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- Creators: Barrett, The Honors College
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Description
Carbon allotropes are the basis for many exciting advancements in technology. While sp² and sp³ hybridizations are well understood, the sp¹ hybridized carbon has been elusive. However, with recent advances made using a pulsed laser ablation in liquid technique, sp¹ hybridized carbon allotropes have been created. The fabricated carbon chain is composed of sp¹ and sp³ hybridized bonds, but it also incorporates nanoparticles such as gold or possibly silver to stabilize the chain. The polyyne generated in this process is called pseudocarbyne due to its striking resemblance to the theoretical carbyne. The formation of these carbon chains is yet to be fully understood, but significant progress has been made in determining the temperature of the plasma in which the pseudocarbyne is formed. When a 532 nm pulsed laser with a pulsed energy of 250 mJ and pulse length of 10ns is used to ablate a gold target, a peak temperature of 13400 K is measured. When measured using Laser-Induced Breakdown spectroscopy (LIBS) the average temperature of the neutral carbon plasma over one second was 4590±172 K. This temperature strongly suggests that the current theoretical model used to describe the temperature at which pseudocarbyne generates is accurate.
ContributorsWala, Ryland Gerald (Co-author) / Wala, Ryland (Co-author) / Sayres, Scott (Thesis director) / Steimle, Timothy (Committee member) / Drucker, Jeffery (Committee member) / Historical, Philosophical & Religious Studies (Contributor) / Dean, W.P. Carey School of Business (Contributor) / Department of Physics (Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
This thesis seeks to examine shortcomings in space law by focusing on two interconnected aspects: privatization and space debris. The aspects of privatization and space debris will be examined under the context of the Outer Space Treaty (OST) and other relevant legal instruments. Privatization and space debris are two current challenges that the OST fails to regulate efficiently. While the OST was being drafted, the international community did not foresee problems such as privatization and space debris. This is significant because we are witnessing an increase in privatization of space activities and corporations as well as a massive accumulation of dangerous space debris. While the OST grants states the power to regulate private space companies and the accretion of space debris, national laws rarely align with the OST, leading to the abuse of international space laws. We will make recommendations at the end of the thesis in an effort to revise the use of soft language in the OST to attune national laws with international laws as well as address the growing ambiguity surrounding privatization and space debris.
ContributorsSimper, Elizabeth Mary (Co-author) / Simper, Elizabeth (Co-author) / Ziglin, Kathryn (Co-author) / Iheduru, Okechukwu (Thesis director) / Foy, Joseph (Committee member) / School of Politics and Global Studies (Contributor, Contributor, Contributor) / School of Human Evolution & Social Change (Contributor) / Department of Management and Entrepreneurship (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
In this study, we demonstrate the effectiveness of a cancer type specific FrAmeShifT (FAST) vaccine. A murine breast cancer (mBC) FAST vaccine and a murine pancreatic cancer (mPC) FAST vaccine were tested in the 4T1 breast cancer syngeneic mouse model. The mBC FAST vaccine, both with and without check point inhibitors (CPI), significantly slowed tumor growth, reduced pulmonary metastasis and increased the cell-mediated immune response. In terms of tumor volumes, the mPC FAST vaccine was comparable to the untreated controls. However, a significant difference in tumor volume did emerge when the mPC vaccine was used with CPI. The collective data indicated that the immune checkpoint blockade therapy was only beneficial with suboptimal neoantigens. More importantly, the FAST vaccine, though requiring notably less resources, performed similarly to the personalized version of the frameshift breast cancer vaccine in the same mouse model. Furthermore, because the frameshift peptide (FSP) array provided a strong rationale for a focused vaccine, the FAST vaccine can theoretically be expanded and translated to any human cancer type. Overall, the FAST vaccine is a promising treatment that would provide the most benefit to patients while eliminating most of the challenges associated with current personal cancer vaccines.
ContributorsMurphy, Sierra Nicole (Author) / Johnston, Stephen (Thesis director) / Peterson, Milene (Committee member) / School of Mathematical and Statistical Sciences (Contributor) / School of Molecular Sciences (Contributor) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
The North American Free Trade Agreement was passed by the U.S. Congress in November 1993. The United States had decided that a regional trade approach would be more beneficial than bilateral trade with its neighbors. This move accepted Mexico as an equal economic partner with the United States and Canada despite their economic deficiencies. The NAFTA agreement came into effect on January 1, 1994. Canada, Mexico, and the United States agreed to eliminate tariffs on roughly ninety-nine percent of internationally traded goods by the end of 2004. The agreement was also significant because the three nations took a big step in further liberalizing Foreign Direct Investment policies. NAFTA resulted in what is today a $19 trillion regional market with over 470 million consumers. The U.S. Chamber of Commerce estimates that six million U.S. jobs depend on trade with Mexico and another eight million jobs depend on trade with Canada. As seen, economic interests clearly dominated the NAFTA debate on all fronts. There still were other domestic political interests that further pushed the United States to seek regional integration with Canada and Mexico. Drugs, energy, pollution, and the threat of American jobs as a result of Mexico’s low wages were all major issues considered in the United States at the time. The issues noted above can be closely linked to the United States’ national security interests. Policy-makers and treaty negotiators constantly connected the passage of this agreement to the long-term interests of the United States. For NAFTA to have a chance in the first place, all operational concerns had to have been resolved first. The governing structure for management of the activities that fall under NAFTA’s umbrella was a huge prerequisite. Additionally, separate side agreements with Canada and Mexico had to be negotiated so that the they would offset any future problems NAFTA might create for the United States. Although a challenge, it all came together perfectly and the passage was successfully implemented. Taking everything into consideration, the United States should stray way from its’ isolationist ways and pursue a regional agreement like NAFTA for the betterment of all North Americans.
ContributorsIvanov, Martin (Author) / Ackroyd, William (Thesis director) / Rivero, Tony (Committee member) / School of Social and Behavioral Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
The pace at which technology advances beats many marketers’ responses; in the music industry, technological advancements have driven the changes in music consumption and music marketing, which has created a need for a different marketing approach. Specifically, the digitalization of music has changed the way it is consumed—consumers now have access to digital music libraries with millions of songs directly on their phones, making streaming the driver of today’s music consumption—and social media has played an important role in the need for changes in music marketing. Additionally, the consumers behind this shift from buying physical albums to streaming music are millennials and Gen Z. For this reason, both groups were focused on in this research.
For decades, the music industry followed a structured business model that relied on the sale of albums in order for musicians and record labels to see revenues. Due to the rise of streaming services and changes in consumer behavior, this is no longer the case. Aldo Cundari argues that because of these changes, we are in the Customer Era of marketing, where marketers must use customer-centricity in order to drive consumers to want to engage with brands, as we now face informed and empowered consumers. Taking this theory and Vargo and Lusch’s argument that marketing is now service-centered—where consumers should be a part of the production process through co-creation of value, relationships, and customization of offerings—requires an analysis of the drivers of digital streaming and approaching them through a value-adding approach, finding the right channel of distribution, determining potential brand advocates, and assessing their preferences and behavior.
This paper first examines the history of music consumption, assesses today’s consumption, the shift from buying to streaming, and uncovers the indirect relationship between music and social media. I find that millennials and Generation Z are the drivers behind streaming, so primary research via a questionnaire is conducted to further evaluate their preferences and what they value in order to recommend customer-centric marketing strategies for music marketing. It was found that today’s consumer is a heavy social media user, integrates his/her social media and music consumption, and that the best channel of distribution is Instagram. To allow the consumer to co-create value, I found that the use of brand advocates and organic influencer marketing (through playlists and sponsored posts) is needed in the dynamic of today’s music industry.
For decades, the music industry followed a structured business model that relied on the sale of albums in order for musicians and record labels to see revenues. Due to the rise of streaming services and changes in consumer behavior, this is no longer the case. Aldo Cundari argues that because of these changes, we are in the Customer Era of marketing, where marketers must use customer-centricity in order to drive consumers to want to engage with brands, as we now face informed and empowered consumers. Taking this theory and Vargo and Lusch’s argument that marketing is now service-centered—where consumers should be a part of the production process through co-creation of value, relationships, and customization of offerings—requires an analysis of the drivers of digital streaming and approaching them through a value-adding approach, finding the right channel of distribution, determining potential brand advocates, and assessing their preferences and behavior.
This paper first examines the history of music consumption, assesses today’s consumption, the shift from buying to streaming, and uncovers the indirect relationship between music and social media. I find that millennials and Generation Z are the drivers behind streaming, so primary research via a questionnaire is conducted to further evaluate their preferences and what they value in order to recommend customer-centric marketing strategies for music marketing. It was found that today’s consumer is a heavy social media user, integrates his/her social media and music consumption, and that the best channel of distribution is Instagram. To allow the consumer to co-create value, I found that the use of brand advocates and organic influencer marketing (through playlists and sponsored posts) is needed in the dynamic of today’s music industry.
ContributorsArteaga, Maria Jesus (Author) / Eaton, John (Thesis director) / Olsen, Douglas (Committee member) / Department of Marketing (Contributor) / Department of Economics (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
Motorcycle fatalities have been increasing at a faster rate than the number of motorcycles being registered in the United States. There is limited analysis on the causes of fatal motorcycle crashes, specifically regarding different demographics, certain driver behavior, and various crash characteristics. It is important to be aware of how these factors relate to each other during a fatal motorcycle crash. This analysis focuses on these factors and explores potential steps to decrease motorcycle fatality rates using research and data from the Fatality Analysis Reporting System (FARS) from the National Highway Traffic Safety Administration (NHTSA), and data from the National Household Travel Survey (NHTS). Based on this data, there are noticeable trends between different genders and age groups. According to the analysis, males have a higher fatality rate than females, and their fatal crashes tend to involve multiple driver infractions such as drinking, speeding, not wearing a helmet, and driving without a license. Similarly, younger drivers have a higher fatality rate than older drivers, and their fatal crashes tend to involve multiple driver infractions. Although older drivers involved in fatal crashes usually drive more cautiously, they tend to be involved in single-vehicle crashes more often than younger drivers. Moving forward, implementing certain training programs directed towards particular demographics has the potential to decrease motorcycle rider fatalities.
ContributorsMoran, Sarah Elizabeth (Co-author) / Santilli, Amy (Co-author) / Pendyala, Ram (Thesis director) / Khoeini, Sara (Committee member) / Industrial, Systems & Operations Engineering Prgm (Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
Ensuring that people across the globe have enough water and electricity are two large issues that continue to grow. This study performs a test on whether using solar photovoltaic modules to shade water can potentially help diminish the issues of water and power. Using the setup of a PV module shading water, a stand-alone PV module, and unshaded water, it was found that shading water can reduce evaporation and lower PV module operating temperature at the same time. Using averaged data from two days of testing, the volume per unit surface area of water that evaporated per hour was 0.319 cm3/cm2 less for the shaded water compared to the unshaded water. The evaporation rates found in the experiment are compared to those of Lake Mead to see the amount of water lost on a large scale. For the operating temperature of the PV module, the module used for shading had a consistently lower temperature than the stand-alone module. On the first day, the shading module had an average temperature 5.1 C lower than the stand-alone module average temperature. On day two, the shading module had an average temperature 3.4 C lower than the stand-alone module average temperature. Using average temperatures between the two days from 10:30am and 4:45pm, the average daily temperature of the panel used for shading was 4.5C less than the temperature of the stand-alone panel. These results prove water shading by solar PV modules to be effective in reducing evaporation and lowering module operating temperature. Last, suggestions for future studies are discussed, such as performance analysis of the PV modules in this setting, economic analysis of using PV modules as shading, and the isolation of the different factors of evaporation (temperature, wind speed, and humidity).
ContributorsLee, John C (Author) / Phelan, Patrick (Thesis director) / Roedel, Ronald (Committee member) / Dean, W.P. Carey School of Business (Contributor) / Mechanical and Aerospace Engineering Program (Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
Extensive literature exists examining the maximum mitigation potential of
biochar. This research has found biochar to hold massive potential as a means of stabilizing current levels of atmospheric carbon. Furthermore, the research and resources to massively expand biochar production exist, yet one could easily argue the industry is not expanding quickly enough given its known potential benefits. This paper serves to address this lack of growth, and identified a lack of formalized networks for knowledge and innovation exchanges amongst biochar production firms as a leading obstacle to quick expansion. I focus on two particular biochar production firms operating in vastly different contexts and analyze both through a conceptual framework known as “knowledge networks”. In depth literature on the topic of knowledge networks highlight the dynamics of exchange, including the obstacles in establishing such a network. I applied the findings from a multitude of case studies centered around knowledge networks to biochar production, asserting that exchange networks centered around reciprocity would serve as a catalyst to the growth of the biochar industry. I also assert that public research institutions such as Arizona State University would play a critical role in such a network, as they would serve as a mutual party connecting two private entities. Private biochar production firms around the world would be exposed to new knowledge and information that would serve to maximize the energy value of their product while reducing the environmental externalities associated with their process.
biochar. This research has found biochar to hold massive potential as a means of stabilizing current levels of atmospheric carbon. Furthermore, the research and resources to massively expand biochar production exist, yet one could easily argue the industry is not expanding quickly enough given its known potential benefits. This paper serves to address this lack of growth, and identified a lack of formalized networks for knowledge and innovation exchanges amongst biochar production firms as a leading obstacle to quick expansion. I focus on two particular biochar production firms operating in vastly different contexts and analyze both through a conceptual framework known as “knowledge networks”. In depth literature on the topic of knowledge networks highlight the dynamics of exchange, including the obstacles in establishing such a network. I applied the findings from a multitude of case studies centered around knowledge networks to biochar production, asserting that exchange networks centered around reciprocity would serve as a catalyst to the growth of the biochar industry. I also assert that public research institutions such as Arizona State University would play a critical role in such a network, as they would serve as a mutual party connecting two private entities. Private biochar production firms around the world would be exposed to new knowledge and information that would serve to maximize the energy value of their product while reducing the environmental externalities associated with their process.
ContributorsChernak, Jarod Ross (Author) / Chhetri, Netra (Thesis director) / Henderson, Mark (Committee member) / School of Sustainability (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
Perfection’s Reflection: Influencers on Bodybuilder Behavior is an honors thesis project that provides insight on the impact of influencers and may be a value to those who wish to be influential to competitive bodybuilders. Six current and former competitive bodybuilders explained the impact of influencers in seven key themes: 1.) Body dissatisfaction, 2.) Inspiration, 3.) Imitation, 4.) Motivation, 5.) Skepticism and distrust, 6.) Information, and 7.) Avoidance. These seven key themes were identified throughout three stages of the bodybuilders’ journeys, “The Beginning,” during their early childhood to high school years, “The Middle,” the start of their bodybuilding careers, and “The End,” the present day. It is concluded that influencers may impact competitive bodybuilders differently based on the stage of their journeys and to be influential, one should provide the ideal impact based on bodybuilders’ stage of their journeys.
ContributorsCaldwell, Kiara (Author) / Gray, Nancy (Thesis director) / Aguila, Holly (Committee member) / Department of Marketing (Contributor) / College of Health Solutions (Contributor) / Dean, W.P. Carey School of Business (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
When limited for iron, Escherichia coli secretes a siderophore, enterobactin, to solubilize and intake extracellular Fe3+ by a TonB-dependent high-affinity pathway. Consequently, E. coli tonB mutants grow poorly on a medium limited for iron. Upon longer incubation, however, faster growing colonies emerge and overcome this growth defect. The work presented in this paper reports and characterizes these faster growing colonies (revertants) in an attempt to dissect the mechanism by which they overcome the TonB deficiency. Genomic analysis revealed mutations in yejM, a putative inner-to-outer membrane cardiolipin transporter, which are responsible for the faster growth phenotype in a tonB mutant background. Further characterization of the revertants revealed that they display hypersensitivity to vancomycin, a large antibiotic that is normally precluded from entering E. coli cells, and leaked periplasmic proteins into the culture supernatant, indicating a compromised outer membrane permeability barrier. All phenotypes were reversed by supplying the wild type copy of yejM on a plasmid, suggesting that yejM mutations are solely responsible for the observed phenotypes. In the absence of wild type tonB, however, the deletion of all known of cardiolipin synthase genes (clsABC) did not produce the phenotype similar to mutations in the yejM gene, suggesting the absence of cardiolipin from the outer membrane per se is not responsible for the increased outer membrane permeability. These data show that a defect in lipid biogenesis and transport can compromise outer membrane permeability barrier to allow siderophore intake and that YejM may have additional roles other than transporting cardiolipin.
ContributorsQiu, Nan (Author) / Misra, Rajeev (Thesis director) / Bean, Heather (Committee member) / Yu, Julian (Committee member) / School of Molecular Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05