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American Logistics Aid Network (ALAN) is a non-profit logistics aid firm that provides supply chain assistance to non-profit organizations in times of crisis. It acts somewhat as a non-profit 3PL, connecting nonprofits seeking humanitarian aid goods, materials handling equipment, warehousing, logistics transportation, and expertise to an outstanding network of partner

American Logistics Aid Network (ALAN) is a non-profit logistics aid firm that provides supply chain assistance to non-profit organizations in times of crisis. It acts somewhat as a non-profit 3PL, connecting nonprofits seeking humanitarian aid goods, materials handling equipment, warehousing, logistics transportation, and expertise to an outstanding network of partner companies and organizations who help to deliver on their requests. In June of 2020, our team began an internship to identify and implement key process improvements for ALAN’s internal and external processes. This thesis is a summary of our findings, our solutions proposal, and their applicability to other non-profit organizations.

ContributorsTrevino, Melissa (Co-author) / Cantrell, Ryan (Co-author) / Shultz, Delaney (Co-author) / Keane, Katy (Thesis director) / Baskin, Connor (Committee member) / Dean, W.P. Carey School of Business (Contributor) / School of International Letters and Cultures (Contributor) / School of Sustainability (Contributor) / Department of Supply Chain Management (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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This thesis proposes an extension of David Lewis's causal influence account of causation, providing a method to calculate the `degrees of causal influence.' By providing a quantitative approach to causal influence, I find that that the influence approach can assess statements that involve causal redundancies, allowing the assessor to attribute

This thesis proposes an extension of David Lewis's causal influence account of causation, providing a method to calculate the `degrees of causal influence.' By providing a quantitative approach to causal influence, I find that that the influence approach can assess statements that involve causal redundancies, allowing the assessor to attribute primary causal responsibility to the contending cause with a higher net influence value. The causal influence calculation also addresses criticisms towards Lewis's influence account, namely those involving `inert zones' of influence, the use of the term `might,' trumping versus symmetric overdetermination, and Lewis's clause requiring stepwise influence. This thesis also compares the results of causal influence in multiple toy cases including Two Rocks, both the asymmetric and symmetric variants, demonstrating that causal influence overcomes many of the core issues in Lewis's initial counterfactual account of causation. Using the asymmetric Two Rocks variant, this thesis also provides a detailed example of how to use the calculation and a discussion of the calculation's limitations. The main drawbacks of the quantitative method for causal influence seems to be the effort that it requires and issues in finding measurable qualities to compare the similarity/difference between possible worlds. Using the Two Rocks case, however, the causal influence calculation reaches the same conclusions as what Lewis suggests. A primary remaining issue is applying the calculation to instances of causation by omission, however this seems to only be a problem in using the equations rather than a problem within the idea of causal influence itself. Also, there may still be issues in justifying comparative overall similarity. However, this is an issue that both the counterfactual and influence accounts face.

ContributorsKha, Rachael Thuy-Trang (Author) / Watson, Jeffrey (Thesis director) / Botham, Thad (Committee member) / McElhoes, David (Committee member) / Historical, Philosophical & Religious Studies, Sch (Contributor) / Chemical Engineering Program (Contributor) / Economics Program in CLAS (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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We present the isotope yields of two post-explosion, three-dimensional 15 M_sol core-collapse supernova models, 15S and 15A, and compare them to the carbon, nitrogen, silicon, aluminum, sulfur, calcium, titanium, iron, and nickel isotopic compositions of presolar SiC stardust. We find that material from the interior of a core-collapse supernova can

We present the isotope yields of two post-explosion, three-dimensional 15 M_sol core-collapse supernova models, 15S and 15A, and compare them to the carbon, nitrogen, silicon, aluminum, sulfur, calcium, titanium, iron, and nickel isotopic compositions of presolar SiC stardust. We find that material from the interior of a core-collapse supernova can form a rare subset of SiC stardust, called SiC D grains, characterized by enrichments of the isotopes 13C and 15N. The innermost material of these core-collapse supernovae is operating in the neutrino-driven regime and undergoes rapid proton capture early in the explosion, providing these isotopes which are not present in such large abundances in other stardust grains of supernova origin.

ContributorsSchulte, Jack (Author) / Bose, Maitrayee (Thesis director) / Foy, Joseph (Committee member) / School of Earth and Space Exploration (Contributor) / Department of Physics (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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The purpose of this project is to analyze the current state of cancer nanomedicine and its challenges. Cancer is the second most deadly illness in the United States after heart disease. Nanomedicine, the use of materials between 1 and 100 nm to for the purpose of addressing healthcare-related problems, is

The purpose of this project is to analyze the current state of cancer nanomedicine and its challenges. Cancer is the second most deadly illness in the United States after heart disease. Nanomedicine, the use of materials between 1 and 100 nm to for the purpose of addressing healthcare-related problems, is particularly suited for treating it since nanoparticles have properties such as high surface area-to-volume ratios and favorable drug release profiles that make them more suitable for tasks such as consistent drug delivery to tumor tissue. The questions posed are: What are the current nanomedical treatments for cancer? What are the technical, social, and legal challenges related to nanomedical treatments and how can they be overcome? To answer the questions mentioned above, information from several scientific papers on nanomedical treatments for cancer as well as from social science journals was synthesized. Based on the findings, nanomedicine has a wide range of applications for cancer drug delivery, detection, and immunotherapy. The main technical challenge related to nanomedical treatments is navigating through biological barriers such as the mononuclear phagocyte system, the kidney, the blood-brain barrier, and the tumor microenvironment. Current approaches to meeting this challenge include altering the size, shape, and charge of nanoparticles for easier passage. The main social and legal challenge related to nanomedical treatments is the difficulty of regulating them due to factors such as the near impossibility of detecting nanowaste. Current approaches to meeting this challenge include the use of techniques such as scanning tunneling microscopy and atomic force microscopy to help distinguish nanowaste from the surroundings. More research will have to be done in these and other areas to enhance a major cancer-fighting tool.

ContributorsAbraham, Alfred Francy (Author) / Brian, Jennifer (Thesis director) / Liu, Yan (Committee member) / Materials Science and Engineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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Healthcare encounters may often be experienced by patients as cultural experiences as much as they are medicinal, creating different expectations and perceptions for each individual seeking care. This project sought to understand the experiences that Alaska Natives have with healthcare and how those experiences influenced their care. It provided a

Healthcare encounters may often be experienced by patients as cultural experiences as much as they are medicinal, creating different expectations and perceptions for each individual seeking care. This project sought to understand the experiences that Alaska Natives have with healthcare and how those experiences influenced their care. It provided a small window into the cultural relevance to healthcare for Alaska Natives by conducting interviews with participants from Sitka, Alaska. Interviews addressed three topics (or themes): linguistic and communication barriers, culturally specific care associated with individual tribes and patient-provider relationships. Although these topics, within the context of healthcare, have been well studied under the Native American - Alaska Native demographic umbrella, few projects target Alaska Natives specifically. This project was developed to specifically spotlight Alaska Natives to gain an understanding of their healthcare experiences.
ContributorsLarson, Skylar (Author) / McMullen, Mary (Thesis director) / Rowans, Leslie (Committee member) / College of Health Solutions (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
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This research examines the similarities and differences between relationships developed through interpersonal interactions within online fandom communities and those relationships developed through traditional in-person interactions such as those found within education or the workplace. Beyond the similarities and differences between the two forms of relationships, I discover phenomenologically what

This research examines the similarities and differences between relationships developed through interpersonal interactions within online fandom communities and those relationships developed through traditional in-person interactions such as those found within education or the workplace. Beyond the similarities and differences between the two forms of relationships, I discover phenomenologically what happens in the moment that two online friends meet in-person. To be precise, I analyze how individuals within fandoms categorize their relationships in terms of their willingness to confide in each other, their perceived honesty of themselves, and their mental image of one another and how it may have changed over the course of their relationship. We might expect that individuals maintaining a relationship through interactions within online fandom may maintain idealized images of their respective partners due to the aspect of self-censorship that is derived from asynchronous communication. Additionally, we might expect that while trust may be built upon this exaggerated image of one’s partner, a disruption in this image formed through an in-person interaction could potentially result in said trust crumbling. Using a qualitative analysis of three individuals participating within various fandom communities. Thus, we predict that individuals within online relationships take steps to build an idealized version of oneself that might not fully reflect an individual’s actual physical or mental character.

ContributorsLewkowitz, Aidan Alexander (Author) / Ingram-Waters, Mary (Thesis director) / Williams, Wendy (Committee member) / Department of Finance (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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The summer of protests which began with George Floyd’s murder at the hands of a white police officer in May 2020 reignited a national reckoning with the complicated story of race in America. America’s history of and enduring manifestations of systemic racism clash with American foundational principles of freedom and

The summer of protests which began with George Floyd’s murder at the hands of a white police officer in May 2020 reignited a national reckoning with the complicated story of race in America. America’s history of and enduring manifestations of systemic racism clash with American foundational principles of freedom and equality. One way in which this reckoning has manifested is in increased attention to monuments honoring controversial historical figures, particularly those with records of racist beliefs, attitudes, and actions, including slavery. In this thesis, I propose a guiding system of inquiry by which a controversial statue may be comprehensively evaluated and thoughtfully addressed. It drives at the heart of the issue by identifying and categorizing the six most significant and relevant attributes of the statue, with the ultimate goal of properly contextualizing a proposal for action. In order to test the efficacy of this evaluative model, I have selected the statue of Thomas Jefferson at the University of Missouri as a case study.

ContributorsClark, Kathryn (Author) / Seagrave, Adam (Thesis director) / Shonekan, Stephanie (Committee member) / School of Civic & Economic Thought and Leadership (Contributor) / Barrett, The Honors College (Contributor)
Created2021-12
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Caracals (Caracal caracal) are a felid species native to regions of southern Africa and western and central Asia. Despite their relatively high prevalence, the majority of research conducted on caracals has been undertaken on captive individuals, which encounter significantly different environments and exhibit different behaviors in comparison to caracals in

Caracals (Caracal caracal) are a felid species native to regions of southern Africa and western and central Asia. Despite their relatively high prevalence, the majority of research conducted on caracals has been undertaken on captive individuals, which encounter significantly different environments and exhibit different behaviors in comparison to caracals in the wild. Thereby, they likely have a vastly different virome. The goal of this study was to identify known and unknown DNA viruses associated with free-ranging caracals. Caracal fecal and organ samples were obtained from a caracal surveillance study undertaken in the Western Cape region of South Africa. Parasitic ticks found feeding on caracals were also obtained. Using a viral metagenomic informed approach, a novel circovirus (family Circoviridae) was detected and characterized in caracal fecal, kidney, spleen, and liver samples, as well as in ticks feeding on the caracals. To our knowledge, this is the first circovirus identified in caracals. The novel circovirus was determined to be closely related to a canine circovirus. These findings expand the knowledge of viral diversity and caracals and are greatly important to caracal conservation efforts as well as conservation efforts of other animals within their ecosystem.

ContributorsCollins, Courtney (Author) / Varsani, Arvind (Thesis director) / Dolby, Greer (Committee member) / Kraberger, Simona (Committee member) / Barrett, The Honors College (Contributor) / School of Molecular Sciences (Contributor)
Created2022-05
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Description
Low-level optimization is the process of handwriting key parts of applications in assembly code that is better than what can be generated from a higher-level language. In performance-intensive applications, this is key to ensuring efficient code. This is generally something that is taught in on the job training, but knowledge

Low-level optimization is the process of handwriting key parts of applications in assembly code that is better than what can be generated from a higher-level language. In performance-intensive applications, this is key to ensuring efficient code. This is generally something that is taught in on the job training, but knowledge of it improves college student’s skill sets and makes them more desirable employees I have created material for a course teaching this low-level optimization with assembly code. I specifically focus on the x86 architecture, as this is one of the most prolific computer architectures. The course contains a series of lecture videos, live coding videos, and structured programming assignments to support the learning objectives. This material is presented in an entirely autonomous way, which serves as remote learning material and can be easily added as supplemental material to an existing course.
ContributorsAbraham, Jacob (Author) / Meuth, Ryan (Thesis director) / Nakamura, Mutsumi (Committee member) / Barrett, The Honors College (Contributor) / Computer Science and Engineering Program (Contributor)
Created2022-05
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Dyslexia is a learning disability that negatively affects reading, writing, and spelling development at the word level in 5%-9% of children. The phenotype is variable and complex, involving several potential cognitive and physical concomitants such as sensory dysregulation and immunodeficiencies. The biological pathogenesis is not well-understood. Toward a better understanding

Dyslexia is a learning disability that negatively affects reading, writing, and spelling development at the word level in 5%-9% of children. The phenotype is variable and complex, involving several potential cognitive and physical concomitants such as sensory dysregulation and immunodeficiencies. The biological pathogenesis is not well-understood. Toward a better understanding of the biological drivers of dyslexia, we conducted the first joint exome and metabolome investigation in a pilot sample of 30 participants with dyslexia and 13 controls. In the metabolite analysis, eight metabolites of interest emerged (pyridoxine, kynurenic acid, citraconic acid, phosphocreatine, hippuric acid, xylitol, 2-deoxyuridine, and acetylcysteine). A metabolite-metabolite interaction analysis identified Krebs cycle intermediates that may be implicated in the development of dyslexia. Gene ontology analysis based on exome variants resulted in several pathways of interest, including the sensory perception of smell (olfactory) and immune system-related responses. In the joint exome and metabolite analysis, the olfactory transduction pathway emerged as the primary pathway of interest. Although the olfactory transduction and Krebs cycle pathways have not previously been described in the dyslexia literature, these pathways have been implicated in other neurodevelopmental disorders including autism spectrum disorder and obsessive-compulsive disorder, suggesting the possibility of these pathways playing a role in dyslexia as well. Immune system response pathways, on the other hand, have been implicated in both dyslexia and other neurodevelopmental disorders.

ContributorsNandakumar, Rohit (Author) / Dinu, Valentin (Thesis director) / Peter, Beate (Committee member) / Barrett, The Honors College (Contributor) / College of Health Solutions (Contributor)
Created2022-05