisfaction and faculty satisfaction with how their work time is allocated. Understanding the effects that administrative structure has on faculty outcomes will aid universities as faculty administrative burdens ebb and flow in reaction to macro trends in higher education, such as unbundling of faculty roles, unbundling of services, neoliberalism, liberal arts decline, and administrative bloat.
ContributorsTaggart, Gabel (Author) / Welch, Eric (Thesis advisor) / Bozeman, Barry (Committee member) / Ott, Molly (Committee member) / Stritch, Justin (Committee member) / Arizona State University (Publisher)
Created2017
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The amount of time and effort that university researchers spend writing grants and executing grant administration responsibilities is one of the biggest challenges for science policy. This study aims to explore the complexity of the phenomenon of burdens in the administrative procedure for principal investigators (PIs) in sponsored research. The

The amount of time and effort that university researchers spend writing grants and executing grant administration responsibilities is one of the biggest challenges for science policy. This study aims to explore the complexity of the phenomenon of burdens in the administrative procedure for principal investigators (PIs) in sponsored research. The findings make a theoretical contribution to the study of burdens and red tape by closely examining the processes in which the burdens emerge, increase, and decrease; in doing so, this research will lay the groundwork for future studies of burdens and sponsored research systems. This study assumes that burdens are embedded in the social process, not merely in the number of required documentation or time spent on the procedure. The two overarching research questions are as follows: (1) What do researchers perceive or experience as a burden in grant proposal preparation and submission in sponsored research? (2) What are the possible factors or hypotheses to explain the generation, increase, and decrease of burdens? This single case study of a large research university examines the burdens faced by university researchers as they prepare and submit grant proposals. Primary data comes from semi-structured interviews with thirty-one PIs in science and engineering schools, and four interviews with research administration staff. Based on the interview data and theoretical arguments, this study illustrates the burdens in two categories: Burdens related to the proposal system, rules, and requirements; and burdens PIs experience with pre-award staff and relations. In addition, this study assesses each PI’s burden level in terms of the number of tasks in the proposal process, and the quality of the pre-award staff and services the PI experiences. This study further examines possible contributing factors and tentative hypotheses of burdens. In the discussion, this study develops theoretical arguments about the nature and consequences of burdens and fundamental issues in the grant system, and discuss prescriptions for PIs, universities, and sponsored research systems.
ContributorsFukumoto, Eriko (Author) / Bozeman, Barry (Thesis advisor) / Welch, Eric (Committee member) / Anderson, Derrick M (Committee member) / Arizona State University (Publisher)
Created2018
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Each of the three essays in this dissertation examine an aspect of health or health care in society. Areas explored within this dissertation include health care as a public value, proscriptive genomic policies, and socio-technical futures of the human lifespan. The first essay explores different forms of health care systems

Each of the three essays in this dissertation examine an aspect of health or health care in society. Areas explored within this dissertation include health care as a public value, proscriptive genomic policies, and socio-technical futures of the human lifespan. The first essay explores different forms of health care systems and attempts to understand who believes access to health care is a public value. Using a survey of more than 2,000 U.S. citizens, this study presents statistically significant empirical evidence regarding values and other attributes that predict the probability of individuals within age-based cohorts identifying access to health care as a public value. In the second essay, a menu of policy recommendations for federal regulators is proposed in order to address the lack of uniformity in current state laws concerning genetic information. The policy recommendations consider genetic information as property, privacy protections for re-identifying de-identified genomic information, the establishment of guidelines for law enforcement agencies to access nonforensic databases in criminal investigations, and anti-piracy protections for individuals and their genetic information. The third and final essay explores the socio-technical artifacts of the current health care system for documenting both life and death to understand the potential for altering the future of insurance, the health care delivery system, and individual health outcomes. Through the development of a complex scenario, this essay explores the long-term socio-technical futures of implementing a technology that continuously collects and stores genetic, environmental, and social information from life to death of individual participants.
ContributorsWade, Nathaniel Lane (Author) / Bozeman, Barry (Thesis advisor) / Sarewitz, Daniel (Committee member) / Cook-Deegan, Robert (Committee member) / Arizona State University (Publisher)
Created2019
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The purpose of this study was to create a screening tool specifically for the identification of sex trafficking victims in the medical setting through the analysis of existing human trafficking screening tool studies geared towards use in the medical setting. Screening questions from these studies were compiled and modified into

The purpose of this study was to create a screening tool specifically for the identification of sex trafficking victims in the medical setting through the analysis of existing human trafficking screening tool studies geared towards use in the medical setting. Screening questions from these studies were compiled and modified into a survey that was distributed to healthcare professionals through the nationwide HEAL (Health Professional Education, Advocacy, Linkage) Trafficking listserv. Each screening tool study demonstrated benefits and disadvantages that were helpful in the sampling and selection of screening tool questions. The small sample size and a lack of data on the attitudes of medical professionals on sex trafficked victims were noted as limitations to this study. Further implications for this study would include validating the screening tool questions in a medical setting to determine the sensitivity of the survey in identifying patients as possible sex trafficking victims.
ContributorsCatano, Karen Samantha (Co-author) / Byun, Jiwon (Co-author) / Roe-Sepowitz, Dominique (Thesis director) / Lee, Maurice (Committee member) / School for the Science of Health Care Delivery (Contributor) / College of Integrative Sciences and Arts (Contributor) / W.P. Carey School of Business (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
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The term "Children with Special Health Care Needs," often abbreviated as CSHCN, is an umbrella term, encompassing a wide variety of children with a range of health conditions. As of 2011, CSHCN constituted 15-20% of all children age 0-17 in the United States (Bethell et al., 2013). Despite this, CSHCN

The term "Children with Special Health Care Needs," often abbreviated as CSHCN, is an umbrella term, encompassing a wide variety of children with a range of health conditions. As of 2011, CSHCN constituted 15-20% of all children age 0-17 in the United States (Bethell et al., 2013). Despite this, CSHCN "account for 80% of all pediatric medical expenses." (Hardy, Vivier, Rivara, & Melzer, 2012). This project specifically compares children with physical disability and behavioral disability in hopes of gaining a greater insight into both groups, assessing/comparing differences, and evaluating whether or not having a co-morbidity has a mediating or contending effect on care coordination.
ContributorsDevineni, Asha (Author) / McCullough, Mac (Thesis director) / Reddy, Swapna (Committee member) / School for the Science of Health Care Delivery (Contributor) / Barrett, The Honors College (Contributor)
Created2017-12
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The Paradise Valley Family Resource Center (PVFRC) is a not for profit, community based organization funded by First Things First and a part of the Paradise Valley Unified School District (PVUSD) in Phoenix, Arizona. The mission of this organization is to connect and strengthen families with children from birth to

The Paradise Valley Family Resource Center (PVFRC) is a not for profit, community based organization funded by First Things First and a part of the Paradise Valley Unified School District (PVUSD) in Phoenix, Arizona. The mission of this organization is to connect and strengthen families with children from birth to five years old in the Phoenix valley. The PVFRC longed to be more cognizant of what the needs of the community they serve are, and how they, as an organization, can administer programs of value to the community. Hence, the PVFRC entered a partnership with the Community Action Research Experiences (CARE) program at Arizona State University to develop a research proposal to improve their effectiveness and efficiency at achieving their mission. The purpose of this research project was to identify and evaluate the needs of the families with children ages birth to five within the community, to improve upon existing programs and services or to implement new programs, and to discover more effective modes of awareness and advertisement to the community about the programs and services the PVFRC provides. The main research questions of the experiment included asking participants about what programs and services they need, wish, or want to exist at the PVFRC, what barriers or gaps they see or experience regarding attending the PVFRC, how did participants learn about the PVFRC, and what are the best ways to contact families in their community. The methods of the research included conducting focus group interviews with families who utilize the programs and services at the PVFRC and with early childhood professionals in the Paradise Valley Unified School District (PVUSD), which included social workers and preschool teachers. A total of 25 participants were interviewed (10 families, 6 social workers, and 9 preschool teachers) and responses from the interviews were coded by the researcher. The results of the research was that the PVFRC is meeting many needs and current families are satisfied, participants desire some changes to current programs and services, and the best modes of advertisement and awareness were "word of mouth" and the internet. It was recommended that in order to better achieve their mission, it is advised that the PVFRC make appropriate changes to programs and services as suggested by the participants, connect with mom's or parents groups in the community, collaborate with preschool teachers on the front line, and increase their online presence through the use of social media and their website.
ContributorsHoran, Mary Jensen (Author) / Foster, Stacie (Thesis director) / Brougham, Jennifer (Committee member) / Dumka, Larry (Committee member) / T. Denny Sanford School of Social and Family Dynamics (Contributor) / School of Molecular Sciences (Contributor) / School for the Science of Health Care Delivery (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
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Breast and other solid tumors exhibit high and varying degrees of intra-tumor heterogeneity resulting in targeted therapy resistance and other challenges that make the management and treatment of these diseases rather difficult. Due to the presence of admixtures of non-neoplastic cells with polyclonal cell populations, it is difficult to define

Breast and other solid tumors exhibit high and varying degrees of intra-tumor heterogeneity resulting in targeted therapy resistance and other challenges that make the management and treatment of these diseases rather difficult. Due to the presence of admixtures of non-neoplastic cells with polyclonal cell populations, it is difficult to define cancer genomes in patient samples. By isolating tumor cells from normal cells, and enriching distinct clonal populations, clinically relevant genomic aberrations that drive disease can be identified in patients in vivo. An in-depth analysis of clonal architecture and tumor heterogeneity was performed in a stage II chemoradiation-naïve breast cancer from a sixty-five year old patient. DAPI-based DNA content measurements and DNA content-based flow sorting was used to to isolate nuclei from distinct clonal populations of diploid and aneuploid tumor cells in surgical tumor samples. We combined DNA content-based flow cytometry and ploidy analysis with high-definition array comparative genomic hybridization (aCGH) and next-generation sequencing technologies to interrogate the genomes of multiple biopsies from the breast cancer. The detailed profiles of ploidy, copy number aberrations and mutations were used to recreate and map the lineages present within the tumor. The clonal analysis revealed driver events for tumor progression (a heterozygous germline BRCA2 mutation converted to homozygosity within the tumor by a copy number event and the constitutive activation of Notch and Akt signaling pathways. The highlighted approach has broad implications in the study of tumor heterogeneity by providing a unique ultra-high resolution of polyclonal tumors that can advance effective therapies and clinical management of patients with this disease.
ContributorsLaughlin, Brady Scott (Author) / Ankeny, Casey (Thesis director) / Barrett, Michael (Committee member) / Barrett, The Honors College (Contributor) / Harrington Bioengineering Program (Contributor) / School for the Science of Health Care Delivery (Contributor)
Created2015-05
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Considering the overwhelming prevalence of BPH, how can it best be managed in light of the aging population? The purpose of this investigation is to illustrate that BPH and LUTS are conditions that are highly conducive to health literacy technology interventions. This objective will be met by: a) Providing an

Considering the overwhelming prevalence of BPH, how can it best be managed in light of the aging population? The purpose of this investigation is to illustrate that BPH and LUTS are conditions that are highly conducive to health literacy technology interventions. This objective will be met by: a) Providing an overview of the clinically relevant information regarding BPH, including anatomy, physiology, epidemiology, symptoms, and medical treatment for the disease; b) Establishing the necessity for novel health care delivery solutions by identifying past successes and challenges associated with technologic advances in related fields; c) Providing evidence of a lack of a systematic approach to BPH education, especially as it relates to health literacy. The relative successes and failures of previously established clinical decision aids will be discussed, leading to recommendations on how to improve upon these standards. Finally, the procedures and results of a pilot study will be analyzed in an effort to further highlight the necessity of engaging patients in the clinical decision making process.
Created2014-12
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Ruptures in the anterior cruciate ligament are a prevalent injury, particularly in young athletes. This injury is frequently treated with surgical repair utilizing autologous tissue, cadaver allografts or synthetic grafts. However there is no definitive answer on which is the best graft option. This review aims to compare clinical results

Ruptures in the anterior cruciate ligament are a prevalent injury, particularly in young athletes. This injury is frequently treated with surgical repair utilizing autologous tissue, cadaver allografts or synthetic grafts. However there is no definitive answer on which is the best graft option. This review aims to compare clinical results of patellar tendon autograft (PT), hamstring autograft (HT), cadaver allograft and LARS synthetic ligament in ACL reconstruction. The ASU library was systematically searched for comparison studies or meta-analyses that compared or described ACL reconstruction graft options. The results of the studies were analyzed according to re-tear rate, return to pre-injury level of activity, KT-1000 laxity scores, post-operative muscle strength, International Knee Documentation Committee Score (IKDC), Lysholm score, Lachman test and donor site morbidity. Allografts showed the highest re-tear rate and increase in laxity when compared with the PT autograft and HT autograft. PT autograft provided the most stability according to the KT-1000 results. Knee extensor muscle strength was not graft dependent, but knee flexor strength decreased significantly in HT autograft patients. All grafts showed comparable results for IKDC, Lysholm scores and Lachman tests. There was increased anterior knee pain in PT autograft patients however this did not seem to have an affect on the stability or durability of the graft. The PT autograft is the best choice for individuals undergoing ACL reconstruction on the basis of lower re-tear rates and greater joint stability.
ContributorsNormen, Eliza Armstrong (Author) / Broman, Tannah (Thesis director) / Harper, Erin (Committee member) / Barrett, The Honors College (Contributor) / School of Nutrition and Health Promotion (Contributor) / School for the Science of Health Care Delivery (Contributor)
Created2015-05