Matching Items (49)
Description
The power of science lies in its ability to infer and predict the
existence of objects from which no direct information can be obtained
experimentally or observationally. A well known example is to
ascertain the existence of black holes of various masses in different
parts of the universe from indirect evidence, such as X-ray emissions.
In the field of complex networks, the problem of detecting
hidden nodes can be stated, as follows. Consider a network whose
topology is completely unknown but whose nodes consist of two types:
one accessible and another inaccessible from the outside world. The
accessible nodes can be observed or monitored, and it is assumed that time
series are available from each node in this group. The inaccessible
nodes are shielded from the outside and they are essentially
``hidden.'' The question is, based solely on the
available time series from the accessible nodes, can the existence and
locations of the hidden nodes be inferred? A completely data-driven,
compressive-sensing based method is developed to address this issue by utilizing
complex weighted networks of nonlinear oscillators, evolutionary game
and geospatial networks.
Both microbes and multicellular organisms actively regulate their cell
fate determination to cope with changing environments or to ensure
proper development. Here, the synthetic biology approaches are used to
engineer bistable gene networks to demonstrate that stochastic and
permanent cell fate determination can be achieved through initializing
gene regulatory networks (GRNs) at the boundary between dynamic
attractors. This is experimentally realized by linking a synthetic GRN
to a natural output of galactose metabolism regulation in yeast.
Combining mathematical modeling and flow cytometry, the
engineered systems are shown to be bistable and that inherent gene expression
stochasticity does not induce spontaneous state transitioning at
steady state. By interfacing rationally designed synthetic
GRNs with background gene regulation mechanisms, this work
investigates intricate properties of networks that illuminate possible
regulatory mechanisms for cell differentiation and development that
can be initiated from points of instability.
existence of objects from which no direct information can be obtained
experimentally or observationally. A well known example is to
ascertain the existence of black holes of various masses in different
parts of the universe from indirect evidence, such as X-ray emissions.
In the field of complex networks, the problem of detecting
hidden nodes can be stated, as follows. Consider a network whose
topology is completely unknown but whose nodes consist of two types:
one accessible and another inaccessible from the outside world. The
accessible nodes can be observed or monitored, and it is assumed that time
series are available from each node in this group. The inaccessible
nodes are shielded from the outside and they are essentially
``hidden.'' The question is, based solely on the
available time series from the accessible nodes, can the existence and
locations of the hidden nodes be inferred? A completely data-driven,
compressive-sensing based method is developed to address this issue by utilizing
complex weighted networks of nonlinear oscillators, evolutionary game
and geospatial networks.
Both microbes and multicellular organisms actively regulate their cell
fate determination to cope with changing environments or to ensure
proper development. Here, the synthetic biology approaches are used to
engineer bistable gene networks to demonstrate that stochastic and
permanent cell fate determination can be achieved through initializing
gene regulatory networks (GRNs) at the boundary between dynamic
attractors. This is experimentally realized by linking a synthetic GRN
to a natural output of galactose metabolism regulation in yeast.
Combining mathematical modeling and flow cytometry, the
engineered systems are shown to be bistable and that inherent gene expression
stochasticity does not induce spontaneous state transitioning at
steady state. By interfacing rationally designed synthetic
GRNs with background gene regulation mechanisms, this work
investigates intricate properties of networks that illuminate possible
regulatory mechanisms for cell differentiation and development that
can be initiated from points of instability.
ContributorsSu, Ri-Qi (Author) / Lai, Ying-Cheng (Thesis advisor) / Wang, Xiao (Thesis advisor) / Bliss, Daniel (Committee member) / Tepedelenlioğlu, Cihan (Committee member) / Arizona State University (Publisher)
Created2015
Description
The quality of real-world visual content is typically impaired by many factors including image noise and blur. Detecting and analyzing these impairments are important steps for multiple computer vision tasks. This work focuses on perceptual-based locally adaptive noise and blur detection and their application to image restoration.
In the context of noise detection, this work proposes perceptual-based full-reference and no-reference objective image quality metrics by integrating perceptually weighted local noise into a probability summation model. Results are reported on both the LIVE and TID2008 databases. The proposed metrics achieve consistently a good performance across noise types and across databases as compared to many of the best very recent quality metrics. The proposed metrics are able to predict with high accuracy the relative amount of perceived noise in images of different content.
In the context of blur detection, existing approaches are either computationally costly or cannot perform reliably when dealing with the spatially-varying nature of the defocus blur. In addition, many existing approaches do not take human perception into account. This work proposes a blur detection algorithm that is capable of detecting and quantifying the level of spatially-varying blur by integrating directional edge spread calculation, probability of blur detection and local probability summation. The proposed method generates a blur map indicating the relative amount of perceived local blurriness. In order to detect the flat
ear flat regions that do not contribute to perceivable blur, a perceptual model based on the Just Noticeable Difference (JND) is further integrated in the proposed blur detection algorithm to generate perceptually significant blur maps. We compare our proposed method with six other state-of-the-art blur detection methods. Experimental results show that the proposed method performs the best both visually and quantitatively.
This work further investigates the application of the proposed blur detection methods to image deblurring. Two selective perceptual-based image deblurring frameworks are proposed, to improve the image deblurring results and to reduce the restoration artifacts. In addition, an edge-enhanced super resolution algorithm is proposed, and is shown to achieve better reconstructed results for the edge regions.
In the context of noise detection, this work proposes perceptual-based full-reference and no-reference objective image quality metrics by integrating perceptually weighted local noise into a probability summation model. Results are reported on both the LIVE and TID2008 databases. The proposed metrics achieve consistently a good performance across noise types and across databases as compared to many of the best very recent quality metrics. The proposed metrics are able to predict with high accuracy the relative amount of perceived noise in images of different content.
In the context of blur detection, existing approaches are either computationally costly or cannot perform reliably when dealing with the spatially-varying nature of the defocus blur. In addition, many existing approaches do not take human perception into account. This work proposes a blur detection algorithm that is capable of detecting and quantifying the level of spatially-varying blur by integrating directional edge spread calculation, probability of blur detection and local probability summation. The proposed method generates a blur map indicating the relative amount of perceived local blurriness. In order to detect the flat
ear flat regions that do not contribute to perceivable blur, a perceptual model based on the Just Noticeable Difference (JND) is further integrated in the proposed blur detection algorithm to generate perceptually significant blur maps. We compare our proposed method with six other state-of-the-art blur detection methods. Experimental results show that the proposed method performs the best both visually and quantitatively.
This work further investigates the application of the proposed blur detection methods to image deblurring. Two selective perceptual-based image deblurring frameworks are proposed, to improve the image deblurring results and to reduce the restoration artifacts. In addition, an edge-enhanced super resolution algorithm is proposed, and is shown to achieve better reconstructed results for the edge regions.
ContributorsZhu, Tong (Author) / Karam, Lina (Thesis advisor) / Li, Baoxin (Committee member) / Bliss, Daniel (Committee member) / Myint, Soe (Committee member) / Arizona State University (Publisher)
Created2016
Description
Eigenvalues of the Gram matrix formed from received data frequently appear in sufficient detection statistics for multi-channel detection with Generalized Likelihood Ratio (GLRT) and Bayesian tests. In a frequently presented model for passive radar, in which the null hypothesis is that the channels are independent and contain only complex white Gaussian noise and the alternative hypothesis is that the channels contain a common rank-one signal in the mean, the GLRT statistic is the largest eigenvalue $\lambda_1$ of the Gram matrix formed from data. This Gram matrix has a Wishart distribution. Although exact expressions for the distribution of $\lambda_1$ are known under both hypotheses, numerically calculating values of these distribution functions presents difficulties in cases where the dimension of the data vectors is large. This dissertation presents tractable methods for computing the distribution of $\lambda_1$ under both the null and alternative hypotheses through a technique of expanding known expressions for the distribution of $\lambda_1$ as inner products of orthogonal polynomials. These newly presented expressions for the distribution allow for computation of detection thresholds and receiver operating characteristic curves to arbitrary precision in floating point arithmetic. This represents a significant advancement over the state of the art in a problem that could previously only be addressed by Monte Carlo methods.
ContributorsJones, Scott, Ph.D (Author) / Cochran, Douglas (Thesis advisor) / Berisha, Visar (Committee member) / Bliss, Daniel (Committee member) / Kosut, Oliver (Committee member) / Richmond, Christ (Committee member) / Arizona State University (Publisher)
Created2019
Description
The open nature of the wireless communication medium makes it inherently vulnerable to an active attack, wherein a malicious adversary (or jammer) transmits into the medium to disrupt the operation of the legitimate users. Therefore, developing techniques to manage the presence of a jammer and to characterize the effect of an attacker on the fundamental limits of wireless communication networks is important. This dissertation studies various Gaussian communication networks in the presence of such an adversarial jammer.
First of all, a standard Gaussian channel is considered in the presence of a jammer, known as a Gaussian arbitrarily-varying channel, but with list-decoding at the receiver. The receiver decodes a list of messages, instead of only one message, with the goal of the correct message being an element of the list. The capacity is characterized, and it is shown that under some transmitter's power constraints the adversary is able to suspend the communication between the legitimate users and make the capacity zero.
Next, generalized packing lemmas are introduced for Gaussian adversarial channels to achieve the capacity bounds for three Gaussian multi-user channels in the presence of adversarial jammers. Inner and outer bounds on the capacity regions of Gaussian multiple-access channels, Gaussian broadcast channels, and Gaussian interference channels are derived in the presence of malicious jammers. For the Gaussian multiple-access channels with jammer, the capacity bounds coincide. In this dissertation, the adversaries can send any arbitrary signals to the channel while none of the transmitter and the receiver knows the adversarial signals' distribution.
Finally, the capacity of the standard point-to-point Gaussian fading channel in the presence of one jammer is investigated under multiple scenarios of channel state information availability, which is the knowledge of exact fading coefficients. The channel state information is always partially or fully known at the receiver to decode the message while the transmitter or the adversary may or may not have access to this information. Here, the adversary model is the same as the previous cases with no knowledge about the user's transmitted signal except possibly the knowledge of the fading path.
First of all, a standard Gaussian channel is considered in the presence of a jammer, known as a Gaussian arbitrarily-varying channel, but with list-decoding at the receiver. The receiver decodes a list of messages, instead of only one message, with the goal of the correct message being an element of the list. The capacity is characterized, and it is shown that under some transmitter's power constraints the adversary is able to suspend the communication between the legitimate users and make the capacity zero.
Next, generalized packing lemmas are introduced for Gaussian adversarial channels to achieve the capacity bounds for three Gaussian multi-user channels in the presence of adversarial jammers. Inner and outer bounds on the capacity regions of Gaussian multiple-access channels, Gaussian broadcast channels, and Gaussian interference channels are derived in the presence of malicious jammers. For the Gaussian multiple-access channels with jammer, the capacity bounds coincide. In this dissertation, the adversaries can send any arbitrary signals to the channel while none of the transmitter and the receiver knows the adversarial signals' distribution.
Finally, the capacity of the standard point-to-point Gaussian fading channel in the presence of one jammer is investigated under multiple scenarios of channel state information availability, which is the knowledge of exact fading coefficients. The channel state information is always partially or fully known at the receiver to decode the message while the transmitter or the adversary may or may not have access to this information. Here, the adversary model is the same as the previous cases with no knowledge about the user's transmitted signal except possibly the knowledge of the fading path.
ContributorsHosseinigoki, Fatemeh (Author) / Kosut, Oliver (Thesis advisor) / Zhang, Junshan (Committee member) / Sankar, Lalitha (Committee member) / Bliss, Daniel (Committee member) / Arizona State University (Publisher)
Created2019
Machine Learning-based Analysis of the Relationship Between the Human Gut Microbiome and Bone Health
Description
The Human Gut Microbiome (GM) modulates a variety of structural, metabolic, and protective functions to benefit the host. A few recent studies also support the role of the gut microbiome in the regulation of bone health. The relationship between GM and bone health was analyzed based on the data collected from a group of twenty-three adolescent boys and girls who participated in a controlled feeding study, during which two different doses (0 g/d fiber and 12 g/d fiber) of Soluble Corn Fiber (SCF) were added to their diet. This analysis was performed by predicting measures of Bone Mineral Density (BMD) and Bone Mineral Content (BMC) which are indicators of bone strength, using the GM sequence of proportions of 178 microbes collected from 23 subjects, by building a machine learning regression model. The model developed was evaluated by calculating performance metrics such as Root Mean Squared Error, Pearson’s correlation coefficient, and Spearman’s rank correlation coefficient, using cross-validation. A noticeable correlation was observed between the GM and bone health, and it was observed that the overall prediction correlation was higher with SCF intervention (r ~ 0.51). The genera of microbes that played an important role in this relationship were identified. Eubacterium (g), Bacteroides (g), Megamonas (g), Acetivibrio (g), Faecalibacterium (g), and Paraprevotella (g) were some of the microbes that showed an increase in proportion with SCF intervention.
ContributorsKetha Hazarath, Pravallika Reddy (Author) / Bliss, Daniel (Thesis advisor) / Whisner, Corrie (Committee member) / Dasarathy, Gautam (Committee member) / Arizona State University (Publisher)
Created2020
Description
QR decomposition (QRD) of a matrix is one of the most common linear algebra operationsused for the decomposition of a square
on-square matrix. It has a wide range
of applications especially in Multiple Input-Multiple Output (MIMO) communication
systems. Unfortunately it has high computation complexity { for matrix size of nxn,
QRD has O(n3) complexity and back substitution, which is used to solve a system
of linear equations, has O(n2) complexity. Thus, as the matrix size increases, the
hardware resource requirement for QRD and back substitution increases signicantly.
This thesis presents the design and implementation of a
exible QRD and back substitution accelerator using a folded architecture. It can support matrix sizes of
4x4, 8x8, 12x12, 16x16, and 20x20 with low hardware resource requirement.
The proposed architecture is based on the systolic array implementation of the
Givens algorithm for QRD. It is built with three dierent types of computation blocks
which are connected in a 2-D array structure. These blocks are controlled by a
scheduler which facilitates reusability of the blocks to perform computation for any
input matrix size which is a multiple of 4. These blocks are designed using two
basic programming elements which support both the forward and backward paths to
compute matrix R in QRD and column-matrix X in back substitution computation.
The proposed architecture has been mapped to Xilinx Zynq Ultrascale+ FPGA
(Field Programmable Gate Array), ZCU102. All inputs are complex with precision
of 40 bits (38 fractional bits and 1 signed bit). The architecture can be clocked at
50 MHz. The synthesis results of the folded architecture for dierent matrix sizes
are presented. The results show that the folded architecture can support QRD and
back substitution for inputs of large sizes which otherwise cannot t on an FPGA
when implemented using a
at architecture. The memory sizes required for dierent
matrix sizes are also presented.
on-square matrix. It has a wide range
of applications especially in Multiple Input-Multiple Output (MIMO) communication
systems. Unfortunately it has high computation complexity { for matrix size of nxn,
QRD has O(n3) complexity and back substitution, which is used to solve a system
of linear equations, has O(n2) complexity. Thus, as the matrix size increases, the
hardware resource requirement for QRD and back substitution increases signicantly.
This thesis presents the design and implementation of a
exible QRD and back substitution accelerator using a folded architecture. It can support matrix sizes of
4x4, 8x8, 12x12, 16x16, and 20x20 with low hardware resource requirement.
The proposed architecture is based on the systolic array implementation of the
Givens algorithm for QRD. It is built with three dierent types of computation blocks
which are connected in a 2-D array structure. These blocks are controlled by a
scheduler which facilitates reusability of the blocks to perform computation for any
input matrix size which is a multiple of 4. These blocks are designed using two
basic programming elements which support both the forward and backward paths to
compute matrix R in QRD and column-matrix X in back substitution computation.
The proposed architecture has been mapped to Xilinx Zynq Ultrascale+ FPGA
(Field Programmable Gate Array), ZCU102. All inputs are complex with precision
of 40 bits (38 fractional bits and 1 signed bit). The architecture can be clocked at
50 MHz. The synthesis results of the folded architecture for dierent matrix sizes
are presented. The results show that the folded architecture can support QRD and
back substitution for inputs of large sizes which otherwise cannot t on an FPGA
when implemented using a
at architecture. The memory sizes required for dierent
matrix sizes are also presented.
ContributorsKanagala, Srimayee (Author) / Chakrabarti, Chaitali (Thesis advisor) / Bliss, Daniel (Committee member) / Cao, Yu (Kevin) (Committee member) / Arizona State University (Publisher)
Created2020
Description
Lattice-based Cryptography is an up and coming field of cryptography that utilizes the difficulty of lattice problems to design lattice-based cryptosystems that are resistant to quantum attacks and applicable to Fully Homomorphic Encryption schemes (FHE). In this thesis, the parallelization of the Residue Number System (RNS) and algorithmic efficiency of the Number Theoretic Transform (NTT) are combined to tackle the most significant bottleneck of polynomial ring multiplication with the hardware design of an optimized RNS-based NTT polynomial multiplier. The design utilizes Negative Wrapped Convolution, the NTT, RNS Montgomery reduction with Bajard and Shenoy extensions, and optimized modular 32-bit channel arithmetic for nine RNS channels to accomplish an RNS polynomial multiplication. In addition to a full software implementation of the whole system, a pipelined and optimized RNS-based NTT unit with 4 RNS butterflies is implemented on the Xilinx Artix-7 FPGA(xc7a200tlffg1156-2L) for size and delay estimates. The hardware implementation achieves an operating frequency of 47.043 MHz and utilizes 13239 LUT's, 4010 FF's, and 330 DSP blocks, allowing for multiple simultaneously operating NTT units depending on FGPA size constraints.
ContributorsBrist, Logan Alan (Author) / Chakrabarti, Chaitali (Thesis advisor) / Papandreou-Suppappola, Antonia (Committee member) / Bliss, Daniel (Committee member) / Arizona State University (Publisher)
Created2020
Description
The inverse problem in electroencephalography (EEG) is the determination of form and location of neural activity associated to EEG recordings. This determination is of interest in evoked potential experiments where the activity is elicited by an external stimulus. This work investigates three aspects of this problem: the use of forward methods in its solution, the elimination of artifacts that complicate the accurate determination of sources, and the construction of physical models that capture the electrical properties of the human head.
Results from this work aim to increase the accuracy and performance of the inverse solution process.
The inverse problem can be approached by constructing forward solutions where, for a know source, the scalp potentials are determined. This work demonstrates that the use of two variables, the dissipated power and the accumulated charge at interfaces, leads to a new solution method for the forward problem. The accumulated charge satisfies a boundary integral equation. Consideration of dissipated power determines bounds on the range of eigenvalues of the integral operators that appear in this formulation. The new method uses the eigenvalue structure to regularize singular integral operators thus allowing unambiguous solutions to the forward problem.
A major problem in the estimation of properties of neural sources is the presence of artifacts that corrupt EEG recordings. A method is proposed for the determination of inverse solutions that integrates sequential Bayesian estimation with probabilistic data association in order to suppress artifacts before estimating neural activity. This method improves the tracking of neural activity in a dynamic setting in the presence of artifacts.
Solution of the inverse problem requires the use of models of the human head. The electrical properties of biological tissues are best described by frequency dependent complex conductivities. Head models in EEG analysis, however, usually consider head regions as having only constant real conductivities. This work presents a model for tissues as composed of confined electrolytes that predicts complex conductivities for macroscopic measurements. These results indicate ways in which EEG models can be improved.
Results from this work aim to increase the accuracy and performance of the inverse solution process.
The inverse problem can be approached by constructing forward solutions where, for a know source, the scalp potentials are determined. This work demonstrates that the use of two variables, the dissipated power and the accumulated charge at interfaces, leads to a new solution method for the forward problem. The accumulated charge satisfies a boundary integral equation. Consideration of dissipated power determines bounds on the range of eigenvalues of the integral operators that appear in this formulation. The new method uses the eigenvalue structure to regularize singular integral operators thus allowing unambiguous solutions to the forward problem.
A major problem in the estimation of properties of neural sources is the presence of artifacts that corrupt EEG recordings. A method is proposed for the determination of inverse solutions that integrates sequential Bayesian estimation with probabilistic data association in order to suppress artifacts before estimating neural activity. This method improves the tracking of neural activity in a dynamic setting in the presence of artifacts.
Solution of the inverse problem requires the use of models of the human head. The electrical properties of biological tissues are best described by frequency dependent complex conductivities. Head models in EEG analysis, however, usually consider head regions as having only constant real conductivities. This work presents a model for tissues as composed of confined electrolytes that predicts complex conductivities for macroscopic measurements. These results indicate ways in which EEG models can be improved.
ContributorsSolis, Francisco Jr. (Author) / Papandreou-Suppappola, Antonia (Thesis advisor) / Berisha, Visar (Committee member) / Bliss, Daniel (Committee member) / Moraffah, Bahman (Committee member) / Arizona State University (Publisher)
Created2020
Description
The following document describes the hardware implementation and analysis of Temporal Interference Mitigation using High-Level Synthesis. As the problem of spectral congestion becomes more chronic and widespread, Electromagnetic radio frequency (RF) based systems are posing as viable solution to this problem. Among the existing RF methods Cooperation based systems have been a solution to a host of congestion problems. One of the most important elements of RF receiver is the spatially adaptive part of the receiver. Temporal Mitigation is vital technique employed at the receiver for signal recovery and future propagation along the radar chain.
The computationally intensive parts of temporal mitigation are identified and hardware accelerated. The hardware implementation is based on sequential approach with optimizations applied on the individual components for better performance.
An extensive analysis using a range of fixed point data types is performed to find the optimal data type necessary.
Finally a hybrid combination of data types for different components of temporal mitigation is proposed based on results from the above analysis.
The computationally intensive parts of temporal mitigation are identified and hardware accelerated. The hardware implementation is based on sequential approach with optimizations applied on the individual components for better performance.
An extensive analysis using a range of fixed point data types is performed to find the optimal data type necessary.
Finally a hybrid combination of data types for different components of temporal mitigation is proposed based on results from the above analysis.
ContributorsSiddiqui, Saquib Ahmad (Author) / Bliss, Daniel (Thesis advisor) / Chakrabarti, Chaitali (Committee member) / Ogras, Umit Y. (Committee member) / Jayasuriya, Suren (Committee member) / Arizona State University (Publisher)
Created2020